M J Obregón

Author PubWeight™ 30.66‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Is neuropsychological development related to maternal hypothyroidism or to maternal hypothyroxinemia? J Clin Endocrinol Metab 2000 2.37
2 Replacement therapy for hypothyroidism with thyroxine alone does not ensure euthyroidism in all tissues, as studied in thyroidectomized rats. J Clin Invest 1995 1.47
3 The type 2 iodothyronine deiodinase is expressed primarily in glial cells in the neonatal rat brain. Proc Natl Acad Sci U S A 1997 1.46
4 Only the combined treatment with thyroxine and triiodothyronine ensures euthyroidism in all tissues of the thyroidectomized rat. Endocrinology 1996 1.30
5 Congenital hypothyroidism, as studied in rats. Crucial role of maternal thyroxine but not of 3,5,3'-triiodothyronine in the protection of the fetal brain. J Clin Invest 1990 1.20
6 Thyroid hormones in tissues from fetal and adult rats. Endocrinology 1994 1.04
7 The rat placenta and the transfer of thyroid hormones from the mother to the fetus. Effects of maternal thyroid status. Endocrinology 1992 0.93
8 Thyroid hormones and 5'-deiodinase in the rat fetus late in gestation: effects of maternal hypothyroidism. Endocrinology 1991 0.93
9 Regulation of iodothyronine deiodinase activity as studied in thyroidectomized rats infused with thyroxine or triiodothyronine. Endocrinology 1997 0.92
10 Developmental changes in rat brain 5'-deiodinase and thyroid hormones during the fetal period: the effects of fetal hypothyroidism and maternal thyroid hormones. Pediatr Res 1988 0.92
11 Triiodothyronine amplifies the adrenergic stimulation of uncoupling protein expression in rat brown adipocytes. Am J Physiol Endocrinol Metab 2000 0.88
12 Effects of thyroid hormone on the androgenic expression of KAP gene in mouse kidney. Mol Cell Endocrinol 1996 0.85
13 Presence and mRNA expression of T3 receptors in differentiating rat brown adipocytes. Mol Cell Endocrinol 1996 0.85
14 Presence of growth factors-induced type III iodothyronine 5-deiodinase in cultured rat brown adipocytes. Endocrinology 1995 0.83
15 Iodothyronine 5'-deiodinase activity and thyroid hormone content in brown adipose tissue during the breeding cycle of the rat. Biochem J 1988 0.82
16 Effects of iodine deficiency on thyroid hormone metabolism and the brain in fetal rats: the role of the maternal transfer of thyroxin. Am J Clin Nutr 1993 0.82
17 The role of type I and type II 5' deiodinases on hexachlorobenzene-induced alteration of the hormonal thyroid status. Toxicology 2005 0.81
18 T3 potentiates the adrenergic stimulation of type II 5'-deiodinase activity in cultured rat brown adipocytes. Am J Physiol 1996 0.80
19 Norepinephrine, tri-iodothyronine and insulin upregulate glyceraldehyde-3-phosphate dehydrogenase mRNA during Brown adipocyte differentiation. Eur J Endocrinol 1999 0.80
20 The expression of the sodium/iodide symporter is up-regulated in the thyroid of fetuses of iodine-deficient rats. Endocrinology 2001 0.80
21 Iodothyronine 5'-deiodinase activity in rat brown adipose tissue during development. Biochim Biophys Acta 1987 0.79
22 Thyroid hormone controls the cell-specific expression of the kidney androgen-regulated protein gene in S3 mouse kidney cells. Endocrinology 1994 0.79
23 Norepinephrine potentiates the mitogenic effect of growth factors in quiescent brown preadipocytes: relationship with uncoupling protein messenger ribonucleic acid expression. Endocrinology 1997 0.78
24 Iodothyronine deiodinase activities in fetal rat tissues at several levels of iodine deficiency: a role for the skin in 3,5,3'-triiodothyronine economy? Endocrinology 1998 0.78
25 Transcriptional activation of type III inner ring deiodinase by growth factors in cultured rat brown adipocytes. Endocrinology 1998 0.78
26 Malic enzyme gene expression in differentiating brown adipocytes: regulation by insulin and triiodothyronine. Endocrinology 1993 0.78
27 Cerebral hypothyroidism in rats with adult-onset iodine deficiency. Endocrinology 1984 0.77
28 Differential effects of hypothyroidism on the specific uptake of growth hormone and prolactin by the rat liver. Endocrinology 1981 0.77
29 Generalized deficiency of 3,5,3'-triiodo-L-thyronine (T3) in tissues from rats on a low iodine intake, despite normal circulating T3 levels. Acta Endocrinol (Copenh) 1989 0.77
30 Maternal thyroid hormones during pregnancy: effects on the fetus in congenital hypothyroidism and in iodine deficiency. Adv Exp Med Biol 1991 0.77
31 Tissue-specific patterns of changes in 3,5,3'-triiodo-L-thyronine concentrations in thyroidectomized rats infused with increasing doses of the hormone. Which are the regulatory mechanisms? Biochimie 1999 0.76
32 Maternal diabetes mellitus, a rat model for nonthyroidal illness: correction of hypothyroxinemia with thyroxine treatment does not improve fetal thyroid hormone status. Thyroid 1997 0.76
33 Maternal nonthyroidal illness and fetal thyroid hormone status, as studied in the streptozotocin-induced diabetes mellitus rat model. Endocrinology 1997 0.75
34 Analytical artifacts in radioimmunoassay of L-thyroxin in human milk. Clin Chem 1982 0.75
35 Thyroid hormones and 5'-deiodinase activity in neonatal undernourished rats. Endocrinology 1992 0.75
36 Thyroxine radioimmunoassay for population surveys using dried blood: modifications of a highly sensitive method. Ann Clin Biochem 1982 0.75
37 Decreased T4 to T3 conversion in tissues of streptozotocin-diabetic rats. Acta Endocrinol (Copenh) 1984 0.75
38 Comparison of maternal to fetal transfer of 3,5,3'-triiodothyronine versus thyroxine in rats, as assessed from 3,5,3'-triiodothyronine levels in fetal tissues. Acta Endocrinol (Copenh) 1989 0.75
39 Effects of thyroid hormone deiodination on regulation of thyroid axis in undernourished rats. Am J Physiol 1994 0.75
40 Influence of type II 5' deiodinase on TSH content in diabetic rats. J Physiol Biochem 2001 0.75
41 Maternal hypothyroidism and fetal chondro-osseous development in rats. Biol Neonate 1991 0.75
42 Thyroid hormones in human tumoral and normal nervous tissues. Brain Res 1998 0.75
43 Displacement of T4 from transthyretin by the synthetic flavonoid EMD 21388 results in increased production of T3 from T4 in rat dams and fetuses. Endocrinology 1996 0.75
44 Thyroglobulin-like antigens in a goiter with impaired thyroglobulin biosynthesis. J Clin Endocrinol Metab 1974 0.75
45 Age-dependent adaptation of the liver thyroid status and recovery of serum levels and hepatic insulin-like growth factor-I expression in neonatal and adult diabetic rats. Metabolism 2003 0.75