Published in Clin Microbiol Rev on January 01, 1988
A Legionella pneumophila gene encoding a species-specific surface protein potentiates initiation of intracellular infection. Infect Immun (1989) 3.18
Growth of Legionella pneumophila in Acanthamoeba castellanii enhances invasion. Infect Immun (1994) 3.06
Detection of Legionella species in respiratory specimens using PCR with sequencing confirmation. J Clin Microbiol (2000) 2.90
Legionella pneumophila mip gene potentiates intracellular infection of protozoa and human macrophages. Proc Natl Acad Sci U S A (1992) 2.87
Phenotypic modulation by Legionella pneumophila upon infection of macrophages. Infect Immun (1993) 2.79
Resuscitation of viable but nonculturable Legionella pneumophila Philadelphia JR32 by Acanthamoeba castellanii. Appl Environ Microbiol (1997) 2.45
Pulsed field electrophoresis of genomic restriction fragments for the detection of nosocomial Legionella pneumophila in hospital water supplies. J Clin Microbiol (1991) 1.89
Identification of mip-like genes in the genus Legionella. Infect Immun (1990) 1.87
PCR for bioaerosol monitoring: sensitivity and environmental interference. Appl Environ Microbiol (1995) 1.75
Legionella pneumophila htpAB heat shock operon: nucleotide sequence and expression of the 60-kilodalton antigen in L. pneumophila-infected HeLa cells. Infect Immun (1990) 1.72
A Dot/Icm-translocated ankyrin protein of Legionella pneumophila is required for intracellular proliferation within human macrophages and protozoa. Mol Microbiol (2008) 1.61
Periplasmic copper-zinc superoxide dismutase of Legionella pneumophila: role in stationary-phase survival. J Bacteriol (1996) 1.57
Legionella contamination of dental-unit waters. Appl Environ Microbiol (1995) 1.54
Cloning and genetic characterization of the flagellum subunit gene (flaA) of Legionella pneumophila serogroup 1. Infect Immun (1995) 1.47
Legionella pneumophila type II protein secretion promotes virulence in the A/J mouse model of Legionnaires' disease pneumonia. Infect Immun (2004) 1.46
Detection of Legionella species in sewage and ocean water by polymerase chain reaction, direct fluorescent-antibody, and plate culture methods. Appl Environ Microbiol (1993) 1.42
Influence of site specifically altered Mip proteins on intracellular survival of Legionella pneumophila in eukaryotic cells. Infect Immun (1995) 1.42
Legionella pneumophila mutants that are defective for iron acquisition and assimilation and intracellular infection. Infect Immun (1996) 1.40
Secreted enzymatic activities of wild-type and pilD-deficient Legionella pneumophila. Infect Immun (2000) 1.37
Type II protein secretion is a subset of the PilD-dependent processes that facilitate intracellular infection by Legionella pneumophila. Infect Immun (2001) 1.36
Rapid method for enumeration of viable Legionella pneumophila and other Legionella spp. in water. Appl Environ Microbiol (2005) 1.35
Detection of Legionella species in reclaimed water and air with the EnviroAmp Legionella PCR kit and direct fluorescent antibody staining. Appl Environ Microbiol (1995) 1.25
Cytotoxicity of extracellular Legionella pneumophila. Infect Immun (1994) 1.25
Proteomic characterization of the whole secretome of Legionella pneumophila and functional analysis of outer membrane vesicles. Infect Immun (2008) 1.24
Secondary immunity to Legionella pneumophila and Th1 activity are suppressed by delta-9-tetrahydrocannabinol injection. Infect Immun (1994) 1.21
Legionella pneumophila major acid phosphatase and its role in intracellular infection. Infect Immun (2001) 1.20
The Legionella pneumophila tatB gene facilitates secretion of phospholipase C, growth under iron-limiting conditions, and intracellular infection. Infect Immun (2005) 1.20
The iron superoxide dismutase of Legionella pneumophila is essential for viability. J Bacteriol (1994) 1.18
Infection of macrophage-like cells by Legionella species that have not been associated with disease. Infect Immun (1996) 1.17
Sequence determination and mutational analysis of the lly locus of Legionella pneumophila. Infect Immun (1994) 1.15
Discovery of a nonclassical siderophore, legiobactin, produced by strains of Legionella pneumophila. J Bacteriol (2000) 1.07
The purified and recombinant Legionella pneumophila chaperonin alters mitochondrial trafficking and microfilament organization. Infect Immun (2009) 1.07
De novo synthesis of Legionella pneumophila antigens during intracellular growth in phagocytic cells. Infect Immun (1996) 1.06
Legionella pneumophila inhibits protein synthesis in Chinese hamster ovary cells. Infect Immun (1991) 1.05
Cysteine metabolism in Legionella pneumophila: characterization of an L-cystine-utilizing mutant. Appl Environ Microbiol (2006) 1.05
Cloning, genetic analysis, and nucleotide sequence of a determinant coding for a 19-kilodalton peptidoglycan-associated protein (Ppl) of Legionella pneumophila. Infect Immun (1991) 1.04
Targeting species-specific low-affinity 16S rRNA binding sites by using peptide nucleic acids for detection of Legionellae in biofilms. Appl Environ Microbiol (2006) 0.99
Analysis of Legionella pneumophila serogroup 6 strains isolated from a hospital warm water supply over a three-year period by using genomic long-range mapping techniques and monoclonal antibodies. Appl Environ Microbiol (1991) 0.99
The cytochrome c maturation locus of Legionella pneumophila promotes iron assimilation and intracellular infection and contains a strain-specific insertion sequence element. Infect Immun (2002) 0.99
Characterization of a major 31-kilodalton peptidoglycan-bound protein of Legionella pneumophila. J Bacteriol (1990) 0.98
The PmrA/PmrB two-component system of Legionella pneumophila is a global regulator required for intracellular replication within macrophages and protozoa. Infect Immun (2008) 0.97
Comparative Genomics Reveal That Host-Innate Immune Responses Influence the Clinical Prevalence of Legionella pneumophila Serogroups. PLoS One (2013) 0.97
Phase-variable expression of lipopolysaccharide contributes to the virulence of legionella pneumophila. J Exp Med (1998) 0.96
Isolation of a gene encoding a novel spectinomycin phosphotransferase from Legionella pneumophila. Antimicrob Agents Chemother (1997) 0.95
Distribution, expression, and long-range mapping of legiolysin gene (lly)-specific DNA sequences in legionellae. Infect Immun (1991) 0.94
The Lly protein protects Legionella pneumophila from light but does not directly influence its intracellular survival in Hartmannella vermiformis. Appl Environ Microbiol (1995) 0.90
Heterotrophic bacteria in an air-handling system. Appl Environ Microbiol (1992) 0.89
Characterization of members of the Legionellaceae family by automated ribotyping. J Clin Microbiol (2003) 0.88
Characterization of Legionella pneumophila isolated from environmental water and ashiyu foot spa. Biomed Res Int (2013) 0.86
Legionella pneumophila lipopolysaccharide activates the classical complement pathway. Infect Immun (1992) 0.86
Invasion of eukaryotic cells by Legionella pneumophila: A common strategy for all hosts? Can J Infect Dis (1997) 0.85
Immune Control of Legionella Infection: An in vivo Perspective. Front Microbiol (2011) 0.84
Legionella pneumophila requires polyamines for optimal intracellular growth. J Bacteriol (2011) 0.84
Intracellular survival and expression of virulence determinants of Legionella pneumophila. Infection (1991) 0.82
Antibody-mediated enhancement of Legionella pneumophila-induced interleukin 1 activity. Infect Immun (1993) 0.81
Two-step scheme for rapid identification and differentiation of Legionella pneumophila and non-Legionella pneumophila species. J Clin Microbiol (2009) 0.79
V gamma 9V delta 2 T cells in human legionellosis. Clin Diagn Lab Immunol (2001) 0.79
Molecular approaches for the classification of microbial pathogens of public health significance. Biomed Res Int (2014) 0.75
Legionella pneumonia in the Niagara Region, Ontario, Canada: a case series. J Med Case Rep (2016) 0.75
Legionnaires' disease: isolation of a bacterium and demonstration of its role in other respiratory disease. N Engl J Med (1977) 25.00
Legionnaires' disease: description of an epidemic of pneumonia. N Engl J Med (1977) 24.44
Charcoal-yeast extract agar: primary isolation medium for Legionella pneumophila. J Clin Microbiol (1979) 15.15
Primary isolation media for Legionnaires disease bacterium. J Clin Microbiol (1978) 11.86
Pittsburgh pneumonia agent: direct isolation from human lung tissue. J Infect Dis (1980) 11.36
Classification of the Legionnaires' disease bacterium: Legionella pneumophila, genus novum, species nova, of the family Legionellaceae, familia nova. Ann Intern Med (1979) 9.90
The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes. J Exp Med (1983) 8.82
Demonstration of the agent of Legionnaires' disease in tissue. N Engl J Med (1977) 8.50
Four serogroups of Legionnaires' disease bacteria defined by direct immunofluorescence. Ann Intern Med (1979) 7.89
Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae. J Clin Pathol (1980) 7.72
Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes. J Exp Med (1983) 7.65
Genetic structure of populations of Legionella pneumophila. J Bacteriol (1985) 7.30
Ecological distribution of Legionella pneumophila. Appl Environ Microbiol (1981) 7.16
Isolation of Legionella spp. from environmental water samples by low-pH treatment and use of a selective medium. J Clin Microbiol (1981) 6.88
Isolation of Legionella pneumophila from nonepidemic-related aquatic habitats. Appl Environ Microbiol (1979) 6.82
An outbreak of Legionnaires' disease associated with a contaminated air-conditioning cooling tower. N Engl J Med (1980) 6.64
Development of a chemically defined liquid medium for growth of Legionella pneumophila. J Clin Microbiol (1979) 6.10
Identification of 22 Legionella species and 33 serogroups with the slide agglutination test. J Clin Microbiol (1985) 5.81
Pontiac fever. An epidemic of unknown etiology in a health department: I. Clinical and epidemiologic aspects. Am J Epidemiol (1978) 5.54
Legionella pneumophila serogroup six: isolation from cases of legionellosis, identification by immunofluorescence staining, and immunological response to infection. J Clin Microbiol (1980) 4.90
Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J Cell Biol (1984) 4.88
Development of a standardized subgrouping scheme for Legionella pneumophila serogroup 1 using monoclonal antibodies. J Clin Microbiol (1986) 4.45
Growth of Legionella pneumophila in association with blue-green algae (cyanobacteria). Appl Environ Microbiol (1980) 4.24
Legionella gormanii sp. nov. J Clin Microbiol (1980) 4.12
Legionnaires' disease in a transplant unit: isolation of the causative agent from shower baths. Lancet (1980) 4.04
Phagocytosis of the Legionnaires' disease bacterium (Legionella pneumophila) occurs by a novel mechanism: engulfment within a pseudopod coil. Cell (1984) 4.00
The rickettsia-like organisms TATLOCK (1943) and HEBA (1959): bacteria phenotypically similar to but genetically distinct from Legionella pneumophila and the WIGA bacterium. Ann Intern Med (1980) 3.96
Virulent to avirulent conversion of Legionnaires' disease bacterium (Legionella pneumophila)--its effect on isolation techniques. J Infect Dis (1979) 3.96
Laboratory diagnosis of Legionnaires' disease. Am Rev Respir Dis (1980) 3.95
Legionella pneumonia in the United States: the distribution of serogroups and species causing human illness. J Infect Dis (1984) 3.81
A fifth serogroup of Legionella pneumophila. Ann Intern Med (1980) 3.80
Intracellular multiplication of Legionnaires' disease bacteria (Legionella pneumophila) in human monocytes is reversibly inhibited by erythromycin and rifampin. J Clin Invest (1983) 3.79
Legionella longbeachae species nova, another etiologic agent of human pneumonia. Ann Intern Med (1981) 3.78
Interaction between the legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone. J Clin Invest (1984) 3.59
Interaction of the Legionnaires' disease bacterium (Legionella pneumophila) with human phagocytes. I. L. pneumophila resists killing by polymorphonuclear leukocytes, antibody, and complement. J Exp Med (1981) 3.27
Water-related nosocomial pneumonia caused by Legionella pneumophila serogroups 1 and 10. J Infect Dis (1985) 3.16
Investigation and control of an outbreaks of legionnaires' disease in a district general hospital. Lancet (1981) 3.14
Glycine-containing selective medium for isolation of Legionellaceae from environmental specimens. Appl Environ Microbiol (1981) 3.00
Ultrastructure of lung in Legionnaires' disease. Observations of three biopsies done during the Vermont epidemic. Ann Intern Med (1979) 2.95
Hot water systems as sources of Legionella pneumophila in hospital and nonhospital plumbing fixtures. Appl Environ Microbiol (1982) 2.88
Amino acid requirements of Legionella pneumophila. J Clin Microbiol (1980) 2.88
Susceptibility of Legionella pneumophila to ofloxacin in vitro and in experimental Legionella pneumonia in guinea pigs. Antimicrob Agents Chemother (1985) 2.87
Legionnaires' disease: report of sixty-five nosocomially acquired cases of review of the literature. Medicine (Baltimore) (1980) 2.81
"Endotoxicity" of the Legionnaires' disease bacterium. Ann Intern Med (1979) 2.78
Immunologic diagnosis of Legionnaires' disease: cross-reactions with anaerobic and microaerophilic organisms and infections caused by them. J Infect Dis (1980) 2.76
Cocultivation of Legionella pneumophila and free-living amoebae. Appl Environ Microbiol (1982) 2.75
Legionella oakridgensis: unusual new species isolated from cooling tower water. Appl Environ Microbiol (1983) 2.70
Interferon-gamma-activated human monocytes inhibit the intracellular multiplication of Legionella pneumophila. J Immunol (1986) 2.62
Legionnaires' disease bacterium isolated in 1947. Ann Intern Med (1979) 2.61
Validation of Legionella pneumophila indirect immunofluorescence assay with epidemic sera. J Clin Microbiol (1981) 2.56
Causes of pneumonia presenting to a district general hospital. Thorax (1981) 2.55
Opportunistic lung infection due to "Pittsburgh Pneumonia Agent". N Engl J Med (1979) 2.49
Legionnaires' disease: unusual clinical and laboratory features. Ann Intern Med (1980) 2.46
Legionella jordanis: a new species of Legionella isolated from water and sewage. J Clin Microbiol (1982) 2.39
Comparative study of selective media for isolation of Legionella pneumophila from potable water. J Clin Microbiol (1982) 2.38
Isolation and characterization of the cytoplasmic and outer membranes of the Legionnaires' disease bacterium (Legionella pneumophila). J Exp Med (1985) 2.37
Rapid diagnosis of Legionnaires' disease by latex agglutination. Am Rev Respir Dis (1983) 2.35
A new Legionella species, Legionella feeleii species nova, causes Pontiac fever in an automobile plant. Ann Intern Med (1984) 2.35
Production of superoxide and hydrogen peroxide in medium used to culture Legionella pneumophila: catalytic decomposition by charcoal. Appl Environ Microbiol (1983) 2.34
Paleoepidemiologic investigation of Legionnaires disease at Wadsworth Veterans Administration Hospital by using three typing methods for comparison of legionellae from clinical and environmental sources. J Clin Microbiol (1986) 2.34
Cell-mediated immunity in Legionnaires' disease. J Clin Invest (1983) 2.30
A high molecular weight antigen in Legionnaires' disease bacterium: isolation and partial characterization. Ann Intern Med (1979) 2.29
Reactivity of serum from patients with suspected legionellosis against 29 antigens of legionellaceae and Legionella-like organisms by indirect immunofluorescence assay. J Infect Dis (1983) 2.28
Antibiotic treatment of guinea-pigs infected with agent of Legionnaires' disease. Lancet (1978) 2.28
Legionella pneumophila in water plumbing systems. Lancet (1982) 2.25
Legionnaires' disease in non-Legionnaires. A report of five cases. Ann Intern Med (1978) 2.18
Antimicrobial therapy of experimentally induced Legionnaires' disease in guinea pigs. Am Rev Respir Dis (1984) 2.18
Determination of antigenic relationships among legionellae and non-legionellae by direct fluorescent-antibody and immunodiffusion tests. J Clin Microbiol (1983) 2.16
Identification of a species-specific antigen in Legionella pneumophila by a monoclonal antibody. J Clin Microbiol (1984) 2.16
Diagnosis of Legionnaires' disease. An update of laboratory methods with new emphasis on isolation by culture. JAMA (1983) 2.14
Metal requirements of Legionella pneumophila. J Clin Microbiol (1981) 2.12
Dose-response of guinea pigs experimentally infected with aerosols of Legionella pneumophila. J Infect Dis (1980) 2.07
The pathology of Legionnaires' disease. Fourteen fatal cases from the 1977 outbreak in Vermont. Arch Pathol Lab Med (1978) 2.06
Enhanced chlorine resistance of tap water-adapted Legionella pneumophila as compared with agar medium-passaged strains. Appl Environ Microbiol (1985) 2.04
Mode of transmission of Legionella pneumophila. A critical review. Arch Intern Med (1986) 2.04
Cloning and expression of Legionella pneumophila antigens in Escherichia coli. Infect Immun (1984) 2.03
Dye-containing buffered charcoal-yeast extract medium for differentiation of members of the family Legionellaceae. J Clin Microbiol (1981) 2.03
Legionnaires' disease associated with a hospital water system: a cluster of 24 nosocomial cases. Ann Intern Med (1983) 2.00
Recognition of a second serogroup of Legionella longbeachae. J Clin Microbiol (1981) 1.97
Isolation of Legionella pneumophila from blood. Lancet (1979) 1.97
Evaluation of the Gen-Probe DNA probe for the detection of legionellae in culture. J Clin Microbiol (1986) 1.95
The pathology of the Legionella pneumonias. A review of 74 cases and the literature. Hum Pathol (1981) 1.94
Purification of Legionella pneumophila major outer membrane protein and demonstration that it is a porin. J Bacteriol (1985) 1.91
Second serogroup of Legionella feeleii strains isolated from humans. J Clin Microbiol (1985) 1.88
Legionella wadsworthii species nova: a cause of human pneumonia. Ann Intern Med (1982) 1.85
An outbreak in 1965 of severe respiratory illness caused by the Legionnaires' disease bacterium. J Infect Dis (1978) 1.84
Opportunistic pneumonia: a clinicopathological study of five cases caused by an unidentified acid-fast bacterium. N Engl J Med (1979) 1.84
Ecology of Legionella pneumophila within water distribution systems. Appl Environ Microbiol (1985) 1.83
Nosocomial Legionnaires' disease caused by aerosolized tap water from respiratory devices. J Infect Dis (1982) 1.81
Plasmid profiles of clinical and environmental isolates of Legionella pneumophila serogroup 1. J Clin Microbiol (1983) 1.79
Absence of siderophore activity in Legionella species grown in iron-deficient media. J Bacteriol (1983) 1.77
Pontiac fever: isolation of the etiologic agent (Legionella pneumophilia) and demonstration of its mode of transmission. Am J Epidemiol (1981) 1.77
Legionnaires' disease in renal-transplant recipients. Lancet (1978) 1.75
Nosocomial Legionnaires' disease. Epidemiologic demonstration of cooling towers as a source. JAMA (1985) 1.74
Defective production of monocyte-activating cytokines in lepromatous leprosy. J Exp Med (1984) 1.74
The kinetics of early inflammatory events during experimental pneumonia due to Legionella pneumophila in guinea pigs. J Infect Dis (1983) 1.67
Intracellular growth of Legionella pneumophila within Acanthamoeba castellanii Neff. Infect Immun (1984) 1.67
Susceptibility of Legionella pneumophila to chlorine in tap water. Appl Environ Microbiol (1983) 1.67