Published in Carlsberg Res Commun on January 01, 1988
Regulation of fatty acid biosynthesis in Escherichia coli. Microbiol Rev (1993) 5.09
Compilation of E. coli mRNA promoter sequences. Nucleic Acids Res (1993) 4.84
Analysis of the nucleotide sequence of the Streptomyces glaucescens tcmI genes provides key information about the enzymology of polyketide antibiotic biosynthesis. EMBO J (1989) 2.67
Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties. Proc Natl Acad Sci U S A (2007) 2.43
Structure and deduced function of the granaticin-producing polyketide synthase gene cluster of Streptomyces violaceoruber Tü22. EMBO J (1989) 2.30
A study of iterative type II polyketide synthases, using bacterial genes cloned from soil DNA: a means to access and use genes from uncultured microorganisms. J Bacteriol (1997) 1.95
Escherichia coli FadR positively regulates transcription of the fabB fatty acid biosynthetic gene. J Bacteriol (2001) 1.68
Overproduction of beta-ketoacyl-acyl carrier protein synthase I imparts thiolactomycin resistance to Escherichia coli K-12. J Bacteriol (1992) 1.57
Discovery of FabH/FabF inhibitors from natural products. Antimicrob Agents Chemother (2006) 1.51
Bacterial fatty acid synthesis and its relationships with polyketide synthetic pathways. Methods Enzymol (2009) 1.50
Crystal structure of beta-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of condensing enzymes. EMBO J (1998) 1.46
Thiolactomycin resistance in Escherichia coli is associated with the multidrug resistance efflux pump encoded by emrAB. J Bacteriol (1993) 1.38
3-Ketoacyl-acyl carrier protein synthase III from spinach (Spinacia oleracea) is not similar to other condensing enzymes of fatty acid synthase. Plant Physiol (1993) 1.38
Discovering the mechanism of action of novel antibacterial agents through transcriptional profiling of conditional mutants. Antimicrob Agents Chemother (2005) 1.35
Molecular evolution of aromatic polyketides and comparative sequence analysis of polyketide ketosynthase and 16S ribosomal DNA genes from various streptomyces species. Appl Environ Microbiol (2002) 1.32
Cloning, nucleotide sequence, and expression of the Escherichia coli fabD gene, encoding malonyl coenzyme A-acyl carrier protein transacylase. J Bacteriol (1992) 1.29
Primary structure of a cerulenin-binding beta-ketoacyl-[acyl carrier protein] synthase from barley chloroplasts. Proc Natl Acad Sci U S A (1991) 1.27
Response of Bacillus subtilis to cerulenin and acquisition of resistance. J Bacteriol (2001) 1.23
Cloning, characterization, and high-level expression in Escherichia coli of the Saccharopolyspora erythraea gene encoding an acyl carrier protein potentially involved in fatty acid biosynthesis. J Bacteriol (1991) 1.17
Myosin cross-reactive antigen of Streptococcus pyogenes M49 encodes a fatty acid double bond hydratase that plays a role in oleic acid detoxification and bacterial virulence. J Biol Chem (2010) 1.08
Overexpression of 3-ketoacyl-acyl-carrier protein synthase IIIs in plants reduces the rate of lipid synthesis. Plant Physiol (2001) 1.08
Duplication and functional divergence in the chalcone synthase gene family of Asteraceae: evolution with substrate change and catalytic simplification. Proc Natl Acad Sci U S A (1996) 1.05
The putative fabJ gene of Escherichia coli fatty acid synthesis is the fabF gene. J Bacteriol (1995) 1.02
Changes in the size and composition of intracellular pools of nonesterified coenzyme A and coenzyme A thioesters in aerobic and facultatively anaerobic bacteria. Appl Environ Microbiol (1997) 1.01
'FAS't inhibition of malaria. Biochem J (2004) 1.01
Cloning, sequencing, and analysis of the griseusin polyketide synthase gene cluster from Streptomyces griseus. J Bacteriol (1994) 0.99
Inhibition of the fungal fatty acid synthase type I multienzyme complex. Proc Natl Acad Sci U S A (2008) 0.97
Heterologous expression of an engineered biosynthetic pathway: functional dissection of type II polyketide synthase components in Streptomyces species. J Bacteriol (1995) 0.95
The fabJ-encoded beta-ketoacyl-[acyl carrier protein] synthase IV from Escherichia coli is sensitive to cerulenin and specific for short-chain substrates. Proc Natl Acad Sci U S A (1994) 0.95
Identification of antibiotic stress-inducible promoters: a systematic approach to novel pathway-specific reporter assays for antibacterial drug discovery. Genome Res (2004) 0.95
A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes. J Bacteriol (1995) 0.93
X-ray crystal structure of Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase II (mtKasB). J Mol Biol (2006) 0.91
A missense mutation in the fabB (beta-ketoacyl-acyl carrier protein synthase I) gene confers tiolactomycin resistance to Escherichia coli. Antimicrob Agents Chemother (2002) 0.91
Functional analysis of putative beta-ketoacyl:acyl carrier protein synthase and acyltransferase active site motifs in a type II polyketide synthase of Streptomyces glaucescens. J Bacteriol (1995) 0.90
Soybeans grown in the Chernobyl area produce fertile seeds that have increased heavy metal resistance and modified carbon metabolism. PLoS One (2012) 0.88
Structure of the human beta-ketoacyl [ACP] synthase from the mitochondrial type II fatty acid synthase. Protein Sci (2007) 0.87
Analysis of type II polyketide beta-ketoacyl synthase specificity in Streptomyces coelicolor A3(2) by trans complementation of actinorhodin synthase mutants. J Bacteriol (1994) 0.86
Increased unsaturated fatty acid production associated with a suppressor of the fabA6(Ts) mutation in Escherichia coli. J Bacteriol (1996) 0.82
Bacterial fatty acid metabolism in modern antibiotic discovery. Biochim Biophys Acta (2016) 0.77
Inactivation of the polyketide synthase, 6-methylsalicylic acid synthase, by the specific modification of Cys-204 of the beta-ketoacyl synthase by the fungal mycotoxin cerulenin. Biochem J (1998) 0.77
Structure of 3-oxoacyl-(acyl-carrier protein) synthase II from Thermus thermophilus HB8. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.76
UV-B Radiation Stress Causes Alterations in Whole Cell Protein Profile and Expression of Certain Genes in the Rice Phyllospheric Bacterium Enterobacter cloacae. Front Microbiol (2016) 0.75
Reaction mechanism of recombinant 3-oxoacyl-(acyl-carrier-protein) synthase III from Cuphea wrightii embryo, a fatty acid synthase type II condensing enzyme. Biochem J (2000) 0.75
N-acylated derivatives of sulfamethoxazole block Chlamydia fatty acid synthesis and interact with FabF. Antimicrob Agents Chemother (2017) 0.75
The X-ray crystal structure of beta-ketoacyl [acyl carrier protein] synthase I. FEBS Lett (1999) 1.31
Primary structure of a cerulenin-binding beta-ketoacyl-[acyl carrier protein] synthase from barley chloroplasts. Proc Natl Acad Sci U S A (1991) 1.27
Structures of beta-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery. Structure (2001) 1.06
Chromosomal location in wheat of the genes coding for the acyl carrier proteins I and III. Theor Appl Genet (1991) 1.01
A mathematical model of the hemoglobin-oxygen dissociation curve of human blood and of the oxygen partial pressure as a function of temperature. Clin Chem (1984) 0.96
The barley genes Acl1 and Acl3 encoding acyl carrier proteins I and III are located on different chromosomes. Mol Gen Genet (1991) 0.95
The fabJ-encoded beta-ketoacyl-[acyl carrier protein] synthase IV from Escherichia coli is sensitive to cerulenin and specific for short-chain substrates. Proc Natl Acad Sci U S A (1994) 0.95
beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket. Biochemistry (2001) 0.93
Biosynthesis of the beta-diketones of barley spike epicuticular wax. Arch Biochem Biophys (1976) 0.90
The oxygen status algorithm: a computer program for calculating and displaying pH and blood gas data. Scand J Clin Lab Invest Suppl (1990) 0.88
Ultrastructure and origin of epicuticular wax tubes. J Ultrastruct Res (1974) 0.88
Donnan effect or protein interference in ionised calcium measurements? Ann Clin Biochem (1983) 0.85
Acyl carrier protein (ACP) inhibition and other differences between beta-ketoacyl synthase (KAS) I and II. Biochem Soc Trans (2000) 0.84
Apparent in vivo retroconversion of dietary arachidonic to linoleic acid in essential fatty acid-deficient rats. Biochim Biophys Acta (1986) 0.81
Biosynthesis of beta-diketones and hydrocarbons in barley spike epicuticular wax. Arch Biochem Biophys (1978) 0.78
Role of cer-cqu in epicuticular wax biosynthesis. Biochem Soc Trans (1986) 0.77
The physico-chemical basis of leaf wettability in wheat. Planta (1973) 0.77
When is the male plastome eliminated? Nature (1970) 0.75
The TANH-equation modified for the hemoglobin, oxygen, and carbon monoxide equilibrium. Scand J Clin Lab Invest Suppl (1993) 0.75