Published in Biol Psychiatry on January 01, 1986
Realistic expectations of prepulse inhibition in translational models for schizophrenia research. Psychopharmacology (Berl) (2008) 2.64
Heritable differences in the dopaminergic regulation of sensorimotor gating. II. Temporal, pharmacologic and generational analyses of apomorphine effects on prepulse inhibition. Psychopharmacology (Berl) (2003) 1.20
Behavioral and neurochemical characterization of mice deficient in the phosphodiesterase-4B (PDE4B) enzyme. Psychopharmacology (Berl) (2007) 1.08
Strain differences in the gating-disruptive effects of apomorphine: relationship to gene expression in nucleus accumbens signaling pathways. Biol Psychiatry (2008) 1.04
Heritable differences in the dopaminergic regulation of behavior in rats: relationship to D2-like receptor G-protein function. Neuropsychopharmacology (2006) 1.01
F15063, a compound with D2/D3 antagonist, 5-HT 1A agonist and D4 partial agonist properties. II. Activity in models of positive symptoms of schizophrenia. Br J Pharmacol (2007) 0.99
A novel rat strain with enhanced sensitivity to the effects of dopamine agonists on startle gating. Pharmacol Biochem Behav (2007) 0.97
Separable noradrenergic and dopaminergic regulation of prepulse inhibition in rats: implications for predictive validity and Tourette Syndrome. Psychopharmacology (Berl) (2006) 0.96
Heritable strain differences in sensitivity to the startle gating-disruptive effects of D2 but not D3 receptor stimulation. Behav Pharmacol (2008) 0.95
Using prepulse inhibition to detect functional D3 receptor antagonism: effects of WC10 and WC44. Pharmacol Biochem Behav (2009) 0.93
Behavioral and neurobiological changes in C57BL/6 mouse exposed to cuprizone: effects of antipsychotics. Front Behav Neurosci (2010) 0.92
Strain differences in the disruption of prepulse inhibition of startle after systemic and intra-accumbens amphetamine administration. Pharmacol Biochem Behav (2007) 0.92
Convergence and divergence in the neurochemical regulation of prepulse inhibition of startle and N40 suppression in rats. Neuropsychopharmacology (2006) 0.91
The glycine transporter-1 inhibitor SSR103800 displays a selective and specific antipsychotic-like profile in normal and transgenic mice. Neuropsychopharmacology (2010) 0.91
The effect of 'two hit' neonatal and young-adult stress on dopaminergic modulation of prepulse inhibition and dopamine receptor density. Br J Pharmacol (2009) 0.91
Dendritic distributions of dopamine D1 receptors in the rat nucleus accumbens are synergistically affected by startle-evoking auditory stimulation and apomorphine. Neuroscience (2007) 0.90
Age-associated improvements in cross-modal prepulse inhibition in mice. Behav Neurosci (2010) 0.89
Ventral striatal noradrenergic mechanisms contribute to sensorimotor gating deficits induced by amphetamine. Neuropsychopharmacology (2010) 0.86
Reduced startle gating after D1 blockade: effects of concurrent D2 blockade. Pharmacol Biochem Behav (2005) 0.85
Neural basis for a heritable phenotype: differences in the effects of apomorphine on startle gating and ventral pallidal GABA efflux in male Sprague-Dawley and Long-Evans rats. Psychopharmacology (Berl) (2009) 0.84
Preferential relocation of the N-methyl-D-aspartate receptor NR1 subunit in nucleus accumbens neurons that contain dopamine D1 receptors in rats showing an apomorphine-induced sensorimotor gating deficit. Neuroscience (2008) 0.82
Effects of acute treatment with antidepressant drugs on sensorimotor gating deficits in rats. Psychopharmacology (Berl) (2004) 0.81
Cannabidiol effects in the prepulse inhibition disruption induced by amphetamine. Psychopharmacology (Berl) (2015) 0.81
Activation of a nitric-oxide-sensitive cAMP pathway with phencyclidine: elevated hippocampal cAMP levels are temporally associated with deficits in prepulse inhibition. Psychopharmacology (Berl) (2004) 0.81
Probing the molecular basis for an inherited sensitivity to the startle-gating disruptive effects of apomorphine in rats. Psychopharmacology (Berl) (2011) 0.80
The effect of pregabalin on sensorimotor gating in 'low' gating humans and mice. Neuropharmacology (2012) 0.80
Habituation of acoustic startle is disrupted by psychotomimetic drugs: differential dependence on dopaminergic and nitric oxide modulatory mechanisms. Psychopharmacology (Berl) (2004) 0.80
Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder. PLoS One (2015) 0.78
Projections from ventral hippocampus to medial prefrontal cortex but not nucleus accumbens remain functional after fornix lesions in rats. Neuroscience (2010) 0.78
Reduction in phencyclidine induced sensorimotor gating deficits in the rat following increased system xc⁻ activity in the medial prefrontal cortex. Psychopharmacology (Berl) (2012) 0.78
A novel mouse Chr5 locus Diht controls dopamine-induced hypothermia. Mamm Genome (2004) 0.77
Investigating the underlying mechanisms of aberrant behaviors in bipolar disorder from patients to models: Rodent and human studies. Neurosci Biobehav Rev (2015) 0.77
T-817MA, a novel neurotrophic compound, ameliorates phencyclidine-induced disruption of sensorimotor gating. Psychopharmacology (Berl) (2008) 0.77
Mice repeatedly exposed to Group-A β-Haemolytic Streptococcus show perseverative behaviors, impaired sensorimotor gating, and immune activation in rostral diencephalon. Sci Rep (2015) 0.77
Effects of haloperidol and clozapine on sensorimotor gating deficits induced by 5-hydroxytryptamine depletion in the brain. Br J Pharmacol (2006) 0.76
Clerodendrum inerme Leaf Extract Alleviates Animal Behaviors, Hyperlocomotion, and Prepulse Inhibition Disruptions, Mimicking Tourette Syndrome and Schizophrenia. Evid Based Complement Alternat Med (2012) 0.75
Relationship between Toxoplasma gondii seropositivity and acoustic startle response in an inner-city population. Brain Behav Immun (2016) 0.75
Neurocognitive deficits and functional outcome in schizophrenia: are we measuring the "right stuff"? Schizophr Bull (2000) 9.62
Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology (Berl) (2001) 5.67
Transition from moderate to excessive drug intake: change in hedonic set point. Science (1998) 5.66
Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review. Psychopharmacology (Berl) (2001) 4.52
Sensorimotor gating and schizophrenia. Human and animal model studies. Arch Gen Psychiatry (1990) 4.08
Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges. Psychopharmacology (Berl) (2001) 4.03
Modulation of cocaine self-administration in the rat through D-3 dopamine receptors. Science (1993) 3.67
Neural mechanisms underlying nicotine addiction: acute positive reinforcement and withdrawal. Nicotine Tob Res (2000) 3.33
Dramatic decreases in brain reward function during nicotine withdrawal. Nature (1998) 3.21
Excessive ethanol drinking following a history of dependence: animal model of allostasis. Neuropsychopharmacology (2000) 3.15
Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development. Neuron (1998) 3.08
Suppression of psychoactive effects of cocaine by active immunization. Nature (1995) 3.05
Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress. Nat Genet (2000) 3.04
Animal models of deficient sensorimotor gating: what we know, what we think we know, and what we hope to know soon. Behav Pharmacol (2000) 3.03
Neurobiological similarities in depression and drug dependence: a self-medication hypothesis. Neuropsychopharmacology (1998) 2.96
Drug dependence: stress and dysregulation of brain reward pathways. Drug Alcohol Depend (1998) 2.94
Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: genetic and motivational determinants. J Pharmacol Exp Ther (1993) 2.79
Gating and habituation of the startle reflex in schizophrenic patients. Arch Gen Psychiatry (1992) 2.72
Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis. J Neurosci (1995) 2.70
Effects of moderate alcohol consumption on the central nervous system. Alcohol Clin Exp Res (1998) 2.60
Intra-amygdala muscimol decreases operant ethanol self-administration in dependent rats. Alcohol Clin Exp Res (1996) 2.51
Activation of corticotropin-releasing factor in the limbic system during cannabinoid withdrawal. Science (1997) 2.50
Postcocaine anhedonia. An animal model of cocaine withdrawal. Neuropsychopharmacology (1991) 2.41
Animal models of drug craving. Psychopharmacology (Berl) (1993) 2.32
Microinjection of a corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal. Brain Res (1993) 2.27
Cocaine vaccines: antibody protection against relapse in a rat model. Proc Natl Acad Sci U S A (2000) 2.16
Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats. Psychopharmacology (Berl) (1984) 2.13
Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses. Cell (1994) 2.05
Persistent increase in the motivation to take heroin in rats with a history of drug escalation. Neuropsychopharmacology (2000) 2.04
CRF antagonist reverses the "anxiogenic" response to ethanol withdrawal in the rat. Psychopharmacology (Berl) (1991) 2.04
Long-lasting increase in the set point for cocaine self-administration after escalation in rats. Psychopharmacology (Berl) (1999) 2.01
Decreased brain reward produced by ethanol withdrawal. Proc Natl Acad Sci U S A (1995) 2.00
Construct validity of a self-stimulation threshold paradigm: effects of reward and performance manipulations. Physiol Behav (1992) 1.96
Ethanol self-administration restores withdrawal-associated deficiencies in accumbal dopamine and 5-hydroxytryptamine release in dependent rats. J Neurosci (1996) 1.95
GABAA receptor antagonism in the extended amygdala decreases ethanol self-administration in rats. Eur J Pharmacol (1995) 1.93
Appetite-suppressing effects of urocortin, a CRF-related neuropeptide. Science (1996) 1.91
Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients. Arch Gen Psychiatry (1994) 1.90
Attitudes toward psychiatry as a prospective career among students entering medical school. Am J Psychiatry (1999) 1.88
Corticotropin releasing factor produces behavioural activation in rats. Nature (1982) 1.82
Dopaminergic stimulation disrupts sensorimotor gating in the rat. Psychopharmacology (Berl) (1988) 1.80
A second-generation vaccine protects against the psychoactive effects of cocaine. Proc Natl Acad Sci U S A (2001) 1.78
Functional interaction between opioid and cannabinoid receptors in drug self-administration. J Neurosci (2001) 1.78
Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach. Mol Psychiatry (2004) 1.76
Heroin and cocaine intravenous self-administration in rats: mediation by separate neural systems. Psychopharmacology (Berl) (1982) 1.76
Dopamine D4 receptor-knock-out mice exhibit reduced exploration of novel stimuli. J Neurosci (1999) 1.69
Identification of blood biomarkers for psychosis using convergent functional genomics. Mol Psychiatry (2009) 1.68
mu-Opioid receptor knockout mice do not self-administer alcohol. J Pharmacol Exp Ther (2000) 1.67
Performance norms for a rhesus monkey neuropsychological testing battery: acquisition and long-term performance. Brain Res Cogn Brain Res (1999) 1.66
Overproduction of corticotropin-releasing factor in transgenic mice: a genetic model of anxiogenic behavior. J Neurosci (1994) 1.65
Impaired prepulse inhibition of acoustic and tactile startle response in patients with Huntington's disease. J Neurol Neurosurg Psychiatry (1995) 1.64
Corticotropin-releasing factor and neuropeptide Y: role in emotional integration. Trends Neurosci (1994) 1.61
Modulation of the startle response and startle laterality in relatives of schizophrenic patients and in subjects with schizotypal personality disorder: evidence of inhibitory deficits. Am J Psychiatry (2000) 1.60
Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration. Brain Res (1992) 1.60
Effects of the dopamine D-1 antagonist SCH 23390 microinjected into the accumbens, amygdala or striatum on cocaine self-administration in the rat. Brain Res (1995) 1.59
Blockade of nicotine self-administration with nicotinic antagonists in rats. Pharmacol Biochem Behav (1999) 1.58
Intraventricular corticotropin-releasing factor enhances behavioral effects of novelty. Life Sci (1982) 1.57
Reward and somatic changes during precipitated nicotine withdrawal in rats: centrally and peripherally mediated effects. J Pharmacol Exp Ther (2000) 1.56
Multivariate assessment of locomotor behavior: pharmacological and behavioral analyses. Pharmacol Biochem Behav (1986) 1.56
Towards understanding the schizophrenia code: an expanded convergent functional genomics approach. Am J Med Genet B Neuropsychiatr Genet (2007) 1.55
Sensorimotor gating deficits in bipolar disorder patients with acute psychotic mania. Biol Psychiatry (2001) 1.55
Impact of prepulse characteristics on the detection of sensorimotor gating deficits in schizophrenia. Schizophr Res (2001) 1.54
Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists. J Neurosci (2001) 1.54
Prefrontal, parietal, and temporal cortex networks underlie decision-making in the presence of uncertainty. Neuroimage (2001) 1.53
Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia. Schizophr Bull (1998) 1.53
A preliminary assessment of sensorimotor gating in patients with obsessive compulsive disorder. Biol Psychiatry (1993) 1.52
Cocaine- but not food-seeking behavior is reinstated by stress after extinction. Psychopharmacology (Berl) (1997) 1.50
Modulation of social memory in male rats by neurohypophyseal peptides. Psychopharmacology (Berl) (1987) 1.49
Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens. Pharmacol Biochem Behav (1980) 1.48
Neonatal excitotoxic hippocampal damage in rats causes post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine. Psychopharmacology (Berl) (1995) 1.48
Effects of dopamine D-1 and D-2 antagonists on cocaine self-administration under different schedules of reinforcement in the rat. J Pharmacol Exp Ther (1994) 1.47
Corticotropin-releasing factor antagonist attenuates the "anxiogenic-like" effect in the defensive burying paradigm but not in the elevated plus-maze following chronic cocaine in rats. Psychopharmacology (Berl) (1999) 1.46
Operant self-administration of sweetened versus unsweetened ethanol: effects on blood alcohol levels. Alcohol Clin Exp Res (1999) 1.45
Genetic differences in response to novelty and spatial memory using a two-trial recognition task in mice. Neurobiol Learn Mem (2000) 1.44
Startle response models of sensorimotor gating and habituation deficits in schizophrenia. Brain Res Bull (1990) 1.44
Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides. Science (1993) 1.43
Anxiolytic-like action of neuropeptide Y: mediation by Y1 receptors in amygdala, and dissociation from food intake effects. Neuropsychopharmacology (1993) 1.43
Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats. Pharmacol Biochem Behav (1982) 1.41
Startle habituation and sensorimotor gating in schizophrenia and related animal models. Schizophr Bull (1987) 1.41
Tactile prepuff inhibition of startle in children with Tourette's syndrome: in search of an "fMRI-friendly" startle paradigm. Biol Psychiatry (2001) 1.39
Dopamine and depression: circuitous logic? Biol Psychiatry (1993) 1.39
Corticotropin-releasing factor potentiates acoustic startle in rats: blockade by chlordiazepoxide. Psychopharmacology (Berl) (1986) 1.38
Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbens. Psychopharmacology (Berl) (1992) 1.38
Poor P50 suppression among schizophrenia patients and their first-degree biological relatives. Am J Psychiatry (1998) 1.38
A systems model of altered consciousness: integrating natural and drug-induced psychoses. Brain Res Bull (2001) 1.36