Published in Biochem Pharmacol on April 15, 1986
Pharmacogenetics of human carbonyl reductase 1 (CBR1) in livers from black and white donors. Drug Metab Dispos (2008) 1.12
Specificity of human aldo-keto reductases, NAD(P)H:quinone oxidoreductase, and carbonyl reductases to redox-cycle polycyclic aromatic hydrocarbon diones and 4-hydroxyequilenin-o-quinone. Chem Res Toxicol (2011) 1.00
Functional characterization of the promoter of human carbonyl reductase 1 (CBR1). Role of XRE elements in mediating the induction of CBR1 by ligands of the aryl hydrocarbon receptor. Mol Pharmacol (2007) 0.98
Structural basis for substrate specificity in human monomeric carbonyl reductases. PLoS One (2009) 0.92
A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity. Drug Metab Dispos (2007) 0.92
Higher activity of polymorphic NAD(P)H:quinone oxidoreductase in liver cytosols from blacks compared to whites. Toxicol Lett (2006) 0.89
Distinct genes related to drug response identified in ER positive and ER negative breast cancer cell lines. PLoS One (2012) 0.83
Mass spectrometric peptide mapping analysis and structural characterization of dihydrodiol dehydrogenase isoenzymes. Environ Health Perspect (1990) 0.79
Induction of carbonyl reductase 1 (CBR1) expression in human lung tissues and lung cancer cells by the cigarette smoke constituent benzo[a]pyrene. Toxicol Lett (2012) 0.79
Mutation of tyrosine-194 and lysine-198 in the catalytic site of pig 3alpha/beta,20beta-hydroxysteroid dehydrogenase. Biochem J (1998) 0.78
Carbonyl Reductase 3 (CBR3) Mediates 9-cis-Retinoic Acid-Induced Cytostatis and is a Potential Prognostic Marker for Oral Malignancy. Open Dent J (2008) 0.77
The role of cytochromes p450 and aldo-keto reductases in prognosis of breast carcinoma patients. Medicine (Baltimore) (2014) 0.77
Characterization of the UDP-glucuronosyltransferase isoenzyme expressed in rat ovary and its regulation by gonadotropins. Biochem J (1998) 0.75
Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds. Xenobiotica (1973) 2.96
The aldo-keto reductase superfamily. cDNAs and deduced amino acid sequences of human aldehyde and aldose reductases. J Biol Chem (1989) 2.59
First pass annotation of promoters on human chromosome 22. Genome Res (2001) 1.99
Differences in the catalytic efficiencies of allelic variants of glutathione transferase P1-1 towards carcinogenic diol epoxides of polycyclic aromatic hydrocarbons. Carcinogenesis (1998) 1.88
A multiplex polymerase chain reaction protocol for the simultaneous analysis of the glutathione S-transferase GSTM1 and GSTT1 polymorphisms. Anal Biochem (1996) 1.78
Studies on the biosynthesis of microsomal membrane proteins. Site of synthesis and mode of insertion of cytochrome b5, cytochrome b5 reductase, cytochrome P-450 reductase and epoxide hydrolase. Eur J Biochem (1982) 1.78
Granulocyte-macrophage-colony-stimulating factor enhances immune responses to melanoma-associated peptides in vivo. Int J Cancer (1996) 1.76
Immunoselection in vivo: independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma. Int J Cancer (1997) 1.72
Purification and properties of an NADPH-dependent carbonyl reductase from human brain. Relationship to prostaglandin 9-ketoreductase and xenobiotic ketone reductase. J Biol Chem (1981) 1.72
Inverse relationship of melanocyte differentiation antigen expression in melanoma tissues and CD8+ cytotoxic-T-cell responses: evidence for immunoselection of antigen-loss variants in vivo. Int J Cancer (1996) 1.39
Studies on the subunit composition of rat liver glutathione S-transferases. J Biol Chem (1983) 1.38
Stable expression of rat cytochrome P-450IIB1 cDNA in Chinese hamster cells (V79) and metabolic activation of aflatoxin B1. Proc Natl Acad Sci U S A (1988) 1.37
Chronic recurrent multifocal osteomyelitis in children. Pediatr Infect Dis J (1999) 1.34
Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility. Recent Results Cancer Res (1998) 1.33
Unrepaired fjord region polycyclic aromatic hydrocarbon-DNA adducts in ras codon 61 mutational hot spots. Cancer Res (2000) 1.29
Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors. Biochemistry (1971) 1.22
Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase. J Biol Chem (1996) 1.22
Purification and characterization of human-brain aldose reductase. Eur J Biochem (1982) 1.22
Characterization, localization and regulation of a novel phenobarbital-inducible form of cytochrome P450, compared with three further P450-isoenzymes, NADPH P450-reductase, glutathione transferases and microsomal epoxide hydrolase. Carcinogenesis (1984) 1.20
Rat liver cytoplasmic dihydrodiol dehydrogenase. Purification to apparent homogeneity and properties. J Biol Chem (1980) 1.19
DNA repair activity of 8-oxoguanine DNA glycosylase 1 (OGG1) in human lymphocytes is not dependent on genetic polymorphism Ser326/Cys326. Mutat Res (2001) 1.19
Induction of the peroxisome proliferator activated receptor by fenofibrate in rat liver. FEBS Lett (1992) 1.18
Conversion of naphthalene to trans-naphthalene dihydrodiol: evidence for the presence of a coupled aryl monooxygenase-epoxide hydrase system in hepatic microsomes. Biochem Biophys Res Commun (1972) 1.18
Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction. Drug Metab Rev (2000) 1.18
Nerve growth factor induces volume increase and enhances tyrosine hydroxylase synthesis in chemically axotomized sympathetic ganglia of newborn rats. Proc Natl Acad Sci U S A (1975) 1.17
Contact inhibition of growth of human diploid fibroblasts by immobilized plasma membrane glycoproteins. J Cell Biol (1986) 1.17
Interspecies differences in cancer susceptibility and toxicity. Drug Metab Rev (1999) 1.17
Structure of Aspergillus niger epoxide hydrolase at 1.8 A resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases. Structure (2000) 1.16
Cytolytic T cell reactivity against melanoma-associated differentiation antigens in peripheral blood of melanoma patients and healthy individuals. Melanoma Res (1996) 1.16
Stable expression of human cytochrome P450 1B1 in V79 Chinese hamster cells and metabolically catalyzed DNA adduct formation of dibenzo[a,l]pyrene. Chem Res Toxicol (1998) 1.16
Prophylaxis and reversal of ifosfamide encephalopathy with methylene-blue. Lancet (1994) 1.15
Purification and properties of NADPH-dependent aldehyde reductase from human liver. J Biol Chem (1977) 1.15
Purification and specificity of a human microsomal epoxide hydratase. Biochem J (1974) 1.14
Multiple forms of cytochrome P-450 related to forms induced marginally by phenobarbital. Differences in structure and in the metabolism of alkoxyresorufins. Biochem J (1986) 1.13
Gene evolution of epoxide hydrolases and recommended nomenclature. DNA Cell Biol (1995) 1.13
Visualization of a covalent intermediate between microsomal epoxide hydrolase, but not cholesterol epoxide hydrolase, and their substrates. Eur J Biochem (1997) 1.12
Expression of pyruvate kinase M2 in preneoplastic hepatic foci of N-nitrosomorpholine-treated rats. Virchows Arch (1999) 1.12
Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites. Carcinogenesis (1999) 1.11
Differential regulation of hepatic glutathione transferase and glutathione peroxidase activities in the rat. Biochem Pharmacol (1985) 1.11
Mutagenicity of phenanthrene and phenanthrene K-region derivatives. Mutat Res (1979) 1.10
Chiral effects in the induction of drug-metabolizing enzymes using synthetic atropisomers of polychlorinated biphenyls (PCBs). Biochem Pharmacol (1989) 1.10
Polymorphisms in P450 CYP1B1 affect the conversion of estradiol to the potentially carcinogenic metabolite 4-hydroxyestradiol. Pharmacogenetics (2000) 1.10
Mutation of ornithine transcarbamylase (H136R) in a girl with severe intermittent orotic aciduria but normal enzyme activity. J Inherit Metab Dis (1997) 1.08
p16INK4 mediates contact-inhibition of growth. Oncogene (1999) 1.06
Multiple activation pathways of benzene leading to products with varying genotoxic characteristics. Environ Health Perspect (1989) 1.06
Glutathione conjugation of bay- and fjord-region diol epoxides of polycyclic aromatic hydrocarbons by glutathione transferases M1-1 and P1-1. Chem Res Toxicol (1997) 1.05
The identification, solubilization, and characterization of microsome-associated glutathione S-transferases. J Biol Chem (1979) 1.04
Identification of human cytochromes P-450 analogous to forms induced by phenobarbital and 3-methylcholanthrene in the rat. Biochem J (1985) 1.03
Effect of diabetes and starvation on the activity of rat liver epoxide hydrolases, glutathione S-transferases and peroxisomal beta-oxidation. Biochem Pharmacol (1989) 1.03
A reconstituted microsomal enzyme system that converts naphthalene to trans-1,2-dihydroxy-1,2-dihydronaphthalene via naphthalene-1,2-oxide: presence of epoxide hydrase in cytochrome P-450 and P-448 fractions. Arch Biochem Biophys (1972) 1.03
Kinetics of carbonyl reductase from human brain. Biochem J (1987) 1.01
Xenobiotic metabolizing enzymes are not restricted to parenchymal cells in rat liver. Mol Pharmacol (1987) 1.01
Human carbonyl and aldose reductases: new catalytic functions in tetrahydrobiopterin biosynthesis. Biochem Biophys Res Commun (1991) 1.01
N-Acetylglutamate synthetase deficiency responding to carbamylglutamate. J Inherit Metab Dis (1997) 1.01
Isolation and characterization of a 60-70-kD plasma membrane glycoprotein involved in the contact-dependent inhibition of growth. J Cell Biol (1990) 1.00
A method for the cryopreservation of liver parenchymal cells for studies of xenobiotics. Cryobiology (1993) 1.00
Cytosolic and microsomal epoxide hydrolases are immunologically distinguishable from each other in the rat and mouse. J Biol Chem (1981) 1.00
Orientation, structure, wet-spinning, and molecular basis for supercontraction of spider dragline silk. Int J Biol Macromol (1999) 1.00
Activation of N-acetoxy- and N-hydroxy-2-acetylaminofluorene to mutagenic and cytotoxic metabolites by V79 Chinese hamster cells. Mutat Res (1985) 1.00
Cloning and molecular characterization of a soluble epoxide hydrolase from Aspergillus niger that is related to mammalian microsomal epoxide hydrolase. Biochem J (1999) 1.00
Purification of rat liver epoxide hydratase to apparent homogeneity. FEBS Lett (1975) 0.99
Training-overtraining: performance, and hormone levels, after a defined increase in training volume versus intensity in experienced middle- and long-distance runners. Br J Sports Med (1992) 0.99
Isolation of a putative hydroxyacyl enzyme intermediate of an epoxide hydrolase. Biochem Biophys Res Commun (1994) 0.98
Solubilization, purification, and properties of a hepatic epoxide hydrase. Biochim Biophys Acta (1971) 0.97
Regulation and expression of four cytochrome P-450 isoenzymes, NADPH-cytochrome P-450 reductase, the glutathione transferases B and C and microsomal epoxide hydrolase in preneoplastic and neoplastic lesions in rat liver. Carcinogenesis (1985) 0.97
Identity of dihydrodiol dehydrogenase and 3 alpha-hydroxysteroid dehydrogenase in rat but not in rabbit liver cytosol. FEBS Lett (1984) 0.97
Glutathione S-transferase A1-1-catalysed conjugation of bay and fjord region diol epoxides or polycyclic aromatic hydrocarbons with glutathione. Carcinogenesis (1996) 0.97
Identification of the reactive cysteine residue (Cys227) in human carbonyl reductase. Eur J Biochem (1999) 0.97
In vivo modulated N-acyl side chain of N-acetylneuraminic acid modulates the cell contact-dependent inhibition of growth. FEBS Lett (1996) 0.96
Inactivation of a diol epoxide by dihydrodiol dehydrogenase but not by two epoxide hydrolases. Science (1982) 0.96
p53-dependent cell cycle arrest induced by N-acetyl-L-leucinyl-L-leucinyl-L-norleucinal in platelet-derived growth factor-stimulated human fibroblasts. Proc Natl Acad Sci U S A (1996) 0.96
Differences in the mechanisms of growth control in contact-inhibited and serum-deprived human fibroblasts. Oncogene (1997) 0.96
Catalytic triad of microsomal epoxide hydrolase: replacement of Glu404 with Asp leads to a strongly increased turnover rate. Biochem J (1999) 0.96
Human brain aldehyde reductases: relationship to succinic semialdehyde reductase and aldose reductase. J Neurochem (1980) 0.96
Isolation of a high spin form of cytochrome P-450 induced in rat liver by 3-methylcholanthrene. Biochem Biophys Res Commun (1983) 0.96
Latency of epoxide hydratase and its relationship to that of UDPglucuronyltransferase. Biochim Biophys Acta (1976) 0.96
Involvement of plasma membrane glycoproteins in the contact-dependent inhibition of growth of human fibroblasts. Exp Cell Res (1985) 0.95
Kinetics of chlormethiazole in patients with alcohol withdrawal manifestations. Clin Pharmacol Ther (1978) 0.95
Differential modulation of CYP2E1 activity by cAMP-dependent protein kinase upon Ser129 replacement. Exp Cell Res (1998) 0.95
Stereoselective activation of dibenzo[a,l]pyrene to (-)-anti (11R,12S,13S,14R)- and (+)-syn(11S,12R,13S,14R)-11,12-diol-13,14-epoxides which bind extensively to deoxyadenosine residues of DNA in the human mammary carcinoma cell line MCF-7. Carcinogenesis (1995) 0.95
The apparent ubiquity of epoxide hydratase in rat organs. Biochem Pharmacol (1977) 0.95
TCDD deregulates contact inhibition in rat liver oval cells via Ah receptor, JunD and cyclin A. Oncogene (2007) 0.94
Reduction of benzo(a)pyrene mutagenicity by dihydrodiol dehydrogenase. Nature (1979) 0.94
Aldose and aldehyde reductase exhibit isocorticosteroid reductase activity. Eur J Biochem (1983) 0.94
A novel two-nucleotide deletion in the ornithine transcarbamylase gene causing fatal hyperammonia in early pregnancy. Hepatology (1996) 0.93
Applications of stable V79-derived cell lines expressing rat cytochromes P4501A1, 1A2, and 2B1. Xenobiotica (1992) 0.93
Mutagenicity of glutathione and cysteine in the Ames test. Science (1983) 0.93
RNAi knock-down mice: an emerging technology for post-genomic functional genetics. Cytogenet Genome Res (2004) 0.93
Specificity of human, rat and mouse skin epoxide hydratase towards K-region epoxides of polycyclic hydrocarbons. Biochem Pharmacol (1978) 0.92
Carbohydrate metabolism in human renal clear cell carcinomas. Lab Invest (1992) 0.92
Isoenzyme-specific phosphorylation of cytochromes P-450 and other drug metabolizing enzymes. Biochem Biophys Res Commun (1987) 0.92
Glutathione, glutathione S-transferase alpha and pi, and aldehyde dehydrogenase content in relationship to drug resistance in ovarian cancer. Gynecol Oncol (1997) 0.91
Phosphorylation of cytochromes P450: first discovery of a posttranslational modification of a drug-metabolizing enzyme. Biochem Biophys Res Commun (2005) 0.91
A rapid assay for epoxide hydratase activity with benzo (a)pyrene 4,5-(K-region)-oxide as substrate. Anal Biochem (1976) 0.91
Density-dependent regulation of cell growth by contactinhibin and the contactinhibin receptor. Curr Biol (1995) 0.91
Multi-step metabolic activation of benzene. Effect of superoxide dismutase on covalent binding to microsomal macromolecules, and identification of glutathione conjugates using high pressure liquid chromatography and field desorption mass spectrometry. Chem Biol Interact (1980) 0.91