Published in DNA on October 01, 1986
A DNA sequence of 15 base pairs is sufficient to mediate both glucocorticoid and progesterone induction of gene expression. Proc Natl Acad Sci U S A (1987) 3.07
A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor. Nucleic Acids Res (1988) 2.67
Specific glucocorticoid receptor binding to DNA reconstituted in a nucleosome. EMBO J (1988) 2.66
The estrogen-responsive element as an inducible enhancer: DNA sequence requirements and conversion to a glucocorticoid-responsive element. EMBO J (1987) 2.53
Cooperative binding of estrogen receptor to imperfect estrogen-responsive DNA elements correlates with their synergistic hormone-dependent enhancer activity. EMBO J (1989) 1.82
Type 1 plasminogen activator inhibitor gene: functional analysis and glucocorticoid regulation of its promoter. Proc Natl Acad Sci U S A (1988) 1.64
Specific binding of estrogen receptor to the estrogen response element. Mol Cell Biol (1989) 1.61
Enhancer and promoter elements directing activation and glucocorticoid repression of the alpha 1-fetoprotein gene in hepatocytes. Mol Cell Biol (1988) 1.30
The cell-specific elastase I enhancer comprises two domains. Mol Cell Biol (1988) 1.26
Tissue-specific and steroid-dependent interaction of transcription factors with the oestrogen-inducible apoVLDL II promoter in vivo. EMBO J (1988) 1.17
Tissue specific sequence motifs in the enhancer of the leukaemogenic mouse retrovirus SL3-3. Nucleic Acids Res (1988) 1.10
A progesterone responsive element maps to the far upstream steroid dependent DNase hypersensitive site of chicken lysozyme chromatin. EMBO J (1988) 1.08
Expression of human estrogen receptor mutants in Xenopus oocytes: correlation between transcriptional activity and ability to form protein-DNA complexes. EMBO J (1988) 1.03
Estrogen and progesterone receptor-binding sites on the chicken vitellogenin II gene: synergism of steroid hormone action. Mol Cell Biol (1988) 0.94
Functional analysis of the long terminal repeats of Drosophila 1731 retrotransposon: promoter function and steroid regulation. Nucleic Acids Res (1989) 0.92
The human estrogen receptor can regulate exogenous but not endogenous vitellogenin gene promoters in a Xenopus cell line. Nucleic Acids Res (1988) 0.90
Synergistic action of glucocorticoid and estradiol responsive elements. Proc Natl Acad Sci U S A (1988) 0.89
Evolutionary history and functional characterization of androgen receptor genes in jawed vertebrates. Endocrinology (2009) 0.89
The p27-Skp2 axis mediates glucocorticoid-induced cell cycle arrest in T-lymphoma cells. Cell Cycle (2013) 0.86
Structure and nucleotide sequence of the rat intestinal vitamin D-dependent calcium binding protein gene. Proc Natl Acad Sci U S A (1988) 0.81
Hormonal induction of transfected genes depends on DNA topology. Mol Cell Biol (1990) 0.81
Isolation and functional analysis of chicken 90-kDa heat shock protein gene promoter. Nucleic Acids Res (1989) 0.76
The nuclear receptor superfamily: the second decade. Cell (1995) 24.99
Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene. Nature (1984) 7.57
The glucocorticoid receptor binds to defined nucleotide sequences near the promoter of mouse mammary tumour virus. Nature (1983) 5.76
Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro. Proc Natl Acad Sci U S A (1988) 4.33
The hormone regulatory element of mouse mammary tumour virus mediates progesterone induction. EMBO J (1986) 4.04
Cloning of the DNA-binding subunit of human nuclear factor kappa B: the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor alpha. Proc Natl Acad Sci U S A (1991) 3.80
Nucleosome positioning modulates accessibility of regulatory proteins to the mouse mammary tumor virus promoter. Cell (1990) 3.75
Glucocorticoid and progesterone receptors bind to the same sites in two hormonally regulated promoters. Nature (1985) 3.45
NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition. Mol Cell Biol (1999) 3.42
A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proc Natl Acad Sci U S A (1994) 3.33
Glucocorticoid responsiveness of the transcriptional enhancer of Moloney murine sarcoma virus. Cell (1986) 3.31
Sp1-mediated transcriptional activation is repressed by Sp3. EMBO J (1994) 3.27
Tissue-specific expression of a splicing mutation in the IKBKAP gene causes familial dysautonomia. Am J Hum Genet (2001) 3.27
Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells. J Clin Invest (1997) 3.22
Comparative analysis of human DNA variations by fluorescence-based sequencing of PCR products. Genomics (1994) 3.06
Sequences in the promoter region of the chicken lysozyme gene required for steroid regulation and receptor binding. Cell (1984) 3.01
Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes. Nucleic Acids Res (1992) 2.89
Negative regulation by glucocorticoids through interference with a cAMP responsive enhancer. Science (1988) 2.78
Contacts between hormone receptor and DNA double helix within a glucocorticoid regulatory element of mouse mammary tumor virus. Proc Natl Acad Sci U S A (1984) 2.64
Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor. EMBO J (1998) 2.58
The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa B DNA binding. Proc Natl Acad Sci U S A (1992) 2.56
Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B. Nature (1992) 2.50
Activation of NF-kappa B in vivo is regulated by multiple phosphorylations. EMBO J (1994) 2.31
Isolation of eukaryotic messenger RNA on cellulose and its translation in vitro. Biochem Biophys Res Commun (1972) 2.21
Glucocorticoid receptors recognize DNA sequences in and around murine mammary tumour virus DNA. EMBO J (1982) 2.21
Molecular definition of the 22q11 deletions in velo-cardio-facial syndrome. Am J Hum Genet (1995) 2.19
Inducible regulatory elements in the human cyclin D1 promoter. Oncogene (1994) 2.16
The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators. Oncogene (1999) 2.15
Transcriptional regulation of the HIV-1 promoter by NF-kappa B in vitro. Genes Dev (1992) 2.12
Increased transcription levels induce higher mutation rates in a hypermutating cell line. J Immunol (2001) 2.11
Hormone induces binding of receptors and transcription factors to a rearranged nucleosome on the MMTV promoter in vivo. EMBO J (1995) 2.09
Acute cytomegalovirus infection complicated by vascular thrombosis: a case report. Clin Infect Dis (2001) 2.08
Steroid hormone receptors: interaction with deoxyribonucleic acid and transcription factors. Endocr Rev (1993) 2.05
NF-kappaB and the innate immune response. Curr Opin Immunol (2000) 2.04
17beta-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells. Oncogene (1996) 2.01
Mutual transrepression of Fos and the glucocorticoid receptor: involvement of a functional domain in Fos which is absent in FosB. EMBO J (1990) 1.97
Different mechanisms control signal-induced degradation and basal turnover of the NF-kappaB inhibitor IkappaB alpha in vivo. EMBO J (1996) 1.97
The Texas Children's Medication Algorithm Project: Report of the Texas Consensus Conference Panel on Medication Treatment of Childhood Attention-Deficit/Hyperactivity Disorder. Part I. Attention-Deficit/Hyperactivity Disorder. J Am Acad Child Adolesc Psychiatry (2000) 1.91
The NF-kappa B precursor p105 and the proto-oncogene product Bcl-3 are I kappa B molecules and control nuclear translocation of NF-kappa B. EMBO J (1993) 1.90
NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes. EMBO J (1999) 1.87
Messenger RNA for hepatic tryptophan oxygenase: its partial purification, its translation in a heterologous cell-free system, and its control by glucocorticoid hormones. Proc Natl Acad Sci U S A (1973) 1.84
High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells. Blood (1996) 1.82
Ubiquitous transcription factor OTF-1 mediates induction of the MMTV promoter through synergistic interaction with hormone receptors. Cell (1991) 1.81
Differential gene activation by glucocorticoids and progestins through the hormone regulatory element of mouse mammary tumor virus. Cell (1988) 1.78
Glucocorticoid receptor binding and activation of a heterologous promoter by dexamethasone by the first intron of the human growth hormone gene. Mol Cell Biol (1985) 1.78
Common structural constituents confer I kappa B activity to NF-kappa B p105 and I kappa B/MAD-3. EMBO J (1993) 1.77
Maintenance of NF-kappa B activity is dependent on protein synthesis and the continuous presence of external stimuli. Mol Cell Biol (1991) 1.74
Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells. Oncogene (1999) 1.71
Steroid-free glucocorticoid receptor binds specifically to mouse mammary tumour virus DNA. Nature (1987) 1.70
Requirement of NF-kappaB/Rel for the development of hair follicles and other epidermal appendices. Development (2001) 1.69
An inhibitor domain in Sp3 regulates its glutamine-rich activation domains. EMBO J (1996) 1.68
Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha. Mol Cell Biol (2001) 1.66
Glucocorticoid-binding proteins of rat liver cytosol. I. Separation and identification of the binding proteins. J Biol Chem (1972) 1.65
The NF-kappa B/Rel and I kappa B gene families: mediators of immune response and inflammation. J Mol Med (Berl) (1996) 1.64
Purified octamer binding transcription factors stimulate RNA polymerase III--mediated transcription of the 7SK RNA gene. Cell (1989) 1.61
Functional interference of Sp1 and NF-kappaB through the same DNA binding site. Mol Cell Biol (1998) 1.60
Periodic cdc25C transcription is mediated by a novel cell cycle-regulated repressor element (CDE). EMBO J (1995) 1.54
Attention deficit/hyperactivity disorder children with a 7-repeat allele of the dopamine receptor D4 gene have extreme behavior but normal performance on critical neuropsychological tests of attention. Proc Natl Acad Sci U S A (2000) 1.53
Overexpression of I kappa B alpha without inhibition of NF-kappaB activity and mutations in the I kappa B alpha gene in Reed-Sternberg cells. Blood (1999) 1.53
The uteroglobin gene region: hormonal regulation, repetitive elements and complete nucleotide sequence of the gene. Nucleic Acids Res (1983) 1.52
The nucleotide sequences recognized by the glucocorticoid receptor in the rabbit uteroglobin gene region are located far upstream from the initiation of transcription. EMBO J (1984) 1.51
The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component. J Biol Chem (2000) 1.49
Classification of pressure ulcers. Arch Dermatol (1990) 1.48
Registered Replication Report: Schooler and Engstler-Schooler (1990). Perspect Psychol Sci (2014) 1.48
Two-step synergism between the progesterone receptor and the DNA-binding domain of nuclear factor 1 on MMTV minichromosomes. Mol Cell (1999) 1.44
Velo-cardio-facial syndrome: frequency and extent of 22q11 deletions. Am J Med Genet (1995) 1.43
Separate and combined effects of methylphenidate and behavior modification on boys with attention deficit-hyperactivity disorder in the classroom. J Consult Clin Psychol (1993) 1.40
Cell-free translation of the globin message within polydisperse high-molecular-weight ribonucleic acid of avian erythrocytes. Proc Natl Acad Sci U S A (1973) 1.38
All human genes of the uteroglobin family are localized on chromosome 11q12.2 and form a dense cluster. Ann N Y Acad Sci (2000) 1.38
High expression of RelA/p65 is associated with activation of nuclear factor-kappaB-dependent signaling in pancreatic cancer and marks a patient population with poor prognosis. Br J Cancer (2007) 1.37
Chlamydia pneumoniae infection of vascular smooth muscle and endothelial cells activates NF-kappaB and induces tissue factor and PAI-1 expression: a potential link to accelerated arteriosclerosis. Circulation (1999) 1.37
Receptors for glucocorticosteroid and progesterone recognize distinct features of a DNA regulatory element. Proc Natl Acad Sci U S A (1986) 1.34
Functional analyses of the transcription factor Sp4 reveal properties distinct from Sp1 and Sp3. J Biol Chem (1995) 1.34
NF-kappa B precursor p100 inhibits nuclear translocation and DNA binding of NF-kappa B/rel-factors. Oncogene (1993) 1.32
Contacts between steroid hormone receptors and thymines in DNA: an interference method. Proc Natl Acad Sci U S A (1990) 1.30
Nuclear factor I acts as a transcription factor on the MMTV promoter but competes with steroid hormone receptors for DNA binding. EMBO J (1990) 1.29
Moderate increase in histone acetylation activates the mouse mammary tumor virus promoter and remodels its nucleosome structure. Proc Natl Acad Sci U S A (1996) 1.28
Patient referral by telemedicine: effectiveness and cost analysis of an Intranet system. J Telemed Telecare (2000) 1.28
Tissue-specific expression, hormonal regulation and 5'-flanking gene region of the rat Clara cell 10 kDa protein: comparison to rabbit uteroglobin. Nucleic Acids Res (1990) 1.27
Peak height variations in automated sequencing of PCR products using Taq dye-terminator chemistry. Biotechniques (1995) 1.26
The effect of cortisol on the binding of actinomycin D to and on the template activity of isolated rat liver chromatin. Arch Biochem Biophys (1970) 1.25
Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells. Leukemia (2000) 1.23
A model for hormone receptor binding to the mouse mammary tumour virus regulatory element based on hydroxyl radical footprinting. Nucleic Acids Res (1988) 1.23
Inducible regulatory elements in the human cyclin D1 promoter. Oncogene (1994) 1.23
Transformation-dependent susceptibility of rat hepatic stellate cells to apoptosis induced by soluble Fas ligand. Hepatology (1998) 1.19
Immunolocalization of gluco- and mineralocorticoid receptors in rabbit kidney. Am J Physiol (1991) 1.19
Partial overlapping of binding sequences for steroid hormone receptors and DNaseI hypersensitive sites in the rabbit uteroglobin gene region. Nucleic Acids Res (1987) 1.19
Members of the Sp transcription factor family control transcription from the uteroglobin promoter. J Biol Chem (1995) 1.18
Brainstem auditory evoked potentials in postconcussion dizziness. Arch Neurol (1980) 1.18