Published in Prog Clin Biol Res on January 01, 1987
Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. Hum Mol Genet (2005) 4.12
Hepatocytes from non-hepatic adult stem cells. Nature (2000) 3.27
Epidermal growth factor (EGF/URO) induces expression of regulatory peptides in damaged human gastrointestinal tissues. J Pathol (1990) 2.29
Identification of a metaplastic cell lineage associated with human gastric adenocarcinoma. Lab Invest (1999) 2.10
A novel gene (PLU-1) containing highly conserved putative DNA/chromatin binding motifs is specifically up-regulated in breast cancer. J Biol Chem (1999) 2.09
Trefoil peptide gene expression in gastrointestinal epithelial cells in inflammatory bowel disease. Gastroenterology (1993) 1.97
E-cadherin expression in colorectal cancer. An immunocytochemical and in situ hybridization study. Am J Pathol (1993) 1.89
Bcl-2 expression in adult and embryonic non-haematopoietic tissues. J Pathol (1993) 1.78
CUX1: target of Akt signalling and mediator of resistance to apoptosis in pancreatic cancer. Gut (2010) 1.63
Bone marrow derivation of pericryptal myofibroblasts in the mouse and human small intestine and colon. Gut (2002) 1.60
Coordinated localisation of mucins and trefoil peptides in the ulcer associated cell lineage and the gastrointestinal mucosa. Gut (2000) 1.59
Molecular cloning and tissue expression of FAT, the human homologue of the Drosophila fat gene that is located on chromosome 4q34-q35 and encodes a putative adhesion molecule. Genomics (1995) 1.59
Wnt5a cloning, expression, and up-regulation in human primary breast cancers. Clin Cancer Res (1995) 1.56
Spasmolytic polypeptide is a major antral peptide: distribution of the trefoil peptides human spasmolytic polypeptide and pS2 in the stomach. Gastroenterology (1993) 1.55
hP1.B, a human P-domain peptide homologous with rat intestinal trefoil factor, is expressed also in the ulcer-associated cell lineage and the uterus. Proc Natl Acad Sci U S A (1993) 1.48
The epidermal growth factor receptor in human pancreatic cancer. J Pathol (1992) 1.47
Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types. J Pathol (1998) 1.41
Trefoil peptides. Gut (1999) 1.41
Expression of the Met/hepatocyte growth factor receptor in human pancreatic cancer. Cancer Res (1995) 1.40
Transgenic mice that overexpress the human trefoil peptide pS2 have an increased resistance to intestinal damage. Proc Natl Acad Sci U S A (1996) 1.29
Level of expression of E-cadherin mRNA in colorectal cancer correlates with clinical outcome. Br J Cancer (1995) 1.26
An alpha2,3 sialyltransferase (ST3Gal I) is elevated in primary breast carcinomas. Glycobiology (1999) 1.23
The ulceration-associated cell lineage (UACL) reiterates the Brunner's gland differentiation programme but acquires the proliferative organization of the gastric gland. J Pathol (1994) 1.23
Stromelysin 3: an independent prognostic factor for relapse-free survival in node-positive breast cancer and demonstration of novel breast carcinoma cell expression. Am J Pathol (1998) 1.20
Up-regulation of macrophage wnt gene expression in adenoma-carcinoma progression of human colorectal cancer. Br J Cancer (1999) 1.19
Interactions between stromal cell--derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia. J Clin Invest (1998) 1.19
Paneth cell granule depletion in the human small intestine under infective and nutritional stress. Clin Exp Immunol (2004) 1.18
The expression of the trefoil peptides pS2 and human spasmolytic polypeptide (hSP) in 'gastric metaplasia' of the proximal duodenum: implications for the nature of 'gastric metaplasia'. J Pathol (1993) 1.17
The hypoxia-inducible genes VEGF and CA9 are differentially regulated in superficial vs invasive bladder cancer. Br J Cancer (2002) 1.16
Differential expression of vascular endothelial growth factor mRNA vs protein isoform expression in human breast cancer and relationship to eIF-4E. Br J Cancer (1998) 1.16
Update on hepatic stem cells. Liver (2001) 1.15
Bone marrow transplantation ameliorates pathology in interleukin-10 knockout colitic mice. J Pathol (2006) 1.12
Allelic loss at SMAD4 in polyps from juvenile polyposis patients and use of fluorescence in situ hybridization to demonstrate clonal origin of the epithelium. Cancer Res (2000) 1.11
The new stem cell biology: something for everyone. Mol Pathol (2003) 1.10
MT1-MMP and MMP-2 mRNA expression in human ovarian tumors: possible implications for the role of desmoplastic fibroblasts. Hum Pathol (1998) 1.09
Keratinocyte growth factor in inflammatory bowel disease. Increased mRNA transcripts in ulcerative colitis compared with Crohn's disease in biopsies and isolated mucosal myofibroblasts. Am J Pathol (1997) 1.07
Cell behavior in the acetylaminofluorene-treated regenerating rat liver. Light and electron microscopic observations. Am J Pathol (1994) 1.06
Duodenal-content reflux esophagitis induces the development of glandular metaplasia and adenosquamous carcinoma in rats. Carcinogenesis (2000) 1.06
Expression of beta-catenin in basal cell carcinoma. Br J Dermatol (2003) 1.04
Invasive lobular and invasive ductal carcinoma of the breast show distinct patterns of vascular endothelial growth factor expression and angiogenesis. J Pathol (1998) 1.04
Inhibiting vascular endothelial growth factor receptor-2 signaling reduces tumor burden in the ApcMin/+ mouse model of early intestinal cancer. Carcinogenesis (2006) 1.04
Differential expression of oestrogen receptor and oestrogen inducible genes in gastric mucosa and cancer. Gut (1997) 1.02
Repopulation of human pulmonary epithelium by bone marrow cells: a potential means to promote repair. Tissue Eng (2005) 1.02
Expression of the trefoil peptides pS2 and human spasmolytic polypeptide (hSP) in Barrett's metaplasia and the native oesophageal epithelium: delineation of epithelial phenotype. J Pathol (1994) 1.02
Roles of hepatocyte growth factor and its receptor Met during gastric ulcer healing in rats. Gastroenterology (1997) 1.02
Distribution and expression of pancreatic secretory trypsin inhibitor and its possible role in epithelial restitution. Am J Pathol (1996) 1.02
The production and characterization of a new monoclonal antibody to the trefoil peptide human spasmolytic polypeptide. Histochem J (1994) 1.01
The mucous neck cell in the human gastric corpus: a distinctive, functional cell lineage. J Pathol (1999) 1.01
Isolation and characterization of an epithelial-specific receptor tyrosine kinase from an ovarian cancer cell line. Cell Growth Differ (1994) 1.00
Downregulation of E-cadherin in the reparative epithelium of the human gastrointestinal tract. Am J Pathol (1996) 1.00
The expression of E-cadherin and catenins in sporadic colorectal carcinoma. Hum Pathol (2001) 0.99
Fibroblast growth factor receptor signalling has a role in lobuloalveolar development of the mammary gland. J Cell Sci (1997) 0.98
Identification of transmembrane proteins as potential prognostic markers and therapeutic targets in breast cancer by a screen for signal sequence encoding transcripts. J Pathol (2006) 0.98
The pattern of expression of the microtubule-binding protein RHAMM/IHABP in mammary carcinoma suggests a role in the invasive behaviour of tumour cells. J Pathol (2001) 0.97
Expression and purification of a trefoil peptide motif in a beta-galactosidase fusion protein and its use to search for trefoil-binding sites. Eur J Biochem (1993) 0.96
Localization of intestinal trefoil-factor mRNA in rat stomach and intestine by hybridization in situ. Biochem J (1992) 0.95
Primary mucinous carcinomas of the skin express TFF1, TFF3, estrogen receptor, and progesterone receptors. Am J Surg Pathol (1998) 0.95
Nonuniform expression of a mouse mammary tumor virus-driven int-2/Fgf-3 transgene in pregnancy-responsive breast tumors. Cell Growth Differ (1992) 0.94
Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation. Oncogene (2012) 0.93
Metabolism of MPTP by cytochrome P4502D6 and the demonstration of 2D6 mRNA in human foetal and adult brain by in situ hybridization. Xenobiotica (1997) 0.93
Hyperplastic polyps: a cell lineage which both synthesizes and secretes trefoil-peptides and has phenotypic similarity with the ulcer-associated cell lineage. Am J Pathol (1993) 0.93
Expression of trefoil peptides in the gastric mucosa of transgenic mice overexpressing transforming growth factor-alpha. Growth Factors (1996) 0.92
The gene encoding mouse intestinal trefoil factor: structural organization, partial sequence analysis and mapping to murine chromosome 17q. Gene (1996) 0.92
In situ analysis of LKB1/STK11 mRNA expression in human normal tissues and tumours. J Pathol (2000) 0.92
The cellular origin and proliferative status of regenerating renal parenchyma after mercuric chloride damage and erythropoietin treatment. Cell Prolif (2007) 0.92
Comprehensive analysis of SMAD4 mutations and protein expression in juvenile polyposis: evidence for a distinct genetic pathway and polyp morphology in SMAD4 mutation carriers. Am J Pathol (2001) 0.92
mRNA expression profiling of phyllodes tumours of the breast: identification of genes important in the development of borderline and malignant phyllodes tumours. J Pathol (2008) 0.92
Basal cell carcinoma development is associated with induction of the expression of the transcription factor Gli-1. Br J Dermatol (1998) 0.92
BAG-i expression in human breast cancer: interrelationship between BAG-1 RNA, protein, HSC70 expression and clinico-pathological data. J Pathol (2002) 0.91
Top down or bottom up? Competing management structures in the morphogenesis of colorectal neoplasms. Gut (2002) 0.91
Trefoil factor expression in normal and diseased human salivary glands. Hum Pathol (2000) 0.90
Lack of inducible nitric oxide synthase promotes intestinal tumorigenesis in the Apc(Min/+) mouse. Gastroenterology (2001) 0.90
The development of duodenal microadenomas in FAP patients: the human correlate of the Min mouse. J Pathol (2008) 0.90
Analysis of foetal expression sites of human type II DNA topoisomerase alpha and beta mRNAs by in situ hybridisation. Biochim Biophys Acta (1996) 0.90
Trefoil peptide gene expression in gastrointestinal epithelial cells in inflammatory bowel disease. Scand J Gastroenterol Suppl (1992) 0.89
Tumour-promoting activity of altered WWP1 expression in breast cancer and its utility as a prognostic indicator. J Pathol (2008) 0.88
Regulation of stromal cell cyclooxygenase-2 in the ApcMin/+ mouse model of intestinal tumorigenesis. Carcinogenesis (2005) 0.88
Effect of ectopic expression of rat trefoil factor family 3 (intestinal trefoil factor) in the jejunum of transgenic mice. J Biol Chem (2001) 0.87
Haematopoietic lineage-committed bone marrow cells, but not cloned cultured mesenchymal stem cells, contribute to regeneration of renal tubular epithelium after HgCl 2 -induced acute tubular injury. Cell Prolif (2008) 0.87
Ulcer associated cell lineage glands expressing trefoil peptide genes are induced by chronic ulceration in ileal pouch mucosa. Gut (2001) 0.87
Expression of oestrogen receptor and oestrogen-inducible genes in pancreatic cancer. Br J Surg (1997) 0.87
H-RYK, an unusual receptor kinase: isolation and analysis of expression in ovarian cancer. Mol Med (1996) 0.86
Expression of hepatocyte growth factor mRNA during oval cell activation in the rat liver. J Pathol (1993) 0.86
Hepatic and renal differentiation from blood-borne stem cells. Gene Ther (2002) 0.86
The cloning, mapping and expression of a novel gene, BRL, related to the AF10 leukaemia gene. Oncogene (1999) 0.85
Expression of two related viral early genes in Epstein-Barr virus-associated tumors. J Virol (2000) 0.84
Keratinocyte growth factor and coeliac disease. Gut (2001) 0.83
Trefoil peptides: mitogens, motogens, or mirages? J Clin Gastroenterol (1997) 0.83
Expression of oestrogen receptor and oestrogen-inducible genes pS2 and ERD5 in large bowel mucosa and cancer. J Pathol (1998) 0.82
Morphological changes of organs after sucrose or fructose feeding. Prog Biochem Pharmacol (1986) 0.82
Proliferative populations in intestinal metaplasia: evidence of deregulation in Paneth and goblet cells, but not endocrine cells. J Pathol (2000) 0.82
Inhibition of hexonate dehydrogenase and aldose reductase from bovine retina by sorbinil, statil, M79175 and valproate. Biochem Pharmacol (1986) 0.82
Expression of trefoil peptides pS2 and human spasmolytic polypeptide in gastric metaplasia at the margin of duodenal ulcers. Gut (1995) 0.81
Vascular endothelial growth factor transgenic mice exhibit reduced male fertility and placental rejection. Mol Hum Reprod (2001) 0.81
Lysozyme gene expression in inflammatory bowel disease. Gastroenterology (1992) 0.81
Advantages of in situ hybridisation over direct or indirect in situ reverse transcriptase-polymerase chain reaction for localisation of galanin mRNA expression in rat small intestine and pituitary. Histochem J (2001) 0.80
Identification by differential display of a protein phosphatase-2A regulatory subunit preferentially expressed in malignant melanoma cells. Int J Cancer (1999) 0.80
Recipes for adult stem cell plasticity: fusion cuisine or readymade? J Clin Pathol (2004) 0.79
The effects of an aldose reductase inhibitor upon the sorbitol pathway, fructose-1-phosphate and lactate in the retina and nerve of streptozotocin-diabetic rats. Exp Eye Res (1983) 0.79