Published in Eur J Clin Invest on June 01, 1987
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Time course of acetaminophen-protein adducts and acetaminophen metabolites in circulation of overdose patients and in HepaRG cells. Xenobiotica (2015) 0.83
PharmGKB summary: pathways of acetaminophen metabolism at the therapeutic versus toxic doses. Pharmacogenet Genomics (2015) 0.78
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Polymorphic dextromethorphan metabolism: co-segregation of oxidative O-demethylation with debrisoquin hydroxylation. Clin Pharmacol Ther (1985) 2.50
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The teaching and organisation of clinical pharmacology in European medical schools (W.H.O. Working Group on Clinical Pharmacology). Eur J Clin Pharmacol (1990) 2.07
Asthma experience in an occupational and environmental medicine clinic. Low-dose reactive airways dysfunction syndrome. J Occup Med (1994) 1.74
Plasma concentrations of mebendazole during treatment of echinococcosis: preliminary results. Eur J Clin Pharmacol (1980) 1.73
Superiority of the Child-Pugh classification to quantitative liver function tests for assessing prognosis of liver cirrhosis. Scand J Gastroenterol (1989) 1.72
Point mutations in the L-type pyruvate kinase gene of two children with hemolytic anemia caused by pyruvate kinase deficiency. Blood (1991) 1.63
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Steady-state extrarenal sorbitol clearance as a measure of hepatic plasma flow. Gastroenterology (1988) 1.53
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Increased systemic availability of albendazole when taken with a fatty meal. Eur J Clin Pharmacol (1988) 1.48
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UDP-glucuronyltransferase in perfused rat liver and in microsomes - III. Effects of galactosamine and carbon tetrachloride on the glucuronidation of 1-naphthol and bilirubin. Biochem Pharmacol (1976) 1.47
Quantitative liver function tests as surrogate markers for end-points in controlled clinical trials: a retrospective feasibility study. Hepatology (1997) 1.43
Expiratory measurement of maximal amino-pyrine demethylation in vivo: effect of phenobarbital, partial hepatectomy, protacaval shunt and bile duct ligation in the rat. J Pharmacol Exp Ther (1976) 1.41
The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence. DNA Cell Biol (1991) 1.35
Aminopyrine demethylation measured by breath analysis in cirrhosis. Clin Pharmacol Ther (1976) 1.35
Ankyrin-1 mutations are a major cause of dominant and recessive hereditary spherocytosis. Nat Genet (1996) 1.32
Lactulose in the treatment of portal-systemic encephalopathy. Report of a symposium. Gastroenterology (1970) 1.26
The influence of carbohydrate gelling agents on rat intestinal transport of monosaccharides and neutral amino acids in vitro. Clin Sci (Lond) (1980) 1.25
[Prevalence of Gilbert's syndrome in Germany]. Dtsch Med Wochenschr (1987) 1.23
Localization and turnover studies of membrane nicotinamide adenine dinucleotide glycohydrolase in rat liver. J Biol Chem (1971) 1.19
Direct determination of Helicobacter pylori vacA genotypes and cagA gene in gastric biopsies and relationship to gastrointestinal diseases. Am J Gastroenterol (1999) 1.16
Variable clinical severity of hereditary spherocytosis: relation to erythrocytic spectrin concentration, osmotic fragility, and autohemolysis. J Pediatr (1990) 1.14
UDP-glucuronosyltransferase activities. Guidelines for consistent interim terminology and assay conditions. Biochem Pharmacol (1983) 1.14
Serum concentrations of amiodarone during long term therapy. Relation to dose, efficacy and toxicity. Eur J Clin Pharmacol (1983) 1.13
Quantitative analysis of enzyme-altered liver foci in rats initiated with diethylnitrosamine and promoted with 2,3,7,8-tetrachlorodibenzo-p-dioxin or 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol (1996) 1.12
Turnover of heme and protein moieties of rat liver microsomal cytochrome b5. Biochem Biophys Res Commun (1970) 1.11
Prevalence of increased osmotic fragility of erythrocytes in German blood donors: screening using a modified glycerol lysis test. Ann Hematol (1992) 1.11
Measuring the effects of topical moisturizers on changes in stratum corneum thickness, water gradients and hydration in vivo. Br J Dermatol (2008) 1.11
Rate of drug metabolism in man measured by 14CO2-breath analysis. Eur J Clin Pharmacol (1978) 1.08
Application of RHD and RHCE genotyping for correct blood group determination in chronically transfused patients. Transfusion (1999) 1.06
Separation and partial purification of two differentially inducible UDP-glucuronyltransferases from rat liver. Biochem Pharmacol (1977) 1.06
Regulation of -aminolevulinic acid synthetase by drugs and steroids in vivo and in isolated perfused rat liver. Eur J Biochem (1971) 1.05
The selenium state of children. II. Selenium content of serum, whole blood, hair and the activity of erythrocyte glutathione peroxidase in dietetically treated patients with phenylketonuria and maple-syrup-urine disease. Eur J Pediatr (1978) 1.04
Molecular basis of neurological dysfunction coupled with haemolytic anaemia in human glucose-6-phosphate isomerase (GPI) deficiency. Hum Genet (1998) 1.04
Ursodeoxycholic acid-induced changes of plasma and urinary bile acids in patients with primary biliary cirrhosis. Hepatology (1990) 1.02
UDP-glucuronyltransferase in perfused rat liver and in microsomes: influence of phenobarbital and 3-methylcholanthrene. Eur J Biochem (1974) 1.02
Purification of rat-liver microsomal UDP-glucuronyltransferase. Separation of two enzyme forms inducible by 3-methylcholanthrene or phenobarbital. Eur J Biochem (1979) 1.01
Effect of plasma mebendazole concentrations in the treatment of human echinococcosis. Am J Trop Med Hyg (1985) 1.01
Motion adaptation governs the shape of motion-evoked cortical potentials. Vision Res (1994) 1.01
[Bacterial endocarditis due to an actinobacillus]. Dtsch Med Wochenschr (1967) 1.01
[Early diagnosis of neonatal infection]. Monatsschr Kinderheilkd (1985) 1.00
Genomic alterations of the c-myc protooncogene in relation to the overexpression of c-erbB2 and Ki-67 in human breast and cervix carcinomas. J Cancer Res Clin Oncol (1991) 0.99
New developments in glucuronidation research: report of a workshop on "glucuronidation, its role in health and disease". Hepatology (1992) 0.99
Short stature and failure of pubertal development in thalassaemia major: evidence for hypothalamic neurosecretory dysfunction of growth hormone secretion and defective pituitary gonadotropin secretion. Eur J Pediatr (1997) 0.97
Frequency of very late fatal sepsis after splenectomy for hereditary spherocytosis: impact of insufficient antibody response to pneumococcal infection. Ann Hematol (1999) 0.97
Differential induction of rat liver microsomal UDP-glucuronosyltransferase activites by various inducing agents. Biochem Pharmacol (1982) 0.97
Determination of microsomal UDP-glucuronyltransferase in needle-biopsy specimens of human liver. Eur J Clin Pharmacol (1978) 0.97
Treatment of hydatid disease with high oral doses of mebendazole. Long-term follow-up of plasma mebendazole levels and drug interactions. Eur J Clin Pharmacol (1986) 0.96
Treatment of chronic portal-systemic encephalopathy with lactulose. Report of six patients and review of the literature. Am J Med (1971) 0.96
Inhibition by antidepressant drugs of cyclic AMP response element-binding protein/cyclic AMP response element-directed gene transcription. Mol Pharmacol (1995) 0.96
Involvement of the Ca(2+)-dependent phosphatase calcineurin in gene transcription that is stimulated by cAMP through cAMP response elements. J Biol Chem (1995) 0.96
A distribution study of CYP1A2 phenotypes among smokers and non-smokers in a cohort of healthy Caucasian volunteers. Eur J Clin Pharmacol (1998) 0.95
Paracetamol as a test drug to determine glucuronide formation in man. Effects of inducers and of smoking. Eur J Clin Pharmacol (1987) 0.95
Chemotherapy of alveolar echinococcosis. Comparison of plasma mebendazole concentrations in animals and man. Eur J Clin Pharmacol (1981) 0.95
Contrast dependency of motion-onset and pattern-reversal VEPs: interaction of stimulus type, recording site and response component. Vision Res (1997) 0.94
Inhibition of cAMP-responsive element-mediated gene transcription by cyclosporin A and FK506 after membrane depolarization. J Biol Chem (1993) 0.94
Primary reactions of sensory rhodopsins. Proc Natl Acad Sci U S A (2001) 0.94
Assessment of the cytochrome P-448 dependent liver enzyme system by a caffeine breath test. Eur J Clin Pharmacol (1981) 0.94
Inhibition of MafA transcriptional activity and human insulin gene transcription by interleukin-1beta and mitogen-activated protein kinase kinase kinase in pancreatic islet beta cells. Diabetologia (2007) 0.94
Inhibition of CREB- and cAMP response element-mediated gene transcription by the immunosuppressive drugs cyclosporin A and FK506 in T cells. Naunyn Schmiedebergs Arch Pharmacol (1997) 0.93
Induction of human UDP glucuronosyltransferases (UGT1A6, UGT1A9, and UGT2B7) by t-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin in Caco-2 cells. Drug Metab Dispos (1999) 0.93
Gene-specific transcriptional activity of the insulin cAMP-responsive element is conferred by NF-Y in combination with cAMP response element-binding protein. J Biol Chem (1998) 0.93
Absorption of inorganic and food iron in children with heterozygous and homozygous beta-thalassemia. Z Kinderheilkd (1973) 0.93
Urinary caffeine metabolites in man. Age-dependent changes and pattern in various clinical situations. Eur J Clin Pharmacol (1992) 0.93
The 30-minute aminopyrine breath test: optimization of sampling times after intravenous administration of 14C-aminopyrine. Digestion (1988) 0.93
Hepatic functional deterioration after portacaval shunt in the rat. Effects on sulfobromophthalein transport-maximum, indocyanine green clearance and galactose elimination capacity. Gastroenterology (1976) 0.93
[Positive diagnosis of Gilbert syndrome. Retrospective analysis of 59 cases with special reference to the nicotinic acid test]. Schweiz Med Wochenschr (1982) 0.92
Triosephosphate isomerase deficiency: haemolytic anaemia, myopathy with altered mitochondria and mental retardation due to a new variant with accelerated enzyme catabolism and diminished specific activity. Eur J Pediatr (1991) 0.92
Penetration of ciprofloxacin into the cerebrospinal fluid of patients with uninflamed meninges. J Antimicrob Chemother (1990) 0.92
Dioxinlike components in incinerator fly ash: a comparison between chemical analysis data and results from a cell culture bioassay. Environ Health Perspect (1997) 0.92
Metabolism of naphthalene to naphthalene dihydrodiol glucuronide in isolated hepatocytes and in liver microsomes. Biochem Pharmacol (1976) 0.92
Dose dependence of the 14C-aminopyrine breath test. Intrasubject comparison of tracer and pharmacological doses. Eur J Clin Pharmacol (1977) 0.92
High oral doses of mebendazole interfere with growth of larval Echinococcus multilocularis lesions. J Hepatol (1985) 0.92
Membrane depolarization and calcium influx induce glucagon gene transcription in pancreatic islet cells through the cyclic AMP-responsive element. J Biol Chem (1993) 0.91
Regulation of delta-aminolevulinic acid synthetase by drugs and steroids in isolated perfused rat liver. Enzyme (1973) 0.90
Assessment of biological activities of mixtures of polychlorinated dibenzo-p-dioxins: comparison between defined mixtures and their constituents. Arch Toxicol (1991) 0.90
Quantitative assessment of deranged hepatic function: a missed opportunity? Semin Liver Dis (1983) 0.89
The German Environmental Survey 1990/92 (GerES II): sources of personal exposure to volatile organic compounds. J Expo Anal Environ Epidemiol (2000) 0.89
Amiodarone-induced vasculitis and polyserositis. Postgrad Med J (1985) 0.89
Characterization of a novel calcium response element in the glucagon gene. J Biol Chem (1999) 0.88
Characterization of a novel protein kinase C response element in the glucagon gene. Mol Cell Biol (1997) 0.88
The role of conjugation reactions in detoxication. Arch Toxicol (1987) 0.88
Assessment of biological activities of mixtures of polychlorinated dibenzo-p-dioxins (PCDDs) and their constituents in human HepG2 cells. Arch Toxicol (1992) 0.88
Comparison of serine and hippurate as precursor equivalents during infusion of [15N]glycine for measurement of fractional synthetic rates of apolipoprotein B of very-low-density lipoprotein. Metabolism (1995) 0.87
A new look at the plasma disappearance of sulfobromophthalein (BSP): correlation with the BSP transport maximum and the hepatic plasma flow in man. J Lab Clin Med (1976) 0.87
Combined glucosephosphate isomerase and glucose-6-phosphate dehydrogenase deficiency of the erythrocytes: a new haemolytic syndrome. Br J Haematol (1971) 0.87
Assessment of the hepatic circulation in humans: new concepts based on evidence derived from a D-sorbitol clearance method. J Lab Clin Med (1998) 0.87
Organization of enzymes of glycolysis and of glutathione metabolism in human red cell membranes. Biochim Biophys Acta (1975) 0.87
Inhibition of membrane depolarisation-induced transcriptional activity of cyclic AMP response element binding protein (CREB) by the dual-leucine-zipper-bearing kinase in a pancreatic islet beta cell line. Diabetologia (2005) 0.86
Functional heterogeneity of UDP-glucuronyltransferase in rat tissues. Biochem Pharmacol (1980) 0.86
Hyperphagia in children with craniopharyngioma is associated with hyperleptinaemia and a failure in the downregulation of appetite. Eur J Endocrinol (1998) 0.86
UDP-glucuronyltransferase in perfused rat liver and in microsomes. Effects of CCl4 injury. Naunyn Schmiedebergs Arch Pharmacol (1977) 0.86
Inhibition of apoptosis during 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated tumour promotion in rat liver. Carcinogenesis (1995) 0.86