Comparison between 1-deoxynojirimycin and N-methyl-1-deoxynojirimycin as inhibitors of oligosaccharide processing in intestinal epithelial cells.

PubWeight™: 0.99‹?› | Rank: Top 15%

🔗 View Article (PMC 1144771)

Published in Biochem J on March 15, 1985

Authors

P A Romero, B Saunier, A Herscovics

Articles citing this

Aminosugar derivatives as potential anti-human immunodeficiency virus agents. Proc Natl Acad Sci U S A (1988) 1.75

Yeast KRE2 defines a new gene family encoding probable secretory proteins, and is required for the correct N-glycosylation of proteins. Genetics (1992) 1.46

Transformation by the v-fms oncogene product: role of glycosylational processing and cell surface expression. Mol Cell Biol (1985) 1.22

Different effects of the glucosidase inhibitors 1-deoxynojirimycin, N-methyl-1-deoxynojirimycin and castanospermine on the glycosylation of rat alpha 1-proteinase inhibitor and alpha 1-acid glycoprotein. Biochem J (1986) 0.96

Ktr1p is an alpha-1,2-mannosyltransferase of Saccharomyces cerevisiae. Comparison of the enzymic properties of soluble recombinant Ktr1p and Kre2p/Mnt1p produced in Pichia pastoris. Biochem J (1997) 0.91

Inhibition of alpha-glucosidase I of the glycoprotein-processing enzymes by 6-O-butanoyl castanospermine (MDL 28,574) and its consequences in human immunodeficiency virus-infected T cells. Antimicrob Agents Chemother (1994) 0.86

Disruption of the processing alpha-mannosidase gene does not prevent outer chain synthesis in Saccharomyces cerevisiae. Biochem J (1993) 0.85

Inhibition of myoblast fusion by the glucosidase inhibitor N-methyl-1-deoxynojirimycin, but not by the mannosidase inhibitor 1-deoxymannojirimycin. Biochem J (1986) 0.82

Adaptive responses to pharmacological inhibition of small intestinal alpha-glucosidases in the rat. Gut (1987) 0.75

Articles cited by this

Detection of sugars on paper chromatograms. Nature (1950) 52.74

Synthesis and processing of asparagine-linked oligosaccharides. Annu Rev Biochem (1981) 11.44

Inhibition of N-linked complex oligosaccharide formation by 1-deoxynojirimycin, an inhibitor of processing glucosidases. J Biol Chem (1982) 1.93

Castanospermine inhibits the processing of the oligosaccharide portion of the influenza viral hemagglutinin. Biochemistry (1983) 1.75

Purification by affinity chromatography of glucosidase I, an endoplasmic reticulum hydrolase involved in the processing of asparagine-linked oligosaccharides. Eur J Biochem (1984) 1.65

Glycoprotein biosynthesis. Rat liver microsomal glucosidases which process oligosaccharides. J Biol Chem (1979) 1.38

N-methyl-1-deoxynojirimycin, a novel inhibitor of glycoprotein processing, and its effect on fowl plague virus maturation. Virology (1983) 1.32

Characterization of a glucosidase involved in an initial step in the processing of oligosaccharide chains. J Biol Chem (1980) 1.31

1-deoxynojirimycin impairs oligosaccharide processing of alpha 1-proteinase inhibitor and inhibits its secretion in primary cultures of rat hepatocytes. J Biol Chem (1983) 1.27

Microsomal glucosidases of rat liver. Partial purification and inhibition by disaccharides. Eur J Biochem (1980) 1.19

A lectin-resistant mouse lymphoma cell line is deficient in glucosidase II, a glycoprotein-processing enzyme. J Biol Chem (1982) 1.12

Partial purification and characterization of the glucosidases involved in the processing of asparagine-linked oligosaccharides. Arch Biochem Biophys (1980) 1.07

Inhibition of formation of complex oligosaccharides by the glucosidase inhibitor bromoconduritol. Proc Natl Acad Sci U S A (1982) 1.06

Cell-density-dependent changes in cell-surface glycopeptides and in adhesion of cultured intestinal epithelial cells. Biochem J (1982) 1.01

Partial purification from Saccharomyces cerevisiae of a soluble glucosidase which removes the terminal glucose from the oligosaccharide Glc3Man9GlcNAc2. J Biol Chem (1981) 0.97

The biosynthetic pathway of the asparagine-linked oligosaccharides of glycoproteins. CRC Crit Rev Biochem (1982) 0.96

Molecular events involved in 1,25-dihydroxyvitamin D3 stimulation of intestinal calcium transport. Fed Proc (1982) 0.86

Articles by these authors

Radioautographic visualization of the incorporation of galactose-3H and mannose-3H by rat thyroids in vitro in relation to the stages of thyroglobulin synthesis. J Cell Biol (1969) 3.12

A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation. EMBO Rep (2001) 2.96

Overexpression and overactivation of Akt in thyroid carcinoma. Cancer Res (2001) 2.51

Inhibition of N-linked complex oligosaccharide formation by 1-deoxynojirimycin, an inhibitor of processing glucosidases. J Biol Chem (1982) 1.93

Synthesis of cellulose precursors. The involvement of lipid-linked sugars. Eur J Biochem (1978) 1.58

Biosynthesis of thyroglobulin. Incorporation of [1-14C] galactose, [1-14C] manose and [4,5-3H2] leucine into soluble proteins by rat thyroids in vitro. Biochem J (1969) 1.52

Glycosidases of the asparagine-linked oligosaccharide processing pathway. Glycobiology (1994) 1.48

Radioautographic study of in vivo and in vitro incorporation of fucose-3H into thyroglobulin by rat thyroid follicular cells. J Cell Biol (1971) 1.44

Cloning and expression of a specific human alpha 1,2-mannosidase that trims Man9GlcNAc2 to Man8GlcNAc2 isomer B during N-glycan biosynthesis. Glycobiology (1999) 1.39

Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases. J Biol Chem (2000) 1.36

N-methyl-1-deoxynojirimycin, a novel inhibitor of glycoprotein processing, and its effect on fowl plague virus maturation. Virology (1983) 1.32

Glycoprotein biosynthesis in Saccharomyces cerevisiae. Isolation and characterization of the gene encoding a specific processing alpha-mannosidase. J Biol Chem (1991) 1.29

Transformation by the v-fms oncogene product: role of glycosylational processing and cell surface expression. Mol Cell Biol (1985) 1.22

The expression of thyrotropin receptor in the brain. Endocrinology (2001) 1.14

Crystal structure of a class I alpha1,2-mannosidase involved in N-glycan processing and endoplasmic reticulum quality control. EMBO J (2000) 1.09

Role of the cysteine residues in the alpha1,2-mannosidase involved in N-glycan biosynthesis in Saccharomyces cerevisiae. The conserved Cys340 and Cys385 residues form an essential disulfide bond. J Biol Chem (1996) 1.09

Characterization of a specific alpha-mannosidase involved in oligosaccharide processing in Saccharomyces cerevisiae. J Biol Chem (1985) 1.07

Mediation by arachidonic acid metabolites of the H2O2-induced stimulation of mitogen-activated protein kinases (extracellular-signal-regulated kinase and c-Jun NH2-terminal kinase). Eur J Biochem (1997) 1.07

Inhibition of formation of complex oligosaccharides by the glucosidase inhibitor bromoconduritol. Proc Natl Acad Sci U S A (1982) 1.06

Cell surface protein disulfide-isomerase is involved in the shedding of human thyrotropin receptor ectodomain. Biochemistry (1996) 1.06

Mannosyltransferase activity in calf pancreas microsomes. Formation from guanosine diphosphate-D-(14C)mannose of a 14C-labeled mannolipid with properties of dolichyl mannopyranosyl phosphate. J Biol Chem (1974) 1.05

Glucosyltransferase activity in calf pancreas microsomes. Formation of dolichyl D[14C]glucosyl phosphate and 14C-labeled lipid-linked oligosaccharides from UDP-D-[14C]glucose. J Biol Chem (1977) 1.05

N-Glycan processing by a lepidopteran insect alpha1,2-mannosidase. Glycobiology (2000) 1.03

Characterization of a cDNA encoding a novel human Golgi alpha 1, 2-mannosidase (IC) involved in N-glycan biosynthesis. J Biol Chem (2000) 1.03

Cell-density-dependent changes in cell-surface glycopeptides and in adhesion of cultured intestinal epithelial cells. Biochem J (1982) 1.01

Substrate specificities of recombinant murine Golgi alpha1, 2-mannosidases IA and IB and comparison with endoplasmic reticulum and Golgi processing alpha1,2-mannosidases. Glycobiology (1998) 1.01

Calcium binding to the class I alpha-1,2-mannosidase from Saccharomyces cerevisiae occurs outside the EF hand motif. Biochemistry (1999) 1.01

On the role of oligosaccharide trimming in the maturation of Sindbis and influenza virus. Arch Virol (1984) 1.01

Inhibitors of protein glycosylation and glycoprotein processing in viral systems. Pharmacol Ther (1987) 1.00

Glycoprotein biosynthesis in Saccharomyces cerevisiae. Characterization of alpha-1,6-mannosyltransferase which initiates outer chain formation. J Biol Chem (1989) 1.00

The yeast CWH41 gene encodes glucosidase I. Glycobiology (1997) 0.97

Partial purification from Saccharomyces cerevisiae of a soluble glucosidase which removes the terminal glucose from the oligosaccharide Glc3Man9GlcNAc2. J Biol Chem (1981) 0.97

The Saccharomyces cerevisiae processing alpha 1,2-mannosidase is localized in the endoplasmic reticulum, independently of known retrieval motifs. Eur J Cell Biol (1996) 0.97

Characterization of glycopeptides labelled from D-[2-3H]mannose and L-[6-3H]fucose in intestinal epithelial cell membranes during differentiation. Biochem J (1980) 0.96

Glucose trimming and mannose trimming affect different phases of the maturation of Sindbis virus in infected BHK cells. Virology (1987) 0.95

Mnt2p and Mnt3p of Saccharomyces cerevisiae are members of the Mnn1p family of alpha-1,3-mannosyltransferases responsible for adding the terminal mannose residues of O-linked oligosaccharides. Glycobiology (1999) 0.94

Mannosyltransferase activity in calf pancreas microsomes. Formation of 14C-labeled lipid-linked oligosaccharides from GDP-D-[14C]mannose and pancreatic dolichyl beta-D-[14C]mannopyranosyl phosphate. J Biol Chem (1977) 0.94

Biosynthesis of thyroglobulin: incorporation of [3H] fucose into proteins by rat thyroids in vitro. Biochem J (1970) 0.94

Transfer of nonglucosylated oligosaccharide from lipid to protein in a mammalian cell. J Biol Chem (1986) 0.93

Glycosyltransferase changes upon differentiation of CaCo-2 human colonic adenocarcinoma cells. Cancer Res (1991) 0.93

Deoxynojirimycin inhibits the formation of Glc3Man9GlcNAc2-PP-dolichol in intestinal epithelial cells in culture. FEBS Lett (1985) 0.92

Morphometry of the lower lumbar vertebrae in patients with and without low back pain. Eur Spine J (2001) 0.92

Effects of inhibitors of N-linked oligosaccharide processing on the biosynthesis and function of insulin and insulin-like growth factor-I receptors. J Biol Chem (1988) 0.91

Ktr1p is an alpha-1,2-mannosyltransferase of Saccharomyces cerevisiae. Comparison of the enzymic properties of soluble recombinant Ktr1p and Kre2p/Mnt1p produced in Pichia pastoris. Biochem J (1997) 0.91

Isolation and characterization of an alpha 1,2-mannosidase cDNA from the lepidopteran insect cell line Sf9. Glycobiology (1997) 0.91

Decrease in polylactosaminoglycans associated with lysosomal membrane glycoproteins during differentiation of CaCo-2 human colonic adenocarcinoma cells. Cancer Res (1989) 0.90

Specificity of the mannosyltransferase which initiates outer chain formation in Saccharomyces cerevisiae. Glycobiology (1991) 0.90

Glycoprotein biosynthesis in Saccharomyces cerevisiae. Purification of the alpha-mannosidase which removes one specific mannose residue from Man9GlcNAc. J Biol Chem (1988) 0.90

On the inhibition of cellulose biosynthesis by coumarin. FEBS Lett (1978) 0.89

Effect of bromolevamisole and other imidazo [2,1-b] thiazole derivatives on adenylate cyclase activity. Biochem Pharmacol (1992) 0.88

The processing alpha1,2-mannosidase of Saccharomyces cerevisiae depends on Rer1p for its localization in the endoplasmic reticulum. Eur J Cell Biol (1999) 0.87

Effect of bacitracin on the biosynthesis of dolichol derivatives in calf pancreas microsomes. FEBS Lett (1977) 0.87

Biosynthesis of dolichol phosphate by subcellular fractions from liver. FEBS Lett (1977) 0.86

Surface-membrane biogenesis in rat intestinal epithelial cells at different stages of maturation. Biochem J (1980) 0.85

Processing of the precursors of the human thyroid-stimulating hormone receptor in various eukaryotic cells (human thyrocytes, transfected L cells and baculovirus-infected insect cells). Eur J Biochem (1994) 0.85

Disruption of the processing alpha-mannosidase gene does not prevent outer chain synthesis in Saccharomyces cerevisiae. Biochem J (1993) 0.85

Anomeric configuration of the dolichyl D-mannosyl phosphate formed in calf pancreas microsomes. J Biol Chem (1975) 0.85

Cell surface glycopeptides from human intestinal epithelial cell lines derived from normal colon and colon adenocarcinomas. Cancer Res (1985) 0.85

Glycoprotein biosynthesis in Saccharomyces cerevisiae. Partial purification of the alpha-1,6-mannosyltransferase that initiates outer chain synthesis. Glycobiology (1994) 0.84

Occurrence of a beta-D-mannopyranosyl phosphate residue in the polyprenyl mannosyl phosphate formed in calf pancreas microsomes and in human lymphocytes. FEBS Lett (1974) 0.84

Differentiation-associated decrease in the proportion of fucosylated polylactosaminoglycans of CaCo-2 human colonic adenocarcinoma cells. Biochem J (1987) 0.84

Graves' disease: a host defense mechanism gone awry. Int Rev Immunol (2000) 0.83

Multiple apomucin translation products from human respiratory mucosa mRNA. Eur J Biochem (1991) 0.83

Changes in cell-surface fucose-containing glycopeptides and adhesion of cultured intestinal epithelial cells as a function of cell density. Biochem J (1983) 0.83

Interaction of the endoplasmic reticulum alpha 1,2-mannosidase Mns1p with Rer1p using the split-ubiquitin system. J Cell Sci (2001) 0.83

Topology of ER processing alpha-mannosidase of Saccharomyces cerevisiae. Glycobiology (1992) 0.82

Inhibition of myoblast fusion by the glucosidase inhibitor N-methyl-1-deoxynojirimycin, but not by the mannosidase inhibitor 1-deoxymannojirimycin. Biochem J (1986) 0.82

Alpha-mannosidases involved in N-glycan processing show cell specificity and distinct subcompartmentalization within the Golgi apparatus of cells in the testis and epididymis. Eur J Cell Biol (1999) 0.81

Biosynthesis of P1-di-N-acetyl-alpha-chitobiosyl P2-dolichyl pyrophosphate in calf pancreas microsomes. J Biol Chem (1978) 0.81

A spectrophotometric assay for alpha-mannosidase activity. Glycobiology (1996) 0.81

Glycoprotein biosynthesis in intestinal epithelial cells during differentiation. Incorporation of [14C]mannose from GDP-[14C]mannose into dolichol derivatives. Biochim Biophys Acta (1980) 0.81

Crystallization and preliminary X-ray analysis of the class 1 alpha 1,2-mannosidase from Saccharomyces cerevisiae. J Struct Biol (1997) 0.80

Molecular cloning, chromosomal mapping and tissue-specific expression of a novel human alpha1,2-mannosidase gene involved in N-glycan maturation. Glycobiology (1998) 0.80

The differential regulation of group II(A) and group V low molecular weight phospholipases A(2) in cultured rat astrocytes. J Biol Chem (2000) 0.80

The Saccharomyces cerevisiae processing alpha 1,2-mannosidase is an inverting glycosidase. Biochem Biophys Res Commun (1995) 0.80

Toxocara infection seroprevalence and its relationship with atopic features in a general adult population. Int Arch Allergy Immunol (2006) 0.79

Production, purification and characterization of recombinant yeast processing alpha 1,2-mannosidase. Glycobiology (1994) 0.79

Biosynthesis of dolichyl phosphate: characterization and site of synthesis in algae. Plant Physiol (1978) 0.79

The synthesis and chemical properties of polyisoprenyl beta-D-mannopyranosyl phosphates. J Biol Chem (1975) 0.79

Characterization of a novel mouse recombinant processing alpha-mannosidase. Glycobiology (1994) 0.78

The transmembrane domain of murine alpha-mannosidase IB is a major determinant of Golgi localization. Eur J Cell Biol (2000) 0.78

Lipid carriers in the synthesis of high-mannose glycoproteins in algae. Biochim Biophys Acta (1979) 0.78

Inhibition of myoblast fusion by bromoconduritol. Biochem Cell Biol (1988) 0.78

Partial characterization of the carbohydrate units of rat intestinal sucrase--isomaltase. Biochem J (1981) 0.78

Mechanism of inhibition of protein glycosylation by the antiviral sugar analogue 2-deoxy-2-fluoro-D-mannose: inhibition of synthesis of man(GlcNAc)2-PP-Dol by the guanosine diphosphate ester. Biochemistry (1985) 0.78

Mutation of Arg(273) to Leu alters the specificity of the yeast N-glycan processing class I alpha1,2-mannosidase. J Biol Chem (2000) 0.77

Two naturally occurring mouse alpha-1,2-mannosidase IB cDNA clones differ in three point mutations. Mutation of Phe592 to Ser592 is sufficient to abolish enzyme activity. J Biol Chem (1995) 0.77

Effects of manno-1-deoxynojirimycin and 2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine on N-linked oligosaccharide processing in intestinal epithelial cells. FEBS Lett (1985) 0.77