Published in Am J Hematol on June 01, 1985
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature (2000) 11.49
Origins of circulating endothelial cells and endothelial outgrowth from blood. J Clin Invest (2000) 5.88
Circulating activated endothelial cells in sickle cell anemia. N Engl J Med (1997) 5.13
Ferritin: a cytoprotective antioxidant strategem of endothelium. J Biol Chem (1992) 4.22
Phagocyte impotence caused by an invasive bacterial adenylate cyclase. Science (1982) 4.10
Iron-catalyzed hydroxyl radical formation. Stringent requirement for free iron coordination site. J Biol Chem (1984) 2.86
Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage. Proc Natl Acad Sci U S A (1993) 2.77
Measuring circulating cell-derived microparticles. J Thromb Haemost (2004) 2.61
Hypoxia/reoxygenation causes inflammatory response in transgenic sickle mice but not in normal mice. J Clin Invest (2000) 2.47
Generation of hydroxyl radical by enzymes, chemicals, and human phagocytes in vitro. Detection with the anti-inflammatory agent, dimethyl sulfoxide. J Clin Invest (1979) 2.40
Abnormal adherence of sickle erythrocytes to cultured vascular endothelium: possible mechanism for microvascular occlusion in sickle cell disease. J Clin Invest (1980) 2.34
The relative magnitudes of endothelial force generation and matrix stiffness modulate capillary morphogenesis in vitro. Exp Cell Res (2004) 2.25
Haptoglobin: a natural bacteriostat. Science (1982) 2.23
Hemoglobin. A biologic fenton reagent. J Biol Chem (1984) 2.16
Erythrocyte adherence to endothelium in sickle-cell anemia. A possible determinant of disease severity. N Engl J Med (1980) 2.14
Activated monocytes in sickle cell disease: potential role in the activation of vascular endothelium and vaso-occlusion. Blood (2000) 2.10
Multicellular oxidant defense in unicellular organisms. Proc Natl Acad Sci U S A (1992) 2.09
Fibrin(ogen) mediates acute inflammatory responses to biomaterials. J Exp Med (1993) 2.09
Mast cells mediate acute inflammatory responses to implanted biomaterials. Proc Natl Acad Sci U S A (1998) 2.02
Hereditary spherocytosis associated with deletion of human erythrocyte ankyrin gene on chromosome 8. Nature (1990) 1.99
Elevated erythrocyte calcium in sickle cell disease. Nature (1973) 1.97
Spontaneous oxygen radical generation by sickle erythrocytes. J Clin Invest (1982) 1.93
Hereditary catalase deficiencies and increased risk of diabetes. Lancet (2000) 1.93
VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling. Exp Cell Res (1999) 1.91
Inflammatory responses to biomaterials. Am J Clin Pathol (1995) 1.89
Molecular basis of biomaterial-mediated foreign body reactions. Blood (2001) 1.87
Superoxide dismutase-rich bacteria. Paradoxical increase in oxidant toxicity. J Biol Chem (1987) 1.78
Phytic acid. A natural antioxidant. J Biol Chem (1987) 1.75
Ras transformation requires metabolic control by 6-phosphofructo-2-kinase. Oncogene (2006) 1.68
Reperfusion injury pathophysiology in sickle transgenic mice. Blood (2000) 1.65
Oxidative stress and induction of heme oxygenase-1 in the kidney in sickle cell disease. Am J Pathol (2001) 1.61
Mechanisms of vascular instability in a transgenic mouse model of sickle cell disease. Am J Physiol Regul Integr Comp Physiol (2000) 1.60
CD36-positive stress reticulocytosis in sickle cell anemia. J Lab Clin Med (1996) 1.59
Tissue factor expression by endothelial cells in sickle cell anemia. J Clin Invest (1998) 1.58
Antioxidant functions of phytic acid. Free Radic Biol Med (1990) 1.52
The adhesive sickle erythrocyte: cause and consequence of abnormal interactions with endothelium, monocytes/macrophages and model membranes. Clin Haematol (1985) 1.51
Accelerated autoxidation and heme loss due to instability of sickle hemoglobin. Proc Natl Acad Sci U S A (1988) 1.51
Hemin: a possible physiological mediator of low density lipoprotein oxidation and endothelial injury. Arterioscler Thromb (1991) 1.49
Chlorinated urban water: a cause of dialysis-induced hemolytic anemia. Science (1973) 1.49
Hemodialysis reduces inhibitory effect of plasma ultrafiltrate on LDL oxidation and subsequent endothelial reactions. Kidney Int (2006) 1.46
Skin color and nutrient photolysis: an evolutionary hypothesis. Science (1978) 1.43
alpha-Ketoacids scavenge H2O2 in vitro and in vivo and reduce menadione-induced DNA injury and cytotoxicity. Am J Physiol (1995) 1.38
Molecular determinants of acute inflammatory responses to biomaterials. J Clin Invest (1996) 1.36
Natural responses to unnatural materials: A molecular mechanism for foreign body reactions. Mol Med (1999) 1.34
Intracellular targets in heme protein-induced renal injury. Kidney Int (1998) 1.33
Bacterial glutathione: a sacrificial defense against chlorine compounds. J Bacteriol (1996) 1.31
Lysosomal involvement in apoptosis. Redox Rep (2001) 1.31
Binding and displacement of vascular endothelial growth factor (VEGF) by thrombospondin: effect on human microvascular endothelial cell proliferation and angiogenesis. Angiogenesis (1999) 1.31
Malaria parasites adopt host cell superoxide dismutase. Science (1983) 1.30
Inflammatory responses to implanted polymeric biomaterials: role of surface-adsorbed immunoglobulin G. J Lab Clin Med (1993) 1.30
The relationship between red cell 2,3-diphosphoglycerate and levels of hemoglobin in the human. Proc Natl Acad Sci U S A (1968) 1.30
Selective inhibition of choline kinase simultaneously attenuates MAPK and PI3K/AKT signaling. Oncogene (2009) 1.28
Membrane abnormalities of irreversibly sickled cells. Semin Hematol (1979) 1.27
Erythrocyte catalase. A somatic oxidant defense? J Clin Invest (1986) 1.24
Thrombospondin mediates adherence of CD36+ sickle reticulocytes to endothelial cells. Blood (1992) 1.24
Phagocytosis of sickle erythrocytes: immunologic and oxidative determinants of hemolytic anemia. Blood (1984) 1.23
A central role for plasminogen in the inflammatory response to biomaterials. J Thromb Haemost (2004) 1.22
Influence of treatment and response status on infection risk in multiple myeloma. Am J Med (1981) 1.21
Hemoglobin potentiates central nervous system damage. J Clin Invest (1987) 1.19
Survival at extreme altitude: protective effect of increased hemoglobin-oxygen affinity. Science (1974) 1.19
Modulation of endothelial cell activation in sickle cell disease: a pilot study. Blood (2001) 1.17
Auto-oxidation and a membrane-associated 'Fenton reagent': a possible explanation for development of membrane lesions in sickle erythrocytes. Clin Haematol (1985) 1.16
Hemoglobin-mediated oxidant damage to the central nervous system requires endogenous ascorbate. J Clin Invest (1988) 1.15
Iron loading of endothelial cells augments oxidant damage. J Lab Clin Med (1990) 1.15
Clinical diversity of sickle cell anemia: genetic and cellular modulation of disease severity. Am J Hematol (1983) 1.14
Abnormal redox status of membrane-protein thiols in sickle erythrocytes. J Clin Invest (1985) 1.14
Hydroxyl radical formation by sickle erythrocyte membranes: role of pathologic iron deposits and cytoplasmic reducing agents. Blood (1991) 1.14
Leishmanial superoxide dismutase: a possible target for chemotherapy. Biochem Biophys Res Commun (1981) 1.13
Degradation of biomaterials by phagocyte-derived oxidants. J Clin Invest (1993) 1.13
Heme and the vasculature: an oxidative hazard that induces antioxidant defenses in the endothelium. Artif Cells Blood Substit Immobil Biotechnol (1994) 1.13
Blood cell abnormalities complicating the hypophosphatemia of hyperalimentation: erythrocyte and platelet ATP deficiency associated with hemolytic anemia and bleeding in hyperalimented dogs. J Lab Clin Med (1974) 1.12
Catalase activity and red cell metabolism. Adv Exp Med Biol (1972) 1.11
Effect of excess alpha-hemoglobin chains on cellular and membrane oxidation in model beta-thalassemic erythrocytes. J Clin Invest (1993) 1.11
Differential endothelial cell gene expression by African Americans versus Caucasian Americans: a possible contribution to health disparity in vascular disease and cancer. BMC Med (2011) 1.11
Cerebral ischemia enhances polyamine oxidation: identification of enzymatically formed 3-aminopropanal as an endogenous mediator of neuronal and glial cell death. J Exp Med (1998) 1.10
Bordetella adenylate cyclase toxin: entry of bacterial adenylate cyclase into mammalian cells. Adv Cyclic Nucleotide Protein Phosphorylation Res (1984) 1.10
Hypohaptoglobinemia associated with familial epilepsy. J Exp Med (1985) 1.10
Antimalarial properties of orally active iron chelators. Blood (1988) 1.09
Superoxide dismutase amplifies organismal sensitivity to ionizing radiation. J Biol Chem (1989) 1.08
Host heme catabolism in drug-sensitive and drug-resistant malaria. J Lab Clin Med (1977) 1.08
Iron-containing superoxide dismutase from Crithidia fasciculata. Purification, characterization, and similarity to Leishmanial and trypanosomal enzymes. J Biol Chem (1983) 1.08
Human llamas: adaptation to altitude in subjects with high hemoglobin oxygen affinity. J Clin Invest (1978) 1.08
A novel technique for culture of human dermal microvascular endothelial cells under either serum-free or serum-supplemented conditions: isolation by panning and stimulation with vascular endothelial growth factor. Exp Cell Res (1997) 1.07
Pathobiology of heme interaction with the erythrocyte membrane. Semin Hematol (1989) 1.07
Hemolysis in dialized patients caused by chloramines. Nephron (1974) 1.07
Chemical camouflage of antigenic determinants: stealth erythrocytes. Proc Natl Acad Sci U S A (1997) 1.06
Comparison of the antianginal effectiveness of nifedipine, verapamil, and isosorbide dinitrate in patients receiving propranolol: a double-blind study. Circulation (1983) 1.06
Calcium-induced damage of haemoglobin SS and normal erythrocytes. Br J Haematol (1978) 1.06
Inhibition of phagocyte-endothelium interactions by oxidized fatty acids: a natural anti-inflammatory mechanism? J Lab Clin Med (1996) 1.05
Role of red cell 2,3-diphosphoglycerate in the adaptation of man to altitude. J Lab Clin Med (1969) 1.05
Influence of the ionophore A23187 on the plastic behavior of normal erythrocytes. Am J Pathol (1977) 1.03
Disturbance of plasma and platelet thrombospondin levels in sickle cell disease. Am J Hematol (1996) 1.03
Apoptotic death of inflammatory cells in human atheroma. Arterioscler Thromb Vasc Biol (2001) 1.03
Nucleosomal histone protein protects DNA from iron-mediated damage. Nucleic Acids Res (1992) 1.03
Delayed oxidant-induced cell death involves activation of phospholipase A2. FEBS Lett (2001) 1.01
Synergistic effects of oxidation and deformation on erythrocyte monovalent cation leak. Blood (1990) 1.00