Published in J Physiol on November 01, 1978
The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc Natl Acad Sci U S A (1986) 3.97
The biological conversion of 7-dehydrocholesterol into cholesterol and comments on the reduction of double bonds. Biochem J (1968) 3.36
The novel anticonvulsant drug, gabapentin (Neurontin), binds to the alpha2delta subunit of a calcium channel. J Biol Chem (1996) 3.26
7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-D-aspartate receptor complex. Proc Natl Acad Sci U S A (1988) 1.99
Dopamine receptors in rat striatum and nucleus accumbens; conformational studies using rigid analogues of dopamine. J Pharm Pharmacol (1977) 1.95
The pharmacology of Helix dopamine receptor of specific neurones in the snail, Helix aspersa. Comp Biochem Physiol (1968) 1.85
Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity. Proc Natl Acad Sci U S A (1990) 1.82
Structural requirements for binding to the sugar-transport system of the human erythrocyte. Biochem J (1973) 1.73
The status of C-6, C-7, C-15 and C-16 hydrogen atoms in cholesterol biosynthesis. Eur J Biochem (1969) 1.56
The formation and reduction of the 14,15-double bond in cholesterol biosynthesis. Biochem J (1971) 1.50
Studies on the behavioural pharmacology of a cyclic analogue of dopamine following its injection into the brains of conscious rats. Br J Pharmacol (1975) 1.46
Autoradiographic localization and biochemical characterization of peripheral type CCK receptors in rat CNS using highly selective nonpeptide CCK antagonists. J Neurosci (1987) 1.46
Enzymic hydrolysis of the carbon-fluorine bond of alpha-D-glucosyl fluoride by rat intestinal mucosa. Localization of intestinal maltase. Biochem J (1967) 1.45
Studies on the pharmacology of neurones in the nucleus accumbens of the rat. Brain Res (1976) 1.43
Evidence for two asymmetric conformational states in the human erythrocyte sugar-transport system. Biochem J (1975) 1.38
Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil. J Neurosci (1987) 1.38
Dopamine receptors: a review. Comp Gen Pharmacol (1971) 1.37
Problems associated with iontophoretic studies in the caudate nucleus and substantia nigra. Neuropharmacology (1974) 1.37
The hydrolysis of glycosyl fluorides by glycosidases. Biochem J (1967) 1.36
Light microscopic autoradiographic localisation of [3H]glycine and [3H]strychnine binding sites in rat brain. Eur J Pharmacol (1986) 1.31
The effect of dopamine and other compounds on the activity of neurones of Helix aspersa; structure-activity relationships. Int J Neuropharmacol (1969) 1.31
The antiepileptic agent gabapentin (Neurontin) possesses anxiolytic-like and antinociceptive actions that are reversed by D-serine. Psychopharmacology (Berl) (1996) 1.27
Structural requirements for active intestinal transport. Spatial and bonding requirements at C-3 of the sugar. Biochem J (1969) 1.23
Presynaptic gamma-aminobutyric acid receptors in the rat anococcygeus muscle and their antagonism by 5-aminovaleric acid. Br J Pharmacol (1982) 1.22
The effect of angiotensin on rat intestinal fluid transfer. J Endocrinol (1970) 1.20
Angiotensin II in central nervous system physiology. Regul Pept (1998) 1.18
The angiotensin II type 2 receptor: an enigma with multiple variations. Am J Physiol Endocrinol Metab (2000) 1.18
Factors affecting mucosal water and sodium transfer in everted sacs of rat jejunum. J Physiol (1969) 1.18
The role of a cholesta-8,14-dien-3-beta-ol system in cholesterol biosynthesis. Biochem J (1969) 1.17
Effects of angiotensin II on fluid transport, transmural potential difference and blood flow by rat jejunum in vivo. J Physiol (1975) 1.16
The effect of the renin-angiotensin system on mucosal water and sodium transfer in everted sacs of rat jejunum. J Physiol (1970) 1.15
Chemical composition of an oestrogen-induced calcium-binding glycolipophosphoprotein in Xenopus laevis. Biochem J (1971) 1.14
Characterisation of [3H]gabapentin binding to a novel site in rat brain: homogenate binding studies. Eur J Pharmacol (1993) 1.12
Oxygen and glucose deprivation-induced neuronal apoptosis is attenuated by halothane and isoflurane. Anesth Analg (2001) 1.11
[3H]MK-801 labels a site on the N-methyl-D-aspartate receptor channel complex in rat brain membranes. J Neurochem (1988) 1.11
Effects of antidepressant drugs on noradrenaline accumulation and contractile responses in the rat anococcygeus muscle. Br J Pharmacol (1977) 1.10
Oestrogen-induced calcium-binding protein in Xenopus laevis. Biochim Biophys Acta (1968) 1.09
Mitogen-activated protein kinases in rat brain neuronal cultures are activated by angiotensin II type 1 receptors and inhibited by angiotensin II type 2 receptors. J Biol Chem (1996) 1.07
Structural requirements for active intestinal sugar transport. The involvement of hydrogen bonds at C-1 and C-6 of the sugar. Biochem J (1968) 1.07
MK-801 is neuroprotective in gerbils when administered during the post-ischaemic period. Neuroscience (1988) 1.07
Changes in renal blood flow and PAH extraction during extracorporeal circulation of short and long duration. Experimental study in dogs. Cardiovasc Res (1969) 1.07
Studies on the induction and biosynthesis of vitellogenin, an oestrogen-induced glycolipophosphoprotein. Biochem J (1971) 1.07
The uptake and release of [3-H]-2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthlane (ADTN) by striatal nerve terminals. Br J Pharmacol (1978) 1.06
Functional interactions between neuronal AT1 and AT2 receptors. Endocrinology (1997) 1.06
Evidence for an involvement of the brain cholecystokinin B receptor in anxiety. Proc Natl Acad Sci U S A (1991) 1.06
Structural requirements for active intestinal transport. The nature of the carrier-sugar bonding at C-2 and the ring oxygen of the sugar. Biochem J (1970) 1.05
Angiotensin II type 2 receptor-modulated changes in potassium currents in cultured neurons. Am J Physiol (1993) 1.03
Pharmacology of a cholecystokinin receptor on 5-hydroxytryptamine neurones in the dorsal raphe of the rat brain. Br J Pharmacol (1991) 1.02
Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation. J Neurosci (1988) 1.01
Species differences in the localization of 'peripheral' type cholecystokinin receptors in rodent brain. Neurosci Lett (1987) 1.01
Quantitative evaluation of the potencies of GABA-receptor agonists and antagonists using the rat hippocampal slice preparation. Br J Pharmacol (1986) 1.01
Ethanol inhibits NMDA receptor-mediated excitotoxicity in rat primary neuronal cultures. Alcohol Clin Exp Res (1993) 1.01
[3H]gabapentin may label a system-L-like neutral amino acid carrier in brain. Eur J Pharmacol (1993) 1.00
Response of rat jejunum to angiotensin II: role of norepinephrine and prostaglandins. Am J Physiol (1981) 1.00
Rationally designed "dipeptoid" analogues of CCK. alpha-Methyltryptophan derivatives as highly selective and orally active gastrin and CCK-B antagonists with potent anxiolytic properties. J Med Chem (1991) 1.00
Autoradiographical detection of cholecystokinin-A receptors in primate brain using 125I-Bolton Hunter CCK-8 and 3H-MK-329. J Neurosci (1990) 1.00
Chronic ethanol exposure potentiates NMDA excitotoxicity in cerebral cortical neurons. J Neurochem (1993) 1.00
Angiotensin II type 1 receptor mRNA levels in the brains of normotensive and spontaneously hypertensive rats. J Neurochem (1993) 1.00
Proceedings: Increase in the cyclic AMP content of rat striatum produced by a cyclic analogue of dopamine. J Physiol (1974) 0.99
Further evidence for the stimulation of rat brain dopamine receptors by a cyclic analogue of dopamine. J Pharm Pharmacol (1974) 0.99
An explanation of the asymmetric binding of sugars to the human erythrocyte sugar-transport systems. Biochem J (1973) 0.99
The interaction of the NK1 receptor antagonist CP-96,345 with L-type calcium channels and its functional consequences. Br J Pharmacol (1993) 0.98
The effect of angiotensin on cation transport by rat kidney cortex slices. J Physiol (1971) 0.98
The effect of ibotenic acid and muscimol on single neurons of the snail, Helix aspersa. Comp Gen Pharmacol (1971) 0.98
Studies on amino acid receptors from neurones of Helix aspersa. J Physiol (1973) 0.97
Antagonism of responses to excitatory amino acids on rat cortical neurones by the spider toxin, argiotoxin636. Br J Pharmacol (1989) 0.97
The binding of [125I]-angiotensin to rat renal epithelial cell membranes. Br J Pharmacol (1983) 0.96
The behavioural properties of CI-988, a selective cholecystokininB receptor antagonist. Br J Pharmacol (1991) 0.96
Aldosterone and angiotensin action on water absorption in the rat jejunum. J Physiol (1967) 0.96
Protective effect of the glutamate antagonist, MK-801 in focal cerebral ischemia in the cat. J Cereb Blood Flow Metab (1988) 0.96
Effect of exercise training on blood pressure in 70- to 79-yr-old men and women. Med Sci Sports Exerc (1991) 0.95
Studies on the mechanism of action of angiotensin on fluid transport by the mucosa of rat distal colon. J Endocrinol (1972) 0.95
The affinities, potencies and efficacies of some benzodiazepine-receptor agonists, antagonists and inverse-agonists at rat hippocampal GABAA-receptors. Br J Pharmacol (1987) 0.95
ANG II-mediated inhibition of neuronal delayed rectifier K+ current: role of protein kinase C-alpha. Am J Physiol Cell Physiol (2001) 0.95
Differentiation of central cholecystokinin receptor binding sites using the non-peptide antagonists MK-329 and L-365,260. Brain Res (1990) 0.95
The effect of neuroleptic drugs on drinking induced by central administration of angiotensin or carbachol. Psychopharmacology (Berl) (1979) 0.95
Influence of sodium and sulphydryl groups on [3H]sulpiride binding sites in rat striatal membranes. J Neurochem (1982) 0.94
Location of [125I]-angiotensin II receptors on rat kidney cortex epithelial cells. Br J Pharmacol (1984) 0.94
Noradrenaline as a possible mediator of the actions of angiotensin on fluid transport by rat jejunum in vivo. J Physiol (1979) 0.94
Increased angiotensin II receptors in neuronal cultures from hypertensive rat brain. Am J Physiol (1984) 0.94
The actions of dopamine and of sulpiride on regional blood flows in the rat kidney. J Physiol (1980) 0.94
The pathway for the conversion of dihydroagnosterol into cholesterol in rat liver. Biochem J (1977) 0.94
Effect of the (+)-and (-)-enantiomers of sulpiride on ADTN-induced hyperactivity in the rat [proceedings]. Br J Pharmacol (1978) 0.93
Impaired glutamatergic synaptic transmission in the PKU brain. Mol Genet Metab (2005) 0.93
The effect of bicuculline on the gamma-aminobutyric acid (GABA) receptors of neurons of Periplaneta americana and Helix aspersa. Brain Res (1971) 0.93
Chronic ethanol increases N-methyl-D-aspartate-stimulated nitric oxide formation but not receptor density in cultured cortical neurons. Mol Pharmacol (1997) 0.93
Angiotensin II type 2 receptor stimulation of neuronal K+ currents involves an inhibitory GTP binding protein. Am J Physiol (1994) 0.93
Studies on polyol function in Aspergillus clavatus: a role for mannitol and ribitol. J Gen Microbiol (1971) 0.92
The anticonvulsant action of CI-977, a selective kappa-opioid receptor agonist: a possible involvement of the glycine/NMDA receptor complex. Eur J Pharmacol (1990) 0.92
The selective NK3 receptor agonist senktide excites a subpopulation of dopamine-sensitive neurones in the rat substantia nigra pars compacta in vitro. Br J Pharmacol (1992) 0.92
Localization of [3H]gabapentin to a novel site in rat brain: autoradiographic studies. Eur J Pharmacol (1993) 0.92
Active and inactive renin release from rabbit kidney cortex slices: effect of sodium concentration and of furosemide. J Physiol (1982) 0.92
Studies on the biosynthesis of tetrahymanol in Tetrahymena pyriformis. The mechanism of inhibition by cholesterol. Biochem J (1974) 0.92
Binding of [3H]sulpiride to purified rat striatal synaptic membranes. Neuroscience (1981) 0.92
Increased angiotensin II type-1 receptor gene expression in neuronal cultures from spontaneously hypertensive rats. Endocrinology (1993) 0.92
Polyamines potentiate NMDA induced whole-cell currents in cultured striatal neurons. Eur J Pharmacol (1990) 0.91
Agonists selective for tachykinin NK1 and NK3 receptors excite subpopulations of neurons in the rat medial habenula nucleus in vitro. Eur J Pharmacol (1993) 0.91