Published in J Physiol on September 01, 1988
Hyperalgesic agents increase a tetrodotoxin-resistant Na+ current in nociceptors. Proc Natl Acad Sci U S A (1996) 2.84
Capnellene, a natural marine compound derived from soft coral, attenuates chronic constriction injury-induced neuropathic pain in rats. Br J Pharmacol (2009) 1.82
Electrophysiological differences between nociceptive and non-nociceptive dorsal root ganglion neurones in the rat in vivo. J Physiol (2005) 1.73
The functions of TRPA1 and TRPV1: moving away from sensory nerves. Br J Pharmacol (2012) 1.69
Association of Joint Inflammation With Pain Sensitization in Knee Osteoarthritis: The Multicenter Osteoarthritis Study. Arthritis Rheumatol (2016) 1.49
Arthritis and pain. Neurogenic origin of joint pain. Arthritis Res Ther (2006) 1.21
Unresponsive afferent nerve fibres in the sural nerve of the rat. J Physiol (1991) 1.17
Distinct sensitizing effects of the cAMP-PKA second messenger cascade on rat dural mechanonociceptors. J Physiol (2002) 1.13
Sensitivity and sensitisation in relation to pain severity in knee osteoarthritis: trait or state? Ann Rheum Dis (2013) 1.04
Distribution of neurofilament-positive nerve fibres and sensory endings in the human anterior cruciate ligament. Arch Orthop Trauma Surg (1995) 0.95
The role of PKA and PKCepsilon pathways in prostaglandin E2-mediated hypernociception. Br J Pharmacol (2009) 0.91
The science of migraine. J Vestib Res (2011) 0.91
Intraplantar PGE2 causes nociceptive behaviour and mechanical allodynia: the role of prostanoid E receptors and protein kinases. Br J Pharmacol (2007) 0.90
Evaluation of long-term antinociceptive properties of stabilized hyaluronic acid preparation (NASHA) in an animal model of repetitive joint pain. Arthritis Res Ther (2011) 0.86
Intraplantar-injected ceramide in rats induces hyperalgesia through an NF-κB- and p38 kinase-dependent cyclooxygenase 2/prostaglandin E2 pathway. FASEB J (2011) 0.85
Role of neurogenic inflammation in pancreatitis and pancreatic pain. Neurosignals (2005) 0.83
Prostaglandin E2 increases the expression of the neurokinin1 receptor in adult sensory neurones in culture: a novel role of prostaglandins. Br J Pharmacol (2003) 0.82
Calcitonin gene-related peptide receptor antagonists: beyond migraine pain--a possible analgesic strategy for osteoarthritis? Curr Pain Headache Rep (2013) 0.81
Acidosis Mediates the Switching of Gs-PKA and Gi-PKCε Dependence in Prolonged Hyperalgesia Induced by Inflammation. PLoS One (2015) 0.80
Libidibia ferrea mature seeds promote antinociceptive effect by peripheral and central pathway: possible involvement of opioid and cholinergic receptors. Biomed Res Int (2014) 0.76
Efficacy of focused low-intensity pulsed ultrasound therapy for the management of knee osteoarthritis: a randomized, double blind, placebo-controlled trial. Sci Rep (2016) 0.75
Profound alteration in cutaneous primary afferent activity produced by inflammatory mediators. Elife (2016) 0.75
Calcitonin gene-related peptide and pain: a systematic review. J Headache Pain (2017) 0.75
The role of the transient receptor potential ankyrin type-1 (TRPA1) channel in migraine pain: evaluation in an animal model. J Headache Pain (2017) 0.75
[Neurophysiology of nociception and pain in deep tissue (skeletal muscle, tendon, joint, connective tissue).]. Schmerz (1991) 0.75
Spinal cord effects of antipyretic analgesics. Drugs (1994) 0.75
Basic mechanisms of cough: current understanding and remaining questions. Lung (2007) 0.75
Studies on the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine. J Pathol (1971) 6.97
Prostaglandins, aspirin-like drugs and analgesia. Nat New Biol (1972) 4.91
Role of prostaglandin-mediated vasodilatation in inflammation. Nature (1977) 3.95
Prostaglandin E2, prostaglandin I2 and the vascular changes of inflammation. Br J Pharmacol (1979) 3.58
Effects of an experimental arthritis on the sensory properties of fine articular afferent units. J Neurophysiol (1985) 1.81
The hyperalgesic effects of prostacyclin and prostaglandin E2. Prostaglandins (1978) 1.74
Letter: Prostaglandins as regulators of bradykinin responses. J Pharm Pharmacol (1973) 1.54
I - Prostaglandin hyperalgesia, a cAMP/Ca2+ dependent process. Prostaglandins (1979) 1.52
Cutaneous vascular reactions to prostaglandins in healthy subjects and in patients with urticaria and atopic dermatitis. Acta Derm Venereol (1969) 1.51
On the ability of prostaglandin E1, and arachidonic acid to modulate experimentally induced oedema in the rat paw. Br J Pharmacol (1975) 1.45
The role of prostaglandins in rabbit monoarticular arthritis. Br J Pharmacol (1974) 1.40
Inhibition of prostaglandin biosynthesis as the mechanism of analgesia of aspirin-like drugs in the dog knee joint. Eur J Pharmacol (1975) 1.34
The modulation of enhanced vascular permeability by prostaglandins through alterations in blood flow (hyperemia). Agents Actions (1976) 1.31
Sensitization of group IV muscle receptors to bradykinin by 5-hydroxytryptamine and prostaglandin E2. Brain Res (1981) 1.28
Levels of prostaglandins F2 alpha and E2 and thromboxane B2 in joint fluid in rheumatoid arthritis. Scand J Rheumatol (1977) 1.16
The synovial prostaglandin system in chronic inflammatory arthritis: differential effects of steroidal and nonsteroidal anti-inflammatory drugs. Br J Pharmacol (1981) 1.15
Is prostacyclin in the major pro-inflammatory prostanoid in joint fluid? Life Sci (1980) 1.14
Studies on the relative effects of prostaglandins, bradykinin, 5-hydroxytryptamine and histamine on the synovial microcirculation in dogs. Br J Pharmacol (1976) 1.13
Activation of groups III and IV sensory units in medial articular nerve by local mechanical stimulation of knee joint. J Neurophysiol (1983) 1.10
Responses of fine medial articular nerve afferents to passive movements of knee joints. J Neurophysiol (1983) 1.10
The effects of bradykinin and prostaglandin E1 on rat cutaneous afferent nerve activity. Br J Pharmacol (1977) 1.04
Synthesis of arachidonate cyclo-oxygenase products by rheumatoid and nonrheumatoid synovial lining in nonproliferative organ culture. Ann Rheum Dis (1983) 0.96
Prostaglandin E1-induced sensitization of A delta moderate pressure mechanoreceptors. Brain Res (1982) 0.91
Pharmacological modulation of edema mediated by prostaglandin, serotonin and histamine. Agents Actions (1980) 0.88
[Prostaglandins E2 and F2 alpha concentrations in the synovial fluid in rheumatoid and traumatic knee joint diseases]. Z Rheumatol (1980) 0.88
Activation of fine articular afferent units by bradykinin. Brain Res (1985) 0.87
Effects of acetylsalicylic acid and indomethacin on single groups III and IV sensory units from acutely inflamed joints. Pain (1986) 0.80
Transducer action of isolated frog muscle spindle evoked by pseudorandom noise stimuli. J Neurophysiol (1986) 0.78
Presynaptic inhibition in the vertebrate spinal cord revisited. Exp Brain Res (1999) 3.30
Presynaptic inhibition in the vertebrate central nervous system. Ergeb Physiol (1971) 2.24
Facilitation at the frog neuromuscular junction during and after repetitive stimulation. Pflugers Arch Gesamte Physiol Menschen Tiere (1966) 2.09
The effect of acetylcholine upon mammalian motor nerve terminals. J Physiol (1965) 2.07
Potential changes recorded from the frog motor nerve terminal during its activation. Pflugers Arch Gesamte Physiol Menschen Tiere (1966) 2.06
Single unit responses and the total afferent outflow from the cat's foot pad upon mechanical stimulation. Exp Brain Res (1968) 2.04
Responses of group IV afferent units from skeletal muscle to stretch, contraction and chemical stimulation. Exp Brain Res (1978) 1.84
Effects of an experimental arthritis on the sensory properties of fine articular afferent units. J Neurophysiol (1985) 1.81
Nerve fibres and their terminals of the dura mater encephali of the rat. Anat Embryol (Berl) (1987) 1.53
Time course of mechanosensitivity changes in articular afferents during a developing experimental arthritis. J Neurophysiol (1988) 1.52
Somatosympathetic reflexes: afferent fibers, central pathways, discharge characteristics. Physiol Rev (1973) 1.46
Mechanical sensitivity of group III and IV afferents from posterior articular nerve in normal and inflamed cat knee. J Neurophysiol (1986) 1.36
Activation of group IV afferent units from muscle by algesic agents. Brain Res (1974) 1.32
Two specific feedback pathways to the central afferent terminals of phasic and tonic mechanoreceptors. Exp Brain Res (1968) 1.31
Swelling-activated calcium signalling in cultured mouse primary sensory neurons. Eur J Neurosci (2001) 1.23
Afferent and efferent axons in the medial and posterior articular nerves of the cat. Anat Rec (1983) 1.17
Cutaneous mechanoreceptors influencing impulse discharges in cerebellar cortex. 3. In Purkynĕ cells by climbing fiber input. Exp Brain Res (1972) 1.16
Opiates inhibit the discharges of fine afferent units from inflamed knee joint of the cat. Neurosci Lett (1987) 1.11
Activation of groups III and IV sensory units in medial articular nerve by local mechanical stimulation of knee joint. J Neurophysiol (1983) 1.10
The impact of somatosensory input on autonomic functions. Rev Physiol Biochem Pharmacol (1997) 1.10
Responses of fine medial articular nerve afferents to passive movements of knee joints. J Neurophysiol (1983) 1.10
Discharge characteristics of fine medial articular afferents at rest and during passive movements of inflamed knee joints. Brain Res (1983) 1.08
Integration by Purkynĕ cells of mossy and climbing fiber inputs from cutaneous mechanoreceptors. Exp Brain Res (1972) 1.07
Increase of meningeal blood flow after electrical stimulation of rat dura mater encephali: mediation by calcitonin gene-related peptide. Br J Pharmacol (1995) 1.07
Presynaptic depolarization of cutaneous mechanoreceptor afferents after mechanical skin stimulation. Exp Brain Res (1967) 1.05
[Effect of diazepam on presynaptic inhibition and other spinal reflexes]. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol (1967) 1.04
Changes in tonic descending inhibition of spinal neurons with articular input during the development of acute arthritis in the cat. J Neurophysiol (1991) 1.03
Sensory innervation of the Achilles tendon by group III and IV afferent fibers. Anat Embryol (Berl) (1985) 1.02
Effects of mechanical and chemical stimulation of fine muscle afferents upon primate spinothalamic tract cells. J Physiol (1979) 1.02
Intra-articular injections of hyaluronan solutions of different elastoviscosity reduce nociceptive nerve activity in a model of osteoarthritic knee joint of the guinea pig. Osteoarthritis Cartilage (2008) 1.01
Elastoviscous substances with analgesic effects on joint pain reduce stretch-activated ion channel activity in vitro. Pain (2002) 1.00
Enhancement of the responses of ascending tract cells in the cat spinal cord by acute inflammation of the knee joint. Exp Brain Res (1987) 0.99
Heart rate changes reflecting modifications of efferent cardiac sympathetic outflow by cutaneous and muscle afferent volleys. J Auton Nerv Syst (1981) 0.99
Innervation of the dura mater encephali of cat and rat: ultrastructure and calcitonin gene-related peptide-like and substance P-like immunoreactivity. Anat Embryol (Berl) (1993) 0.98
Cutaneous convergence on to the climbing fibre input to cerebellar Purkynĕ cells. J Physiol (1973) 0.98
Changes in extracellular potassium concentration in cat spinal cord in response to innocuous and noxious stimulation of legs with healthy and inflamed knee joints. Exp Brain Res (1990) 0.98
Reflex bladder activity induced by electrical stimulation of hind limb somatic afferents in the cat. J Auton Nerv Syst (1980) 0.96
Spinal and supraspinal components of the reflex discharges into lumbar and thoracic white rami. J Physiol (1971) 0.96
The spinocervical tract as a possible pathway for muscular nociception. J Physiol (Paris) (1977) 0.95
Sensitization of articular afferents to mechanical stimuli by bradykinin. Pflugers Arch (1989) 0.95
Convergent inputs from articular, cutaneous and muscle receptors onto ascending tract cells in the cat spinal cord. Exp Brain Res (1987) 0.94
Cutaneous mechanoreceptors influencing impulse discharges in cerebellar cortex. II. In Purkynĕ cells by mossy fiber input. Exp Brain Res (1972) 0.94
Field potentials and excitation of primate spinothalamic neurones in response to volleys in muscle afferents. J Physiol (1979) 0.94
An analysis of the reflex activity in the cervical sympathetic trunk induced by myelinated somatic afferents. Pflugers Arch (1970) 0.94
Cortical and peripheral modification of cerebellar climbing fibre activity arising from cutaneous mechanoreceptors. J Physiol (1973) 0.93
Inflammatory mediators and nociception in the joint: excitation and sensitization of slowly conducting afferent fibers of cat's knee by prostaglandin I2. Neuroscience (1992) 0.91
An electron microscopic analysis of the left phrenic nerve in the rat. Anat Rec (1983) 0.90
Cerebellar Purkynĕ cell responses to cutaneous mechanoreceptors. Brain Res (1971) 0.89
The effects of phorbol ester on slowly conducting afferents of the cat's knee joint. Exp Brain Res (1993) 0.89
The modulation of visceral functions by somatic afferent activity. Jpn J Physiol (1987) 0.89
Activation of normal and inflamed fine articular afferent units by serotonin. Pain (1992) 0.89
Tonic descending inhibition of spinal cord neurones driven by joint afferents in normal cats and in cats with an inflamed knee joint. Exp Brain Res (1991) 0.88
Calcitonin gene related peptide released from dural nerve fibers mediates increase of meningeal blood flow in the rat. Can J Physiol Pharmacol (1995) 0.87
Fiber size distribution of myelinated and unmyelinated axons in the medial and posterior articular nerves of the cat's knee joint. Somatosens Res (1988) 0.87
Activation of fine articular afferent units by bradykinin. Brain Res (1985) 0.87
Involvement of nitric oxide in the modulation of dural arterial blood flow in the rat. Br J Pharmacol (2000) 0.86
Joint receptors and kinaesthesia. Exp Brain Res (1988) 0.86
Ultrastructural three-dimensional reconstruction of group III and group IV sensory nerve endings ("free nerve endings") in the knee joint capsule of the cat: evidence for multiple receptive sites. J Comp Neurol (1990) 0.86
Responses of spinal cord neurones to stimulation of articular afferent fibres in the cat. J Physiol (1986) 0.86
Excitability measurements at the central terminals of single mechano-receptor afferents during slow potential changes. Exp Brain Res (1967) 0.86
Types of afferents from the knee joint evoking sympathetic reflexes in cat inferior cardiac nerves. Neurosci Lett (1983) 0.86
Mitochondria in fine afferent nerve fibres of the knee joint in the cat: a quantitative electron-microscopical examination. Cell Tissue Res (1994) 0.86
Effects of the 5-HT1 receptor agonists, sumatriptan and CP 93,129, on dural arterial flow in the rat. Eur J Pharmacol (1997) 0.85
Descending influences on the responses of spinocervical tract neurones to chemical stimulation of fine muscle afferents. J Physiol (1979) 0.85
Reflex activity in the cervical and lumbar sympathetic trunk induced by unmyelinated somatic afferents. Brain Res (1970) 0.85
Somatotopic studies on the vermal cortex of the cerebellar anterior lobe of unanaesthetized cats. Exp Brain Res (1977) 0.85
Dorsal root potentials evoked by natural stimulation of cutaneous afferents. Nature (1966) 0.84
Peripheral modulation of rat knee joint afferent mechanosensitivity by nociceptin/orphanin FQ. Neurosci Lett (2000) 0.84
Changes in blood pressure and heart rate induced by movements of normal and inflamed knee joints. Neurosci Lett (1984) 0.84
Three-dimensional reconstruction of scleral cold thermoreceptors of the cat eye. J Comp Neurol (2001) 0.83
Muscle receptors with fine afferent fibers which may evoke circulatory reflexes. Circ Res (1981) 0.83
Single unit responses in the cervical sympathetic trunk upon somatic nerve stimulation. Pflugers Arch (1970) 0.83
Muscle and cutaneous afferents evoking sympathetic reflexes. Brain Res (1966) 0.83
Depending on the mode of application morphine enhances or depresses somatocardiac sympathetic A- and C-reflexes in anesthetized rats. Neurosci Res (1992) 0.82
Projections of primary afferent fibres from muscle to neurones of the spinocervical tract of the cat. J Physiol (1978) 0.82
An intact nerve preparation for monitoring inputs from single joint afferent fibres. J Neurosci Methods (1995) 0.82
Cutaneous mechanoreceptors influencing impulse discharges in cerebellar cortex. I. In mossy fibers. Exp Brain Res (1972) 0.82
Reflexes in postganglionic cutaneous fibres by stimulation of group I to group IV somatic afferents. Pflugers Arch (1972) 0.81
Participation of NK1 receptors in nociceptin-induced modulation of rat knee joint mechanosensitivity. Exp Brain Res (2001) 0.81
Cortical projection of the rat knee joint innervation and its processing in the somatosensory areas SI and SII. Exp Brain Res (2001) 0.81
Presynaptic depolarization during activation of tonic mechanoreceptors. Brain Res (1967) 0.81
Mode of operation of the cerebellum in the dynamic loop control of movement. Brain Res (1972) 0.81
Ganglionic transmission of somatically induced sympathetic reflexes. Pflugers Arch (1971) 0.81
Substance P- and calcitonin gene-related peptide immunoreactivity in primary afferent neurons of the cat's knee joint. Neuroscience (1991) 0.81
Primary afferent depolarization of muscle afferents elicited by stimulation of joint afferents in cats with intact neuraxis and during reversible spinalization. J Neurophysiol (1993) 0.80
Reactions of cardiac postganglionic sympathetic neurons to movements of normal and inflamed knee joints. J Auton Nerv Syst (1985) 0.80
Response properties of thick myelinated group II afferents in the medial articular nerve of normal and inflamed knee joints of the cat. Somatosens Mot Res (1991) 0.80
[Correlation of scintigraphic and x-ray findings in Marie-Bamberger secondary hypertrophic osteoarthropathy]. Rofo (1986) 0.80
Somato-vesical reflexes in chronic spinal cats. J Auton Nerv Syst (1983) 0.80
Convergence of muscle and cutaneous input onto primate spinothalamic tract neurons. Brain Res (1977) 0.80
Quantification of cat's articular afferents containing calcitonin gene-related peptide or substance P innervating normal and acutely inflamed knee joints. Neurosci Lett (1997) 0.80
Effects of acetylsalicylic acid and indomethacin on single groups III and IV sensory units from acutely inflamed joints. Pain (1986) 0.80
Inhibition of cerebellar climbing fibre activity by stimulation of precruciate cortex. Brain Res (1972) 0.80
Sensitisation of group III articular afferents to mechanical stimuli by substance P. Inflamm Res (2001) 0.79
Responsiveness of slowly conducting articular afferents to bradykinin: effects of an experimental arthritis. Pain (1994) 0.79
Small reduction of capsaicin-induced neurogenic inflammation in human forearm skin by the glucocorticoid prednicarbate. Agents Actions (1993) 0.79
Responses of lateral thalamic neurons to algesic chemical stimulation of the cat knee joint. Exp Brain Res (1994) 0.79
Cyclooxygenase inhibitors acetylsalicylic acid and indomethacin do not affect capsaicin-induced neurogenic inflammation in human skin. Agents Actions (1993) 0.79
Spinal cord afferents: functional organization and inhibitory control. UCLA Forum Med Sci (1969) 0.79
Parallel organization of proprioceptive inputs from joint receptors to cortical somatosensory areas I and II in the cat. J Physiol (1996) 0.78