PubRank

L Varticovski

Author PubWeight™ 36.58‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells. Science 1988 2.29
2 Hypoxia induces vascular endothelial growth factor in cultured human endothelial cells. J Biol Chem 1995 2.20
3 Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression. J Clin Invest 1996 1.82
4 Phosphatidylinositol 3-kinase and its novel product, phosphatidylinositol 3-phosphate, are present in Saccharomyces cerevisiae. J Biol Chem 1989 1.53
5 The src homology 2 domain of Bcr/Abl is required for efficient induction of chronic myeloid leukemia-like disease in mice but not for lymphoid leukemogenesis or activation of phosphatidylinositol 3-kinase. Blood 2001 1.47
6 In vitro evidence that myocardial ischemia resulting from 5-fluorouracil chemotherapy is due to protein kinase C-mediated vasoconstriction of vascular smooth muscle. Cancer Res 1993 1.43
7 Role of PI 3-kinase in angiopoietin-1-mediated migration and attachment-dependent survival of endothelial cells. Exp Cell Res 1999 1.36
8 Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes. Br J Cancer 2008 1.27
9 Association of phosphatidylinositol 3-kinase with a specific sequence of the T cell receptor zeta chain is dependent on T cell activation. J Biol Chem 1994 1.27
10 Interleukin-2 receptor regulates activation of phosphatidylinositol 3-kinase. J Biol Chem 1991 1.26
11 Molecular characterisation of side population cells with cancer stem cell-like characteristics in small-cell lung cancer. Br J Cancer 2010 1.23
12 Platelet-derived growth factor activates membrane-associated phosphatidylinositol 3-kinase and mediates its translocation from the cytosol. Detection of enzyme activity in detergent-solubilized cell extracts. J Biol Chem 1992 1.18
13 Divergence in signal transduction pathways of platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) receptors. Involvement of sphingosine 1-phosphate in PDGF but not EGF signaling. J Biol Chem 1997 1.10
14 Studies on fenestral contraction in rat liver endothelial cells in culture. Am J Pathol 1996 1.07
15 BCR/abl leads to the constitutive activation of Stat proteins, and shares an epitope with tyrosine phosphorylated Stats. Leukemia 1996 1.02
16 The role of phosphoinositide 3-kinase in taurocholate-induced trafficking of ATP-dependent canalicular transporters in rat liver. J Biol Chem 1998 1.00
17 Phosphoinositide 3-kinase lipid products regulate ATP-dependent transport by sister of P-glycoprotein and multidrug resistance associated protein 2 in bile canalicular membrane vesicles. Proc Natl Acad Sci U S A 1999 0.97
18 Association of phosphatidylinositol 3-kinase with SHC in chronic myelogeneous leukemia cells. Oncogene 1995 0.96
19 PI 3-kinase activation in BCR/abl-transformed hematopoietic cells does not require interaction of p85 SH2 domains with p210 BCR/abl. Blood 1996 0.93
20 Tyrosine phosphorylation of the CD3-epsilon subunit of the T cell antigen receptor mediates enhanced association with phosphatidylinositol 3-kinase in Jurkat T cells. J Biol Chem 1997 0.90
21 Biosynthesis of porphyrin precursors. Purification and characterization of mammalian L-alanine:gamma,delta-dioxovaleric acid aminotransferase. J Biol Chem 1980 0.90
22 Probing fibroblast growth factor dimerization and role of heparin-like glycosaminoglycans in modulating dimerization and signaling. J Biol Chem 2001 0.89
23 Serine-rich region of the IL-2 receptor beta-chain is required for activation of phosphatidylinositol 3-kinase. Cell Immunol 1994 0.89
24 Tyrosine phosphorylation of p120cbl in BCR/abl transformed hematopoietic cells mediates enhanced association with phosphatidylinositol 3-kinase. Oncogene 1997 0.86
25 Paradoxical stimulation of both lipocortin and prostaglandin production in human amnion cells by dexamethasone. Biochem Biophys Res Commun 1988 0.86
26 Biosynthesis of porphyrin precursors: kinetic studies on mammalian L-alanine: gamma,delta-dioxovaleric acid aminotransferase. Int J Biochem 1980 0.83
27 Evidence for phosphatidylinositol 3-kinase-dependent T cell antigen receptor (TCR) signal transduction. Mol Immunol 1997 0.82
28 Phorbol ester treatment inhibits phosphatidylinositol 3-kinase activation by, and association with, CD28, a T-lymphocyte surface receptor. Proc Natl Acad Sci U S A 1995 0.81
29 Dynamin inhibits phosphatidylinositol 3-kinase in hematopoietic cells. Biochim Biophys Acta 2001 0.79
30 Phosphatidylinositol 3-kinase activity in murine erythroleukemia cells during DMSO-induced differentiation. Exp Cell Res 1995 0.77
31 Inactivation of wild-type BCR/ABL tyrosine kinase in hematopoietic cells by mild hyperthermia. Leukemia 2000 0.76
32 Naturally occurring ether-linked phosphatidylcholine activates phosphatidylinositol 3-kinase and stimulates cell growth. J Cell Biochem 1994 0.76
33 Expression of tie1 and tie2 proteins during reendothelialization in balloon-injured rat carotid artery. J Vasc Res 1999 0.76
34 Mitogenic signaling by cyclic adenosine monophosphate in chromaffin cells involves phosphatidylinositol 3-kinase activation. J Cell Biochem Suppl 2001 0.75
35 Signal transduction and phosphoinositide metabolism in liver. Prog Liver Dis 1990 0.75
36 Effect of a xanthine analog on human hepatocellular carcinoma cells (Alexander) in culture and in xenografts in SCID mice. Hepatology 1997 0.75
37 Anti-platelet and anti-DNA IgM in Waldenström macroglobulinemia and ITP. Am J Hematol 1987 0.75