Principles of solid-organ preservation by cold storage.

PubWeight™: 3.79‹?› | Rank: Top 1%

🔗 View Article (PMID 3282347)

Published in Transplantation on April 01, 1988

Authors

F O Belzer1, J H Southard

Author Affiliations

1: Department of Surgery, University of Wisconsin-Madison 53792.

Associated clinical trials:

University of Wisconsin Solution Versus New Parathyroid Transport Solution for Parathyroid Allotransplantation | NCT03051308

Clinical Trial of New Hypothermic Oxygenated Perfusion System Versus Static Cold Storage | NCT03837197

Articles citing this

(truncated to the top 100)

Pancreatic islet transplantation after upper abdominal exenteration and liver replacement. Lancet (1990) 4.18

Extended preservation of human liver grafts with UW solution. JAMA (1989) 3.99

Supercooling enables long-term transplantation survival following 4 days of liver preservation. Nat Med (2014) 2.31

Minocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition. Hepatology (2008) 2.22

Delayed graft function in the kidney transplant. Am J Transplant (2011) 2.06

Ezrin functionality and hypothermic preservation injury in LLC-PK1 cells. Cryobiology (2012) 1.73

Native and recombinant human hepatocyte growth factors are highly potent promoters of DNA synthesis in both human and rat hepatocytes. J Clin Invest (1991) 1.70

High molecular weight polyethylene glycol (PEG 15-20) maintains mucosal microbial barrier function during intestinal graft preservation. J Surg Res (2013) 1.51

State of the art in therapeutic hypothermia. Annu Rev Med (2011) 1.45

Molecular mediators of liver ischemia and reperfusion injury: a brief review. Mol Med (2008) 1.43

Evaluation of protocol before transplantation and after reperfusion biopsies from human orthotopic liver allografts: considerations of preservation and early immunological injury. Hepatology (1990) 1.38

Review of factors affecting the growth and survival of follicular grafts. J Cutan Aesthet Surg (2010) 1.33

Hepatic Retransplantation--an analysis of risk factors associated with outcome. Transplantation (1996) 1.22

Comparison of UW with other solutions for liver preservation in dogs. Clin Transplant (1989) 1.20

A 10-year experience with 290 pancreas transplants at a single institution. Ann Surg (1989) 1.19

In situ hypothermic perfusion of the liver versus standard total vascular exclusion for complex liver resection. Ann Surg (2005) 1.17

Human intrahepatic biliary epithelial cells proliferate in vitro in response to human hepatocyte growth factor. J Clin Invest (1992) 1.12

Cardiac preservation is enhanced in a heterotopic rat transplant model by supplementing the nitric oxide pathway. J Clin Invest (1994) 1.10

The UW solution for canine kidney preservation. Its specific effect on renal hemodynamics and microvasculature. Transplantation (1989) 1.04

Preservation methods for kidney and liver. Organogenesis (2009) 1.03

Protective effects of ezrin on cold storage preservation injury in the pig kidney proximal tubular epithelial cell line (LLC-PK1). Transplantation (2009) 1.02

Organ donation. II-Logistical disincentives to organ donation. BMJ (1990) 1.00

Mitochondrial dysfunction and biogenesis: do ICU patients die from mitochondrial failure? Ann Intensive Care (2011) 0.98

Mild hypothermia attenuates mitochondrial oxidative stress by protecting respiratory enzymes and upregulating MnSOD in a pig model of cardiac arrest. PLoS One (2012) 0.98

Prevention of renal injury after induction of ozone tolerance in rats submitted to warm ischaemia. Mediators Inflamm (1999) 0.98

Effects of cyclopiazonic acid and ryanodine on cytosolic calcium and contraction in vascular smooth muscle. Br J Pharmacol (1996) 0.98

Personal experience with the procurement of 132 liver allografts. Transpl Int (1989) 0.98

Hypoxia inducible factor-1alpha accumulation in steatotic liver preservation: role of nitric oxide. World J Gastroenterol (2010) 0.97

Effect of intraportal glucose infusion on hepatic glycogen content and degradation, and outcome of liver transplantation. Ann Surg (1992) 0.96

Effects of 10 minutes of ischemic preconditioning of the cadaveric liver on the graft's preservation and function: the ying and the yang. Ann Surg (2005) 0.95

Restoration of the cAMP second messenger pathway enhances cardiac preservation for transplantation in a heterotopic rat model. J Clin Invest (1993) 0.94

Status of systemic oxidative stress during therapeutic hypothermia in patients with post-cardiac arrest syndrome. Oxid Med Cell Longev (2013) 0.94

Lazaroid U-74389G for 48-hour canine liver preservation. Transplantation (1996) 0.93

IGL-1 solution reduces endoplasmic reticulum stress and apoptosis in rat liver transplantation. Cell Death Dis (2012) 0.93

Characterization of the human liver vasopressin receptor. Profound differences between human and rat vasopressin-receptor-mediated responses suggest only a minor role for vasopressin in regulating human hepatic function. Biochem J (1991) 0.93

History of clinical transplantation. World J Surg (2000) 0.91

Calcium compartments in vascular smooth muscle cells as detected by aequorin signal. Br J Pharmacol (1995) 0.90

Principles of low temperature cell preservation. Heart Fail Rev (2003) 0.89

Hypothermic temperature effects on organ survival and restoration. Sci Rep (2015) 0.87

Endothelial targeting with C1-inhibitor reduces complement activation in vitro and during ex vivo reperfusion of pig liver. Clin Exp Immunol (2001) 0.85

Hypothermic stress leads to activation of Ras-Erk signaling. J Clin Invest (1999) 0.85

A collection of primary tissue cultures of tumors from vacuum packed and cooled surgical specimens: a feasibility study. PLoS One (2013) 0.84

Effects of methylprednisolone and its liver-targeted dextran prodrug on ischemia-reperfusion injury in a rat liver transplantation model. Pharm Res (2007) 0.84

Pancreatic autotransplantation in chronic pancreatitis. World J Surg (2003) 0.83

Adding ROS quenchers to cold K+ cardioplegia reduces superoxide emission during 2-hour global cold cardiac ischemia. J Cardiovasc Pharmacol Ther (2011) 0.83

Polyethylene glycol rinse solution: an effective way to prevent ischemia-reperfusion injury. World J Gastroenterol (2014) 0.83

Effects of Institut Georges Lopez-1 and Celsior preservation solutions on liver graft injury. World J Gastroenterol (2015) 0.83

Pancreas preservation for pancreas and islet transplantation. Curr Opin Organ Transplant (2008) 0.83

A new liver perfusion and preservation system for transplantation research in large animals. J Invest Surg (1990) 0.83

Altered cellular membrane fluidity levels and lipid peroxidation during experimental pancreas transplantation. J Bioenerg Biomembr (2012) 0.83

Preservation solutions for cardiac and pulmonary donor grafts: a review of the current literature. J Thorac Dis (2014) 0.82

Prednisolone has a positive effect on the kidney but not on the liver of brain dead rats: a potencial role in complement activation. J Transl Med (2014) 0.81

Current status of renal transplantation. West J Med (1990) 0.81

Hepatic artery thrombosis following pediatric liver transplantation: Assessment of blood flow measurement in allografts. Clin Transplant (1989) 0.81

Significance of lecithin:cholesterol acyltransferase activity as a prognostic indicator of early allograft function in clinical liver transplantation. Transplantation (1989) 0.81

Hypothermic in situ perfusion of the porcine liver using Celsior or Ringer-lactate solution. Langenbecks Arch Surg (2008) 0.81

Importance and limits of ischemia in renal partial surgery: experimental and clinical research. Adv Urol (2008) 0.80

Redefining the properties of an osmotic agent in an intestinal-specific preservation solution. World J Gastroenterol (2010) 0.80

MitoQ blunts mitochondrial and renal damage during cold preservation of porcine kidneys. PLoS One (2012) 0.80

Cold storage of rat hepatocyte suspensions for one week in a customized cold storage solution--preservation of cell attachment and metabolism. PLoS One (2012) 0.79

Analysis of machine perfusion benefits in kidney grafts: a preclinical study. J Transl Med (2011) 0.79

Preoperative assessment of risk in liver transplantation: a multivariate analysis in 2376 cases of the UW era. Transplant Proc (1997) 0.79

An innovative hyperbaric hypothermic machine perfusion protects the liver from experimental preservation injury. ScientificWorldJournal (2012) 0.79

Prolonged rat cardiac preservation with UW lactobionate solution. Transplant Proc (1989) 0.79

Proteomic analysis of tyrosine phosphorylation during human liver transplantation. Proteome Sci (2007) 0.79

Improving Donor Livers by Inhibiting TNF-α Production. Ochsner J (2010) 0.79

Effects of ischemic preconditioning in a pig model of large-for-size liver transplantation. Clinics (Sao Paulo) (2015) 0.79

Time dependent changes in aortic tissue during cold storage in physiological solution. Biochim Biophys Acta (2011) 0.79

Organomatics and organometrics: Novel platforms for long-term whole-organ culture. Technology (Singap World Sci) (2014) 0.79

Supercooling preservation and transplantation of the rat liver. Nat Protoc (2015) 0.78

Current status of intestinal transplantation. Adv Surg (1994) 0.78

Effect of storage temperature on cultured epidermal cell sheets stored in xenobiotic-free medium. PLoS One (2014) 0.78

Rapid decrease in cellular sodium and chloride content during cold incubation of cultured liver endothelial cells and hepatocytes. Biochem J (1997) 0.78

Adenosine 5'triphosphate transport and accumulation during the cold preservation of rat hepatocytes in University of Wisconsin solution. World J Gastroenterol (2005) 0.77

Protection of mitochondria during cold storage of liver and following transplantation: comparison of the two solutions, University of Wisconsin and Eurocollins. J Bioenerg Biomembr (2006) 0.77

Celsior versus University of Wisconsin preserving solutions for liver transplantation: postreperfusion syndrome and outcome of a 5-year prospective randomized controlled study. World J Surg (2011) 0.77

Protective effect of doxorubicin induced heat shock protein 72 on cold preservation injury of rat livers. World J Gastroenterol (2004) 0.77

Development of pancreas storage solutions: Initial screening of cytoprotective supplements for β-cell survival and metabolic status after hypothermic storage. Biopreserv Biobank (2013) 0.77

Impact of cold ischemia on mitochondrial function in porcine hearts and blood vessels. Int J Mol Sci (2013) 0.76

Strategies to rescue steatotic livers before transplantation in clinical and experimental studies. World J Gastroenterol (2013) 0.76

A luminance-based heart chip assay for assessing the efficacy of graft preservation solutions in heart transplantation in rats. Heart Asia (2013) 0.76

Evaluating the effects of extended cold ischemia on interstitial metabolite in grafts in kidney transplantation using microdialysis. Langenbecks Arch Surg (2012) 0.75

Performance of cold-preserved rat liver Microorgans as the biological component of a simplified prototype model of bioartificial liver. World J Hepatol (2016) 0.75

Donor gluconate rescues livers from uncontrolled donation after cardiac death. Surgery (2015) 0.75

Cardioplegia at subnormothermia facilitates rapid functional resuscitation of hearts preserved in SOMAH for transplants. J Cardiothorac Surg (2014) 0.75

Protective effects of the lazaroid U74500A and lidoflazine on liver preservation with UW solution. Transpl Int (1993) 0.75

Improved method of porcine renal allografting for transplantation research. J Invest Surg (1991) 0.75

The transplantation of gastrointestinal organs. Gastroenterology (1993) 0.75

Survey of Apoptosis After Hypothermic Storage of a Pancreatic β-Cell Line. Biopreserv Biobank (2016) 0.75

Bioelectrical impedance may predict cell viability during ischemia and reperfusion in rat liver. J Korean Med Sci (2010) 0.75

Kidney transplant revisited (1990) West J Med (1990) 0.75

Fluorometric study of the viability of rat liver grafts after simple cold storage with UW solution versus Euro-Collins solution. Transplant Proc (1991) 0.75

Protective mechanisms of hypothermia in liver surgery and transplantation. Mol Med (2015) 0.75

Innovative cold storage of donor organs using the Paragonix Sherpa Pak ™ devices. Heart Lung Vessel (2015) 0.75

Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines. Am J Transplant (2016) 0.75

Sodium lactobionate sucrose solution for canine liver and kidney preservation. Transplant Proc (1993) 0.75

Subzero 12-hour Nonfreezing Cryopreservation of Porcine Heart in a Variable Magnetic Field. Transplant Direct (2015) 0.75

Acute renal injury after partial hepatectomy. World J Hepatol (2016) 0.75

Phosphorus 31-nuclear magnetic resonance spectroscopy of rat liver during simple storage or continuous hypothermic perfusion. J Lab Clin Med (1992) 0.75

Comparative analysis of in situ versus ex situ perfusion on flow and microcirculation in kidney procurement: research on a porcine model. Transplant Res (2013) 0.75

Articles by these authors

(truncated to the top 100)

Relationship between configuration, function, and permeability in calcium-treated mitochondria. J Biol Chem (1976) 2.15

72-hour preservation of the canine pancreas. Transplantation (1987) 1.55

Preservation of the canine liver for 24-48 hours using simple cold storage with UW solution. Transplantation (1988) 1.33

Successful 72-hour cold storage kidney preservation with UW solution. Transplant Proc (1988) 1.14

Paired moving charge model of energy coupling. III. Intrinsic ionophores in energy coupling systems. Proc Natl Acad Sci U S A (1975) 1.09

Organ preservation. Surg Clin North Am (1994) 1.05

The isolated perfused rabbit liver as a model for assessment of organ preservation. Transplant Proc (1988) 1.04

Combined cold storage-perfusion preservation with a new synthetic perfusate. Transplantation (1989) 0.99

A comparison of cold storage solutions for hepatic preservation using the isolated perfused rabbit liver. Cryobiology (1988) 0.96

Successful 72-hour cold storage of dog kidneys with UW solution. Transplantation (1988) 0.94

Development of a cold storage solution for pancreas preservation. Cryobiology (1986) 0.94

Synthetic perfusate for kidney preservation. Its use in 72-hour preservation of dog kidneys. Arch Surg (1983) 0.93

Speed of respiration-dependent proton ejection by mitochondria. Application of a pH-measuring system with 10-msec resolution. Arch Biochem Biophys (1971) 0.92

An analysis of the components in UW solution using the isolated perfused rabbit liver. Transplantation (1988) 0.91

Control of the energy coupling modes in mitochondria by mercurials. Biochem Biophys Res Commun (1974) 0.91

Effect of polyethylene glycol on lipid peroxidation in cold-stored rat hepatocytes. Cryobiology (1991) 0.91

Organ preservation and transplantation. Prog Clin Biol Res (1986) 0.90

Successful five-day perfusion preservation of the canine kidney. Transplantation (1989) 0.90

Preservation of dog liver, kidney, and pancreas using the Belzer-UW solution with a high-sodium and low-potassium content. Transplantation (1989) 0.90

Control of canine kidney cortex slice volume and ion distribution at hypothermia by impermeable anions. Cryobiology (1980) 0.90

Seventy-two-hour preservation of the canine liver by machine perfusion. Transplantation (1990) 0.88

Inhibition of ischemic induced cellular swelling in kidney cortex tissue by lactobionate anions. J Trauma (1982) 0.86

Kidney preservation. Surg Clin North Am (1978) 0.86

Changes in gut function during hibernation: implications for bowel transplantation and surgery. Gut (2001) 0.86

Mechanisms of ATP depletion in the cold-stored heart. Transplant Proc (1991) 0.86

Cold storage sensitizes hepatocytes to oxidative stress injury. Transpl Int (1997) 0.85

Glycine protects hepatocytes from injury caused by anoxia, cold ischemia and mitochondrial inhibitors, but not injury caused by calcium ionophores or oxidative stress. Hepatology (1993) 0.85

Livers from fasted rats acquire resistance to warm and cold ischemia injury. Transplantation (1993) 0.84

Energy coupling in lysolecithin-treated submitochondrial particles. Biochem Biophys Res Commun (1976) 0.84

Adsorption of lactate dehydrogenase to the particulate fraction of homogenized skeletal muscle. Nature (1966) 0.84

Oxygen-derived free radical damage in organ preservation: activity of superoxide dismutase and xanthine oxidase. Surgery (1987) 0.84

Membrane stabilizing effects of calcium and taxol during the cold storage of isolated rat hepatocytes. Transplantation (1999) 0.84

Limitations of heart preservation by cold storage. Transplantation (1992) 0.83

Induction of transmembrane proton transfer by mercurials in mitochondria. II. Release of a Na+-K+ ionophore. J Biol Chem (1974) 0.82

Stimulation of ATP synthesis in hypothermically perfused dog kidneys by adenosine and PO4. Cryobiology (1984) 0.82

Improved preservation of rat hindlimbs with the University of Wisconsin solution and butanedione monoxime. Plast Reconstr Surg (1997) 0.82

Improved myocardial ischemic tolerance by contractile inhibition with 2,3-butanedione monoxime. Ann Thorac Surg (1992) 0.82

The future of kidney preservation. Transplantation (1980) 0.82

Alteration in cellular calcium and mitochondrial functions in the rat liver during cold preservation. Transplantation (1998) 0.82

High affinity binding of Ca++ in mitochondria: a reappraisal. Biochem Biophys Res Commun (1974) 0.81

Comparison of the effect of temperature on kidney cortex mitochondria from rabbit, dog, pig, and human: Arrhenius plots of ADP-stimulated respiration. Cryobiology (1983) 0.81

Current status of organ preservation with University of Wisconsin solution. Arch Pathol Lab Med (1991) 0.80

Effect of cold storage on tissue and cellular glutathione. Cryobiology (1991) 0.80

Effects of short-term hypothermic perfusion and cold storage on function of the isolated-perfused dog kidney. Cryobiology (1985) 0.80

Effect of glycine in dog and rat liver transplantation. Transplantation (1993) 0.80

Organ preservation: experience with University of Wisconsin solution and plans for the future. Clin Transplant (1990) 0.80

Donor brain death reduces survival after transplantation in rat livers preserved for 20 hr. Transplantation (2001) 0.80

Use of UW cold storage solution for machine perfusion of kidneys. Transplant Proc (1990) 0.79

Effects of hypothermic kidney preservation on the isolated perfused kidney: a comparison of reperfusion methods. Cryobiology (1985) 0.79

Effect of hypothermia on intracellular Ca2+ in rabbit renal tubules suspended in UW-gluconate preservation solution. Cryobiology (1996) 0.79

Glycine prevention of cold ischemic injury in isolated hepatocytes. Cryobiology (1991) 0.78

Hypothermic preservation of hepatocytes. I. Role of cell swelling. Cryobiology (1989) 0.78

Forty-hour preservation of the rabbit heart: optimal osmolarity, [Mg2+], and pH of a modified UW solution. Ann Thorac Surg (1994) 0.78

Comparison of the effects of adenine-ribose with adenosine for maintenance of ATP concentrations in 5-day hypothermically perfused dog kidneys. Cryobiology (1988) 0.78

Comparison of solutions for preservation of the rabbit liver as tested by isolated perfusion. Transpl Int (1995) 0.78

Evaluation of intestinal villus height in rats after ischemia and reperfusion by administration of superoxide dismutase, polyethylene glycol-conjugated superoxide dismutase, and two 21-aminosteroids. Am J Vet Res (1992) 0.78

Effects of method of preservation on functions of livers from fed and fasted rabbits. Cryobiology (1991) 0.78

TNF-alpha and heat-shock protein gene expression in ischemic-injured liver from fasted and non-fasted rats. Role of donor fasting in the prevention of reperfusion injury following liver transplantation. Transpl Int (1998) 0.78

Hypothermic preservation of hepatocytes. III. Effects of resuspension media on viability after up to 7 days of storage. Hepatology (1991) 0.78

Hypothermic perfusion of rabbit livers: effect of perfusate composition (Ca and lactobionate) on enzyme release and tissue swelling. Cryobiology (1989) 0.78

Effects of mannitol and chlorpromazine pretreatment of rabbits on kidney mitochondria following in vivo ischemia and reflow. Life Sci (1981) 0.78

Effect of drug treatment on liver-slice function following 72-hour hypothermic perfusion. Cryobiology (1986) 0.78

Induction of transmembrane proton transfer by mercurials in mitochondria. I. Ion movements accompanying transmembrane proton transfer. J Biol Chem (1973) 0.78

A comparison of histidine-lactobionate and UW solution in 48-hour dog liver preservation. Transplantation (1992) 0.78

Importance of glutathione and adenosine in cold storage of the kidney. Transplant Proc (1990) 0.77

Inhibition of warm ischemic injury to rat liver, pancreas, and heart grafts by controlling the nutritional status of both donor and recipient. Surg Today (1997) 0.77

Donor nutritional status--a determinant of liver preservation injury. Transplantation (1996) 0.77

Effect of oxidized and reduced glutathione in liver preservation. Transplantation (1990) 0.77

The effects of fasting on the quality of liver preservation by simple cold storage. Transplantation (1990) 0.77

Prolonged kidney preservation by inhibition of arachidonic acid metabolism. Transplant Proc (1993) 0.77

Effect of glutathione and glycine in kidney preservation. Transplant Proc (1993) 0.77

Examination of TNF-alpha and heat shock protein gene expression in ischemic injured livers from fasted and nonfasted rats. Transplant Proc (1998) 0.77

Hypothermic preservation of hepatocytes. II. Importance of Ca2 and amino acids. Cryobiology (1990) 0.77

Effects of chlorpromazine and methylprednisolone on perfusion preservation of rabbit livers. Cryobiology (1988) 0.77

Improved maintenance of adenosine triphosphate in five-day perfused kidneys with adenine and ribose. Transplant Proc (1987) 0.77

Efficacy of 48-hour pancreas preservation with UW solution in the dog allograft model. Transplant Proc (1988) 0.77

Adenine stimulation of adenosine triphosphate synthesis in cold-stored hepatocytes. Transplantation (1991) 0.77

The use of myocytes as a model for developing successful heart preservation solutions. Transplantation (1991) 0.77

Combined cold storage and perfusion preservation of the canine liver. Transplant Proc (1990) 0.77

Effect of liver preservation on hepatocyte calcium and ATP regeneration. Transplant Proc (1997) 0.77

The effect of energy charge on the activity of solubilized and bound mitochondrial hexokinase from chicken skeletal muscle. Arch Biochem Biophys (1972) 0.77

Loss of oxidative phosphorylation in mitochondria isolated from kidneys of mercury poisoned rats. Biochem Biophys Res Commun (1973) 0.77

Denaturation of albumin: a critical factor in long-term kidney preservation. J Surg Res (1981) 0.77

Effects of hypothermia on canine kidney mitochondria. Cryobiology (1980) 0.76

The effect of pH on the viability of hypothermically stored rat hepatocytes. Cryobiology (1989) 0.76

Urea and protein synthesis in cold-preserved isolated rat hepatocytes. Hepatology (1992) 0.76

Hypothermic machine perfusion of rat livers preserves endothelial cell function. Transplant Proc (2005) 0.76

Preservation of renal function by adenosine-stimulated ATP synthesis in hypothermically perfused dog kidneys. Cryobiology (1985) 0.76

The 24- to 48-hour preservation of canine liver by simple cold storage using UW lactobionate solution. Transplant Proc (1989) 0.76

Membrane stabilizing effects of glycine during kidney cold storage and reperfusion. Transplant Proc (1991) 0.76

Kupffer cells depress hepatocyte protein synthesis on cold storage of the rat liver. Transplantation (1994) 0.76

The importance of a colloid in canine pancreas preservation. Transplantation (1992) 0.76

Successful 7-day perfusion preservation of the canine kidney. Transplant Proc (1993) 0.76

Effects of hypothermic perfusion of kidneys on tissue and mitochondrial phospholipids. Cryobiology (1984) 0.76

Beneficial effects of adenosine and phosphate in kidney preservation. Transplantation (1983) 0.76

Toxicity of oxygen to mitochondrial respiratory activity in hypothermically perfused canine kidneys. Transplantation (1980) 0.76

Comparison of PBS, HTK, and UW solutions for kidney preservation. Transplant Proc (1991) 0.76

A new perfusate for kidney preservation. Transplantation (1982) 0.76

Regeneration of ATP in kidney slices after warm ischemia and hypothermic preservation. Transpl Int (1995) 0.76

Glutathione depletion in cold-stored organs. Transplant Proc (1990) 0.76