Power of the affected-sib-pair method for heterogeneous disorders.

PubWeight™: 2.16‹?› | Rank: Top 2%

🔗 View Article (PMID 3282981)

Published in Genet Epidemiol on January 01, 1988

Authors

L R Goldin1, E S Gershon

Author Affiliations

1: Clinical Neurogenetics Branch, National Institute of Mental Health, Bethesda, Maryland 20892.

Articles by these authors

(truncated to the top 100)

Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia. Mol Psychiatry (2002) 4.51

A family study of schizoaffective, bipolar I, bipolar II, unipolar, and normal control probands. Arch Gen Psychiatry (1982) 2.75

Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene. Proc Natl Acad Sci U S A (1994) 2.54

Singleton deletions throughout the genome increase risk of bipolar disorder. Mol Psychiatry (2008) 2.50

Evidence of linkage disequilibrium between schizophrenia and the SCa1 CAG repeat on chromosome 6p23. Am J Hum Genet (1996) 2.19

A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2. Proc Natl Acad Sci U S A (1999) 1.96

Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants. Mol Psychiatry (2012) 1.84

Genetic mapping of the Gs-alpha subunit gene (GNAS1) to the distal long arm of chromosome 20 using a polymorphism detected by denaturing gradient gel electrophoresis. Genomics (1991) 1.84

Mutations of the Gs alpha-subunit gene in Albright hereditary osteodystrophy detected by denaturing gradient gel electrophoresis. Proc Natl Acad Sci U S A (1990) 1.82

Optimal ascertainment strategies to detect linkage to common disease alleles. Am J Hum Genet (1998) 1.77

X-chromosome markers and manic-depressive illness. Rejection of linkage to Xq28 in nine bipolar pedigrees. Arch Gen Psychiatry (1990) 1.72

Whole-genome association mapping of gene expression in the human prefrontal cortex. Mol Psychiatry (2010) 1.69

Regional meta-analysis of published data supports linkage of autism with markers on chromosome 7. Mol Psychiatry (2002) 1.67

Close linkage of c-Harvey-ras-1 and the insulin gene to affective disorder is ruled out in three North American pedigrees. Nature (1987) 1.61

Psychiatric disorders in the first-degree relatives of probands with bulimia nervosa. Am J Psychiatry (1989) 1.46

Suggestive evidence for a schizophrenia susceptibility locus on chromosome 6q and a confirmation in an independent series of pedigrees. Genomics (1997) 1.44

Diagnostic accuracy and confusability analyses: an application to the Diagnostic Interview for Genetic Studies. Psychol Med (1996) 1.38

Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 4, 7, 9, 18, 19, 20, and 21q. Am J Med Genet (1997) 1.36

Family-based association of FKBP5 in bipolar disorder. Mol Psychiatry (2008) 1.34

Initial genomic scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 3, 5, 15, 16, 17, and 22. Am J Med Genet (1997) 1.30

Birth-cohort changes in manic and depressive disorders in relatives of bipolar and schizoaffective patients. Arch Gen Psychiatry (1987) 1.29

Psychiatric disorders in the relatives of probands with affective disorders. The Yale University--National Institute of Mental Health Collaborative Study. Arch Gen Psychiatry (1984) 1.26

Tics and Tourette's disorder: a 2- to 7-year follow-up of 54 obsessive-compulsive children. Am J Psychiatry (1992) 1.15

Initial genome screen for bipolar disorder in the NIMH genetics initiative pedigrees: chromosomes 2, 11, 13, 14, and X. Am J Med Genet (1997) 1.15

Two gene co-expression modules differentiate psychotics and controls. Mol Psychiatry (2012) 1.15

Follow-up study on a susceptibility locus for schizophrenia on chromosome 6q. Am J Med Genet (1999) 1.14

Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 1, 6, 8, 10, and 12. Am J Med Genet (1997) 1.10

The detection of major loci by segregation and linkage analysis: a simulation study. Genet Epidemiol (1984) 1.09

Segregation and linkage studies of plasma dopamine-beta-hydroxylase (DBH), erythrocyte catechol-O-methyltransferase (COMT), and platelet monoamine oxidase (MAO): possible linkage between the ABO locus and a gene controlling DBH activity. Am J Hum Genet (1982) 1.08

Erythrocyte soluble catechol-O-methyl transferase activity in primary affective disorder. A clinical and genetic study. Arch Gen Psychiatry (1975) 1.07

Affected-sib-pair analyses reveal support of prior evidence for a susceptibility locus for bipolar disorder, on 21q. Am J Hum Genet (1996) 1.03

The inheritance of affective disorders: a review of data and of hypotheses. Behav Genet (1976) 1.03

Faster cholinergic REM sleep induction in euthymic patients with primary affective illness. Science (1980) 1.03

Clinical methods in psychiatric genetics. I. Robustness of genetic marker investigative strategies. Acta Psychiatr Scand (1986) 1.02

Heritable factors in the severity of affective illness. Biol Psychiatry (1976) 1.00

A family study of the association of increased ventricular size with schizophrenia. Arch Gen Psychiatry (1986) 0.99

Women with bipolar disorder: findings from the NIMH Genetics Initiative sample. Psychopharmacol Bull (1998) 0.98

Use of exact and adjusted liability scores to detect genes affecting common traits. Genet Epidemiol (1995) 0.98

Information from relatives. Diagnosis of affective disorders. Arch Gen Psychiatry (1984) 0.98

Linkage analysis of fifty-seven microsatellite loci to bipolar disorder. Neuropsychopharmacology (1993) 0.98

Genetic and physical mapping of the human cannabinoid receptor gene to chromosome 6q14-q15. New Biol (1991) 0.94

Psychosis with ordinary doses of propranolol. Ann Intern Med (1979) 0.94

Behavioral, biochemical and neuroendocrine responses to amphetamine in normal twins and 'well-state' bipolar patients. Psychoneuroendocrinology (1982) 0.94

Genome-wide linkage analysis of 972 bipolar pedigrees using single-nucleotide polymorphisms. Mol Psychiatry (2011) 0.93

Clinical features of illness in siblings with schizophrenia or schizoaffective disorder. Arch Gen Psychiatry (1987) 0.93

Segregation and linkage analyses in families of patients with bipolar, unipolar, and schizoaffective mood disorders. Am J Hum Genet (1983) 0.93

Fine mapping supports previous linkage evidence for a bipolar disorder susceptibility locus on 13q32. Am J Med Genet (2001) 0.93

Color blindness not closely linked to bipolar illness. Report of a new pedigree series. Arch Gen Psychiatry (1979) 0.93

Genetic tests of biologic systems in affective disorders. Mol Psychiatry (2005) 0.92

The Family Attitudes Questionnaire. Patients' and spouses' views of bipolar illness. Arch Gen Psychiatry (1981) 0.91

Perinatal complications and reduced size of brain limbic structures in familial schizophrenia. Schizophr Bull (1988) 0.90

Effects of injected sympathomimetic amines on plasma catecholamines and circulatory variables in man. Life Sci (1983) 0.89

Description of the Genetic Analysis Workshop 10 bipolar disorder linkage data sets. Genet Epidemiol (1997) 0.89

Patient and family attitudes about schizophrenia: implications for genetic counseling. Schizophr Bull (1982) 0.89

Hostility and depression. Psychiatry (1968) 0.89

X-linkage: ascertainment through doubly ill probands. J Psychiatr Res (1977) 0.89

Sociocultural and demographic correlates of affective disorders in Jerusalem. J Psychiatr Res (1975) 0.88

Exclusion of linkage to 5q11-13 in families with schizophrenia and other psychiatric disorders. Nature (1989) 0.88

Serotonin transporter (5-HTT) gene and bipolar affective disorder. Am J Med Genet (1998) 0.88

Reduction in temporal lobe size in siblings with schizophrenia: a magnetic resonance imaging study. Psychiatry Res (1990) 0.88

Sampling strategies for linkage studies. Eur Arch Psychiatry Clin Neurosci (1991) 0.88

Cholinergic regulation of mood and REM sleep: potential model and marker of vulnerability to affective disorder. Am J Psychiatry (1982) 0.88

The historical context of Franz Kallmann and psychiatric genetics. Arch Psychiatr Nervenkr (1970) (1981) 0.87

Herpes simplex virus, cytomegalovirus and Epstein-Barr virus antibody titres in sera from schizophrenic patients. Psychol Med (1986) 0.87

Imipramine effects upon hostility in depression. J Nerv Ment Dis (1970) 0.87

The role of plasma amine oxidase, platelet monoamine oxidase, and red cell catechol-O-methyl transferase in severe behavioral reactions to disulfiram. Am J Psychiatry (1979) 0.86

Behavioral, physiological, and neuroendocrine responses to arecoline in normal twins and "well state" bipolar patients. Psychiatry Res (1983) 0.85

Genome-wide association in bipolar. Mol Psychiatry (2008) 0.85

Multiple threshold models for the affective disorders: the Yale-NIMH collaborative family study. J Psychiatr Res (1985) 0.85

Muscarinic cholinergic receptors on skin fibroblasts in familial affective disorder. N Engl J Med (1984) 0.85

Genetic linkage mapping of the m4 human muscarinic receptor (CHRM4). Genomics (1992) 0.84

A linkage study of bipolar illness. Arch Gen Psychiatry (1997) 0.84

Lithium in children of lithium-responding parents. Psychiatry Res (1981) 0.84

Suggestive evidence of a locus on chromosome 10p using the NIMH genetics initiative bipolar affective disorder pedigrees. Am J Med Genet (2000) 0.84

Genetic strategies in biological psychiatry. Arch Gen Psychiatry (1978) 0.84

Search for a schizophrenia susceptibility locus on human chromosome 22. Am J Med Genet (1994) 0.84

Blindness and reliability in lifetime psychiatric diagnosis. Arch Gen Psychiatry (1979) 0.83

Lithium carbonate response in depression. Prediction by unipolar/bipolar illness, average-evoked response, catechol-O-methyl transferase, and family history. Arch Gen Psychiatry (1975) 0.83

An integrated physical map of 18p11.2: a susceptibility region for bipolar disorder. Mol Psychiatry (1998) 0.83

Platelet vasopressin receptors in bipolar affective illness. Psychiatry Res (1982) 0.83

Validation of criteria for major depression through controlled family study. J Affect Disord (1987) 0.83

Cytogenetic studies of males with schizophrenia. Screening for the fragile X chromosome and other chromosomal abnormalities. Schizophr Res (1991) 0.82

A collaborative study of genetic linkage of bipolar manic-depressive illness and red/green colorblindness. A project of the biological psychiatry collaborative program of the world health organization. Acta Psychiatr Scand (1980) 0.82

Unipolar relatives in bipolar pedigrees: a search for elusive indicators of underlying bipolarity. Am J Med Genet (1996) 0.82

Catecholamine metabolism in affective disorders. IV. Preliminary studies of norepinephrine metabolism in depressed patients treated with amitriptyline. J Psychiatr Res (1972) 0.82

Genetic mapping of adrenergic receptor genes in humans. J Mol Med (Berl) (1995) 0.82

Family and genetic studies of affective disorders. Arch Gen Psychiatry (1988) 0.82

The effects of field inversion electrophoresis on small DNA fragment mobility and its relevance to DNA polymorphism research. Appl Theor Electrophor (1988) 0.81

Monoamine oxidase type A in fibroblasts from patients with bipolar depressive illness. Psychiatry Res (1980) 0.81

Mutation screening of two candidate genes from 13q32 in families affected with Bipolar disorder: human peptide transporter (SLC15A1) and human glypican5 (GPC5). BMC Genomics (2002) 0.81

The question of X-linkage in bipolar manic-depressive illness. J Psychiatr Res (1977) 0.81

Reduced plasma and CSF gamma-aminobutyric acid in affective illness: effect of lithium carbonate. Biol Psychiatry (1983) 0.81

No association of trace amine receptor genes with bipolar disorder. Mol Psychiatry (2007) 0.81

CSF substance P immunoreactivity in affective disorders. Biol Psychiatry (1985) 0.80

Intravenous GABA administration is anxiogenic in man. Psychiatry Res (1986) 0.80

Autosomal models of sex effect in bipolar-related major affective illness. J Psychiatr Res (1977) 0.80

Platelet monoamine oxidase (MAO) activity: evidence for a single major locus. Am J Hum Genet (1984) 0.80

Relationship of HLA to schizophrenia in 10 nuclear families. Psychiatry Res (1987) 0.80

Epstein-Barr virus and depression. Arch Gen Psychiatry (1986) 0.80

Separate mechanisms for behavioral, cardiovascular, and hormonal responses to dextroamphetamine in man. Psychopharmacology (Berl) (1984) 0.79