Published in Annu Rev Immunol on January 01, 1988
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Type II hereditary angioneurotic edema that may result from a single nucleotide change in the codon for alanine-436 in the C1 inhibitor gene. Proc Natl Acad Sci U S A (1990) 0.87
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Plasma levels of C1- inhibitor complexes and cleaved C1- inhibitor in patients with hereditary angioneurotic edema. J Clin Invest (1990) 0.85
Endothelial targeting with C1-inhibitor reduces complement activation in vitro and during ex vivo reperfusion of pig liver. Clin Exp Immunol (2001) 0.85
Safety and efficacy of physician-supervised self-managed C1 inhibitor replacement therapy. Int Arch Allergy Immunol (2011) 0.84
Depression and anxiety in patients with hereditary angioedema. Ann Allergy Asthma Immunol (2013) 0.83
Crucial residues in the carboxy-terminal end of C1 inhibitor revealed by pathogenic mutants impaired in secretion or function. J Clin Invest (1995) 0.83
Modern complement analysis. Clin Diagn Lab Immunol (2003) 0.83
Transinhibition of C1 inhibitor synthesis in type I hereditary angioneurotic edema. J Clin Invest (1993) 0.83
Nonsense mutations affect C1 inhibitor messenger RNA levels in patients with type I hereditary angioneurotic edema. J Clin Invest (1991) 0.81
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Characterization of C1 inhibitor binding to neutrophils. Immunology (1991) 0.79
A novel human complement-related protein, C1r-like protease (C1r-LP), specifically cleaves pro-C1s. Biochem J (2005) 0.79
Rapid and sensitive techniques for identification and analysis of 'reactive-centre' mutants of C1-inhibitor proteins contained in type II hereditary angio-oedema plasmas. Biochem J (1990) 0.79
C1-Inhibitor Decreases the Release of Vasculitis-Like Chemotactic Endothelial Microvesicles. J Am Soc Nephrol (2017) 0.78
Ecallantide for the treatment of hereditary angiodema in adults. Clin Med Insights Cardiol (2011) 0.78
Degradation of C1-inhibitor by plasmin: implications for the control of inflammatory processes. Mol Med (1997) 0.78
Chymotrypsin inhibitory activity of normal C1-inhibitor and a P1 Arg to His mutant: evidence for the presence of overlapping reactive centers. Protein Sci (1993) 0.78
Cinryze as the first approved C1 inhibitor in the USA for the treatment of hereditary angioedema: approval, efficacy and safety. J Blood Med (2010) 0.78
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Mechanism of action of anti-C1-inhibitor autoantibodies: prevention of the formation of stable C1s-C1-inh complexes. Mol Med (1998) 0.76
Recombinant C1 inhibitor P5/P3 variants display resistance to catalytic inactivation by stimulated neutrophils. J Clin Invest (1993) 0.76
alpha(1)-Proteinase inhibitor mutants with specificity for plasma kallikrein and C1s but not C1. Protein Sci (2002) 0.75
Laparoscopic splenectomy in a patient with acquired angioneurotic edema. JSLS (2000) 0.75
Consumption of C4b-binding protein (C4BP) during in vivo activation of the classical complement pathway. Clin Exp Immunol (1999) 0.75
Diagnosis and screening of patients with hereditary angioedema in primary care. Ther Clin Risk Manag (2016) 0.75
The pathophysiology of hereditary angioedema. World Allergy Organ J (2010) 0.75
Screening for hereditary angioedema (HAE) at 13 emergency centers in Osaka, Japan: A prospective observational study. Medicine (Baltimore) (2017) 0.75
A mutation unique in serine protease inhibitors (serpins) identified in a family with type II hereditary angioneurotic edema. Mol Med (1995) 0.75
Hereditary Angioedema as a Metabolic Liver Disorder: Novel Therapeutic Options and Prospects for Cure. Front Immunol (2016) 0.75
Trypanosoma cruzi Evades the Complement System as an Efficient Strategy to Survive in the Mammalian Host: The Specific Roles of Host/Parasite Molecules and Trypanosoma cruzi Calreticulin. Front Microbiol (2017) 0.75