Published in J Leukoc Biol on July 01, 1988
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An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro. J Exp Med (1989) 2.27
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Kinetic characteristics of nitric oxide synthase from rat brain. Biochem J (1990) 2.00
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Biosynthesis of nitric oxide activates iron regulatory factor in macrophages. EMBO J (1993) 1.83
Multiple cytokines are required to induce hepatocyte nitric oxide production and inhibit total protein synthesis. Ann Surg (1990) 1.74
Neutralization of gamma interferon and tumor necrosis factor alpha blocks in vivo synthesis of nitrogen oxides from L-arginine and protection against Francisella tularensis infection in Mycobacterium bovis BCG-treated mice. Infect Immun (1993) 1.65
Gamma interferon-induced nitric oxide production reduces Chlamydia trachomatis infectivity in McCoy cells. Infect Immun (1993) 1.50
Cytokine-induced expression of a nitric oxide synthase in rat renal tubule cells. J Clin Invest (1993) 1.10
Necessity and sufficiency of beta interferon for nitric oxide production in mouse peritoneal macrophages. Infect Immun (1994) 1.07
Altered regulation of inducible nitric oxide synthase expression in macrophages from senescent mice. Infect Immun (1996) 1.01
Role of the nitric oxide synthase pathway in inhibition of growth of interferon-sensitive and interferon-resistant Rickettsia prowazekii strains in L929 cells treated with tumor necrosis factor alpha and gamma interferon. Infect Immun (1993) 0.98
A recombinant vaccinia virus encoding inducible nitric oxide synthase is attenuated in vivo. J Virol (1996) 0.88
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The role of tumour necrosis factor-alpha in combination with interferon-gamma or interleukin-1 in the induction of immunosuppressive macrophages because of Mycobacterium avium complex infection. Immunology (1996) 0.82
Nitric oxide-mediated inhibition of the ability of Rickettsia prowazekii to infect mouse fibroblasts and mouse macrophagelike cells. Infect Immun (1998) 0.81
Lymphotoxin inhibits Chlamydia pneumoniae growth in HEp-2 cells. Infect Immun (1999) 0.80
Effects of nitric oxide (NO) synthesis inhibition on antitumor responses during interleukin-2 (IL-2) treatment of mice. Korean J Intern Med (1996) 0.75
Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite. Science (1987) 8.98
Nitric oxide: a cytotoxic activated macrophage effector molecule. Biochem Biophys Res Commun (1988) 8.17
L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells. J Immunol (1987) 6.93
Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr Opin Immunol (1991) 6.92
Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginine. J Immunol (1990) 4.62
Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism. J Immunol (1990) 4.36
Interferon-gamma and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages. Eur J Immunol (1988) 4.04
Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages. J Clin Invest (1988) 3.69
Control of carcinogenesis: a possible role for the activated macrophage. Science (1972) 3.69
EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages. Proc Natl Acad Sci U S A (1990) 2.94
Macrophage tumor killing: influence of the local environment. Science (1977) 2.94
Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages. J Clin Invest (1990) 2.91
Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. Inhibition involves the iron-sulfur prosthetic group and is reversible. J Clin Invest (1986) 2.76
Characterization of the effects of endotoxin on macrophage tumor cell killing. J Immunol (1978) 2.65
Urinary nitrate excretion in relation to murine macrophage activation. Influence of dietary L-arginine and oral NG-monomethyl-L-arginine. J Immunol (1991) 2.60
Resistance to murine tumors conferred by chronic infection with intracellular protozoa, Toxoplasma gondii and Besnoitia jellisoni. J Infect Dis (1971) 2.58
Possible role of macrophage mediated nonspecific cytotoxicity in tumour resistance. Nat New Biol (1972) 2.44
L-arginine-dependent macrophage effector functions inhibit metabolic activity of Mycobacterium leprae. J Immunol (1991) 2.15
Macrophage nonimmunologic recognition: target cell factors related to contact inhibition. Science (1973) 2.09
Evidence for cytokine-inducible nitric oxide synthesis from L-arginine in patients receiving interleukin-2 therapy. J Clin Invest (1992) 2.08
Nitric oxide produced during murine listeriosis is protective. Infect Immun (1994) 1.93
Effect of in vivo inhibition of nitric oxide production in murine leishmaniasis. J Immunol (1993) 1.88
Heterocytolysis by macrophages activated by bacillus Calmette-Guérin: lysosome exocytosis into tumor cells. Science (1974) 1.85
Macrophage fibrinolytic activity: identification of two pathways of plasmin formation by intact cells and of a plasminogen activator inhibitor. Cell (1982) 1.84
Injury of neoplastic cells by murine macrophages leads to inhibition of mitochondrial respiration. J Clin Invest (1980) 1.82
The L-arginine dependent effector mechanism is induced in murine adenocarcinoma cells by culture supernatant from cytotoxic activated macrophages. J Leukoc Biol (1988) 1.72
Degradation of fibrin and elastin by intact human alveolar macrophages in vitro. Characterization of a plasminogen activator and its role in matrix degradation. J Clin Invest (1984) 1.72
Measurement of nitrate and nitrite in biological samples using nitrate reductase and Griess reaction. Methods Enzymol (1996) 1.67
Discrimination between neoplastic and non-neoplastic cells in vitro by activated macrophages. J Natl Cancer Inst (1974) 1.64
Iron depletion: possible cause of tumor cell cytotoxicity induced by activated macrophages. Biochem Biophys Res Commun (1984) 1.64
Endocytosis of red blood cells or haemoglobin by activated macrophages inhibits their tumoricidal effect. Nature (1977) 1.55
Gamma interferon-induced nitric oxide production reduces Chlamydia trachomatis infectivity in McCoy cells. Infect Immun (1993) 1.50
Modulation of macrophage tumoricidal capability by components of normal serum: a central role for lipid. Science (1977) 1.35
In vitro nonimmunologic destruction of cells with abnormal growth characteristics by adjuvant activated macrophages. Proc Soc Exp Biol Med (1972) 1.30
Assembly and regulation of NADPH oxidase and nitric oxide synthase. Curr Opin Immunol (1994) 1.24
Aconitases: a class of metalloproteins highly sensitive to nitric oxide synthesis. Methods Enzymol (1996) 1.19
The macrophage as an antineoplastic surveillance cell: biological perspectives. J Reticuloendothel Soc (1978) 1.15
The role of nitrogen oxides as effector molecules of parasite killing. Parasitol Today (1990) 1.15
Modulation of macrophage tumoricidal capability by polyene antibiotics: support for membrane lipid as a regulatory determinant of macrophage function. Proc Natl Acad Sci U S A (1978) 1.14
Nitric oxide production during murine Lyme disease: lack of involvement in host resistance or pathology. Infect Immun (1995) 1.11
Adjuvant induced resistance to tumor development in mice. Proc Soc Exp Biol Med (1972) 1.10
Antiparasitic effects of nitric oxide in an in vitro murine model of Chlamydia trachomatis infection and an in vivo murine model of Leishmania major infection. Immunol Ser (1994) 1.08
Activated macrophages as cytotoxic effector cells. Transplantation (1975) 1.07
Parana, a new Tacaribe complex virus from Paraguay. Arch Gesamte Virusforsch (1970) 1.03
Macrophage nitric oxide synthesis delays progression of ultraviolet light-induced murine skin cancers. Cancer Res (1993) 1.02
Effects of trypan blue treatment on the immune responses of mice. Infect Immun (1977) 0.99
DNA virus-transformed hamster cell--host effector cell interactions: level of resistance to cytolysis correlated with tumorigenicity. Int J Cancer (1982) 0.97
Use of N-acetyl cysteine to increase intracellular glutathione during the induction of antitumor responses by IL-2. J Immunol (1994) 0.96
Role of activated macrophages in nonspecific resistance to neoplasia. J Reticuloendothel Soc (1976) 0.95
Induction of iron-derived EPR signals in murine cancers by nitric oxide. Evidence for multiple intracellular targets. J Biol Chem (1994) 0.94
Interaction of macrophages with tumor cells. Adv Exp Med Biol (1976) 0.92
Coordinate expression of macrophage procoagulant and fibrinolytic activity in vitro and in vivo. J Immunol (1983) 0.91
Nitric oxide production in murine leishmaniasis: correlation of progressive infection with increasing systemic synthesis of nitric oxide. Am J Trop Med Hyg (1996) 0.88
In vitro modulation of macrophage tumoricidal activity: partial characterization of a macrophage-activating factor(s) in supernatants of NaIO4-treated peritoneal cells. J Reticuloendothel Soc (1979) 0.88
Activated macrophage conditioned medium: identification of the soluble factors inducing cytotoxicity and the L-arginine dependent effector mechanism. J Leukoc Biol (1991) 0.86
Cloned macrophages can be induced to kill tumor cells. J Reticuloendothel Soc (1978) 0.85
Resistance of simian virus 40-transformed hamster cells to the cytolytic effect of activated macrophages: a possible factor in species-specific viral oncogenicity. Proc Natl Acad Sci U S A (1980) 0.83
Nitric oxide production during adjuvant-induced and collagen-induced arthritis. Arthritis Rheum (1996) 0.82
Nitric oxide synthesis contributes to IL-2-induced antitumor responses against intraperitoneal Meth A tumor. J Immunol (1995) 0.82
N omega -monomethyl-L-arginine inhibits nitric oxide production in murine cardiac allografts but does not affect graft rejection. Biochim Biophys Acta (1994) 0.80
Activated macrophage-mediated cytotoxicity: use of the in vitro cytotoxicity assay for study of bioenergetic and biochemical changes that develop in tumor target cells. Methods Enzymol (1986) 0.80
Modulation of plasminogen activator secretion by activated macrophages: influence of serum factors and correlation with tumoricidal potential. Proc Natl Acad Sci U S A (1979) 0.80
Aberrant oxygen metabolism in neoplastic cells injured by cytotoxic macrophages. Adv Exp Med Biol (1985) 0.79
Modulation of the tumoricidal function of activated macrophages by bacterial endotoxin and mammalian macrophage activation factor (s). Adv Exp Med Biol (1979) 0.78
Enhanced macrophage tumoricidal activity and tumor suppression or regression caused by heat-killed Candida albicans. J Natl Cancer Inst (1979) 0.78
Activated macrophage mediated cytotoxicity for transformed target cells. Adv Exp Med Biol (1982) 0.78
Activated macrophages as cytotoxic effector cells. II. Requirement for local persistence of inducing antigen. Transplantation (1975) 0.77
Nitric oxide synthesis in patients with advanced HIV infection. Clin Exp Immunol (1994) 0.77
High-output nitric oxide: weapon against infection? Trends Microbiol (1996) 0.76
Effectiveness and toxicity of protracted nitric oxide synthesis inhibition during IL-2 treatment of mice. J Immunother Emphasis Tumor Immunol (1995) 0.75
A relationship between SV40-transformed cell susceptibility to macrophage killing and tumor induction in rodents. Adv Exp Med Biol (1981) 0.75
Water as a biomaterial. Trans Am Soc Artif Intern Organs (1973) 0.75
Nitric oxide production during adjuvant-induced arthritis is associated with tumor necrosis factor genotype. Transplant Proc (1995) 0.75