Published in J Clin Invest on May 01, 1988
Preparation and study of fragments of single rabbit nephrons. Am J Physiol (1966) 7.29
Transport of p-aminohippuric acid by plasma membrane vesicles isolated from rat kidney cortex. Pflugers Arch (1976) 1.85
Properties of acyl glucuronides: implications for studies of the pharmacokinetics and metabolism of acidic drugs. Drug Metab Rev (1984) 1.57
Volume reabsorption, transepithelial potential differences, and ionic permeability properties in mammalian superficial proximal straight tubules. J Gen Physiol (1974) 1.50
The metabolism of indomethacin in man. J Pharmacol Exp Ther (1972) 1.44
Characteristics of p-aminohippurate transport in proximal renal tubules. Am J Physiol (1969) 1.43
Coupling between proximal tubular transport processes. Studies with ouabain, SITS and HCO3-free solutions. Pflugers Arch (1977) 1.36
Relation between plasma concentration of indomethacin and its effect on prostaglandin synthesis and platelet aggregation in man. Clin Pharmacol Ther (1978) 1.33
Indomethacin: plasma concentrations and protein binding in man. Eur J Clin Pharmacol (1972) 1.28
Effect of strophanthidin on electrolyte content and PAH accumulation of rabbit kidney slices. Am J Physiol (1962) 1.15
Active ion transport in the renal proximal tubule. I. Transport and metabolic studies. J Gen Physiol (1984) 1.04
Renal organic anion transport system: pharmacological, physiological, and biochemical aspects. Pharmacol Rev (1982) 1.03
Effect of cations on transport of weak organic acids in rabbit kidney slices. Am J Physiol (1970) 1.00
Relationship between para-aminohippurate secretion and cellular morphology in rabbit proximal tubules. J Clin Invest (1978) 0.97
Roles of sodium and potassium ions on p-aminohippurate transport in rabbit kidney slices. Biochim Biophys Acta (1975) 0.96
Renal tubular mechanisms of organic solute transport. Kidney Int (1976) 0.90
Temperature dependence of transepithelial potential in isolated perfused rabbit proximal tubules. Am J Physiol (1979) 0.89
Renal transport kinetics of furosemide in the isolated perfused rat kidney. J Pharmacokinet Biopharm (1986) 0.86
Involvement of Na+-K+-ATPase in p-aminohippurate transport by rabbit kidney tissue. J Physiol (1981) 0.85
An energy-dependent, sodium-independent component of active p-aminohippurate transport in rabbit renal cortex. J Physiol (1981) 0.83
Relationship between PAH transport and Na-K-ATPase activity in the rabbit kidney. Am J Physiol (1979) 0.82
Effect of DIDS on renal tubular transport. Am J Physiol (1980) 0.82
Effect of SITS on organic anion transport in the rabbit kidney cortical slice. Am J Physiol (1978) 0.82
Different temperature sensitivity and cation specificity of two distinct D-glucose/Na+ cotransport systems in the intestinal brush-border membrane. Ann N Y Acad Sci (1985) 0.81
Bath and lumen effects of SITS on PAH transport by isolated perfused renal tubules. Am J Physiol (1980) 0.80
Nature of Na+-independent stimulation of renal transport of p-aminohippurate by exogenous metabolites. Biochem Pharmacol (1983) 0.80
Net fluid secretion in proximal straight renal tubules in vitro: role of PAH. Am J Physiol (1974) 0.80
Studies of organic anion and cation transport in isolated segments of proximal tubules. Kidney Int (1982) 0.79
Effects of K, Na, and ouabain on urate and PAH uptake by snake and chicken kidney slices. Am J Physiol (1969) 0.79
Contraluminal para-aminohippurate (PAH) transport in the proximal tubule of the rat kidney. I. Kinetics, influence of cations, anions, and capillary preperfusion. Pflugers Arch (1987) 0.78
Low Na+ effects on PAH transport and permeabilities in isolated snake renal tubules. Am J Physiol (1976) 0.77
Characteristics of renal p-aminohippurate and urate excretion in rabbits. J Lab Clin Med (1986) 0.77
Highly sensitive measurement of indomethacin using a high-performance liquid chromatographic technique combined with post-column in-line hydrolysis. J Chromatogr (1986) 0.77
Sodium-dependence of p-aminohippurate transport by rat kidney cortex slices. Arch Int Pharmacodyn Ther (1979) 0.77
Na+ gradient-dependent p-aminohippurate (PAH) transport in rat basolateral membrane vesicles. J Pharmacol Exp Ther (1983) 0.76
Effect of cyclooxygenase-2 inhibition on renal function in elderly persons receiving a low-salt diet. A randomized, controlled trial. Ann Intern Med (2000) 2.82
Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction. J Clin Invest (1994) 2.55
Improving treatment of late life depression in primary care: a randomized clinical trial. J Am Geriatr Soc (1994) 2.40
Effect of restricting dietary protein on the progression of renal failure in patients with insulin-dependent diabetes mellitus. N Engl J Med (1991) 2.08
Medieval contributions to the search for truth in clinical medicine. Perspect Biol Med (2000) 2.05
Angiotensin II directly stimulates sodium transport in rabbit proximal convoluted tubules. J Clin Invest (1984) 1.93
Open-label randomized trial of torsemide compared with furosemide therapy for patients with heart failure. Am J Med (2001) 1.89
Functional and molecular aspects of renal prostaglandin receptors. J Am Soc Nephrol (1996) 1.75
Factors associated with exacerbation of heart failure include treatment adherence and health literacy skills. Clin Pharmacol Ther (2009) 1.63
Ibuprofen-associated renal impairment in a large general internal medicine practice. Am J Med Sci (1990) 1.61
Intrinsic differences in various segments of the proximal convoluted tubule. J Clin Invest (1976) 1.56
Systemic drug interactions with topical glaucoma medications. Surv Ophthalmol (1991) 1.54
Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet. J Clin Invest (1994) 1.53
Bicarbonate transport in cortical and outer medullary collecting tubules. Am J Physiol (1983) 1.50
Disposition kinetics of ethambutol in man. J Pharmacokinet Biopharm (1980) 1.50
Renal toxicity of the nonsteroidal anti-inflammatory drugs. Annu Rev Pharmacol Toxicol (1993) 1.47
Defining hypercalciuria in nephrolithiasis. Kidney Int (2011) 1.44
The time course of delivery of furosemide into urine: an independent determinant of overall response. Kidney Int (1982) 1.43
Loop diuretics for chronic renal insufficiency: a continuous infusion is more efficacious than bolus therapy. Ann Intern Med (1991) 1.43
Social support and health-related quality of life in chronic heart failure patients. Qual Life Res (2001) 1.42
Prostaglandin E2 inhibits sodium transport in rabbit cortical collecting duct by increasing intracellular calcium. J Clin Invest (1991) 1.39
Anion dependence of rabbit medullary collecting duct acidification. J Clin Invest (1983) 1.39
Effects of CO2 and acetazolamide on bicarbonate and fluid transport in rabbit proximal tubules. Am J Physiol (1981) 1.25
Bumetanide and furosemide in heart failure. Kidney Int (1984) 1.25
Methotrexate disposition following concomitant administration of ketoprofen, piroxicam and flurbiprofen in patients with rheumatoid arthritis. Br J Clin Pharmacol (1994) 1.24
Bioavailability, pharmacokinetics, and pharmacodynamics of torsemide and furosemide in patients with congestive heart failure. Clin Pharmacol Ther (1995) 1.24
PGE2 inhibits AVP-induced water flow in cortical collecting ducts by protein kinase C activation. Am J Physiol (1990) 1.22
Mineralocorticoid modulation of rabbit medullary collecting duct acidification. A sodium-independent effect. J Clin Invest (1983) 1.21
Pharmacokinetics of amantadine hydrochloride in subjects with normal and impaired renal function. Ann Intern Med (1981) 1.21
Analysis of the effect of indomethacin on the response to furosemide in man: effect of dose of furosemide. J Pharmacol Exp Ther (1979) 1.20
Furosemide absorption altered in decompensated congestive heart failure. Ann Intern Med (1985) 1.20
Attenuation of furosemide's diuretic effect by indomethacin: pharmacokinetic evaluation. J Pharmacokinet Biopharm (1979) 1.17
Evidence that separate PGE2 receptors modulate water and sodium transport in rabbit cortical collecting duct. Am J Physiol (1993) 1.17
Characteristics of volume reabsorption in rabbit superficial and juxtamedullary proximal convoluted tubules. J Clin Invest (1979) 1.17
Intratubular albumin blunts the response to furosemide-A mechanism for diuretic resistance in the nephrotic syndrome. J Pharmacol Exp Ther (1990) 1.16
Stereoselective metabolism of ibuprofen in humans: administration of R-, S- and racemic ibuprofen. J Pharmacol Exp Ther (1991) 1.15
A Bayesian feedback method of aminoglycoside dosing. Clin Pharmacol Ther (1985) 1.14
Cytochrome P-450 arachidonic acid epoxygenase. Regulatory control of the renal epoxygenase by dietary salt loading. J Biol Chem (1992) 1.12
Comparison of drug dosing methods. Clin Pharmacokinet (1985) 1.11
The interaction of diltiazem with lovastatin and pravastatin. Clin Pharmacol Ther (1998) 1.11
Effects of ibuprofen, naproxen, and sulindac on prostaglandins in men. Kidney Int (1985) 1.10
Comparison of loop diuretics in patients with chronic renal insufficiency. Kidney Int (1987) 1.10
Pharmacodynamic analysis of the furosemide-probenecid interaction in man. Kidney Int (1979) 1.10
Collagen polymorphism in cultured rat kidney mesangial cells. Lab Invest (1987) 1.09
5,6-EET inhibits ion transport in collecting duct by stimulating endogenous prostaglandin synthesis. Am J Physiol (1995) 1.09
Evidence for glomerular actions of epidermal growth factor in the rat. J Clin Invest (1988) 1.09
In situ hybridization and localization of mRNA for the rabbit prostaglandin EP3 receptor. Kidney Int (1993) 1.08
Dietary modulation of active potassium secretion in the cortical collecting tubule of adrenalectomized rabbits. J Clin Invest (1982) 1.05
Cytochrome P-450 arachidonate metabolites in rat kidney: characterization and hemodynamic responses. Am J Physiol (1990) 1.03
Epidermal growth factor inhibits the hydroosmotic effect of vasopressin in the isolated perfused rabbit cortical collecting tubule. J Clin Invest (1988) 1.03
Interactions of lysyl-bradykinin and antidiuretic hormone in the rabbit cortical collecting tubule. J Clin Invest (1984) 1.03
Variable furosemide absorption and poor predictability of response in elderly patients. Pharmacotherapy (1997) 1.02
Bumetanide and furosemide. Clin Pharmacol Ther (1983) 1.01
The interaction of diltiazem with simvastatin. Clin Pharmacol Ther (2000) 1.01
Epoxyeicosatrienoic acids activate Na+/H+ exchange and are mitogenic in cultured rat glomerular mesangial cells. J Cell Physiol (1990) 1.00
Treatment of severe neonatal infections with cefotaxime. Efficacy and pharmacokinetics. J Pediatr (1982) 1.00
Hormonal regulation of proton secretion in rabbit medullary collecting duct. J Clin Invest (1986) 1.00
Resistance to loop diuretics. Why it happens and what to do about it. Drugs (1985) 0.99
Cytochrome P450 metabolites of arachidonic acid are potent inhibitors of vasopressin action on rabbit cortical collecting duct. J Clin Invest (1989) 0.99
Phorbol myristate acetate, dioctanoylglycerol, and phosphatidic acid inhibit the hydroosmotic effect of vasopressin on rabbit cortical collecting tubule. J Clin Invest (1987) 0.99
Nephron site of effect of nonsteroidal anti-inflammatory drugs on solute excretion in humans. Am J Physiol (1983) 0.99
Kinetics of oral ethambutol in the normal subject. Clin Pharmacol Ther (1977) 0.98
Variability in derived parameters of furosemide pharmacokinetics. J Pharmacokinet Biopharm (1981) 0.98
Pharmacokinetic-dynamic analysis of the indomethacin-furosemide interaction in man. J Pharmacol Exp Ther (1980) 0.98
Differential localization of prostaglandin E receptor subtypes in human kidney. Am J Physiol (1996) 0.98
Effects of albumin/furosemide mixtures on responses to furosemide in hypoalbuminemic patients. J Am Soc Nephrol (2001) 0.97
Luminal prostaglandin E receptors regulate salt and water transport in rabbit cortical collecting duct. Am J Physiol (1995) 0.96
Molecular cloning, expression, and enzymatic characterization of the rat kidney cytochrome P-450 arachidonic acid epoxygenase. J Biol Chem (1993) 0.96
Diuretics: sites and mechanisms of action. Annu Rev Pharmacol Toxicol (1976) 0.95
Stereoselective disposition of flurbiprofen in normal volunteers. Br J Clin Pharmacol (1992) 0.95
Medullary collecting duct acidification. Effects of potassium, HCO3 concentration, and pCO2. J Clin Invest (1984) 0.95
Cellular mechanisms of prostaglandin E2 and vasopressin interactions in the collecting duct. Kidney Int (1990) 0.95
Clinical comparison of cimetidine and ranitidine. Clin Pharmacol Ther (1982) 0.94
Effect of indomethacin on salt and water homeostasis. Clin Pharmacol Ther (1979) 0.94
Furosemide in patients with heart failure: shift in dose-response curves. Clin Pharmacol Ther (1980) 0.94
Drug-drug and drug-disease interactions with nonsteroidal anti-inflammatory drugs. Am J Med (1986) 0.93
Glomerular stereospecific synthesis and hemodynamic actions of 8,9-epoxyeicosatrienoic acid in rat kidney. Am J Physiol (1991) 0.93
Stereoselective disposition of flurbiprofen in uraemic patients. Br J Clin Pharmacol (1992) 0.93
Clinical pharmacology of torasemide, a new loop diuretic. Clin Pharmacol Ther (1987) 0.93
Determination of chloride and bicarbonate permeabilities in proximal convoluted tubules. Am J Physiol (1981) 0.92
Functional characterization of alpha- and beta-intercalated cell types in rabbit cortical collecting duct. Am J Physiol (1991) 0.92
Electrophysiological study of isolated perfused human collecting ducts: Ion dependency of the transepithelial potential difference. J Clin Invest (1976) 0.92
Absorption and disposition of furosemide in congestive heart failure. Kidney Int (1982) 0.92
Functional segmentation of the mammalian nephron. Am J Physiol (1981) 0.92
Plasma protein binding of flurbiprofen: enantioselectivity and influence of pathophysiological status. J Pharmacol Exp Ther (1989) 0.92
Healthcare costs of patients with heart failure treated with torasemide or furosemide. Pharmacoeconomics (2000) 0.92
Cloning and expression of the rabbit prostaglandin EP4 receptor. Am J Physiol (1996) 0.91
Interaction studies with bumetanide and furosemide. Effects of probenecid and of indomethacin on response to bumetanide in man. J Clin Pharmacol (1982) 0.91
Altered permeability in the proximal tubule response to cyclic AMP. Am J Physiol (1979) 0.91
Regulation of net bicarbonate transport in rabbit cortical collecting tubule by peritubular pH, carbon dioxide tension, and bicarbonate concentration. J Clin Invest (1986) 0.90
Vancomycin elimination in patients with burn injury. Clin Pharmacol Ther (1986) 0.90
The effects of a salicylate, ibuprofen, and naproxen on the disposition of methotrexate in patients with rheumatoid arthritis. Eur J Clin Pharmacol (1992) 0.90
Pharmacodynamic considerations in the use of diuretics. Annu Rev Pharmacol Toxicol (1983) 0.90
Acute and chronic effects of nonsteroidal antiinflammatory drugs on glomerular filtration rate in elderly patients. Am J Med Sci (1995) 0.90
The regulation of renal acid secretion: new observations from studies of distal nephron segments. Kidney Int (1986) 0.89
Response to furosemide in chronic renal insufficiency: rationale for limited doses. Clin Pharmacol Ther (1986) 0.88
Ethambutol kinetics in patients with impaired renal function. Am Rev Respir Dis (1986) 0.88
Glomerular responses to platelet-activating factor in the rat: role of thromboxane A2. Am J Physiol (1989) 0.88
PGE2 regulates cAMP production in cultured rabbit CCD cells: evidence for dual inhibitory mechanisms. Am J Physiol (1992) 0.87
Regulation of rabbit medullary collecting duct cell pH by basolateral Na+/H+ and Cl-/base exchange. J Clin Invest (1989) 0.87