Published in Drug Metab Dispos on July 16, 1979
Lipid peroxidation in adrenal and testicular microsomes. Environ Health Perspect (1981) 0.78
Cytosolic factors which affect microsomal lipid peroxidation in lung and liver. Arch Biochem Biophys (1981) 1.22
Ascorbate uptake by isolated rat alveolar macrophages and type II cells. J Appl Physiol Respir Environ Exerc Physiol (1983) 0.85
Changes in adrenocortical function in male and female guinea-pigs during maturation. J Endocrinol (1976) 0.85
Is growth hormone the pituitary feminizing factor mediating the actions of estradiol on hepatic drug and steroid metabolism? Endocrinology (1980) 0.85
Inhibition of hepatic microsomal lipid peroxidation by drug substrates without drug metabolism. Biochem Pharmacol (1980) 0.83
Hepatic drug metabolism in retinol-deficient rats. Biochem Pharmacol (1975) 0.83
Adrenal cortical dysfunction as a basis for experimental hypertensive disease. Circ Res (1969) 0.82
Mechanism of action of spironolactone on adrenocortical function in guinea pigs. J Pharmacol Exp Ther (1976) 0.82
Identification of spironolactone metabolites in plasma and target organs of guinea pigs. Drug Metab Dispos (1994) 0.81
The relationship between chemiluminescence and lipid peroxidation in rat hepatic microsomes. Arch Biochem Biophys (1979) 0.81
Metopirone-induced hypertension in the rat. Endocrinology (1970) 0.81
Changes in mitochondrial and microsomal lipid peroxidation and fatty acid profiles in adrenal glands, testes, and livers from alpha-tocopherol-deficient rats. Free Radic Biol Med (2001) 0.81
Dioxin in soil: bioavailability after ingestion by rats and guinea pigs. Science (1984) 0.80
Binding of spironolactone metabolites in vivo to renal mineralocorticoid receptors in guinea pigs. Pharmacology (1994) 0.80
Relation of canrenone to the actions of spironolactone on adrenal cytochrome P-450 dependent enzymes. Endocrinology (1978) 0.79
Effects of gonadal hormones on adrenocortical secretion of 5 -reduced metabolites of corticosterone in the rat. Endocrinology (1972) 0.79
Dose-dependent actions of thyroxine on hepatic drug metabolism in male and female rats. Biochem Pharmacol (1978) 0.79
Effects of indomethacin administration on hepatic steroid and drug metabolism in male and female rats. Biochem Pharmacol (1978) 0.79
Interaction of estradiol and ACTH in the regulation of adrenal corticosterone production in the rat. Steroids (1974) 0.78
Sex and substrate effects on hepatic corticosteroid metabolism in the rat. Endocrinology (1972) 0.78
Lipid peroxidation in adrenal and testicular microsomes. Environ Health Perspect (1981) 0.78
Species differences in adrenal lipid peroxidation: role of alpha-tocopherol. Free Radic Biol Med (1999) 0.78
Interaction of metyrapone with adrenal microsomal cytochrome P450 in the guinea pig. Biochem Pharmacol (1978) 0.78
Effects of luteinizing hormone and follicle stimulating hormone on hepatic drug metabolism in gonadectomizedmale and female rats. Biochem Pharmacol (1977) 0.78
Ingestion of soil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters hepatic enzyme activities in rats. Fundam Appl Toxicol (1986) 0.78
Requirement of the pituitary gland for gonadal hormone effects on hepatic drug metabolism in rats. J Pharmacol Exp Ther (1979) 0.78
Effects of anterior pituitary hormones on hepatic corticosterone metabolism in rats. Steroids (1974) 0.78
Feminization of the concentrations of hepatic estrogen-binding proteins by ectopic pituitary. Endocrinology (1983) 0.78
Testosterone-induced hypertension in the rat. Endocrinology (1970) 0.78
Feminization of hepatic steroid and drug metabolizing enzymes by growth hormone in male rats. J Endocrinol (1976) 0.78
Some studies on the effect of androgens on adrenal cortical function of rats. Endocrinology (1970) 0.77
Imprinting of hepatic estrogen-binding proteins by neonatal androgens. Endocrinology (1983) 0.77
Chemical suppression of steroidogenesis. Environ Health Perspect (1981) 0.77
Relation of the pituitary gland to the actions of testosterone on hepatic ethylmorphine metabolism in rats. Biochem Pharmacol (1975) 0.77
Role of the steroid 17 alpha-hydroxylase in spironolactone-mediated destruction of adrenal cytochrome P-450. Mol Pharmacol (1991) 0.77
Sex differences in adrenal and hepatic alpha-tocopherol concentrations in rats. Pharmacology (1992) 0.77
Regulation of adrenal and hepatic alpha-tocopherol content by androgens and estrogens. Biochim Biophys Acta (1993) 0.77
Requirement of the pituitary gland for gonadal hormone effects on hepatic corticosteroid metabolism in rats and hamsters. Endocrinology (1973) 0.77
Maturational changes in CYP2D16 expression and xenobiotic metabolism in adrenal glands from male and female guinea pigs. Drug Metab Dispos (2001) 0.77
Effects of ACTH administration on zonation of the guinea pig adrenal cortex. Mol Cell Endocrinol (1998) 0.77
Effects of gonadal hormones on adrenal steroid metabolism in vitro. Steroids (1972) 0.77
Relationship between mitochondrial lipid peroxidation and alpha-tocopherol levels in the guinea-pig adrenal cortex. Biochim Biophys Acta (1988) 0.76
Molecular cloning and sequencing of a guinea pig cytochrome P4502D (CYP2D16): high level expression in adrenal microsomes. Biochem Biophys Res Commun (1995) 0.76
Effects of hypophysectomy and ACTH on adrenocortical function in the rat. Endocrinology (1974) 0.76
Relation of the gonadal hormones to growth hormone actions on hepatic drug metabolism in rats. J Pharmacol Exp Ther (1978) 0.76
Effects of tocopherol depletion on the regional differences in adrenal microsomal lipid peroxidation and steroid metabolism. Endocrinology (1988) 0.76
Metabolic activation of hydralazine by rat liver microsomes. Biochem Pharmacol (1987) 0.76
Interaction of aromatic hydrocarbons and drugs with adrenal microsomal cytochrome P-450 in the guinea pig. Biochem Pharmacol (1976) 0.76
Mechanism of action of spironolactone on cortisol production by guinea pig adrenocortical cells. Mol Cell Endocrinol (1991) 0.76
Destruction of testicular cytochrome P-450 by 7 alpha-thiospironolactone is catalyzed by the 17 alpha-hydroxylase. J Steroid Biochem Mol Biol (1992) 0.76
Differential effects of adrenocorticotropin in vivo on cytochromes P4502D16 and P450c17 in the guinea pig adrenal cortex. Endocrinology (1996) 0.75
Strain differences in adrenal CYP2D16 expression in guinea pigs. Relationship to xenobiotic metabolism. Biochem Pharmacol (1996) 0.75
Inhibition of adrenocortical, mitochondrial and microsomal monooxygenases by SU-10'603, a steroid 17 alpha-hydroxylase inhibitor. J Steroid Biochem (1989) 0.75
Hepatic metabolism of spironolactone. Production of 3-hydroxy-thiomethyl metabolites. Drug Metab Dispos (1995) 0.75
Ascorbate uptake by isolated rat lung cells. J Appl Physiol Respir Environ Exerc Physiol (1981) 0.75
Modulation of thyroid hormone actions on hepatic drug metabolism by androgens and estrogens. Biochem Pharmacol (1985) 0.75
Dose-dependent actions of spironolactone on the inner and outer zones of the guinea pig adrenal cortex. Pharmacology (1992) 0.75
Conversion of spironolactone to 7 alpha-thiomethylspironolactone by hepatic and renal microsomes. Biochem Pharmacol (1987) 0.75
Regional differences in microsomal lipid peroxidation and antioxidant levels in the guinea pig adrenal cortex. J Steroid Biochem (1987) 0.75
Separation and quantitation of hydralazine metabolites by high-performance liquid chromatography. J Chromatogr (1986) 0.75
Sites of action of cadmium in vitro on hepatic, adrenal, and pulmonary microsomal monooxygenases in guinea pigs. Toxicol Appl Pharmacol (1984) 0.75
Adrenal mitochondrial metabolism of spironolactone. Absence of metabolic activation. Biochem Pharmacol (1988) 0.75
Spironolactone inhibition of cortisol production by guinea pig adrenocortical cells. Horm Metab Res (1990) 0.75
Inhibition of hepatic microsomal drug metabolism by the steroid hydroxylase inhibitor SU-10'603. Biochem Pharmacol (1988) 0.75
Metabolism of spironolactone by adrenocortical and hepatic microsomes: relationship to cytochrome P-450 destruction. J Pharmacol Exp Ther (1986) 0.75
Effects of carbon tetrachloride on adrenocortical structure and function in guinea pigs. Toxicol Appl Pharmacol (1984) 0.75
Effects of carbon tetrachloride administration to guinea pigs on cytochromes P-450 and antioxidant levels in the inner and outer zones of the adrenal cortex. Drug Metab Dispos (1990) 0.75
Strain differences in adrenal microsomal steroid metabolism in guinea pigs. J Steroid Biochem Mol Biol (1998) 0.75
The oxidative metabolism of hydralazine by rat liver microsomes. Drug Metab Dispos (1986) 0.75
Regional differences in adrenocortical benzo[a]pyrene metabolism in guinea pigs. Biochem Pharmacol (1984) 0.75
Functional zonation of the guinea pig adrenal cortex: differences in mitochondrial steroid metabolism between the inner and outer zones. Endocrinology (1984) 0.75
Inhibition of adrenal cytochromes P450 by 1-aminobenzotriazole in vitro. Selectivity for xenobiotic metabolism. Biochem Pharmacol (1994) 0.75
Changes in hepatic drug metabolism in alloxan-diabetic male rabbits. Biochem Pharmacol (1986) 0.75
alpha-Tocopherol depletion eliminates the regional differences in adrenal mitochondrial lipid peroxidation. Mol Cell Endocrinol (1989) 0.75
Effects of lipid peroxidation on adrenal microsomal monooxygenases. Biochim Biophys Acta (1983) 0.75
Mitochondrial steroid metabolism in the inner and outer zones of the guinea-pig adrenal cortex. J Steroid Biochem (1985) 0.75
Expression and zonal distribution of CYP2D16 in the guinea pig adrenal cortex: relationship to xenobiotic metabolism. Mol Pharmacol (1996) 0.75
Separation of spironolactone and its biologically active sulfur-containing metabolites by high-performance liquid chromatography. J Chromatogr (1986) 0.75
Correlation of hepatic cytosolic androgen binding proteins with androgen induction of hepatic microsomal ethylmorphine N-demethylase in the rat. J Steroid Biochem (1984) 0.75
Metabolism of 4-chlorobiphenyl by guinea pig adrenocortical and hepatic microsomes. Biochem Pharmacol (1984) 0.75
Spironolactone metabolism in target tissues. Characteristics of deacetylation in kidney, liver, adrenal cortex, and testes. Drug Metab Dispos (1989) 0.75
Studies on the mechanism of action of testosterone on adrenocortical secretion in hypophysectomized rats. J Endocrinol (1978) 0.75
Inhibition of adrenal steroid metabolism by administration of 1-aminobenzotriazole to guinea pigs. J Steroid Biochem Mol Biol (1995) 0.75
Modulation of the effects of ascorbic acid on lipid peroxidation by tocopherol in adrenocortical mitochondria. J Steroid Biochem (1989) 0.75
Effects of organic solvent vehicles on benzo[a]pyrene metabolism in rabbit lung microsomes. Biochem Pharmacol (1986) 0.75
Inhibition of testicular steroid metabolism by administration of 1-aminobenzotriazole to rats. Pharmacology (1998) 0.75
Regional differences in adrenal activation of spironolactone: relationship to steroid 17 alpha-hydroxylase activity. Drug Metab Dispos (1990) 0.75
Localization of CYP2D16 in the guinea pig adrenal cortex by immunohistochemistry and in situ hybridization. Mol Cell Endocrinol (1997) 0.75
Prevention of methylandrostenediol, methyltestosterone and testosterone-induced hypertension in the rat by hypophysectomy. Proc Soc Exp Biol Med (1972) 0.75
Carbon tetrachloride (CCl4) toxicity in the guinea pig adrenal cortex. W V Med J (1983) 0.75
Effects of adrenocorticotropic hormone and dexamethasone on adrenal and hepatic alpha-tocopherol concentrations. Free Radic Biol Med (1999) 0.75
Transport properties of isolated type II alveolar epithelial cells. Am Rev Respir Dis (1983) 0.75
Differences in microsomal steroid metabolism between the inner and outer zones of the guinea pig adrenal cortex. Endocrinology (1985) 0.75
Strain differences in microsomal xenobiotic metabolism by adrenocortical inner and outer zones. Drug Metab Dispos (1985) 0.75