B Malfroy

Author PubWeight™ 52.95‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Extension of life-span with superoxide dismutase/catalase mimetics. Science 2000 3.41
2 The enkephalinase inhibitor thiorphan shows antinociceptive activity in mice. Nature 1980 2.13
3 High-affinity enkephalin-degrading peptidase in brain is increased after morphine. Nature 1978 1.87
4 Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics. J Neurosci 2001 1.86
5 Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier. Proc Natl Acad Sci U S A 1991 1.85
6 Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic brain injury. J Pharmacol Exp Ther 1998 1.73
7 Molecular cloning and amino acid sequence of rat enkephalinase. Biochem Biophys Res Commun 1987 1.58
8 Biological inactivation of enkephalins and the role of enkephalin-dipeptidyl-carboxypeptidase ("enkephalinase") as neuropeptidase. Life Sci 1981 1.29
9 EUK-8, a synthetic superoxide dismutase and catalase mimetic, ameliorates acute lung injury in endotoxemic swine. J Pharmacol Exp Ther 1995 1.21
10 Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model. Neurosci Lett 2001 1.15
11 beta-Amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a synthetic catalytic free radical scavenger. Proc Natl Acad Sci U S A 1996 1.12
12 Salen-manganese complexes are superoxide dismutase-mimics. Biochem Biophys Res Commun 1993 1.07
13 Properties of "enkephalinase" from rat kidney: comparison of dipeptidyl-carboxypeptidase and endopeptidase activities. Biochem Biophys Res Commun 1982 1.03
14 Role of oxidant stress in the adult respiratory distress syndrome: evaluation of a novel antioxidant strategy in a porcine model of endotoxin-induced acute lung injury. Shock 1996 1.01
15 Enkephalin dipeptidyl carboxypeptidase (enkephalinase) activity: selective radioassay, properties, and regional distribution in human brain. J Neurochem 1982 0.99
16 Substance P primes human neutrophil activation: a mechanism for neurological regulation of inflammation. Biochem Biophys Res Commun 1989 0.96
17 Recombinant human enkephalinase (neutral endopeptidase) prevents cough induced by tachykinins in awake guinea pigs. J Clin Invest 1989 0.94
18 Regional distribution of a high-affinity enkephalin-degrading peptidase ('enkephalinase') and effects of lesions suggest localization in the vicinity of opiate receptors in brain. Neurosci Lett 1979 0.91
19 Salen-manganese complexes: combined superoxide dismutase/catalase mimics with broad pharmacological efficacy. Adv Pharmacol 1997 0.91
20 EUK-134, a synthetic superoxide dismutase and catalase mimetic, protects rat kidneys from ischemia-reperfusion-induced damage. Transplantation 1996 0.89
21 Cellular catabolism of recombinant tissue-type plasminogen activator. Identification and characterization of a novel high affinity uptake system on rat hepatocytes. J Biol Chem 1987 0.89
22 Effects of EUK-8, a synthetic catalytic superoxide scavenger, on hypoxia- and acidosis-induced damage in hippocampal slices. Neuropharmacology 1994 0.89
23 Oxidative signalling and inflammatory pathways in Alzheimer's disease. Biochem Soc Symp 2001 0.88
24 The bradykinin analog RMP-7 increases intracellular free calcium levels in rat brain microvascular endothelial cells. J Pharmacol Exp Ther 1994 0.88
25 Brain-specific polypeptide 1B236 exists in multiple molecular forms. Proc Natl Acad Sci U S A 1985 0.87
26 Purification and substrate specificity of rat kidney "enkephalinase". Life Sci 1983 0.87
27 Effects of bombesin on human small cell lung cancer cells: evidence for a subset of bombesin non-responsive cell lines. J Cell Biochem 1989 0.85
28 Characterization of endopeptidase 3.4.24.11 ("enkephalinase") activity in human plasma and cerebrospinal fluid. Biochem Pharmacol 1990 0.85
29 EUK-8 a synthetic catalytic scavenger of reactive oxygen species protects isolated iron-overloaded rat heart from functional and structural damage induced by ischemia/reperfusion. Cardiovasc Drugs Ther 1996 0.84
30 Enkephalinase from rat kidney. Purification, characterization, and study of substrate specificity. J Biol Chem 1984 0.84
31 Comparison of dipeptidyl carboxypeptidase and endopeptidase activities in the three enkephalin-hydrolysing metallopeptidases: "angiotensin-converting enzyme", thermolysin and "enkephalinase". Biochem Biophys Res Commun 1985 0.84
32 Expression of enzymatically active enkephalinase (neutral endopeptidase) in mammalian cells. J Cell Biochem 1989 0.84
33 Endorphins and endorphin receptors in striatum: relationships with dopaminergic neurons. Adv Biochem Psychopharmacol 1978 0.82
34 Preferential cleavage of amino- and carboxyl-terminal oligopeptides from vasoactive intestinal polypeptide by human recombinant enkephalinase (neutral endopeptidase, EC 3.4.24.11). Biochem Biophys Res Commun 1989 0.82
35 Role of oxidant stress and iron delocalization in acidosis-induced intestinal epithelial hyperpermeability. Shock 1997 0.82
36 Is 'enkephalinase' identical with 'angiotensin-converting enzymes'? Eur J Pharmacol 1979 0.80
37 Opioid peptides: aspects of their origin, release and metabolism. J Exp Biol 1980 0.79
38 Enkephalin metabolism and its inhibition. Biochem Soc Trans 1985 0.79
39 Brain-specific gene expression. Biochem Soc Symp 1986 0.78
40 Elevated synovial tissue concentration of the common acute lymphoblastic leukaemia antigen (CALLA)-associated neutral endopeptidase (3.4.24.11) in human chronic arthritis. Immunology 1990 0.78
41 New substrates for enkephalinase (neutral endopeptidase) based on fluorescence energy transfer. Biochem Biophys Res Commun 1987 0.78
42 Free radicals in reperfusion-induced arrhythmias: study with EUK 8, a novel nonprotein catalytic antioxidant. Free Radic Biol Med 1996 0.78
43 Properties variations and possible synaptic functions of "enkephalinase": a newly characterised dipeptidyl carboxypeptidase. Adv Biochem Psychopharmacol 1980 0.77
44 "Enkephalinase", a newly characterised dipeptidyl carboxypeptidase: properties and possible role in enkephalinergic transmission. Int J Neurol 1980 0.77
45 Fluorescent enkephalin derivatives with biological activity. Biochem Biophys Res Commun 1978 0.77
46 Substance P contracts the human iris sphincter: possible modulation by endogenous enkephalinase. Regul Pept 1990 0.77
47 6,6'-Bis(2-hydroxyphenyl)-2,2'-bipyridine manganese(III) complexes: a novel series of superoxide dismutase and catalase mimetics. Bioorg Med Chem Lett 2001 0.77
48 Oxidative neuropathology and putative chemical entities for Alzheimer's disease: neuroprotective effects of salen-manganese catalytic anti-oxidants. Neurotox Res 2000 0.76
49 Vasodilatory effects of a salen-manganese complex with potent oxyradical scavenger activities. J Vasc Res 1997 0.76
50 A lipidated anti-Tat antibody enters living cells and blocks HIV-1 viral replication. J Acquir Immune Defic Syndr Hum Retrovirol 1997 0.76
51 Localization of enkephalinase mRNA in rat brain by in situ hybridization: comparison with immunohistochemical localization of the protein. Neuropeptides 1989 0.76
52 Protective effect of the superoxide scavenger EUK8 against ultrastructural alterations induced by ischemia and reperfusion in isolated rat hearts. Nutrition 1996 0.75
53 Effects of cycloheximide and/or morphine on enkephalin levels in mouse striatum. Eur J Pharmacol 1978 0.75
54 Disappearance of energy-transfer as a tool for fluorimetric study of the degradation of enkephalins by aminopeptidase activity from mouse brain. Biochem Biophys Res Commun 1979 0.75
55 [Use of opiate receptor antagonists and peptidase inhibitors for studying central morphinomimetic peptidergic systems]. Ann Endocrinol (Paris) 1983 0.75
56 Drug delivery to the brain using an anti-transferrin receptor antibody. NIDA Res Monogr 1992 0.75
57 Recombinant enkephalinase effectively inhibits substance P-induced miosis in the rabbit eye cup model. Curr Eye Res 1990 0.75
58 Enkephalin dipeptidyl carboxypeptidase ("enkephalinase"): assay, properties, and distribution in human brain and exploration of the active site. Adv Biochem Psychopharmacol 1982 0.75
59 Conformation and biological activities of hexapeptides related to enkephalins: respective roles of the ammonium and hydroxyl groups of tyrosine. Life Sci 1979 0.75