Published in Acta Paediatr Scand Suppl on January 01, 1977
Small is beautiful: insulin-like growth factors and their role in growth, development, and cancer. J Clin Oncol (2010) 1.68
Characterization of proinsulin- and proglucagon-converting activities in isolated islet secretory granules. J Cell Biol (1981) 1.26
Evolutionary origins of vertebrate hormones: substances similar to mammalian insulins are native to unicellular eukaryotes. Proc Natl Acad Sci U S A (1980) 1.08
Histopathological classification of nonantral gastric endocrine growths in man. Digestion (1988) 1.85
The basic structural lesion of persistent neonatal hypoglycaemia with hyperinsulinism: deficiency of pancreatic D cells or hyperactivity of B cells? Diabetologia (1984) 1.35
Deregulation of cyclin E and D1 in breast cancer is associated with inactivation of the retinoblastoma protein. Oncogene (1997) 1.33
Immunohistochemical distribution of the three predominant secretory proteins in the parenchyma of hyperplastic and neoplastic prostate glands. Prostate (1988) 1.25
Role of zinc in insulin biosynthesis. Some possible zinc-insulin interactions in the pancreatic B-cell. Diabetologia (1980) 1.22
The course of neuroendocrine differentiation in prostatic carcinomas. An immunohistochemical study testing chromogranin A as an "endocrine marker". Pathol Res Pract (1989) 1.21
Cyclin E overexpression, a negative prognostic factor in breast cancer with strong correlation to oestrogen receptor status. Br J Cancer (1996) 1.19
Messenger RNA sequence and primary structure of preproinsulin in a primitive vertebrate, the Atlantic hagfish. J Biol Chem (1981) 1.14
Prevention of relapse of reflux esophagitis after endoscopic healing: the efficacy and safety of omeprazole compared with ranitidine. Scand J Gastroenterol (1991) 1.12
Neuroendocrine tumors of the gastrointestinal tract. Pathol Res Pract (1988) 1.10
G1-S transition defects occur in most breast cancers and predict outcome. Breast Cancer Res Treat (1999) 1.10
Telomerase activity is associated with cell cycle deregulation in human breast cancer. Cancer Res (1997) 1.09
Structural lability of zinc-containing secretion granules of pancreatic beta-cells after exposure to hydrogen sulphide. Diabetologia (1968) 1.09
Re: Editorial entitled 'The origin of gut and pancreatic neuroendocrine (APUD) cells--the last word?'. J Pathol (1999) 1.08
Risk factors for local recurrence after breast-conserving surgery. Br J Surg (2003) 1.08
Persistent neonatal hypoglycaemia. A clinical and histopathological study of three cases treated with diazoxide and subtotal pancreatectomy. Acta Pathol Microbiol Scand A (1975) 1.06
Local recurrence in the breast after conservative surgery--a study of prognosis and prognostic factors in 391 women. Eur J Cancer (2002) 1.05
Clinical significance of elevated serum chromogranin A levels. Scand J Gastroenterol (2004) 1.02
Peptide-hormone- and serotonin-immunoreactive tumour cells in carcinoma of the prostate. Pathol Res Pract (1987) 1.02
Prognostic value of DNA content in colorectal carcinoma. A flow cytometric study with some methodologic aspects. Cancer (1987) 0.97
Methylation of the p16(Ink4a) tumor suppressor gene 5'-CpG island in breast cancer. Cancer Lett (2001) 0.97
Penicillamine-induced normalization of clinical signs, and liver morphology and histochemistry in a case of Wilson's disease. Pediatrics (1970) 0.95
Immunohistochemical evidence of gastro-entero-pancreatic neurohormonal peptides of vertebrate type in the nervous system of the larva of a dipteran insect, the hoverfly, Eristalis aeneus. Regul Pept (1980) 0.94
Pattern of distribution and prognostic value of angiogenesis in pancreatic duct carcinoma: a semiquantitative immunohistochemical study of 45 patients. Pancreas (2001) 0.92
Serum antibodies against p53 in relation to cancer risk and prognosis in breast cancer: a population-based epidemiological study. Br J Cancer (1999) 0.92
Hepatomas and other neoplasms in the atlantic hagfish (Myxine glutinosa): a histopathologic and chemical study. Ann N Y Acad Sci (1978) 0.92
IGF-I in human breast cancer: low differentiation stage is associated with decreased IGF-I content. Eur J Endocrinol (2002) 0.91
Pancreatic morphology and blood glucose level in rats at various intervals after duct ligation. Virchows Arch A Pathol Pathol Anat (1968) 0.91
Tissue fixation methods alter the immunohistochemical demonstrability of synaptophysin. Ultrastruct Pathol (1989) 0.91
Intratumoral variations in DNA ploidy and s-phase fraction in human breast cancer. Anal Cell Pathol (2001) 0.91
Ultrastructural localization of insulin-like growth factor-2 (IGF-2) to the secretory granules of insulin cells: a study in normal and diabetic (GK) rats. Ultrastruct Pathol (1997) 0.90
Neuroendocrine (ECL cell) differentiation of spontaneous gastric carcinomas of cotton rats (Sigmodon hispidus). Lab Anim Sci (1999) 0.90
Cyclin E dependent kinase activity in human breast cancer in relation to cyclin E, p27 and p21 expression and retinoblastoma protein phosphorylation. Oncogene (1999) 0.89
Clinical and histopathological tumour progression in ECL cell carcinoids ("ECLomas"). APMIS (1999) 0.89
Peptide-hormone- and serotonin-immunoreactive cells in normal and hyperplastic prostate glands. Pathol Res Pract (1986) 0.87
A glucagon-like peptide, structurally related to mammalian oxyntomodulin, from the pancreas of a holocephalan fish, Hydrolagus colliei. Biochem J (1987) 0.87
Evolution of the insulin gene superfamily. Sequence of a preproinsulin-like growth factor cDNA from the Atlantic hagfish. J Biol Chem (1991) 0.86
Dogfish insulin. Primary structure, conformation and biological properties of an elasmobranchial insulin. Eur J Biochem (1983) 0.86
Consequences of axillary recurrence after conservative breast surgery. Br J Surg (2002) 0.86
The primary structure of ratfish insulin reveals an unusual mode of proinsulin processing. FEBS Lett (1986) 0.85
Insulin and other islet hormones (somatostatin, glucagon and PP) in the neuroendocrine system of some lower vertebrates and that of invertebrates--a minireview. Horm Metab Res (1988) 0.84
Neurohormonal peptides in endocrine tumors of the pancreas, stomach, and upper small intestine: I. An immunohistochemical study of 27 cases. Ultrastruct Pathol (1983) 0.84
Comparative aspects of the immunology and biology of insulin. Diabetologia (1967) 0.84
Preserved beta-cell density in the endocrine pancreas of young, spontaneously diabetic Goto-Kakizaki (GK) rats. Pancreas (1995) 0.83
Zinc and manganese contents of micro-dissected pancreatic islets of some rodents. A microchemical study in adult and newborn guinea pigs, rats, Chinese hamsters and spiny mice. Acta Endocrinol (Copenh) (1977) 0.83
Gut-islet endocrinology-some evolutionary aspects. Invest Cell Pathol (1980) 0.83
Immunohistochemical investigations of neuropeptides in the brain, corpora cardiaca, and corpora allata of an adult lepidopteran insect, Manduca sexta (L). Cell Tissue Res (1983) 0.83
The isolation, purification and amino-acid sequence of insulin from the teleost fish Cottus scorpius (daddy sculpin). Eur J Biochem (1986) 0.83
Studies on the conversion of proinsulin to insulin. II. Evidence for a chymotrypsin-like cleavage in the connecting peptide region of insulin precursors in the rat. J Biol Chem (1973) 0.83
Polypeptide YY- and neuropeptide Y-immunoreactive cells and nerves in the endocrine and exocrine pancreas of some vertebrates: an onto- and phylogenetic study. Histochem J (1987) 0.82
DNA ploidy pattern of parathyroid parenchymal cells in renal secondary hyperparathyroidism with relapse. Anal Cell Pathol (1991) 0.82
Time trends in the results of breast conservation in 4694 women. Eur J Cancer (2001) 0.82
Openers of ATP-dependent K+-channels protect against a signal-transduction-linked and not freely reversible defect of insulin secretion in a rat islet transplantation model of Type 2 diabetes. Diabetologia (2004) 0.82
Immunohistochemical evidence of peptide hormones in endocrine tumors of the rectum. Cancer (1981) 0.82
Ectopic pregnancy in the liver. Report of a case and angiographic findings. Acta Chir Scand (1983) 0.81
Increased amounts of a high molecular weight insulin-like growth factor II (IGF-II) peptide and IGF-II messenger ribonucleic acid in pancreatic islets of diabetic Goto-Kakizaki rats. Endocrinology (1996) 0.81
Synaptophysin. A new marker for pancreatic neuroendocrine tumors. Am J Surg Pathol (1987) 0.81
Spontaneous ECLomas in cotton rats (Sigmodon hispidus): tumours occurring in hypoacidic/hypergastrinaemic animals with normal parietal cells. Carcinogenesis (2000) 0.81
Effects of hagfish insulin in the atlantic hagfish, Myxine glutinosa. The in vivo metabolism of [14C]glucose and [14C]leucine and studies on starvation and glucose-loading. Gen Comp Endocrinol (1982) 0.80
Qualitative and quantitative morphology of rat pancreatic islet tissue five weeks after ligation of the pancreatic ducts. Acta Soc Med Ups (1967) 0.80
Phylogenetic aspects of somatostatin in the gastroenteropancreatic (GEP) endocrine system. Metabolism (1978) 0.80
Insulin assays and light microscopical studies of digestive organs in protostomian and deuterostomian species and in coelenterates. Gen Comp Endocrinol (1971) 0.80
Immunohistochemical, morphometric, and clinical studies of the pancreatic islets in infants with persistent neonatal hypoglycemia of familial type with hyperinsulinism and nesidioblastosis. Acta Biol Med Ger (1981) 0.80
Endocrine tumors of the ileum. Cytochemical and clinical aspects. Pathol Res Pract (1985) 0.80
Identification of IGF-1 receptors in primitive vertebrates. Regul Pept (1993) 0.80
Neurohormonal peptides in ovarian carcinoids: an immunohistochemical study of 81 primary carcinoids and of intraovarian metastases from six mid-gut carcinoids. Cancer (1982) 0.80
Surface ultrastructure of the small intestine mucosa in children with celiac disease. I. Untreated disease and effects of long-term gluten elimination and challenge. Ultrastruct Pathol (1984) 0.79
Characterization of an amidated form of pancreatic polypeptide from the daddy sculpin (Cottus scorpius). Regul Pept (1986) 0.79
Vasoactive intestinal polypeptide (VIP) in epithelial cells of the gut mucosa of an elasmobranchian cartilaginous fish, the ray. Endocrinol Jpn (1980) 0.79
Chromogranin A immunoreactivity compared with argyrophilia, calcitonin immunoreactivity, and amyloid as tumour markers in the histopathological diagnosis of medullary (C-cell) thyroid carcinoma. Pathol Res Pract (1992) 0.79
Structural and crystallographic observations on hagfish insulin. Nature (1974) 0.79
Ultrastructural localization of synaptophysin to the secretory granules of normal glucagon and insulin cells in human islets of Langerhans. Ultrastruct Pathol (1991) 0.79
Tumor pathology of the hagfish, Myxine glutinosa, and the river lamprey, Lampetra fluviatilis. A light-microscopical study with particular reference to the occurrence of primary liver carcinoma, islet-cell tumors, and epidermoid cysts of the skin. Prog Exp Tumor Res (1976) 0.79
Nuclear DNA patterns and survival in metastasizing ileal carcinoids. World J Surg (1987) 0.79
Paragangliomas: neuroendocrine features and cytometric DNA distribution patterns. A clinico-pathological study of 22 cases. Virchows Arch A Pathol Anat Histopathol (1991) 0.78
Static and flow cytometric DNA analysis compared to histologic prognostic factors in a cohort of stage T2 breast cancer. Eur J Surg Oncol (1990) 0.78
Immunohistochemical, morphometric, and ultrastructural investigations of the early development of insulin, somatostatin, glucagon, and PP cells in foetal human pancreas. Diabetes Res (1989) 0.78
The insulin receptor and insulin of the Atlantic hagfish. Extraordinary conservation of binding specificity and negative cooperativity in the most primitive vertebrate. Diabetes (1979) 0.78
Breast carcinoma growth rate described by mammographic doubling time and S-phase fraction. Correlations to clinical and histopathologic factors in a screened population. Cancer (1992) 0.78
Effects of mammalian insulin on blood glucose level, glucose tolerance, and glycogen content of musculature and hepatopancreas in a gastropod mollusk, Strophocheilus oblongus. Gen Comp Endocrinol (1976) 0.77
Destruction of pancreatic beta cells in rats by complete Freund's adjuvant combined with non-diabetogenic doses of streptozotocin. Diabetes Res (1987) 0.77
Occurrence of neurotensin-immunoreactive cells in the digestive tract of lower vertebrates and deuterostomian invertebrates. A correlated immunohistochemical and radioimmunochemical study. Cell Tissue Res (1980) 0.77
Starfish insulin. Can J Biochem (1965) 0.77
Some histological, histochemical, and ultrastructural studies and hormone assays in a transplantable islet carcinoma of the Syrian hamster. Acta Pathol Microbiol Scand (1969) 0.77
Neuroendocrine background of the pathology of the islets of Langerhans. A minireview with particular reference to synaptophysin and chromogranin A as neuroendocrine markers and to the ontogeny of argyrophil insulin immunoreactive cells in the rabbit. Exp Clin Endocrinol (1987) 0.77
A high-molecular IGF-2 immunoreactive peptide (pro-IGF-2?) in the insulin cells of the islets of Langerhans in pancreas of man and rat. Regul Pept (1993) 0.77
Immunocytochemical studies of the evolution of islet hormones. J Histochem Cytochem (1979) 0.77
Phylogenetic aspects of pancreastatin- and chromogranin-like immunoreactive cells in the gastro-entero-pancreatic neuroendocrine system of vertebrates. Gen Comp Endocrinol (1991) 0.77
Blood flow to the pancreatic islet parenchyma of the Atlantic hagfish (Myxine glutinosa). Horm Metab Res (1998) 0.77
Immunocytochemical evidence for the occurrence of insulin in the frontal ganglion of a Lepidopteran insect, the tobacco hornworm moth, Manduca sexta L. Gen Comp Endocrinol (1984) 0.77
Some phylogenetical aspects on the occurrence of somatostatin in the gastro-entero pancreatic endocrine system. A histological and immunocytochemical study, combined with quantitative radioimmunological assays of tissue extracts. Arch Histol Jpn (1977) 0.77