E Vuorio

Author PubWeight™ 127.40‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Predisposition to familial osteoarthrosis linked to type II collagen gene. Lancet 1989 2.43
2 Localization of types I, II, and III collagen mRNAs in developing human skeletal tissues by in situ hybridization. J Cell Biol 1987 2.41
3 Characterization of primary cultures of chondrocytes from type II collagen/beta-galactosidase transgenic mice. Matrix Biol 1994 2.12
4 A standardized experimental fracture in the mouse tibia. J Orthop Res 1993 1.75
5 Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs. Biochim Biophys Acta 1991 1.67
6 Mouse type II collagen gene. Complete nucleotide sequence, exon structure, and alternative splicing. J Biol Chem 1991 1.67
7 Stage-and tissue-specific expression of a Col2a1-Cre fusion gene in transgenic mice. Matrix Biol 2001 1.55
8 Collagenase-3 (MMP-13) is expressed by hypertrophic chondrocytes, periosteal cells, and osteoblasts during human fetal bone development. Dev Dyn 1997 1.44
9 Reduced amounts of cartilage collagen fibrils and growth plate anomalies in transgenic mice harboring a glycine-to-cysteine mutation in the mouse type II procollagen alpha 1-chain gene. Proc Natl Acad Sci U S A 1991 1.37
10 Construction and partial characterization of two recombinant cDNA clones for procollagen from chicken cartilage. Nucleic Acids Res 1982 1.35
11 Coordinated regulation of type I and type III collagen production and mRNA levels of pro alpha 1(I) and pro alpha 2(I) collagen in cultured morphea fibroblasts. Arch Dermatol Res 1987 1.35
12 The mouse collagen X gene: complete nucleotide sequence, exon structure and expression pattern. Biochem J 1993 1.28
13 Normal long bone growth and development in type X collagen-null mice. Nat Genet 1994 1.26
14 Interleukin-1 increases collagen production and mRNA levels in cultured skin fibroblasts. Biochim Biophys Acta 1987 1.25
15 Enhanced expression of TGF-beta and c-fos mRNAs in the growth plates of developing human long bones. Development 1988 1.25
16 Identification of fibroblasts responsible for increased collagen production in localized scleroderma by in situ hybridization. J Invest Dermatol 1988 1.21
17 A metaphyseal defect model of the femur for studies of murine bone healing. Bone 2001 1.19
18 Mouse cathepsin K: cDNA cloning and predominant expression of the gene in osteoclasts, and in some hypertrophying chondrocytes during mouse development. FEBS Lett 1996 1.18
19 Chondrodysplasia in transgenic mice harboring a 15-amino acid deletion in the triple helical domain of pro alpha 1(II) collagen chain. J Cell Biol 1992 1.16
20 Localization of the expression of types I, III, and IV collagen, TGF-beta 1 and c-fos genes in developing human calvarial bones. Dev Biol 1988 1.15
21 Characterization of trimethoprim resistance by use of probes specific for transposon Tn7. Antimicrob Agents Chemother 1984 1.10
22 Systemic versus cartilage-specific expression of a type II collagen-specific T-cell epitope determines the level of tolerance and susceptibility to arthritis. Proc Natl Acad Sci U S A 1996 1.10
23 Construction of a human pro alpha 1(III) collagen cDNA clone and localization of type III collagen expression in human fetal tissues. Matrix 1989 1.08
24 Developmental expression of a type II collagen/beta-galactosidase fusion gene in transgenic mice. Dev Dyn 1995 1.06
25 Role of cathepsin K in normal joints and in the development of arthritis. Curr Drug Targets 2007 1.06
26 Accelerated turnover of metaphyseal trabecular bone in mice overexpressing cathepsin K. J Bone Miner Res 2001 1.05
27 Comparative effects of interleukin-1 and tumor necrosis factor-alpha on collagen production and corresponding procollagen mRNA levels in human dermal fibroblasts. J Invest Dermatol 1991 1.05
28 Human pro alpha 1(I) collagen: cDNA sequence for the C-propeptide domain. Nucleic Acids Res 1988 1.04
29 Localization of type I and III collagen and fibronectin production in injured gastrocnemius muscle. Lab Invest 1991 1.04
30 Expression of Sox9 and type IIA procollagen during attempted repair of articular cartilage damage in a transgenic mouse model of osteoarthritis. Arthritis Rheum 2001 1.03
31 Assembly of cartilage collagen fibrils is disrupted by overexpression of normal type II collagen in transgenic mice. Proc Natl Acad Sci U S A 1993 1.02
32 Histomorphometric and molecular biologic comparison of bioactive glass granules and autogenous bone grafts in augmentation of bone defect healing. J Biomed Mater Res 1997 1.01
33 Increased type I collagen mRNA levels in cultured scleroderma fibroblasts. Biochim Biophys Acta 1984 1.01
34 Identification of messenger RNA for human type II collagen. FEBS Lett 1984 1.01
35 Analysis of aggrecan and tenascin gene expression in mouse skeletal tissues by northern and in situ hybridization using species specific cDNA probes. Biochim Biophys Acta 1994 1.01
36 Antisense RNA inhibition of cathepsin L expression reduces tumorigenicity of malignant cells. Eur J Cancer 2000 1.00
37 Up-regulation of cartilage oligomeric matrix protein at the onset of articular cartilage degeneration in a transgenic mouse model of osteoarthritis. Arthritis Rheum 2000 0.99
38 Differential expression of myc, max and RB1 genes in human gliomas and glioma cell lines. Br J Cancer 1994 0.98
39 Expression of mRNAs for collagens and other matrix components in dedifferentiating and redifferentiating human chondrocytes in culture. FEBS Lett 1989 0.96
40 Synthesis of underpolymerized hyaluronic acid by fibroblasts cultured from rheumatoid and non-rheumatoid synovitis. Rheumatol Int 1982 0.96
41 Conservation of the sizes of 53 introns and over 100 intronic sequences for the binding of common transcription factors in the human and mouse genes for type II procollagen (COL2A1). Biochem J 1995 0.96
42 Expression of the myc proto-oncogenes in developing human fetal brain. Oncogene 1990 0.95
43 Determination of the single polyadenylation site of the human pro alpha 1(II) collagen gene. Nucleic Acids Res 1987 0.95
44 Cathepsin expression during skeletal development. Biochim Biophys Acta 1999 0.95
45 Coordinate patterns of expression of type I and III collagens during mouse development. Matrix Biol 1995 0.94
46 Structural analysis of the regulatory elements of the type-II procollagen gene. Conservation of promoter and first intron sequences between human and mouse. Biochem J 1992 0.94
47 Regulation of extracellular matrix genes during fracture healing in mice. Clin Orthop Relat Res 1993 0.94
48 Elevated pro alpha 2(I) collagen mRNA levels in cultured scleroderma fibroblasts result from an increased transcription rate of the corresponding gene. FEBS Lett 1987 0.93
49 Expression of mRNAs coding for the alpha 1 chain of type XIII collagen in human fetal tissues: comparison with expression of mRNAs for collagen types I, II, and III. J Cell Biol 1989 0.93
50 Activation of type I collagen genes in cultured scleroderma fibroblasts. J Cell Biochem 1985 0.93
51 Expression of cathepsins B, H, K, L, and S and matrix metalloproteinases 9 and 13 during chondrocyte hypertrophy and endochondral ossification in mouse fracture callus. Calcif Tissue Int 2000 0.93
52 In situ localization of collagen production by chondrocytes and osteoblasts in fracture callus. J Bone Joint Surg Am 1989 0.92
53 Type X collagen, a natural component of mouse articular cartilage: association with growth, aging, and osteoarthritis. Arthritis Rheum 1998 0.92
54 Lifelong voluntary joint loading increases osteoarthritis in mice housing a deletion mutation in type II procollagen gene, and slightly also in non-transgenic mice. Ann Rheum Dis 2002 0.92
55 Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human chondrosarcomas. APMIS 2001 0.92
56 Autoimmune recognition of cartilage collagens. Ann Med 1993 0.91
57 Evidence for insufficient chondrocytic differentiation during repair of full-thickness defects of articular cartilage. Matrix Biol 1996 0.91
58 Construction and identification of a cDNA clone for human type II procollagen mRNA. Biochem J 1985 0.91
59 Epidermal growth factor increases collagen production in granulation tissue by stimulation of fibroblast proliferation and not by activation of procollagen genes. Biochem J 1987 0.90
60 Growth-dependent modulation of type I collagen production and mRNA levels in cultured human skin fibroblasts. Biochim Biophys Acta 1990 0.90
61 Expression profiles of mRNAs for osteoblast and osteoclast proteins as indicators of bone loss in mouse immobilization osteopenia model. J Bone Miner Res 1999 0.90
62 Age-dependent changes in the expression of matrix components in the mouse eye. Exp Eye Res 2001 0.90
63 Comparison on collagen gene expression in the developing chick embryo tendon and heart. Tissue and development time-dependent action of dexamethasone. Biochim Biophys Acta 1991 0.90
64 Type I collagen messenger RNA levels in experimental granulation tissue and silicosis in rats. Med Biol 1986 0.89
65 The N-myc proto-oncogene and IGF-II growth factor mRNAs are expressed by distinct cells in human fetal kidney and brain. J Cell Biol 1989 0.89
66 Expression of osteonectin, decorin, and transforming growth factor-beta 1 genes in fibroblasts cultured from patients with systemic sclerosis and morphea. J Rheumatol 1991 0.89
67 Differential expression of fibrillar collagen genes during callus formation. Biochem Biophys Res Commun 1987 0.88
68 Polymorphic restriction sites of type II collagen gene: their location and frequencies in the Finnish population. Hum Hered 1988 0.87
69 Characterization of recombinant human type IX collagen. Association of alpha chains into homotrimeric and heterotrimeric molecules. J Biol Chem 1999 0.87
70 Accelerated up-regulation of L-Sox5, Sox6, and Sox9 by BMP-2 gene transfer during murine fracture healing. J Bone Miner Res 2001 0.86
71 Localization of osteonectin expression in human fetal skeletal tissues by in situ hybridization. Calcif Tissue Int 1989 0.86
72 Cysteine proteinases in chondrosarcomas. Matrix Biol 2001 0.85
73 Specific hybridization probes for mouse alpha 2(IX) and alpha 1(X) collagen mRNAs. Biochim Biophys Acta 1992 0.85
74 Abnormal craniofacial morphology and cartilage structure in transgenic mice harboring a Gly --> Cys mutation in the cartilage-specific type II collagen gene. J Craniofac Genet Dev Biol 1993 0.85
75 Synthesis of laminin and type IV collagen by trophoblastic cells and fibroblastic stromal cells in the early human placenta. Lab Invest 1991 0.85
76 Combined effect of BMP-2 gene transfer and bioactive glass microspheres on enhancement of new bone formation. J Biomed Mater Res A 2005 0.84
77 Activation of chondrogenesis in response to injury in normal and transgenic mice with cartilage collagen mutations. Osteoarthritis Cartilage 2001 0.84
78 Cloning of cDNA for rat pro alpha 1(III) collagen mRNA. Different expression patterns of type I and type III collagen and fibronectin genes in experimental granulation tissue. Biochim Biophys Acta 1994 0.84
79 Differential expression patterns of cathepsins B, H, K, L and S in the mouse ovary. Mol Hum Reprod 2001 0.84
80 Localization of protamine 1 mRNA in different stages of the cycle of the rat seminiferous epithelium. J Cell Biol 1988 0.84
81 Temporospatial expression of tissue inhibitors of matrix metalloproteinases-1, -2 and -3 during development, growth and aging of the mouse skeleton. Histochem Cell Biol 2000 0.84
82 Connective tissue diseases: mutations of collagen genes. Ann Clin Res 1986 0.84
83 Complete genomic structure of the mouse cathepsin K gene (Ctsk) and its localization next to the Arnt gene on mouse chromosome 3. Matrix Biol 1999 0.83
84 Ocular abnormalities in transgenic mice harboring mutations in the type II collagen gene. Eur J Ophthalmol 1997 0.83
85 Cyclic expression of mRNA transcripts for connective tissue components in the mouse ovary. Mol Hum Reprod 1999 0.83
86 Molecular cloning of the human alpha 2(IX) collagen cDNA and assignment of the human COL9A2 gene to chromosome 1. FEBS Lett 1993 0.83
87 Expression patterns of cathepsins B, H, K, L and S in the human endometrium. Mol Hum Reprod 2001 0.83
88 Syndecan-1 expression is upregulated in degenerating articular cartilage in a transgenic mouse model for osteoarthritis. Scand J Rheumatol 2006 0.83
89 Interferon-alpha and interferon-gamma reduce excessive collagen synthesis and procollagen mRNA levels of scleroderma fibroblasts in culture. Biochim Biophys Acta 1988 0.83
90 Abnormal craniofacial growth and early mandibular osteoarthritis in mice harbouring a mutant type II collagen transgene. J Anat 1997 0.82
91 Collagen synthesis in the vaginal connective tissue of patients with and without uterine prolapse. Eur J Obstet Gynecol Reprod Biol 1987 0.81
92 Molecular biologic comparison of new bone formation and resorption on microrough and smooth bioactive glass microspheres. J Biomed Mater Res B Appl Biomater 2003 0.81
93 Expression of Sox9 and type IIA procollagen during ocular development and aging in transgenic Del1 mice with a mutation in the type II collagen gene. Eur J Ophthalmol 2003 0.81
94 Tissue distribution and phenotypic consequences of different type X collagen gene constructs in transgenic mice. Ann N Y Acad Sci 1996 0.81
95 The small dermatan sulphate proteoglycans synthesized by fibroblasts derived from skin, synovium and gingiva show tissue-related heterogeneity. Biochem J 1988 0.81
96 Localization of type II collagen mRNA isoforms in the developing eyes of normal and transgenic mice with a mutation in type II collagen gene. Invest Ophthalmol Vis Sci 1997 0.81
97 Bone defect repair in immobilization-induced osteopenia: a pQCT, biomechanical, and molecular biologic study in the mouse femur. Bone 2005 0.81
98 Silica-based bioactive glasses modulate expression of bone morphogenetic protein-2 mRNA in Saos-2 osteoblasts in vitro. Biomaterials 2001 0.80
99 The genes encoding alpha 2(IX) collagen (COL9A2) map to human chromosome 1p32.3-p33 and mouse chromosome 4. Genomics 1994 0.80
100 Comparison of the effects of dexamethasone and 13-cis-retinoic acid on connective tissue biosynthesis in human skin fibroblasts. Arch Dermatol Res 1989 0.80
101 Growth retardation in transgenic mice harboring a type II collagen mutation. Ann N Y Acad Sci 1996 0.79
102 Analysis of lapine cartilage matrix after radiosynovectomy with holmium-166 ferric hydroxide macroaggregate. Ann Rheum Dis 2003 0.79
103 Retarded skeletal development in transgenic mice with a type II collagen mutation. Am J Pathol 1996 0.79
104 The exon structure of the mouse alpha 2(IX) collagen gene shows unexpected divergence from the chick gene. J Biol Chem 1994 0.79
105 Exclusion of the COL2A1 gene as the mutation site in diastrophic dysplasia. J Med Genet 1989 0.79
106 Expression of type II and IX collagen isoforms during normal and pathological cartilage and eye development. Histochem Cell Biol 1998 0.79
107 Extended expression of cartilage components in experimental pseudoarthrosis. Connect Tissue Res 1995 0.79
108 Abnormal craniofacial development and expression patterns of extracellular matrix components in transgenic Del1 mice harboring a deletion mutation in the type II collagen gene. Orthod Craniofac Res 2004 0.79
109 Effects of cortisol on glycosaminoglycans synthesized by normal and rheumatoid synovial fibroblasts in vitro. Scand J Rheumatol 1977 0.79
110 Arthritis-associated changes in flow cytometric characteristics of cultured synovial fibroblasts. Arthritis Rheum 1988 0.79
111 Induction of periosteal callus formation by bone morphogenetic protein-2 employing adenovirus-mediated gene delivery. Matrix Biol 2001 0.79
112 Differences in connective tissue gene expression between normally functioning, polycystic and post-menopausal ovaries. Mol Hum Reprod 2004 0.79
113 Gene expression at graft-host interfaces of cortical bone allografts and autografts. Clin Orthop Relat Res 1993 0.78
114 Rheumatoid disease in cultured human synovial cells. A biochemical study on glycosaminoglycans, proteins and plasma membranes of synovial fibroblasts in culture. Scand J Clin Lab Invest Suppl 1977 0.78
115 Abnormalities in secondary cartilages in four lines of transgenic mice harboring two different types of mutations in the cartilage-specific type II collagen gene. J Craniofac Genet Dev Biol 1997 0.78
116 Distribution of glycosaminoglycans in rheumatoid cultures and effects of cortisol on it. Scand J Rheumatol 1980 0.78
117 Developmental regulation of mRNA species for types II, IX and XI collagens during mouse embryogenesis. Biochem J 1997 0.78
118 Physical mapping of mouse collagen genes on chromosome 10 by high-resolution FISH. Mamm Genome 2001 0.78
119 Expression of the c-Ha-ras and neu oncogenes in DMBA-induced, anti-estrogen-treated rat mammary tumors. Int J Cancer 1988 0.77
120 Mutation in type II collagen gene disturbs spinal development and gene expression patterns in transgenic Del1 mice. Lab Invest 1997 0.77
121 Retarded chondrogenesis in transgenic mice with a type II collagen defect results in fracture healing abnormalities. Dev Dyn 1994 0.77
122 Expression of type VI, IX and XI collagen genes and alternative splicing of type II collagen transcripts in fracture callus tissue in mice. FEBS Lett 1995 0.77
123 Expression of type I and III collagen and laminin beta1 after rat sciatic nerve crush injury. J Peripher Nerv Syst 1996 0.77
124 Expression of types I, III and IV collagen genes in fibrotic skin and nerve lesions of toxic oil syndrome patients. Clin Exp Immunol 1993 0.77
125 Effects of sodium aurothiomalate on hyaluronic acid synthesis in normal and rheumatoid synovial fibroblast cultures. Scand J Rheumatol 1979 0.77
126 Characterization of one phenotype of human periodontal granulation-tissue fibroblasts. J Dent Res 1989 0.77
127 Specific collagen mRNAs elucidate the histogenetic relationship between the growth plate, the tissue in the ossification groove of Ranvier, and the cambium layer of the adjacent periosteum. A preliminary report. Clin Orthop Relat Res 1993 0.77
128 Variability in the upstream promoter and intron sequences of the human, mouse and chick type X collagen genes. Matrix Biol 1996 0.76
129 Plasma membranes from experimental granulation tissue. Biochem J 1975 0.76
130 Altered distribution of type I collagen mRNA in periodontal disease. J Periodontal Res 1989 0.76
131 Adenovirus mediated intra-articular expression of collagenase-3 (MMP-13) induces inflammatory arthritis in mice. Ann Rheum Dis 2004 0.76
132 13-cis retinoic acid and dexamethasone modulate the gene expression of epidermal growth factor receptor and fibroblast proteoglycan 40 core protein in human skin fibroblasts. Acta Derm Venereol 1989 0.75
133 Towards genomic drug therapy with antisense oligonucleotides. Ann Med 1996 0.75
134 Transgenic mice with deficiencies in cartilage collagens: possible models for gene therapy. J Rheumatol Suppl 1995 0.75
135 Lack of DNA homology between arthritis triggering bacteria and plasmid of Yersinia enterocolitica or Chlamydia trachomatis. J Rheumatol 1986 0.75
136 Plasma membrane glycoproteins of cultured rheumatoid synovial fibroblasts. Clin Rheumatol 1983 0.75
137 Characterization of plasma membranes and rough endoplasmic reticulum of synovial cells cultured from rheumatoid arthritis patients. Scand J Rheumatol 1984 0.75
138 Expression and distribution of two alternatively spliced transcripts from the chicken alpha 2 (VI) collagen gene. J Cell Biochem 1996 0.75
139 Incorporation of cortical bone allografts and autografts in rats: expression patterns of mRNAs for the TGF-betas. Acta Orthop Scand 1998 0.75
140 [Research physician education has started]. Duodecim 1995 0.75
141 Gene therapy of single-gene disorders: preface to the special section. Ann Med 1997 0.75
142 Expression of proalpha1(I)- and proalpha1(III)collagen mRNA in chronic allograft rejection in a porcine heterotopic bronchial transplantation model. Transplant Proc 2001 0.75
143 [Misrepresenting the list of qualifications--a new form of scientific fraud?]. Duodecim 2000 0.75
144 Flow cytometry of fibroblasts cultured from skin of patients with localized scleroderma. Dermatologica 1988 0.75
145 Expression of matrix genes during incorporation of cancellous bone allografts and autografts. Clin Orthop Relat Res 1995 0.75
146 Abnormal mitochondria in cultured synovial fibroblasts in rheumatoid and reactive arthritis? Br J Rheumatol 1988 0.75
147 Expression of Sox9 and type IIA procollagen during ocular development and aging in transgenic Del1 mice with a mutation in the type II collagen gene. Eur J Ophthalmol 2017 0.75
148 Production of cartilage collagens during metaphyseal bone healing in the mouse. Matrix Biol 1998 0.75
149 Differential localization of type I and type III procollagen messenger ribonucleic acids in inflamed periodontal and periapical connective tissues by in situ hybridization. Lab Invest 1990 0.75
150 The effect of rheumatoid synovial fluid macrophages on DNA, glycosaminoglycan and collagen synthesis by synovial fibroblasts. Rheumatol Int 1983 0.75
151 [About the role of RNA]. Duodecim 1996 0.75
152 Different healing rates of bone autografts, syngeneic grafts, and allografts in an experimental rat model. Arch Orthop Trauma Surg 1997 0.75
153 Transgenic mice as models for heritable diseases. Ann Med 1992 0.75
154 Alterations in scleroderma fibroblast surface glycoproteins associated with increased collagen synthesis. Acta Derm Venereol 1987 0.75