| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
[Studies on beta-lactam antibiotics. III. Synthesis of 6-[D(--)-alpha-(acylamino)-phenylacetamido]penicillanic acids and antibacterial activity (author's transl)].
|
Yakugaku Zasshi
|
1980
|
0.91
|
|
2
|
Lack of significant estrogenic or antiestrogenic activity of pyrethroid insecticides in three in vitro assays based on classic estrogen receptor alpha-mediated mechanisms.
|
Toxicol Sci
|
2000
|
0.90
|
|
3
|
Dissection and weighing of accessory sex glands after formalin fixation, and a 5-day assay using young mature rats are reliable and feasible in the Hershberger assay.
|
Toxicology
|
2001
|
0.87
|
|
4
|
Evaluation of a 5-day Hershberger assay using young mature male rats: methyltestosterone and p,p'-DDE, but not fenitrothion, exhibited androgenic or antiandrogenic activity in vivo.
|
J Toxicol Sci
|
2000
|
0.82
|
|
5
|
Identification of a new non-functional CYP2C18 allele in Japanese: substitution of T204 to A in exon2 generates a premature stop codon.
|
Pharmacogenetics
|
1996
|
0.81
|
|
6
|
Radioiodinated 2'-iododiazepam: a potential imaging agent for SPECT investigations of benzodiazepine receptors.
|
J Nucl Med
|
1993
|
0.81
|
|
7
|
A new semi-automated chromosome analysis system for in vitro chromosomal aberration tests.
|
Mutat Res
|
1997
|
0.80
|
|
8
|
An in vitro reporter gene assay method incorporating metabolic activation with human and rat S9 or liver microsomes.
|
Biochem Biophys Res Commun
|
2001
|
0.79
|
|
9
|
An approach for assaying benzodiazepine receptor binding with radioiodinated ligand: 125I-labeled diazepam derivative.
|
Biol Pharm Bull
|
1993
|
0.79
|
|
10
|
Novel cleavage of the 1,2,4-oxadiazole ring in rat metabolism of SM-6586, a dihydropyridine calcium antagonist.
|
Drug Metab Dispos
|
1994
|
0.76
|
|
11
|
Metabolism of tetramethrin isomers in rat. I. Identification of a sulphonic acid type of conjugate and reduced metabolites.
|
Xenobiotica
|
1994
|
0.75
|
|
12
|
Alpha 2u-globulins in the urine of male rats: a reliable indicator for alpha 2u-globulin accumulation in the kidney.
|
Toxicology
|
1996
|
0.75
|
|
13
|
Preparation of tetramethylcyclopropanecarboxylic-14C acid and insecticidal terallethrin-14C from it.
|
Radioisotopes
|
1981
|
0.75
|
|
14
|
Development of a novel CHL/IU cell line with an incorporated gpt shuttle vector for concurrent analysis of gene mutations and chromosome aberrations.
|
Mutat Res
|
1997
|
0.75
|
|
15
|
Labelling of a new fungicide with 3H and 14C. Synthesis of S-n-butyl S'-p-tert-butylbenzyl N-3-pyridyl-(5-3H)-dithiocarbonimidate (Denmert).
|
Radioisotopes
|
1978
|
0.75
|
|
16
|
A method for measuring specific activities of 14C-labelled compounds by gas chromatography-mass spectrometry-computer system.
|
Radioisotopes
|
1985
|
0.75
|
|
17
|
Metabolism of Cyanox in rat. II. Sex-related differences in oxidative dearylation and desulphuration.
|
Xenobiotica
|
2000
|
0.75
|
|
18
|
Metabolism of N-[4-chloro-2-fluoro-5-[(1-methyl-2- propynl)oxy]phenyl]-3,4,5,6-tetrahydrophthalimide (S-23121) in the rat: I. Identification of a new, sulphonic acid type of conjugate.
|
Xenobiotica
|
1993
|
0.75
|
|
19
|
An improved method for 14C-labelling of farnesylacetic acid and its geranyl ester.
|
Radioisotopes
|
1988
|
0.75
|
|
20
|
[Usefulness of a disposable nasogastric tube with a pH sensor--comparison with a class pH electrode].
|
Masui
|
1992
|
0.75
|
|
21
|
11C-labeled 2'-iododiazepam for PET studies of benzodiazepine receptors: synthesis and comparison of biodistribution with its radioiodinated compound.
|
Ann Nucl Med
|
1994
|
0.75
|
|
22
|
Metabolism of tetramethrin isomers in rat: II. Identification and quantitation of metabolites.
|
Xenobiotica
|
1994
|
0.75
|
|
23
|
Radioiodinated 2'-iodospiperone: a new radioligand for in vivo dopamine receptor study.
|
Life Sci
|
1987
|
0.75
|
|
24
|
14C-labelling of a hypocholesterolemic agents, N-(alpha-methylbenzyl) linoleamide.
|
Radioisotopes
|
1980
|
0.75
|
|
25
|
Evaluation of N-alkyl derivatives of radioiodinated spiperone as radioligands for in vivo dopamine D2 receptor studies: effects of lipophilicity and receptor affinity on the in vivo biodistribution.
|
Chem Pharm Bull (Tokyo)
|
1992
|
0.75
|
|
26
|
Metabolism of furametpyr. 1. Identification of metabolites and in vitro biotransformation in rats and humans.
|
J Agric Food Chem
|
2000
|
0.75
|
|
27
|
Preparation of 123I-labeled 2'-iodospiperone and imaging of D2 dopamine receptors in the human brain using SPECT.
|
Int J Rad Appl Instrum B
|
1992
|
0.75
|
|
28
|
Differences in alpha 2u-globulins increased in male rat kidneys following treatment with several alpha 2u-globulin accumulating agents: cystein protease(s) play(s) an important role in production of kidney-type-alpha 2u-globulin.
|
Toxicology
|
1992
|
0.75
|
|
29
|
Quantitative determination of F6-1,25(OH)2 vitamin D3 in human serum by gas chromatography/mass spectrometry with high-resolution selected ion monitoring.
|
Biol Mass Spectrom
|
1994
|
0.75
|
|
30
|
Metabolism of a tetrahydroaminoacridine derivative (SM-10888) in rat: structural analysis of an N-glucuronide of SM-10888 and an O-glucuronide of hydroxylated SM-10888 by FAB-MS/MS.
|
Xenobiotica
|
1993
|
0.75
|
|
31
|
Application of gas chromatograph-mass spectrometer-computer system to evaluation of 14C-labelled compounds.
|
Radioisotopes
|
1985
|
0.75
|
|
32
|
Synthesis and evaluation of (17 alpha,20E)-21-[125I]iodo-19-norpregna-1,3,5(10),20-tetraene-3,17 -diol and (17 alpha,20E)-21-[125I]iodo-11 beta-methoxy-19-norpregna-1,3,5(10),20-tetraene-3,17-diol (17 alpha-(iodovinyl)estradiol derivatives) as high specific activity potential radiopharmaceuticals.
|
J Med Chem
|
1984
|
0.75
|
|
33
|
Metabolism of N-[4-chloro-2-fluoro-5-[(1-methyl-2-propynyl)oxy]phenyl]-3,4,5,6- tetrahydrophthalimide (S-23121) in the rat. II. Absorption, disposition, excretion and biotransformation.
|
Xenobiotica
|
1993
|
0.75
|
|
34
|
In vivo and in vitro pharmacokinetics and metabolism studies of 26,26,26,27,27,27-F6-1,25(OH)2 vitamin D3 (Falecalcitriol) in rat: induction of vitamin D3-24-hydroxylase (CYP24) responsible for 23S-hydroxylation in target tissues and the drop in serum levels.
|
Xenobiotica
|
1999
|
0.75
|
|
35
|
Radioiodinated nordiazepam analog for in vivo assessment of benzodiazepine receptors by single photon emission tomography.
|
Nucl Med Biol
|
1994
|
0.75
|
|
36
|
Metabolism of Cyanox in the rat. I. Absorption, disposition, excretion and biotransformation.
|
Xenobiotica
|
1995
|
0.75
|
|
37
|
Comparison of sex differences in guinea-pig maximization test for detection of skin-sensitizing potential using OECD recommended positive control sensitizers.
|
J Toxicol Sci
|
1998
|
0.75
|
|
38
|
Labelling of a new fungicide with 3H and 14C--synthesis of S-n-butyl S'-p-tert-butylbenzyl-14C N-3-Pyridyldithiocarbonimidate (Denmert).
|
Radioisotopes
|
1978
|
0.75
|
|
39
|
Evaluation of in vitro methods for detecting the effects of various chemicals on the human progesterone receptor, with a focus on pyrethroid insecticides.
|
Toxicol Lett
|
2001
|
0.75
|
|
40
|
14C-labelling of a new beta-adrenergic blocking agent (S-596).
|
Radioisotopes
|
1982
|
0.75
|
|
41
|
Pharmacokinetics of SM-10888 and its metabolites depending on their physicochemical properties.
|
Drug Metab Dispos
|
1994
|
0.75
|
|
42
|
Distribution and metabolism of F6-1,25(OH)2 vitamin D3 and 1,25(OH)2 vitamin D3 in the bones of rats dosed with tritium-labeled compounds.
|
Steroids
|
1998
|
0.75
|
|
43
|
14C-labelling of butylated hydroxytoluene (BHT).
|
Radioisotopes
|
1979
|
0.75
|
|
44
|
Metabolism of 4-[1-(2-fluoro-4-biphenylyl)ethyl]-2-methylaminothiazole (SM-8849) in rats.
|
Eur J Drug Metab Pharmacokinet
|
1997
|
0.75
|
|
45
|
Tissue distribution and pharmacological potential of SM-16896, a novel oestrogen-bisphosphonate hybrid compound.
|
J Pharm Pharmacol
|
2000
|
0.75
|
|
46
|
[The statistic study of morbus haradai. Clinical features in the initial stage and prognosis (author's transl)].
|
Nippon Ganka Gakkai Zasshi
|
1979
|
0.75
|
|
47
|
Benzodiazepines and their metabolites: relationship between binding affinity to the benzodiazepine receptor and pharmacological activity.
|
Life Sci
|
1985
|
0.75
|
|
48
|
Identification of two new types of S-linked conjugates of Etoc in rat.
|
Xenobiotica
|
1994
|
0.75
|
|
49
|
Synthesis of a 14C-labelled fungicide, N-(3, 5-dichlorophenyl)-1, 2-dimethylcyclopropane-1, 2-dicarboximide-(carbonyl-14C) (Sumilex).
|
Radioisotopes
|
1977
|
0.75
|
|
50
|
Metabolism of 7-fluoro-6-(3,4,5,6-tetrahydrophthalimido)-4- (2-propynyl)-2H-1,4-benzoxazin-3(4H)-one (S-53482) in rat. 1. Identification of a sulfonic acid type conjugate.
|
J Agric Food Chem
|
1999
|
0.75
|
|
51
|
[Effect of fenitrothion on experimental allergic conjunctivitis].
|
J Toxicol Sci
|
1996
|
0.75
|
|
52
|
Metabolism of tetramethrin isomers in rat. III. Stereochemistry of reduced metabolites.
|
Xenobiotica
|
1996
|
0.75
|
|
53
|
Metabolism of furametpyr. 2. (14)C excretion, (14)C concentrations in tissues, and amounts of metabolites in rats.
|
J Agric Food Chem
|
2000
|
0.75
|
|
54
|
Metabolism of 7-fluoro-6-(3,4,5,6-tetrahydrophthalimido)-4- (2-propynyl)-2H-1,4-benzoxazin-3(4H)-one (S-53482, flumioxazin) in the rat: II. Identification of reduced metabolites.
|
J Agric Food Chem
|
1999
|
0.75
|
|
55
|
Synthesis of 14C labelled o,o-dimethyl o-(3-carboxy-4-nitrophenyl) phosphorothioate.
|
Radioisotopes
|
1981
|
0.75
|
|
56
|
Metabolism of tetramethrin isomers in rat: IV. Tissues responsible for formation of reduced and hydrated metabolites.
|
Xenobiotica
|
1997
|
0.75
|