Published in Clin Pharmacol Ther on August 01, 1986
Chiral drugs: an overview. Int J Biomed Sci (2006) 1.31
Sedation and histamine H1-receptor antagonism: studies in man with the enantiomers of chlorpheniramine and dimethindene. Br J Pharmacol (1991) 0.97
Chirality and drugs used in psychiatry: nice to know or need to know? Cell Mol Neurobiol (1999) 0.92
Stereoselective peripheral sensory neurotoxicity of diaminocyclohexane platinum enantiomers related to ormaplatin and oxaliplatin. Br J Cancer (1997) 0.88
The pharmacokinetics of the enantiomers of flurbiprofen in patients with rheumatoid arthritis. Br J Clin Pharmacol (1991) 0.88
Stereoselective pharmacokinetics of oral and intravenous nitrendipine in healthy male subjects. Br J Clin Pharmacol (1991) 0.83
Use of pseudoracemic nitrendipine to elucidate the metabolic steps responsible for stereoselective disposition of nitrendipine enantiomers. Br J Clin Pharmacol (1992) 0.82
Clinical pharmacology through the looking glass: reflections on the racemate vs enantiomer debate. Br J Clin Pharmacol (1991) 0.81
Stereoselective drug disposition: potential for misinterpretation of drug disposition data. Br J Clin Pharmacol (1988) 0.80
Stereoselective central nervous system effects of the R- and S-isomers of the GABA uptake blocker N-(4, 4-di-(3-methylthien-2-yl)but-3-enyl) nipecotic acid in the rat. Br J Pharmacol (1999) 0.78
Neurochemical and metabolic aspects of antidepressants: an overview. J Psychiatry Neurosci (2000) 0.77
Mode of Action Studies on a Chiral Diphenyl Ether Peroxidizing Herbicide: Correlation between Differential Inhibition of Protoporphyrinogen IX Oxidase Activity and Induction of Tetrapyrrole Accumulation by the Enantiomers. Plant Physiol (1992) 0.75
Quantifying crystal form content in physical mixtures of (+/-)-tartaric acid and (+)-tartaric acid using near infrared reflectance spectroscopy. AAPS PharmSciTech (2005) 0.75
Chirality and anaesthetic drugs: A review and an update. Indian J Anaesth (2011) 0.75
Potential of alpha-amino alcohol p-boronophenylalaninol as a boron carrier in boron neutron capture therapy, regarding its enantiomers. J Cancer Res Clin Oncol (2003) 0.75
R-Modafinil exerts weak effects on spatial memory acquisition and dentate gyrus synaptic plasticity. PLoS One (2017) 0.75
Clinical consequences of polymorphic acetylation of basic drugs. Clin Pharmacol Ther (1977) 1.50
Effect of acetylator phenotype on the rate at which procainamide induces antinuclear antibodies and the lupus syndrome. N Engl J Med (1978) 1.37
Polymorphic acetylation procainamide in man. Clin Pharmacol Ther (1975) 1.32
Optimizing metoclopramide control of cisplatin-induced emesis. Ann Intern Med (1984) 1.30
Specific determination of quinidine and (3S)-3-hydroxyquinidine in human serum by high-pressure liquid chromatography. J Lab Clin Med (1977) 1.13
Steady-state serum levels of quinidine and active metabolites in cardiac patients with varying degrees of renal function. Clin Pharmacol Ther (1978) 1.13
Increased urinary enzyme excretion in workers exposed to nephrotoxic chemicals. Am J Med (1984) 1.12
Aging and renal clearance of procainamide and acetylprocainamide. Clin Pharmacol Ther (1980) 1.01
Alteration of drug-protein binding in renal disease. Clin Pharmacokinet (1984) 0.99
In vitro acetylation of drugs by human blood cells. Drug Metab Dispos (1975) 0.95
Stereoselective renal tubular secretion of quinidine and quinine. Clin Pharmacol Ther (1986) 0.94
Antibodies to nuclear antigens in patients treated with procainamide or acetylprocainamide. N Engl J Med (1979) 0.94
Increased excretion of urinary N-acetyl-beta-glucosaminidase in essential hypertension and its decline with antihypertensive therapy. N Engl J Med (1983) 0.92
N-acetyl-beta-glucosaminidase and beta 2-microglobulin. Their urinary excretion in patients with renal parenchymal disease. Arch Intern Med (1983) 0.90
Development of antinuclear antibody in patients treated with high doses of captopril. Arthritis Rheum (1984) 0.88
Pharmacologically active drug metabolites: therapeutic and toxic activities, plasma and urine data in man, accumulation in renal failure. Clin Pharmacokinet (1977) 0.87
Aromatic amines and hydrazines drug acetylation, and lupus erythematodes. Hum Genet Suppl (1978) 0.86
Pubertal changes in net renal tubular secretion of digoxin. Clin Pharmacol Ther (1984) 0.86
N-acetylprocainamide: an active metabolite of procainamide. Proc Soc Exp Biol Med (1974) 0.86
Acetylation phenotypes and environmental chemical exposure of people with idiopathic systemic lupus erythematosus. Arthritis Rheum (1993) 0.86
Effects of renal disease upon drug disposition. Drug Metab Rev (1978) 0.86
Pharmacologically active metabolites of drugs and other foreign compounds. Clinical, pharmacological, therapeutic and toxicological considerations. Drugs (1982) 0.85
Acetylator phenotype in idiopathic systemic lupus erythematosus. Arthritis Rheum (1980) 0.84
Age and renal clearance of cimetidine. Clin Pharmacol Ther (1982) 0.82
Plasma levels, protein binding, and elimination data of lidocaine and active metabolites in cardiac patients of various ages. Clin Pharmacol Ther (1983) 0.82
Drug therapy in renal failure. Annu Rev Pharmacol Toxicol (1980) 0.82
Improved method for the measurement of cimetidine in human serum by reverse-phase high-pressure liquid chromatography. J Lab Clin Med (1981) 0.82
Cumulation of N-acetylprocainamide, an active metabolite of procainamide, in patients with impaired renal function. Clin Pharmacol Ther (1977) 0.80
Acetylprocainamide therapy in patients with previous procainamide-induced lupus syndrome. Ann Intern Med (1981) 0.79
Correlation of the electrophysiological and antiarrhythmic properties of the N-acetyl metabolite of procainamide with plasma and tissue drug concentrations in the dog. J Pharmacol Exp Ther (1976) 0.79
Hydromorphone levels and pain control in patients with severe chronic pain. Clin Pharmacol Ther (1988) 0.79
Microsomal hydroxylation as measured by pentobarbital elimination in patients with idiopathic systemic lupus erythematosus. Clin Pharmacol Ther (1982) 0.78
Propylthiouracil-induced immune-mediated disease in the cat. J Pharmacol Exp Ther (1985) 0.77
Dose-dependent induction of anti-native DNA antibodies in cats by propylthiouracil. Arthritis Rheum (1988) 0.77
Alterations in state in apneic pre-term infants receiving theophylline. Clin Pharmacol Ther (1978) 0.77
Procainamide, N-acetylprocainamide, antinuclear antibody and systemic lupus erythematosus. Angiology (1986) 0.77
Pharmacokinetics of pentobarbital enantiomers as determined by enantioselective radioimmunoassay after administration of racemate to humans and rabbits. J Pharmacol Exp Ther (1987) 0.77
Simultaneous determination of dipyrone metabolites in plasma by high-performance liquid chromatography. J Chromatogr (1984) 0.76
A nonradioactive iothalamate method for measuring glomerular filtration rate and its use to study the renal handling of cibenzoline. Ther Drug Monit (1988) 0.76
Determination of gossypol enantiomers in plasma after administration of racemate using high-performance liquid chromatography with precolumn chemical derivatisation. J Chromatogr (1988) 0.75
Drug metabolism and active drug metabolites in renal failure. J Dial (1977) 0.75
Prevalence of high (3S)-3-hydroxyquinidine/quinidine ratios in serum, and clearance of quinidine in cardiac patients with age. Clin Pharmacol Ther (1980) 0.75
Renal injury in patients with rheumatoid arthritis treated with gold. Clin Pharmacol Ther (1980) 0.75
Pathways of drug metabolism in man. Med Clin North Am (1974) 0.75
Accumulation of polyamines and their weak association with lower body temperature in elderly convalescent patients. J Lab Clin Med (1987) 0.75
Comparison of antiarrhythmic effects of procainamide, N-acetylprocainamide, and p-hydroxy-N-(3-diethylaminopropyl)benzamide. Proc Soc Exp Biol Med (1982) 0.75
Metoclopramide and chemotherapy-induced emesis. Ann Intern Med (1984) 0.75
Cross reactivity of the EMIT digoxin assay with digoxin metabolites, and validation of the method for measurement of urinary digoxin. Clin Chem (1983) 0.75
Liquid chromatography and fluorescence spectroscopy compared with a homogeneous enzyme immunoassay technique for determining quinidine in serum. Clin Chem (1981) 0.75
Active drug metabolites and renal failure. Am J Med (1977) 0.75
Long-term antiarrhythmic therapy with acetylprocainamide. Am J Cardiol (1981) 0.75
Antibodies: a rich source of novel chemical agents for pharmacological studies. Trends Pharmacol Sci (1988) 0.75
Antiarrhythmic activity of p-hydroxy-N-(2-diethylaminoethyl) benzamide (the p-hydroxy isostere of procainamide) in dogs and mice. J Med Chem (1977) 0.75
Metabolism of tetralin and toxicity of Cuprex in man. Drug Metab Dispos (1974) 0.75
Clinical consequences of the lipophilicity and plasma protein binding of antiarrhythmic drugs and active metabolites in man. Ann N Y Acad Sci (1984) 0.75
Unusual cause of theophylline toxicity. N Y State J Med (1979) 0.75