Published in J Math Biol on June 12, 1978
Diffusion with attrition. J Math Biol (2006) 0.87
Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature (1995) 34.97
Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques. J Exp Med (1999) 14.30
Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy. Science (1998) 10.43
Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy. N Engl J Med (1999) 7.07
Persistence of HIV-1 transcription in peripheral-blood mononuclear cells in patients receiving potent antiretroviral therapy. N Engl J Med (1999) 5.18
Model for chemotaxis. J Theor Biol (1971) 5.01
Quantitative image analysis of HIV-1 infection in lymphoid tissue. Science (1996) 4.72
Rapid production and clearance of HIV-1 and hepatitis C virus assessed by large volume plasma apheresis. Lancet (1999) 4.36
The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy. Nat Med (2000) 4.08
Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study. Proc Natl Acad Sci U S A (2000) 3.74
Modeling plasma virus concentration during primary HIV infection. J Theor Biol (2000) 3.40
Rapid turnover of T lymphocytes in SIV-infected rhesus macaques. Science (1998) 3.39
Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy. J Exp Med (2001) 3.37
Variable efficacy of repeated annual influenza vaccination. Proc Natl Acad Sci U S A (1999) 3.35
Turnover of CD4+ and CD8+ T lymphocytes in HIV-1 infection as measured by Ki-67 antigen. J Exp Med (1998) 3.24
Initiation of slime mold aggregation viewed as an instability. J Theor Biol (1970) 3.14
Traveling bands of chemotactic bacteria: a theoretical analysis. J Theor Biol (1971) 2.67
Nonlinear dynamics of immunogenic tumors: parameter estimation and global bifurcation analysis. Bull Math Biol (1994) 2.65
Human immunodeficiency virus fitness in vivo: calculations based on a single zidovudine resistance mutation at codon 215 of reverse transcriptase. J Virol (1996) 2.61
Theoretical studies of clonal selection: minimal antibody repertoire size and reliability of self-non-self discrimination. J Theor Biol (1979) 2.58
Evolution of envelope sequences of human immunodeficiency virus type 1 in cellular reservoirs in the setting of potent antiviral therapy. J Virol (1999) 2.42
Dissipative structure: an explanation and an ecological example. J Theor Biol (1972) 2.27
Dose-dependent acute clearance of hepatitis C genotype 1 virus with interferon alfa. Hepatology (1997) 2.23
Rate of HIV-1 decline following antiretroviral therapy is related to viral load at baseline and drug regimen. AIDS (1998) 2.19
The physics of cell motility. J Cell Sci Suppl (1987) 2.13
Effects of in vivo CD8(+) T cell depletion on virus replication in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine. J Exp Med (2000) 2.10
Mathematical and computational challenges in population biology and ecosystems science. Science (1997) 2.01
Drug concentration heterogeneity facilitates the evolution of drug resistance. Proc Natl Acad Sci U S A (1998) 1.95
Emergence of drug resistance during an influenza epidemic: insights from a mathematical model. J Infect Dis (1998) 1.85
Network thermodynamics: dynamic modelling of biophysical systems. Q Rev Biophys (1973) 1.81
Cyclic re-entry of germinal center B cells and the efficiency of affinity maturation. Immunol Today (1993) 1.78
Target cell limited and immune control models of HIV infection: a comparison. J Theor Biol (1998) 1.77
Differences in viral dynamics between genotypes 1 and 2 of hepatitis C virus. J Infect Dis (2000) 1.76
Recruitment times, proliferation, and apoptosis rates during the CD8(+) T-cell response to lymphocytic choriomeningitis virus. J Virol (2001) 1.72
Size and connectivity as emergent properties of a developing immune network. J Theor Biol (1991) 1.69
On the validity of the steady state assumption of enzyme kinetics. Bull Math Biol (1988) 1.67
A perspective on modelling hepatitis C virus infection. J Viral Hepat (2010) 1.67
Quantification of cell turnover kinetics using 5-bromo-2'-deoxyuridine. J Immunol (2000) 1.67
Analysis of hepatitis B viral load decline under potent therapy: complex decay profiles observed. Hepatology (2001) 1.65
Extending the quasi-steady state approximation by changing variables. Bull Math Biol (1996) 1.61
Influence of delayed viral production on viral dynamics in HIV-1 infected patients. Math Biosci (1998) 1.60
A molecular mechanism for sensory adaptation based on ligand-induced receptor modification. Proc Natl Acad Sci U S A (1986) 1.56
A mechanism for exact sensory adaptation based on receptor modification. J Theor Biol (1986) 1.54
Persistence of infectious HIV on follicular dendritic cells. J Immunol (2001) 1.54
Rapid clearance of simian immunodeficiency virus particles from plasma of rhesus macaques. J Virol (1999) 1.52
Localized or systemic in vivo heat inactivation of human immunodeficiency virus (HIV): a mathematical analysis. J Acquir Immune Defic Syndr Hum Retrovirol (1995) 1.50
Protein evolution on rugged landscapes. Proc Natl Acad Sci U S A (1989) 1.37
Steric effects on multivalent ligand-receptor binding: exclusion of ligand sites by bound cell surface receptors. Biophys J (1999) 1.33
T cell repertoires and competitive exclusion. J Theor Biol (1994) 1.32
Somatic mutation leads to efficient affinity maturation when centrocytes recycle back to centroblasts. J Immunol (1997) 1.31
Deriving shape space parameters from immunological data. J Theor Biol (1997) 1.29
The metabolism, pharmacokinetics and mechanisms of antiviral activity of ribavirin against hepatitis C virus. Cell Mol Life Sci (2006) 1.28
Dissociation of HIV-1 from follicular dendritic cells during HAART: mathematical analysis. Proc Natl Acad Sci U S A (1999) 1.27
Kinetics of acute hepatitis B virus infection in humans. J Exp Med (2001) 1.26
Optimal strategies in immunology III. The IgM-IgG switch. J Math Biol (1980) 1.24
A model of HIV-1 pathogenesis that includes an intracellular delay. Math Biosci (2000) 1.23
Vesicle formation in the Golgi apparatus. J Theor Biol (1989) 1.22
How diverse should the immune system be? Proc Biol Sci (1993) 1.22
Equilibrium theory for the clustering of bivalent cell surface receptors by trivalent ligands. Application to histamine release from basophils. Biophys J (1984) 1.21
Influence of follicular dendritic cells on decay of HIV during antiretroviral therapy. Proc Natl Acad Sci U S A (2000) 1.20
Mathematical models for the evolution of multigene families by unequal crossing over. Nature (1977) 1.20
Improved estimates for HIV-1 clearance rate and intracellular delay. AIDS (1999) 1.17
Mathematical analysis of antiretroviral therapy aimed at HIV-1 eradication or maintenance of low viral loads. J Theor Biol (1998) 1.17
Theoretical analysis of chemotactic movement in bacteria. J Mechanochem Cell Motil (1973) 1.15
Somatic hypermutation in B cells: an optimal control treatment. J Theor Biol (1993) 1.14
A simple quantitative assay for bacterial motility. J Gen Microbiol (1977) 1.12
Unified mechanism for relay and oscillation of cyclic AMP in Dictyostelium discoideum. Proc Natl Acad Sci U S A (1977) 1.10
Towards a general function describing T cell proliferation. J Theor Biol (1995) 1.10
Modelling hepatitis C virus kinetics during treatment with pegylated interferon alpha-2b: errors in the estimation of viral kinetic parameters. J Viral Hepat (2008) 1.06
A theoretical study of calcium entry in nerve terminals, with application to neurotransmitter release. J Theor Biol (1981) 1.04
Standing-gradient flows driven by active solute transport. J Theor Biol (1970) 1.04
A theoretical explanation for some effects of calcium on the facilitation of neurotransmitter release. J Theor Biol (1980) 1.04
Analysis of countercurrent diffusion exchange in blood vessels of the renal medulla. Am J Physiol (1971) 1.03
A numerical study of the formation and propagation of traveling bands of chemotactic bacteria. J Theor Biol (1974) 1.03
The paucity of plants evolving genetic resistance to herbicides: possible reasons and implications. J Theor Biol (1978) 1.02
Modeling and optimization of populations subject to time-dependent mutation. Proc Natl Acad Sci U S A (1995) 1.02
Control of developmental transitions in the cyclic AMP signalling system of Dictyostelium discoideum. Differentiation (1980) 1.00
Th1 or Th2: how an appropriate T helper response can be made. Bull Math Biol (2001) 0.98
Modeling HIV infection of CD4+ T-cell subpopulations. J Theor Biol (1994) 0.98
Quantitative model of ColE1 plasmid copy number control. J Mol Biol (1993) 0.98
Spatial distribution of surface immunoglobulin on B lymphocytes. Local ordering. Exp Cell Res (1978) 0.98
Equilibrium binding of multivalent ligands to cells: effects of cell and receptor density. Math Biosci (1996) 0.98
Optimal strategies in immunology. I. B-cell differentiation and proliferation. J Math Biol (1976) 0.96
Mechanism of cell-mediated cytotoxicity at the single cell level. VIII. Kinetics of lysis of target cells bound by more than one cytotoxic T lymphocyte. J Immunol (1984) 0.96
Kinetics of rouleau formation. I. A mass action approach with geometric features. Biophys J (1982) 0.96
Cell migrations during morphogenesis: some clues from the slug of Dictyostelium discoideum. Bioessays (1986) 0.96
A basic biophysical model for bursting neurons. Biol Cybern (1993) 0.96
Predicting the size of the T-cell receptor and antibody combining region from consideration of efficient self-nonself discrimination. Proc Natl Acad Sci U S A (1993) 0.96
Estimation of early hepatitis C viral clearance in patients receiving daily interferon and ribavirin therapy using a mathematical model. Hepatology (2001) 0.95
Modeling defective interfering virus therapy for AIDS: conditions for DIV survival. Math Biosci (1995) 0.94
Quantifying aggregation of IgE-FcepsilonRI by multivalent antigen. Biophys J (1999) 0.93
Effect of drug efficacy and the eclipse phase of the viral life cycle on estimates of HIV viral dynamic parameters. J Acquir Immune Defic Syndr (2001) 0.93
Delivery of lethal hits by cytotoxic T lymphocytes in multicellular conjugates occurs sequentially but at random times. J Immunol (1982) 0.92
G-CSF control of neutrophils dynamics in the blood. Bull Math Biol (2007) 0.91
Explaining high alloreactivity as a quantitative consequence of affinity-driven thymocyte selection. Proc Natl Acad Sci U S A (1999) 0.91
Role of the thymus in pediatric HIV-1 infection. J Acquir Immune Defic Syndr Hum Retrovirol (1998) 0.90
A multistage model for the action of cytotoxic T lymphocytes in multicellular conjugates. J Immunol (1984) 0.90
Modeling adaptive biological systems. Biosystems (1989) 0.89
Th1/Th2 cross regulation. J Theor Biol (1994) 0.89
Competitive control of the self-renewing T cell repertoire. Int Immunol (1997) 0.89