| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Transdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men.
|
J Clin Endocrinol Metab
|
2000
|
2.68
|
|
2
|
Hormonal and genetic control of germ cell apoptosis in the testis.
|
Rev Reprod
|
1999
|
1.65
|
|
3
|
Testosterone replacement therapy improves mood in hypogonadal men--a clinical research center study.
|
J Clin Endocrinol Metab
|
1996
|
1.57
|
|
4
|
A controlled comparison of the efficacy of clomiphene citrate in male infertility.
|
Fertil Steril
|
1988
|
1.50
|
|
5
|
Single exposure to heat induces stage-specific germ cell apoptosis in rats: role of intratesticular testosterone on stage specificity.
|
Endocrinology
|
1999
|
1.47
|
|
6
|
Testicular pathologic changes and the pituitary-testicular axis during human immunodeficiency virus infection.
|
Endocr Pract
|
2004
|
1.40
|
|
7
|
The Prader-Willi syndrome: a study of 40 patients and a review of the literature.
|
Medicine (Baltimore)
|
1983
|
1.39
|
|
8
|
Simultaneous radioimmunoassay of plasma FSH, LH, progesterone, 17-hydroxyprogesterone, and estradiol-17 beta during the menstrual cycle.
|
J Clin Endocrinol Metab
|
1972
|
1.29
|
|
9
|
Reproductive hormonal function in the genetically obese (ob/ob) mouse.
|
Endocrinology
|
1976
|
1.28
|
|
10
|
Low serum testosterone and sex-hormone-binding-globulin in massively obese men.
|
J Clin Endocrinol Metab
|
1977
|
1.26
|
|
11
|
Male sexual function and its disorders: physiology, pathophysiology, clinical investigation, and treatment.
|
Endocr Rev
|
2001
|
1.25
|
|
12
|
Pharmacokinetics of transdermal testosterone gel in hypogonadal men: application of gel at one site versus four sites: a General Clinical Research Center Study.
|
J Clin Endocrinol Metab
|
2000
|
1.21
|
|
13
|
Sublingual testosterone replacement improves muscle mass and strength, decreases bone resorption, and increases bone formation markers in hypogonadal men--a clinical research center study.
|
J Clin Endocrinol Metab
|
1996
|
1.17
|
|
14
|
Serum luteinizing and follicle stimulating hormone levels during sequential and nonsequential contraceptive treatment of eugonadal women.
|
J Clin Endocrinol Metab
|
1969
|
1.17
|
|
15
|
Involvement of apoptosis in the induction of germ cell degeneration in adult rats after gonadotropin-releasing hormone antagonist treatment.
|
Endocrinology
|
1995
|
1.17
|
|
16
|
Nutritional and metabolic effects of gonadotropin-releasing hormone agonist treatment for prostate cancer.
|
Metabolism
|
1990
|
1.13
|
|
17
|
Neurobehavioral phenotype of Klinefelter syndrome.
|
Ment Retard Dev Disabil Res Rev
|
2000
|
1.11
|
|
18
|
Significance of apoptosis in the temporal and stage-specific loss of germ cells in the adult rat after gonadotropin deprivation.
|
Biol Reprod
|
1997
|
1.10
|
|
19
|
Androgen-behavior correlations in hypogonadal men and eugonadal men. II. Cognitive abilities.
|
Horm Behav
|
1998
|
1.07
|
|
20
|
Testicular heat exposure enhances the suppression of spermatogenesis by testosterone in rats: the "two-hit" approach to male contraceptive development.
|
Endocrinology
|
2000
|
1.07
|
|
21
|
Hormonal therapy of cryptorchidism. A randomized, double-blind study comparing human chorionic gonadotropin and gonadotropin-releasing hormone.
|
N Engl J Med
|
1986
|
1.07
|
|
22
|
Progestogen-induced luteinizing and follicle-stimulating hormone surge in postmenopausal women: a simulated ovulatory peak.
|
Proc Natl Acad Sci U S A
|
1968
|
1.06
|
|
23
|
Effects of transdermal testosterone gel on bone turnover markers and bone mineral density in hypogonadal men.
|
Clin Endocrinol (Oxf)
|
2001
|
1.04
|
|
24
|
The structural brain correlates of cognitive deficits in adults with Klinefelter's syndrome.
|
J Clin Endocrinol Metab
|
2006
|
1.03
|
|
25
|
Role of temperature in regulation of spermatogenesis and the use of heating as a method for contraception.
|
Fertil Steril
|
1988
|
1.01
|
|
26
|
Neuropsychological profiles of adults with Klinefelter syndrome.
|
J Int Neuropsychol Soc
|
2001
|
1.01
|
|
27
|
Mechanisms of gonadotropin-releasing hormone agonist action in the human male.
|
Endocr Rev
|
1986
|
1.00
|
|
28
|
Obesity, low testosterone levels and erectile dysfunction.
|
Int J Impot Res
|
2008
|
0.99
|
|
29
|
Long-term effects of triptolide on spermatogenesis, epididymal sperm function, and fertility in male rats.
|
J Androl
|
2000
|
0.98
|
|
30
|
Ethnic differences in testicular structure and spermatogenic potential may predispose testes of Asian men to a heightened sensitivity to steroidal contraceptives.
|
J Androl
|
1998
|
0.97
|
|
31
|
Influence of immunization procedures on the titer, affinity and specificity of antisera to glycopolypeptides.
|
Acta Endocrinol Suppl (Copenh)
|
1969
|
0.97
|
|
32
|
Androgens: risks and benefits.
|
J Clin Endocrinol Metab
|
1991
|
0.96
|
|
33
|
In vitro inhibition of testosterone biosynthesis by ketoconazole.
|
Endocrinology
|
1985
|
0.94
|
|
34
|
Serum LH and FSH during sexual maturation in the male rat: effect of castration and cryptorchidism.
|
Endocrinology
|
1971
|
0.93
|
|
35
|
Temporal and stage-specific changes in spermatogenesis of rat after gonadotropin deprivation by a potent gonadotropin-releasing hormone antagonist treatment.
|
Endocrinology
|
1993
|
0.92
|
|
36
|
Comparison of the kinetics of injectable testosterone in eugonadal and hypogonadal men.
|
Fertil Steril
|
1982
|
0.92
|
|
37
|
Etiologies of sexual maturation: a model system based on the sexually maturing rat.
|
Recent Prog Horm Res
|
1976
|
0.91
|
|
38
|
DDT homologues: estrogen-like effects on the vagina, uterus and pituitary of the rat.
|
Endocrinology
|
1972
|
0.91
|
|
39
|
Male contraception; synergism of gonadotropin-releasing hormone analog and testosterone in suppressing gonadotropin.
|
Science
|
1980
|
0.90
|
|
40
|
FSH induction of sensitivity to LH: one cause of sexual maturation in the male rat.
|
Endocrinology
|
1973
|
0.90
|
|
41
|
Lead toxicity and the hypothalamic-pituitary-testicular axis.
|
Biol Reprod
|
1985
|
0.89
|
|
42
|
Levonorgestrel implants (Norplant II) for male contraception clinical trials: combination with transdermal and injectable testosterone.
|
J Clin Endocrinol Metab
|
2002
|
0.89
|
|
43
|
The effect of sexual maturation on testicular response to LH stimulation of testosterone secretion in the intact rat.
|
Endocrinology
|
1974
|
0.89
|
|
44
|
Posttesticular antifertility action of triptolide in the male rat: evidence for severe impairment of cauda epididymal sperm ultrastructure.
|
J Androl
|
2000
|
0.89
|
|
45
|
Sexual function does not change when serum testosterone levels are pharmacologically varied within the normal male range.
|
Fertil Steril
|
1993
|
0.88
|
|
46
|
Spontaneous expression of inducible nitric oxide synthase in the hypothalamus and other brain regions of aging rats.
|
Endocrinology
|
1998
|
0.88
|
|
47
|
Triptolide: a potential male contraceptive.
|
J Androl
|
1998
|
0.88
|
|
48
|
Comparative pharmacokinetics of three doses of percutaneous dihydrotestosterone gel in healthy elderly men--a clinical research center study.
|
J Clin Endocrinol Metab
|
1998
|
0.88
|
|
49
|
Redistribution of Bax is an early step in an apoptotic pathway leading to germ cell death in rats, triggered by mild testicular hyperthermia.
|
Biol Reprod
|
2000
|
0.88
|
|
50
|
Spontaneous germ cell apoptosis in humans: evidence for ethnic differences in the susceptibility of germ cells to programmed cell death.
|
J Clin Endocrinol Metab
|
1998
|
0.87
|
|
51
|
XXY male mice: an experimental model for Klinefelter syndrome.
|
Endocrinology
|
2001
|
0.87
|
|
52
|
Up-regulation of the levels of androgen receptor and its mRNA by androgens in smooth-muscle cells from rat penis.
|
Mol Cell Endocrinol
|
1993
|
0.87
|
|
53
|
Aging results in attenuated gonadotropin releasing hormone-luteinizing hormone axis responsiveness to glutamate receptor agonist N-methyl-D-aspartate.
|
J Neuroendocrinol
|
1998
|
0.87
|
|
54
|
Hormonal mechanisms in the onset of puberty.
|
Postgrad Med J
|
1975
|
0.86
|
|
55
|
Testosterone down-regulates the levels of androgen receptor mRNA in smooth muscle cells from the rat corpora cavernosa via aromatization to estrogens.
|
J Steroid Biochem Mol Biol
|
1993
|
0.86
|
|
56
|
Aging-related increased expression of inducible nitric oxide synthase and cytotoxicity markers in rat hypothalamic regions associated with male reproductive function.
|
Neuroendocrinology
|
2001
|
0.86
|
|
57
|
Reproductive aging in the Brown Norway rat is characterized by accelerated germ cell apoptosis and is not altered by luteinizing hormone replacement.
|
J Androl
|
1999
|
0.86
|
|
58
|
Beta-adrenergic receptor and cyclic AMP alterations in the canine ventricular septum during long-term norepinephrine infusion: implications for hypertrophic cardiomyopathy.
|
Circulation
|
1983
|
0.85
|
|
59
|
Pituitary and gonadal hormones in patients with varicocele.
|
Fertil Steril
|
1975
|
0.85
|
|
60
|
Thyroid hormone modulation of thyrotrophin-releasing hormone (TRH) and TRH-Gly levels in the male rat reproductive system.
|
J Endocrinol
|
1987
|
0.85
|
|
61
|
Effect of in vitro ketoconazole on steroid production in rat testis.
|
Steroids
|
1986
|
0.85
|
|
62
|
Endocrine effects of acute and chronic cimetidine administration.
|
Dig Dis Sci
|
1981
|
0.84
|
|
63
|
Radioimmunoassay of plasma 17-hydroxyprogesterone.
|
J Clin Endocrinol Metab
|
1971
|
0.84
|
|
64
|
Effect of testosterone enanthate on hematopoiesis in normal men.
|
Fertil Steril
|
1983
|
0.84
|
|
65
|
Influence of age on the intravenous tolbutamide response test.
|
Diabetes
|
1967
|
0.83
|
|
66
|
Physiological control of puberty.
|
Med Clin North Am
|
1978
|
0.83
|
|
67
|
Biphasic effect of testosterone on spermatogenesis in the rat.
|
Invest Urol
|
1973
|
0.83
|
|
68
|
Identification and partial characterization of gonadotropin-releasing hormone-like factors in human seminal plasma.
|
Biol Reprod
|
1985
|
0.83
|
|
69
|
Testosterone replacement ameliorates nonalcoholic fatty liver disease in castrated male rats.
|
Endocrinology
|
2013
|
0.83
|
|
70
|
UCLA conference. Infertility in the male.
|
Ann Intern Med
|
1985
|
0.83
|
|
71
|
Serum triiodothyronine in undernourished rats: dependence on dietary composition rather than total calorie or protein intake.
|
Endocrinology
|
1978
|
0.83
|
|
72
|
The hypothalamic-pituitary axis in genetically obese (ob/ob) mice: response to luteinizing hormone-releasing hormone.
|
Endocrinology
|
1978
|
0.82
|
|
73
|
Androgen-behavior correlations in hypogonadal men and eugonadal men. I. Mood and response to auditory sexual stimuli.
|
Horm Behav
|
1997
|
0.82
|
|
74
|
In the male brown-Norway (BN) male rat, reproductive aging is associated with decreased LH-pulse amplitude and area.
|
J Androl
|
1997
|
0.82
|
|
75
|
A psychiatric study of patients referred with a diagnosis of hypoglycemia.
|
Am J Psychiatry
|
1976
|
0.82
|
|
76
|
Effects of aging on the in vitro release of gonadotropin-releasing hormone.
|
Endocrinology
|
1986
|
0.82
|
|
77
|
Developments in the control of testicular function.
|
Baillieres Clin Endocrinol Metab
|
1992
|
0.81
|
|
78
|
Temporal and stage-specific effects of recombinant human follicle-stimulating hormone on the maintenance of spermatogenesis in gonadotropin-releasing hormone antagonist-treated rat.
|
Endocrinology
|
1995
|
0.81
|
|
79
|
Time course of recovery of spermatogenesis and Leydig cell function after cessation of gonadotropin-releasing hormone antagonist treatment in the adult rat.
|
Endocrinology
|
1994
|
0.81
|
|
80
|
Search for a substance which selectively inhibits FSH--effects of steroids and prostaglandins on serum FSH and LH levels.
|
Steroids
|
1973
|
0.81
|
|
81
|
Gonadotropin therapy failure secondary to human chorionic gonadotropin-induced antibodies.
|
J Clin Endocrinol Metab
|
1981
|
0.81
|
|
82
|
Effect of increased scrotal temperature on sperm production in normal men.
|
Fertil Steril
|
1997
|
0.81
|
|
83
|
Effect of estradiol on uterine weight, thyroid function food intake, and pituitary weight of genetically obese (fatty-Zucker) and lean rats.
|
Proc Soc Exp Biol Med
|
1976
|
0.81
|
|
84
|
Hormonal effects of ketoconazole in vivo in the male rat: mechanism of action.
|
Endocrinology
|
1986
|
0.81
|
|
85
|
Cyproterone: effect on serum gonadotropins in the male.
|
Endocrinology
|
1972
|
0.80
|
|
86
|
Impairment of spermatogenesis in transgenic mice with selective overexpression of Bcl-2 in the somatic cells of the testis.
|
J Androl
|
2001
|
0.80
|
|
87
|
Dissociating antifertility effects of GnRH-antagonist from its adverse effects on mating behavior in male rats.
|
Am J Physiol
|
1988
|
0.80
|
|
88
|
Graded testosterone infusions distinguish gonadotropin negative-feedback responsiveness in Asian and white men--a Clinical Research Center study.
|
J Clin Endocrinol Metab
|
1998
|
0.80
|
|
89
|
The role of hypothalamic adrenergic receptors in preventing testosterone-induced androgenization in the female rat brain.
|
Endocrinology
|
1981
|
0.80
|
|
90
|
Nuclear accumulation of estradiol derived from the aromatization of testosterone is inhibited by hypothalamic beta-receptor stimulation in the neonatal female rat.
|
Biol Reprod
|
1984
|
0.80
|
|
91
|
Effects of cyclosporine on the hypothalamic-pituitary-gonadal axis in the male rat: mechanism of action.
|
Endocrinology
|
1988
|
0.79
|
|
92
|
A biodegradable testosterone microcapsule formulation provides uniform eugonadal levels of testosterone for 10-11 weeks in hypogonadal men.
|
J Clin Endocrinol Metab
|
1992
|
0.79
|
|
93
|
Reproductive function in the genetically obese "fatty" rat.
|
Endocrinology
|
1973
|
0.79
|
|
94
|
Screening urine for exogenous testosterone by isotope ratio mass spectrometric analysis of one pregnanediol and two androstanediols.
|
J Chromatogr B Biomed Sci Appl
|
1999
|
0.79
|
|
95
|
Androgen replacement therapy.
|
Curr Ther Endocrinol Metab
|
1997
|
0.79
|
|
96
|
Superactive gonadotropin-releasing hormone agonists.
|
Annu Rev Med
|
1983
|
0.79
|
|
97
|
Early effects of vasectomy on testicular structure and on germ cell and macrophage apoptosis in the hamster.
|
J Androl
|
1997
|
0.78
|
|
98
|
NIH conference. Therapeutic applications of luteinizing-hormone-releasing hormone and its analogs.
|
Ann Intern Med
|
1985
|
0.78
|
|
99
|
Testosterone selectively increases serum follicle-stimulating hormonal (FSH) but not luteinizing hormone (LH) in gonadotropin-releasing hormone antagonist-treated male rats: evidence for differential regulation of LH and FSH secretion.
|
Biol Reprod
|
1987
|
0.78
|
|
100
|
Androgens are not major down-regulators of androgen receptor levels during growth of the immature rat penis .
|
J Steroid Biochem Mol Biol
|
1996
|
0.78
|
|
101
|
Effect of testosterone enanthate on testis size.
|
J Urol
|
1981
|
0.78
|
|
102
|
Testosterone dose-dependency of sexual and nonsexual behaviors in the gonadotropin-releasing hormone antagonist-treated male rat.
|
J Androl
|
1989
|
0.78
|
|
103
|
Regulation of testicular inhibin subunit messenger ribonucleic acid levels in vivo: effects of hypophysectomy and selective follicle-stimulating hormone replacement.
|
Endocrinology
|
1989
|
0.78
|
|
104
|
Nutritional influences on sexual maturation in the rat.
|
Fed Proc
|
1980
|
0.78
|
|
105
|
Gonadotropin-releasing hormone analog and testosterone synergistically inhibit spermatogenesis.
|
Endocrinology
|
1981
|
0.78
|
|
106
|
Pituitary receptor site blockade by a gonadotropin-releasing hormone antagonist in vivo: mechanism of action.
|
Science
|
1982
|
0.78
|
|
107
|
Separation of germ cell apoptosis from toxin-induced cell death by necrosis using in situ end-labeling histochemistry after glutaraldehyde fixation.
|
Tissue Cell
|
1997
|
0.78
|
|
108
|
Pharmacokinetics of gonadotropin-releasing hormone and its analogs.
|
Endocr Rev
|
1986
|
0.78
|
|
109
|
Norepinephrine increases beta-receptors and adenylate cyclase in canine myocardium.
|
Am J Physiol
|
1984
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0.77
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110
|
Induction of azoospermia in normal men with combined Nal-Glu gonadotropin-releasing hormone antagonist and testosterone enanthate.
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J Clin Endocrinol Metab
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1992
|
0.77
|
|
111
|
Hypothalamic hypogonadism.
|
Spec Top Endocrinol Metab
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1985
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0.77
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112
|
Expression of the androgen receptor gene in rat penile tissue and cells during sexual maturation.
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Endocrinology
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1991
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0.77
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113
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Hormone production by the pituitary and testes of male C57BL/6J mice during aging.
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Endocrinology
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1977
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0.77
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114
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Feedback control of FSH in the male: role of oestrogen.
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Acta Endocrinol (Copenh)
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1973
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0.77
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115
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Oligozoospermia induced by exogenous testosterone is associated with normal functioning residual spermatozoa.
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Fertil Steril
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1997
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0.77
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116
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Hormonal effects of single gonadotropin-releasing hormone antagonist doses in men.
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J Clin Endocrinol Metab
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1988
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0.77
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117
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Testicular histology following chronic gonadotropin-releasing hormone agonist treatment.
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Fertil Steril
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1984
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0.77
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118
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Feedback regulation of gonadotropin secretion in men.
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J Urol
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1973
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0.77
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119
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The role of testicular sensitivity to gonadotropins in sexual maturation of the male rat.
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J Steroid Biochem
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1975
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0.77
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120
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Synergistic role of progestogens in estrogen induction of LH and FSH surge.
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Endocrinology
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1972
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0.77
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121
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Lack of a direct effect of gonadotropin hormone-releasing hormone agonist on human testicular steroidogenesis.
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J Clin Endocrinol Metab
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1987
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0.77
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122
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Hormonal effects of gonadotropin-releasing hormone (GnRH) agonist in the human male. III. Effects of long term combined treatment with GnRH agonist and androgen.
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J Clin Endocrinol Metab
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1985
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0.77
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123
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Effect of undernutrition and amino acid deficiency on the timing of puberty in rats.
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Pediatr Res
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1976
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0.77
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124
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Adrenalectomy and castration in the genetically obese (ob/ob) mouse.
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Obes Res
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1993
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0.76
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125
|
Control of LH and FSH secretion in the male: Evidence that aromatization of androgens to estradiol is not required for inhibition of gonadotropin secretion.
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Steroids
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1972
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0.76
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126
|
Down-regulation of pituitary gonadotropin secretion in postmenopausal females by continuous gonadotropin-releasing hormone administration.
|
J Clin Endocrinol Metab
|
1981
|
0.76
|
|
127
|
Effect of GnRH superactive analogs (alone and combined with androgen) on testicular function in man and experimental animals.
|
J Steroid Biochem
|
1983
|
0.76
|
|
128
|
Pharmacokinetics, bioefficacy, and safety of sublingual testosterone cyclodextrin in hypogonadal men: comparison to testosterone enanthate--a clinical research center study.
|
J Clin Endocrinol Metab
|
1995
|
0.76
|
|
129
|
The stimulatory and down-regulatory effects of a gonadotropin-releasing hormone agonist in man.
|
J Clin Endocrinol Metab
|
1984
|
0.76
|
|
130
|
Male gonadal dysfunction.
|
Clin Endocrinol Metab
|
1985
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0.76
|
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131
|
Suppression of human spermatogenesis by depot androgen: potential for male contraception.
|
J Steroid Biochem
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1979
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0.76
|
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132
|
Effects of gonadotropin-releasing hormone analogs on cis-platinum-induced spermatogenic damage.
|
Int J Androl
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1988
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0.76
|
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133
|
Somatostatin-14 and -28 in the male rat reproductive system.
|
Life Sci
|
1984
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0.76
|
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134
|
Reproductive hormonal axis of the male rat in experimental hypothyroidism.
|
Endocrinology
|
1978
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0.76
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135
|
Regulation of alpha and luteinizing hormone beta subunit messenger ribonucleic acids during stimulatory and downregulatory phases of gonadotropin-releasing hormone action.
|
Biol Reprod
|
1988
|
0.76
|
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136
|
The effect of aspirin (prostaglandin synthetase inhibitor) on ovulation.
|
Fertil Steril
|
1978
|
0.76
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137
|
Follicle-stimulating hormone (FSH) escape during chronic gonadotropin-releasing hormone (GnRH) agonist and testosterone treatment.
|
J Androl
|
1995
|
0.76
|
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138
|
Secondary amenorrhea in obesity: etiologic role of weight-related androgen excess.
|
Fertil Steril
|
1978
|
0.76
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