Published in Clin Sci (Lond) on April 01, 1979
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Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors. J Natl Cancer Inst (2000) 5.14
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Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging. Neoplasia (2001) 2.97
Monitoring early response of experimental brain tumors to therapy using diffusion magnetic resonance imaging. Clin Cancer Res (1997) 2.96
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Metabolic activities of the isolated perfused rat kidney. Biochem J (1967) 2.41
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Carbohydrate metabolism of the perfused rat liver. Biochem J (1967) 2.08
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3-D FLASH imaging using a single surface coil and a new adiabatic pulse, BIR-4. Invest Radiol (1990) 1.88
Sodium reabsorption in the perfused rat kidney. Am J Physiol (1973) 1.82
Brief report: organic osmolytes in the brain of an infant with hypernatremia. N Engl J Med (1994) 1.81
Ammonia metabolism. Am J Physiol (1978) 1.73
Applications of magnetic resonance in model systems: cancer therapeutics. Neoplasia (2000) 1.72
Enzyme distribution along the nephron. Kidney Int (1984) 1.60
Alzheimer disease: depiction of increased cerebral myo-inositol with proton MR spectroscopy. Radiology (1993) 1.58
Tricarboxylic acid cycle of glia in the in vivo human brain. NMR Biomed (2002) 1.57
Cerebral metabolic disturbances in patients with subacute and chronic diabetes mellitus: detection with proton MR spectroscopy. Radiology (1992) 1.47
Accumulation of methylsulfonylmethane in the human brain: identification by multinuclear magnetic resonance spectroscopy. Toxicol Lett (2001) 1.44
Induction of cytotoxic oxidative stress by D-alanine in brain tumor cells expressing Rhodotorula gracilis D-amino acid oxidase: a cancer gene therapy strategy. Hum Gene Ther (1998) 1.43
Diffusion MRI detects early events in the response of a glioma model to the yeast cytosine deaminase gene therapy strategy. Gene Ther (2000) 1.42
31P NMR examination of two patients with NADH-CoQ reductase deficiency. Nature (1982) 1.37
Diffusion imaging for evaluation of tumor therapies in preclinical animal models. MAGMA (2004) 1.33
Indomethacin potentiates the vasoconstrictor actions of angiotensin II in normal man. Prostaglandins (1976) 1.33
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Improved function with amino acids in the isolated perfused kidney. Am J Physiol (1982) 1.23
Poly (lactic-glycolic) acid copolymer encapsulation of recombinant adenovirus reduces immunogenicity in vivo. Gene Ther (1998) 1.19
Assessment of the role of the glutathione and pentose phosphate pathways in the protection of primary cerebrocortical cultures from oxidative stress. J Neurochem (1996) 1.14
Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease. Magn Reson Med (1994) 1.13
Metabolic imaging of mild traumatic brain injury. Brain Imaging Behav (2012) 1.12
The potential of 5-fluorocytosine/cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model. Gene Ther (2002) 1.12
Low-renin hypertension. Kidney Int (1974) 1.12
In vivo magnetic resonance imaging of hyperpolarized silicon particles. Nat Nanotechnol (2013) 1.08
Growth kinetics and treatment response of the intracerebral rat 9L brain tumor model: a quantitative in vivo study using magnetic resonance imaging. Clin Cancer Res (1995) 1.07
Effect of inhibition of gluconeogenesis on ammonia production in the perfused rat kidney. Clin Sci Mol Med (1976) 1.07
Relationship of renal ammonia production and potassium homeostasis. Kidney Int (1977) 1.07
Early castration reduces prostatic carcinogenesis in transgenic mice. Urology (1999) 1.07
Direct determination of the N-acetyl-L-aspartate synthesis rate in the human brain by (13)C MRS and [1-(13)C]glucose infusion. J Neurochem (2001) 1.05
Clinical magnetic susceptibility mapping of the brain. J Comput Assist Tomogr (1987) 1.04
Nephropathy associated with heat stress and exercise. Ann Intern Med (1967) 1.04
The effect of experimental bile-duct obstruction on critical biosynthetic functions of the liver. Br J Surg (1972) 1.04
Human cerebral osmolytes during chronic hyponatremia. A proton magnetic resonance spectroscopy study. J Clin Invest (1995) 1.03
1-(13)C glucose magnetic resonance spectroscopy of pediatric and adult brain disorders. NMR Biomed (2001) 1.03
Protection of acid-base balance by pH regulation of acid production. N Engl J Med (1998) 1.03
Activation of oxoglutarate dehydrogenase in the kidney in response to acute acidosis. Biochem J (1980) 1.02
Three methods of calibration in quantitative proton MR spectroscopy. J Magn Reson B (1995) 1.02
Vasopressin-resistant hyposthenuria in advanced chronic renal disease. N Engl J Med (1969) 1.02
Role of increased cerebral myo-inositol in the dementia of Down syndrome. Magn Reson Med (1995) 1.01
Childhood mitochondrial myopathy with ophthalmoplegia. J Neurol Sci (1981) 1.01
Longitudinal cohort analysis of lethal prostate cancer progression in transgenic mice. J Urol (1998) 1.00
Tuberous sclerosis and chronic renal failure. Potential confusion with polycystic kidney disease. Am J Med (1969) 0.99
Magnetic resonance imaging of ethyl-nitrosourea-induced rat gliomas: a model for experimental therapeutics of low-grade gliomas. J Neurooncol (2001) 0.99
The importance of pH in renal preservation. Transplant Proc (1981) 0.98
A 15N-n.m.r. study of cerebral, hepatic and renal nitrogen metabolism in hyperammonaemic rats. Biochem J (1990) 0.98
[1-13C]glucose MRS in chronic hepatic encephalopathy in man. Magn Reson Med (2001) 0.98
Selective distal nephron damage during isolated kidney perfusion. Kidney Int (1981) 0.98
Quantitative proton-decoupled 31P MRS and 1H MRS in the evaluation of Huntington's and Parkinson's diseases. Neurology (1998) 0.97
The isolated perfused rat kidney. Clin Sci Mol Med Suppl (1978) 0.96
Yeast cytosine deaminase improves radiosensitization and bystander effect by 5-fluorocytosine of human colorectal cancer xenografts. Cancer Res (2000) 0.96
Fusion of the HSV-1 tegument protein vp22 to cytosine deaminase confers enhanced bystander effect and increased therapeutic benefit. Gene Ther (2006) 0.96
Identification of cerebral acetone by 1H-MRS in patients with epilepsy controlled by ketogenic diet. MAGMA (1999) 0.95
Morphologic effects of hGRH gene expression on the pituitary, liver, and pancreas of MT-hGRH transgenic mice. An in situ hybridization analysis. Am J Pathol (1992) 0.95
Evidence from proton magnetic resonance spectroscopy for a metabolic cascade of neuronal damage in shaken baby syndrome. Pediatrics (1997) 0.94
Enhancement of hyperthermia effect in vivo by amiloride and DIDS. Int J Radiat Oncol Biol Phys (1993) 0.94
Enzyme/prodrug therapy for head and neck cancer using a catalytically superior cytosine deaminase. Hum Gene Ther (1999) 0.94
Developmental changes in choline- and ethanolamine-containing compounds measured with proton-decoupled (31)P MRS in in vivo human brain. Magn Reson Med (1999) 0.93
Mechanism of action of lonidamine in the 9L brain tumor model involves inhibition of lactate efflux and intracellular acidification. J Neurooncol (1998) 0.92
Oxidative stress in the central nervous system: monitoring the metabolic response using the pentose phosphate pathway. Dev Neurosci (1994) 0.92
Diuretic-induced hypokalemia. Kidney Int (1985) 0.91
15N n.m.r. measurement of the in vivo rate of glutamine synthesis and utilization at steady state in the brain of the hyperammonaemic rat. Biochem J (1993) 0.91
Response of ammonia metabolism to acute acidosis. Kidney Int (1984) 0.91
31P saturation transfer and phosphocreatine imaging in the monkey brain. Proc Natl Acad Sci U S A (1991) 0.91
Localized 1H NMR spectroscopy in patients with chronic hepatic encephalopathy. Analysis of changes in cerebral glutamine, choline and inositols. NMR Biomed (1991) 0.91
Dynamic measurements of cerebral pentose phosphate pathway activity in vivo using [1,6-13C2,6,6-2H2]glucose and microdialysis. J Neurochem (1995) 0.91
Short-echo time proton MR spectroscopy in the presence of gadolinium. J Comput Assist Tomogr (2001) 0.90
Application of 31P n.m.r. to inborn errors of muscle metabolism. Biochem Soc Trans (1983) 0.90
Glucose metabolism in renal tubular function. Kidney Int (1986) 0.90
Rate of glutamate synthesis from leucine in rat brain measured in vivo by 15N NMR. J Neurochem (1998) 0.90
Magnetic resonance methods for measurement of disease progression in rheumatoid arthritis. Magn Reson Imaging (1993) 0.90
The effect of uncomplicated potassium depletion on urine acidification. J Clin Invest (1970) 0.89
The role of intrarenal pH in regulation of ammoniagenesis: [31P]NMR studies of the isolated perfused rat kidney. J Physiol (1981) 0.89
Magnetic resonance imaging with adiabatic pulses using a single surface coil for RF transmission and signal detection. Magn Reson Med (1989) 0.89
31P magnetization transfer studies in the monkey brain. Magn Reson Med (1992) 0.89
13C enrichment of extracellular neurotransmitter glutamate in rat brain--combined mass spectrometry and NMR studies of neurotransmitter turnover and uptake into glia in vivo. Cell Mol Biol (Noisy-le-grand) (2003) 0.88
A 15N NMR study of in vivo cerebral glutamine synthesis in hyperammonemic rats. NMR Biomed (1993) 0.88
Potassium transport by the isolated perfused kidney. J Clin Invest (1975) 0.88
Diagnosis of hepatic encephalopathy by proton magnetic resonance spectroscopy. Lancet (1990) 0.88
Redox state of cytochrome aa3 in isolated perfused rat kidney. Am J Physiol (1982) 0.88
Novel peak assignments of in vivo (13)C MRS in human brain at 1.5 T. J Magn Reson (2000) 0.87
Proton magnetic resonance spectroscopy in children with acute central nervous system injury. Pediatr Neurol (1995) 0.87
In vivo activity of glutaminase in the brain of hyperammonaemic rats measured by 15N nuclear magnetic resonance. Biochem J (1995) 0.86
Effect of decrease in bicarbonate concentration on metabolism of the isolated perfused rat kidney. Clin Sci (Lond) (1979) 0.85
Mechanisms of chronic hypoxia-induced renal cell growth. Kidney Int (1999) 0.85
Experimental gliosarcoma induces chemokine receptor expression in rat brain. Exp Neurol (2000) 0.85
Effect of respiratory acidosis on intracellular pH of the proximal tubule. Am J Physiol (1986) 0.85
Rocking promotes differentiated properties in LLC-PK cells by improved oxygenation. Am J Physiol (1989) 0.85