Published in Rev Clin Basic Pharm on April 16, 1987
Adenosine: a mediator of the sleep-inducing effects of prolonged wakefulness. Science (1997) 3.40
Neurobiological mechanisms for the regulation of mammalian sleep-wake behavior: reinterpretation of historical evidence and inclusion of contemporary cellular and molecular evidence. Neurosci Biobehav Rev (2007) 1.57
The energy hypothesis of sleep revisited. Prog Neurobiol (2008) 1.47
Control and function of the homeostatic sleep response by adenosine A1 receptors. J Neurosci (2009) 1.40
Sleep fragmentation elevates behavioral, electrographic and neurochemical measures of sleepiness. Neuroscience (2007) 1.27
The impact of sleep deprivation on neuronal and glial signaling pathways important for memory and synaptic plasticity. Cell Signal (2012) 0.96
Caffeine in the neonatal period induces long-lasting changes in sleep and breathing in adult rats. J Physiol (2009) 0.94
Effects of sleep deprivation on sleep homeostasis and restoration during methadone-maintenance: a [31]P MRS brain imaging study. Drug Alcohol Depend (2009) 0.92
Manipulation of adenosine kinase affects sleep regulation in mice. J Neurosci (2010) 0.91
Sedative effects of Arachis hypogaea L. stem and leaf extracts on sleep-deprived rats. Exp Ther Med (2013) 0.83
Circadian rhythms and sleep--the metabolic connection. Pflugers Arch (2011) 0.79
Time- and behavioral state-dependent changes in posterior hypothalamic GABAA receptors contribute to the regulation of sleep. PLoS One (2014) 0.78
Nitric oxide modulates the discharge rate of basal forebrain neurons. Psychopharmacology (Berl) (2008) 0.78
Future approaches to therapeutic hypothermia: a symposium report. Temperature (Austin) (2015) 0.76
Cordycepin Increases Nonrapid Eye Movement Sleep via Adenosine Receptors in Rats. Evid Based Complement Alternat Med (2013) 0.76
IV ATP potentiates midazolam sedation as assessed by bispectral index. Anesth Prog (2014) 0.75
The Role of Adenosine in the Maturation of Sleep Homeostasis in Rats. J Neurophysiol (2016) 0.75
Adenosine A1 receptor agonist GR79236 suppresses apnea during all sleep stages in the rat. Sleep (1997) 1.38
Adenosine analogs and sleep in rats. J Pharmacol Exp Ther (1984) 1.26
Role of adenosine in sleep and temperature regulation in the preoptic area of rats. Pharmacol Biochem Behav (1991) 1.16
Role of peripheral serotonin in the regulation of central sleep apneas in rats. Chest (1999) 0.98
Mirtazapine, a mixed-profile serotonin agonist/antagonist, suppresses sleep apnea in the rat. Am J Respir Crit Care Med (1999) 0.98
Low-frequency oscillations of cortical oxidative metabolism in waking and sleep. J Cereb Blood Flow Metab (1988) 0.97
Effects of chronic administration of caffeine on adenosine A1 and A2 receptors in rat brain. Brain Res Bull (1988) 0.90
Effects of inspired gas on sleep-related apnea in the rat. J Appl Physiol (1985) (1996) 0.89
REM sleep deprivation up-regulates adenosine A1 receptors. Brain Res (1987) 0.87
Monoaminergic system lesions increase post-sigh respiratory pattern disturbance during sleep in rats. Physiol Behav (2006) 0.87
The dose-response effects of caffeine on sleep in rats. Brain Res (1987) 0.87
N6 (L-phenylisopropyl) adenosine (L-PHA) increases slow-wave sleep (S2) and decreases wakefulness in rats. Brain Res (1982) 0.85
A comparison of the effects of caffeine, 8-cyclopentyltheophylline, and alloxazine on sleep in rats. Possible roles of central nervous system adenosine receptors. Neuropsychopharmacology (1990) 0.85
A comparison of the dose response effects of pyrimidine ribonucleosides and adenosine on sleep in rats. Psychopharmacology (Berl) (1985) 0.84
Hypnotic effects of deoxycorformycin in rats. Brain Res (1983) 0.83
Diazepam suppresses sleep apneas in rats. Am J Respir Crit Care Med (1998) 0.83
Sleep-disordered respiration in phenotypically normotensive, genetically hypertensive rats. Am J Respir Crit Care Med (2000) 0.83
Cardiopulmonary control in sleeping Sprague-Dawley rats treated with hydralazine. J Appl Physiol (1985) (1997) 0.82
R-zacopride, a 5-HT3 antagonist/5-HT4 agonist, reduces sleep apneas in rats. Pharmacol Biochem Behav (2001) 0.81
Desensitization of adenosine and dopamine receptors in rat brain after treatment with adenosine analogs. J Pharmacol Exp Ther (1988) 0.81
Sleep apnea in normal and REM sleep-deprived normotensive Wistar-Kyoto and spontaneously hypertensive (SHR) rats. Physiol Behav (1996) 0.81
C-fiber activation exacerbates sleep-disordered breathing in rats. Sleep Breath (2004) 0.80
The effects of adenosine and 2'-deoxycoformycin on sleep and wakefulness in rats. Neuropharmacology (1983) 0.80
Adenosine analogues modulate the incidence of sleep apneas in rats. Pharmacol Biochem Behav (1995) 0.79
Hydralazine reduces elevated sleep apnea index in spontaneously hypertensive (SHR) rats to equivalence with normotensive Wistar-Kyoto rats. Sleep (1996) 0.78
Circadian variation of [3H]N6-(L-phenylisopropyl)adenosine binding in rat brain. Neurosci Lett (1984) 0.78
Effect of tryptophan on sleep in the rat. Neuropharmacology (1980) 0.78
Role of peripheral adenosine A(1) receptors in the regulation of sleep apneas in rats. Exp Neurol (1999) 0.77
An inexpensive sleep-wake state analyzer for the rat. Physiol Behav (1988) 0.77
Sleep suppressant action of fenfluramine in rats. II. Evidence against the involvement of presynaptic serotonergic mechanism. J Pharmacol Exp Ther (1983) 0.77
Sleep suppressant action of fenfluramine in rats. I. Relation to postsynaptic serotonergic stimulation. J Pharmacol Exp Ther (1983) 0.76
The effect of soluflazine on adenosine receptors in the rat brain. Neuropharmacology (1991) 0.76
Muramyl dipeptide does not induce slow-wave sleep or fever in rats. Peptides (1984) 0.76
Protoveratrines A and B increase sleep apnea index in Sprague-Dawley rats. J Appl Physiol (1985) (1997) 0.76
Effects of cholinomimetic agents on pentobarbital anesthesia in mice. Res Commun Chem Pathol Pharmacol (1978) 0.76
Effects of prolonged administration of triazolam on adenosine A1 and A2 receptors in the brain of rats. Brain Res (1989) 0.76
Effects of ethanol injection to the preoptic area on sleep and temperature in rats. Alcohol (1992) 0.76
Effects of REM sleep deprivation and desipramine on beta-adrenergic binding sites in rat brain. Brain Res (1982) 0.76
p-SPA, a peripheral adenosine A1 analogue, reduces sleep apneas in rats. Pharmacol Biochem Behav (1996) 0.76
Chronic administration of diazepam downregulates adenosine receptors in the rat brain. Pharmacol Biochem Behav (1988) 0.76
Effects of diazepam on sleep, temperature, 5-hydroxyindoleacetic and homovanillic acids in cisternal cerebrospinal fluid of cats. Pharmacology (1979) 0.75
Phenoxybenzamine and bromocriptine attenuate need for REM sleep in rats. Pharmacol Biochem Behav (1981) 0.75
[3H]N6-(L-Phenylisopropyl) adenosine binding in brains from young and old rats. Neurobiol Aging (1984) 0.75
Elimination of REM sleep rebound in rats by alpha-adrenoreceptor blockers, phentolamine and phenoxybenzamine. Pharmacol Biochem Behav (1980) 0.75
Radioligand binding to adenosine receptors and adenosine uptake sites in different brain regions of normal and narcoleptic dogs. Pharmacol Biochem Behav (1991) 0.75
The influence of deprivation of paradoxicalx sleep on glycogen content in various brain structures of the cat. Experientia (1967) 0.75
Hypnotic effect of tryptophan analog in rats. Pharmacol Biochem Behav (1979) 0.75
Variation in calcium content of cerebrospinal fluid after excitation. East Afr Med J (1971) 0.75
Neither REM sleep deprivation nor rebound influences 3H-diazepam binding n rat brain. Physiol Behav (1983) 0.75
Quipazine has a biphasic effect on slow wave sleep and reduces REM sleep rebound in REM sleep deprived rats. Brain Res Bull (1982) 0.75
Caffeine produces REM sleep rebound in rats. Brain Res (1980) 0.75
Methysergide blocks the sleep suppressant action of quipazine in rats. Psychopharmacology (Berl) (1982) 0.75
Amphetamine abolishes REM sleep rebound in rats: effect of single injection. Brain Res (1981) 0.75
Lack of effect of 1-methylisoguanosine on sleep in rats. Neuropharmacology (1985) 0.75
Bromocriptine, dihydroergotoxine and sleep in rats: effects of repeated administration. Gerontology (1981) 0.75
Desensitization of adenosine A2 receptors in the striatum of the rat following chronic treatment with diazepam. Neuropharmacology (1988) 0.75
The effect of soluflazine on sleep in rats. Neuropharmacology (1991) 0.75
Convulsion-producing property of the dialyzable glycopeptide preparation from whole rat brain. Neuropharmacology (1974) 0.75
Sleep suppressant action of quipazine: relation to central serotonergic stimulation. Pharmacol Biochem Behav (1981) 0.75
Selective increase in brain dopamine metabolism during REM sleep rebound in the rat. Physiol Behav (1981) 0.75
Comparison of effects of paradoxical sleep deprivation and immobilization stress on 5-hydroxyindoleacetic acid in cerebrospinal fluid. Brain Res (1973) 0.75
5-Hydroxyindoleacetic acid in cerebrospinal fluid: measurements in wakefulness, slow-wave and paradoxical sleep. Brain Res (1973) 0.75
Diazepam and midazolam increase light slow-wave sleep (SWS1) and decrease wakefulness in rats. Brain Res (1984) 0.75
Increase of 5-hydroxyindoleacetic acid and homovanillic acid in cisternal fluid of cats subjected to stress. J Neurochem (1976) 0.75
Human tryptamine metabolism decreases during night sleep. Brain Res Bull (1983) 0.75
5-Hydroxyindoleacetic acid in cerebrospinal fluid:an indicator of slow-wave sleep. Brain Res (1975) 0.75
Comparison effects of electrical stimulation of preoptic area, anterior hypothalamus and dorsal raphe nucleus on 5-hydroxyindoleacetic acid in cerebrospinal fluid and behavior. Brain Res (1974) 0.75
The effects of reserpine, L-dopa and 5-hydroxytryptophan on 5-hydroxyindoleacetic and homovanillic acids in cerebrospinal fluid, behaviour and EEG in cats. Neuropharmacology (1976) 0.75
The effect of adrenaline on different states of sleep. Experientia (1968) 0.75
The selective effects of alpha-methyl aromatic amino acids on brain monoamine metabolites and behavior in cats. Res Commun Chem Pathol Pharmacol (1975) 0.75
Gamma-hydroxybutyrate in CSF during sleep and wakefulness. Res Commun Chem Pathol Pharmacol (1976) 0.75
Chronic Ro 15-1788 treatment increases REM sleep in rats. Brain Res Bull (1991) 0.75
alpha-Flupenthixol increases slow-wave in rats: effect of dopamine receptor blockade. Neuropharmacology (1982) 0.75
A simplified method for monitoring the cytochrome aa3 redox state in bilateral cortical areas of unanesthetized cats. Brain Res (1987) 0.75
Similar effects of tryptophan and sleep on cisternal cerebrospinal fluid 5-hydroxyindoleacetic and homovanillic acids in cats. Brain Res (1977) 0.75
Effects of carbachol and nicotine injected into the cerebral ventricles on electromyogram of conscious cats. Brain Res Bull (1977) 0.75
Prenatal exposure to diazepam results in enduring reductions in brain receptors and deep slow wave sleep. Brain Res (1985) 0.75
Effects of methysergide in cats deprived of paradoxical sleep. Res Commun Chem Pathol Pharmacol (1976) 0.75
L-Tryptophan's effects on brain chemistry and sleep in cats and rats: a review. Neurosci Biobehav Rev (1982) 0.75
Monoamine changes in the brain of cats during slow-wave sleep. Science (1976) 0.75
Effect of interhemispheric transection on the EEG patterns in sleep and wakefulness in monkeys. Electroencephalogr Clin Neurophysiol (1967) 0.75
Effect of REM sleep deprivation on sleep apneas in rats. Exp Neurol (1996) 0.75
Effects of bromocriptine and alpha-flupenthixol on sleep in REM sleep deprived rats. Life Sci (1979) 0.75
Inhibition of glucose utilization for acetylcholine synthesis by cerebrospinal fluid. J Neurochem (1976) 0.75