PubRank

E L Hewlett

Author PubWeight™ 148.06‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Tn5-induced mutations affecting virulence factors of Bordetella pertussis. Infect Immun 1983 8.49
2 Virulence factors of Bordetella pertussis. Annu Rev Microbiol 1986 6.41
3 Induction of a novel morphological response in Chinese hamster ovary cells by pertussis toxin. Infect Immun 1983 5.03
4 Genetic diversity and relationships in populations of Bordetella spp. J Bacteriol 1986 4.48
5 Extracytoplasmic adenylate cyclase of Bordetella pertussis. Proc Natl Acad Sci U S A 1976 3.57
6 Pertussis toxin and extracytoplasmic adenylate cyclase as virulence factors of Bordetella pertussis. J Infect Dis 1984 3.48
7 Identification of the predominant substrate for ADP-ribosylation by islet activating protein. J Biol Chem 1983 3.11
8 Inhibitors of receptor-mediated endocytosis block the entry of Bacillus anthracis adenylate cyclase toxin but not that of Bordetella pertussis adenylate cyclase toxin. Infect Immun 1988 2.69
9 Nucleotide sequence and characterization of a repetitive DNA element from the genome of Bordetella pertussis with characteristics of an insertion sequence. J Gen Microbiol 1988 2.46
10 Bordetella pertussis adenylate cyclase toxin and hemolytic activities require a second gene, cyaC, for activation. J Bacteriol 1991 1.90
11 Intracellular localization of the dermonecrotic toxin of Bordetella pertussis. Infect Immun 1979 1.83
12 Internal lysine palmitoylation in adenylate cyclase toxin from Bordetella pertussis. Science 1994 1.78
13 Activation by thiol of the latent NAD glycohydrolase and ADP-ribosyltransferase activities of Bordetella pertussis toxin (islet-activating protein). J Biol Chem 1983 1.74
14 N-Acetyl-D-galactosamine-inhibitable adherence lectin of Entamoeba histolytica. I. Partial purification and relation to amoebic virulence in vitro. J Infect Dis 1985 1.67
15 ADP-ribosylation of adenylate cyclase by pertussis toxin. Effects on inhibitory agonist binding. J Biol Chem 1984 1.67
16 Toxins of Vibrio cholerae and Escherichia coli stimulate adenyl cyclase in rat fat cells. Nature 1974 1.58
17 Experimental infection of mongrel dogs with Giardia lamblia cysts and cultured trophozoites. J Infect Dis 1982 1.56
18 Pertussis toxin effects on T lymphocytes are mediated through CD3 and not by pertussis toxin catalyzed modification of a G protein. J Immunol 1989 1.45
19 Inhibition of monocyte oxidative responses by Bordetella pertussis adenylate cyclase toxin. J Immunol 1987 1.45
20 Construction and characterization of Bordetella pertussis mutants lacking the vir-regulated P.69 outer membrane protein. Mol Microbiol 1991 1.42
21 Pertussis toxin inhibits enkephalin stimulation of GTPase of NG108-15 cells. J Biol Chem 1983 1.41
22 Adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis. Different processes for interaction with and entry into target cells. J Biol Chem 1989 1.39
23 Species specificity of Bordetella adherence to human and animal ciliated respiratory epithelial cells. Infect Immun 1983 1.36
24 Rhodopsin-enhanced GTPase activity of the inhibitory GTP-binding protein of adenylate cyclase. J Biol Chem 1984 1.33
25 Virulence factors of Bordetella bronchiseptica associated with the production of infectious atrophic rhinitis and pneumonia in experimentally infected neonatal swine. Infect Immun 1987 1.31
26 Lethal effect of phenothiazine neuroleptics on the pathogenic protozoan Leishmania donovani. Science 1982 1.30
27 Giardia lamblia infection of suckling mice. J Infect Dis 1983 1.29
28 International Bordetella pertussis assay standardization and harmonization meeting report. Centers for Disease Control and Prevention, Atlanta, Georgia, United States, 19-20 July 2007. Vaccine 2008 1.25
29 Pertussis toxin or phorbol 12-myristate 13-acetate can distinguish between epidermal growth factor- and angiotensin-stimulated signals in hepatocytes. Proc Natl Acad Sci U S A 1986 1.20
30 Epitope mapping of monoclonal antibodies against Bordetella pertussis adenylate cyclase toxin. Infect Immun 1999 1.19
31 Adenylate cyclase toxin from Bordetella pertussis produces ion conductance across artificial lipid bilayers in a calcium- and polarity-dependent manner. J Biol Chem 1994 1.18
32 Pentamidine for the treatment of Pneumocystis carinii pneumonia and other protozoal diseases. Ann Intern Med 1985 1.18
33 Antileishmanial activity of chlorpromazine. Antimicrob Agents Chemother 1984 1.17
34 Niclosamide therapy for tapeworm infections. Ann Intern Med 1985 1.17
35 Characterization of antibody inhibiting adherence of Bordetella pertussis to human respiratory epithelial cells. J Clin Microbiol 1984 1.15
36 Hemolytic activity of adenylate cyclase toxin from Bordetella pertussis. FEBS Lett 1991 1.15
37 Role of Ni in coupling angiotensin receptors to inhibition of adenylate cyclase in hepatocytes. J Biol Chem 1985 1.13
38 NIH conference. Cyclic nucleotides: mediators of bacterial toxin action in disease. Ann Intern Med 1984 1.13
39 Biphasic effect of pertussis vaccine on serum insulin in mice. Infect Immun 1983 1.11
40 Stimulation of the thiol-dependent ADP-ribosyltransferase and NAD glycohydrolase activities of Bordetella pertussis toxin by adenine nucleotides, phospholipids, and detergents. Biochemistry 1986 1.10
41 Hemolytic, but not cell-invasive activity, of adenylate cyclase toxin is selectively affected by differential fatty-acylation in Escherichia coli. J Biol Chem 1995 1.10
42 Does enteropathogenic Escherichia coli produce heat-labile enterotoxin, heat-stable enterotoxins a or b, or cholera toxin A subunits? Infect Immun 1984 1.10
43 Genetic studies of the molecular basis of whooping cough. Dev Biol Stand 1985 1.09
44 Neutralizing antibodies to adenylate cyclase toxin promote phagocytosis of Bordetella pertussis by human neutrophils. Infect Immun 2000 1.09
45 Newly secreted adenylate cyclase toxin is responsible for intoxication of target cells by Bordetella pertussis. Mol Microbiol 2004 1.07
46 Bordetella extracytoplasmic adenylate cyclase: actions as a bacterial toxin. Dev Biol Stand 1985 1.06
47 Regulation of Bordetella pertussis extracytoplasmic adenylate cyclase. Adv Cyclic Nucleotide Res 1978 1.06
48 ADP-ribosylation of transducin by pertussis toxin. J Biol Chem 1985 1.05
49 Human serologic response to envelope-associated proteins and adenylate cyclase toxin of Bordetella pertussis. J Infect Dis 1991 1.04
50 Anthrax toxin components stimulate chemotaxis of human polymorphonuclear neutrophils. Proc Soc Exp Biol Med 1985 1.04
51 Amino acid-specific ADP-ribosylation. Sensitivity to hydroxylamine of [cysteine(ADP-ribose)]protein and [arginine(ADP-ribose)]protein linkages. J Biol Chem 1985 1.03
52 Effects of guanyl nucleotides and rhodopsin on ADP-ribosylation of the inhibitory GTP-binding component of adenylate cyclase by pertussis toxin. J Biol Chem 1984 1.03
53 Pertussis toxin treatment attenuates some effects of insulin in BC3H-1 murine myocytes. J Biol Chem 1988 1.02
54 Activation of prokaryotic adenylate cyclase by calmodulin. Ann N Y Acad Sci 1980 0.98
55 Promotion of lipolysis in rat adipocytes by pertussis toxin: reversal of endogenous inhibition. Proc Natl Acad Sci U S A 1983 0.98
56 A protein activator for the adenylate cyclase of Bordetella pertussis. J Biol Chem 1979 0.98
57 Adenyl cyclase in Bordetella pertussis vaccines. J Infect Dis 1977 0.97
58 Phorbol esters enhance the cyclic GMP response of T84 cells to the heat-stable enterotoxin of Escherichia coli (STa). Infect Immun 1990 0.96
59 Susceptibility of Bordetella species to growth inhibition and killing by chlorpromazine. Antimicrob Agents Chemother 1983 0.94
60 Translocation-specific conformation of adenylate cyclase toxin from Bordetella pertussis inhibits toxin-mediated hemolysis. J Bacteriol 2001 0.94
61 Membrane depolarization prevents cell invasion by Bordetella pertussis adenylate cyclase toxin. J Biol Chem 1995 0.94
62 Protection against infection with Giardia muris by milk containing antibody to Giardia. J Infect Dis 1981 0.94
63 Role of pertussis toxin A subunit in neutrophil migration and vascular permeability. Infect Immun 1997 0.94
64 Lectin binding by Giardia lamblia. Infect Immun 1981 0.93
65 Pertussis toxin-catalyzed ADP-ribosylation: effects on the coupling of inhibitory receptors to the adenylate cyclase system. J Recept Res 1984 0.92
66 Pertussis toxin blocks the somatostatin-induced inhibition of growth hormone release and adenosine 3',5'-monophosphate accumulation. Endocrinology 1983 0.91
67 Protein kinase C enhances growth hormone releasing factor (1-40)-stimulated cyclic AMP levels in anterior pituitary. Actions of somatostatin and pertussis toxin. J Biol Chem 1986 0.90
68 Pertussis toxin uncouples dopamine agonist inhibition of prolactin release. Am J Physiol 1983 0.89
69 Adenosine and related compounds counteract tumor necrosis factor-alpha inhibition of neutrophil migration: implication of a novel cyclic AMP-independent action on the cell surface. J Immunol 1990 0.89
70 Murine giardiasis: localization of trophozoites and small bowel histopathology during the course of infection. Am J Trop Med Hyg 1982 0.89
71 Serological correlates of immunity to Bordetella pertussis. Vaccine 1998 0.88
72 Heterologous desensitization of adenylate cyclase with prostaglandin E1 alters sensitivity to inhibitory as well as stimulatory agonists. J Biol Chem 1985 0.88
73 Pertussis toxin from Bordetella pertussis blocks neutrophil migration and neutrophil-dependent edema in response to inflammation. Braz J Med Biol Res 1995 0.88
74 Spurious protein activators of Bordetella pertussis adenylate cyclase. Eur J Biochem 1981 0.86
75 Structural consequences of divalent metal binding by the adenylyl cyclase toxin of Bordetella pertussis. Arch Biochem Biophys 2001 0.86
76 Human pancreatic tumor growth hormone-releasing factor stimulates anterior pituitary adenylate cyclase activity, adenosine 3',5'-monophosphate accumulation, and growth hormone release in a calmodulin-dependent manner. Endocrinology 1984 0.85
77 Increased intracellular cyclic adenosine monophosphate inhibits T lymphocyte-mediated cytolysis by two distinct mechanisms. J Exp Med 1988 0.85
78 Bordetella pertussis: multiple attacks on host cell cyclic AMP regulation. Adv Cyclic Nucleotide Protein Phosphorylation Res 1984 0.85
79 Inhibition of bovine rod outer segment GTPase by Bordetella pertussis toxin. J Biol Chem 1984 0.85
80 Characterization of binding of adenylate cyclase toxin to target cells by flow cytometry. Infect Immun 1999 0.85
81 Enzymatic activity of adenylate cyclase toxin from Bordetella pertussis is not required for hemolysis. FEBS Lett 1992 0.85
82 Pertussis toxin activates platelets through an interaction with platelet glycoprotein Ib. Infect Immun 1994 0.85
83 Use of pyrimethamine-sulfadoxine (Fansidar) in prophylaxis against chloroquine-resistant Plasmodium falciparum and Pneumocystis carinii. Ann Intern Med 1987 0.85
84 Saline lavage: a rapid, effective, and acceptable method for cleansing the gastrointestinal tract. Gastroenterology 1976 0.84
85 Effect of temperature and host factors on the activities of pertussis toxin and Bordetella adenylate cyclase. Biochemistry 1994 0.83
86 A putative mediator of insulin action which inhibits adenylate cyclase and adenosine 3',5'-monophosphate-dependent protein kinase: partial purification from rat liver: site and kinetic mechanism of action. Endocrinology 1987 0.83
87 Inhibition of parathyroid hormone-responsive adenylate cyclase in clonal osteoblast-like cells by transforming growth factor alpha and epidermal growth factor. J Biol Chem 1987 0.83
88 Human pancreatic tumor growth hormone (GH) - releasing factor and cyclic adenosine 3',5'- monophosphate evoke GH release from anterior pituitary cells: the effects of pertussis toxin, cholera toxin, forskolin, and cycloheximide. Endocrinology 1984 0.83
89 Requirement for both choleragen and pertussis toxin to obtain maximal activation of adenylate cyclase in cultured cells. Biochem Biophys Res Commun 1984 0.82
90 Antibodies to Bordetella pertussis adenylate cyclase toxin in neonatal and maternal sera. FEMS Immunol Med Microbiol 1993 0.82
91 Structural and functional properties of a 69-kilodalton outer membrane protein of Bordetella pertussis. Tokai J Exp Clin Med 1988 0.81
92 Pertussis toxin: lessons from biological and biochemical effects in different cells. Adv Cyclic Nucleotide Protein Phosphorylation Res 1984 0.81
93 Escherichia coli alpha-hemolysin (HlyA) is heterogeneously acylated in vivo with 14-, 15-, and 17-carbon fatty acids. J Biol Chem 2000 0.81
94 LH release is facilitated by agents that alter cyclic AMP-generating system. Am J Physiol 1984 0.80
95 Selective primary health care: strategies for control of disease in the developing world. XVII. Pertussis and diphtheria. Rev Infect Dis 1985 0.80
96 Pertussis toxin actions on the pituitary-derived 235-1 clone: effects of PGE1, cholera toxin, and forskolin on cyclic AMP metabolism and prolactin release. J Cyclic Nucleotide Protein Phosphor Res 1983 0.80
97 Transforming growth factor beta enhances parathyroid hormone stimulation of adenylate cyclase in clonal osteoblast-like cells. J Cell Physiol 1990 0.79
98 Effects of adenylate cyclase toxin from Bordetella pertussis on human neutrophil interactions with Coccidioides immitis and Staphylococcus aureus. Infect Immun 1988 0.79
99 Mechanism of enhanced sensitivity to bradykinin in pertussis toxin-treated fibroblasts: toxin increases bradykinin-stimulated prostaglandin formation. Mol Pharmacol 1988 0.79
100 Differential effects of forskolin on LH and GH release. Am J Physiol 1985 0.78
101 Evidence for a functionally active inhibitory guanine nucleotide-binding regulatory protein in the swine ovary. Biochem Biophys Res Commun 1985 0.78
102 Failure of pertussis toxin to inhibit activation of guanylate cyclase by the heat-stable enterotoxin of Escherichia coli (STa) in the T84 cell line. Infect Immun 1989 0.78
103 Pertussis toxin mediates ADP-ribosylation of pituitary membrane proteins. Endocr Res 1986 0.77
104 Actions of cyclic adenosine monophosphate on the cytodifferentiation of ovarian cells: studies in cultured swine granulosa cells using a novel exogenous adenylate cyclase from Bordetella pertussis. Mol Endocrinol 1988 0.77
105 Dopamine decreases 7315a tumor cell prolactin release induced by calcium mobilization. Endocrinology 1985 0.77
106 Effects of pertussis toxin-catalyzed ADP-ribosylation on interactions of transducin and the inhibitory GTP-binding protein of adenylate cyclase with guanyl nucleotides. Biochem Biophys Res Commun 1985 0.77
107 Prokaryotic adenylate cyclase toxin stimulates anterior pituitary cells in culture. Am J Physiol 1986 0.77
108 "Antigonadal" activity of the neurohypophysial hormones in cultured rat testicular cells: abolition by pertussis toxin. Endocrinology 1984 0.77
109 Oligomeric behavior of Bordetella pertussis adenylate cyclase toxin in solution. Arch Biochem Biophys 2005 0.76
110 Tropical diseases in North America. Dis Mon 1984 0.76
111 Effects of pertussis toxin on cAMP and cGMP responses to carbamylcholine in N1E-115 neuroblastoma cells. Mol Pharmacol 1985 0.76
112 Toxic shock syndrome: clinicopathologic findings in a fatal case. Hum Pathol 1981 0.76
113 ATP shortens atrial action potential duration in the dog: role of adenosine, the vagus nerve, and G protein. Can J Physiol Pharmacol 1996 0.76
114 Acellular pertussis trial. Pediatrics 1996 0.75
115 Protective antibodies in pertussis. J Pediatr 1990 0.75
116 Thyroliberin action in pituitary cells is not inhibited by pertussis toxin. Biochem J 1986 0.75
117 In vivo suppression of delayed hypersensitivity by thiabendazole and diethylcarbamazine. Immunopharmacology 1981 0.75
118 Bacterial adenylate cyclase increases cyclic AMP and hormone release in pituitary tumor cells. Biochem Biophys Res Commun 1986 0.75
119 Pertussis toxin-catalyzed ADP-ribosylation of adenylate cyclase. Effects of guanyl nucleotides and rhodopsin. Dev Biol Stand 1985 0.75
120 Adenylate cyclase in striatal cholinergic interneurons regulates acetylcholine release. Brain Res 1996 0.75
121 Depression of delayed hypersensitivity responses in patients with pertussis. Dev Biol Stand 1985 0.75
122 Detection of Bordetella pertussis by determination of adenylate cyclase activity. Eur J Clin Microbiol Infect Dis 1989 0.75
123 Antiprotozoal activity of tricyclic compounds. Science 1985 0.75
124 Luteinizing hormone secretion is enhanced by pertussis toxin, cholera toxin, and forskolin. Evidence for the involvement of the cyclic AMP-generating system. Neuroendocrinology 1983 0.75
125 Pertussis in adults: significance for disease transmission and immunisation policy. J Med Microbiol 1992 0.75
126 Inhibition of adenylate cyclase from luteinized rat ovary by monovalent cations: roles of the stimulatory guanine nucleotide-binding regulatory component and stimulatory hormone receptor. Arch Biochem Biophys 1988 0.75
127 Dopaminergic inhibition of anterior pituitary adenylate cyclase activity and prolactin release: the effects of perturbing calcium on catalytic adenylate cyclase activity. Neuroendocrinology 1986 0.75