|
1
|
Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis.
|
Gut
|
2005
|
5.39
|
|
2
|
Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors.
|
J Clin Invest
|
1998
|
5.27
|
|
3
|
Extracellular matrix degradation and the role of hepatic stellate cells.
|
Semin Liver Dis
|
2001
|
2.50
|
|
4
|
Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors.
|
J Clin Invest
|
1989
|
2.46
|
|
5
|
Training in academic medicine: a way forward for the new millennium. A discussion document from the Academic Medicine Committee of the Royal College of Physicians.
|
J R Coll Physicians Lond
|
1999
|
2.42
|
|
6
|
Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats.
|
Gastroenterology
|
2001
|
2.25
|
|
7
|
Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors.
|
Gut
|
2001
|
2.02
|
|
8
|
Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis.
|
Hepatology
|
1996
|
1.91
|
|
9
|
Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver.
|
Gastroenterology
|
1996
|
1.79
|
|
10
|
Pathogenesis of liver fibrosis.
|
Clin Sci (Lond)
|
1997
|
1.68
|
|
11
|
Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases-1. Implications for regulation of matrix degradation in liver.
|
J Clin Invest
|
1992
|
1.62
|
|
12
|
Relaxin inhibits effective collagen deposition by cultured hepatic stellate cells and decreases rat liver fibrosis in vivo.
|
Gut
|
2001
|
1.47
|
|
13
|
Corynebacterium parvum-elicited hepatic macrophages demonstrate enhanced respiratory burst activity compared with resident Kupffer cells in the rat.
|
Gastroenterology
|
1986
|
1.37
|
|
14
|
Increased expression of connective tissue growth factor in fibrotic human liver and in activated hepatic stellate cells.
|
J Hepatol
|
2000
|
1.34
|
|
15
|
Macrophage activation, chronic inflammation and gastrointestinal disease.
|
Gut
|
1984
|
1.27
|
|
16
|
Kupffer cells: their activation and role in animal models of liver injury and human liver disease.
|
Semin Liver Dis
|
1993
|
1.19
|
|
17
|
Persistent activation of nuclear factor-kappaB in cultured rat hepatic stellate cells involves the induction of potentially novel Rel-like factors and prolonged changes in the expression of IkappaB family proteins.
|
Hepatology
|
1999
|
1.17
|
|
18
|
Oxygen-derived free radicals promote hepatic injury in the rat.
|
Gastroenterology
|
1985
|
1.17
|
|
19
|
Tissue inhibitor of metalloproteinase-I and interstitial collagenase expression in autoimmune chronic active hepatitis and activated human hepatic lipocytes.
|
Clin Sci (Lond)
|
1995
|
1.17
|
|
20
|
The plasminogen-activating system in hepatic stellate cells.
|
Hepatology
|
1996
|
1.16
|
|
21
|
Progelatinase A is produced and activated by rat hepatic stellate cells and promotes their proliferation.
|
Hepatology
|
1999
|
1.16
|
|
22
|
Human and rat hepatic stellate cells produce stem cell factor: a possible mechanism for mast cell recruitment in liver fibrosis.
|
J Hepatol
|
1999
|
1.16
|
|
23
|
Familial and idiopathic colonic varices: an unusual cause of lower gastrointestinal haemorrhage.
|
Gut
|
1992
|
1.13
|
|
24
|
Pharmacology of propranolol in patients with cirrhosis and portal hypertension.
|
Gut
|
1985
|
1.07
|
|
25
|
Rat hepatic lipocytes synthesize and secrete transin (stromelysin) in early primary culture.
|
Gastroenterology
|
1995
|
1.06
|
|
26
|
JunD regulates transcription of the tissue inhibitor of metalloproteinases-1 and interleukin-6 genes in activated hepatic stellate cells.
|
J Biol Chem
|
2001
|
1.05
|
|
27
|
Primary rat and mouse hepatic stellate cells express the macrophage inhibitor cytokine interleukin-10 during the course of activation In vitro.
|
Hepatology
|
1998
|
1.04
|
|
28
|
Duodenal mucosa synthesis of prostaglandins in duodenal ulcer disease.
|
Gut
|
1985
|
1.04
|
|
29
|
Mechanisms of hepatic fibrosis.
|
J Pediatr Gastroenterol Nutr
|
1998
|
1.03
|
|
30
|
Kupffer cell-derived 95-kd type IV collagenase/gelatinase B: characterization and expression in cultured cells.
|
Hepatology
|
1995
|
1.03
|
|
31
|
Regulation of E-box DNA binding during in vivo and in vitro activation of rat and human hepatic stellate cells.
|
Gut
|
2001
|
1.01
|
|
32
|
Control of the tissue inhibitor of metalloproteinases-1 promoter in culture-activated rat hepatic stellate cells: regulation by activator protein-1 DNA binding proteins.
|
Hepatology
|
1999
|
1.01
|
|
33
|
Upstream tissue inhibitor of metalloproteinases-1 (TIMP-1) element-1, a novel and essential regulatory DNA motif in the human TIMP-1 gene promoter, directly interacts with a 30-kDa nuclear protein.
|
J Biol Chem
|
2000
|
0.92
|
|
34
|
Reduction of ferricytochrome C may underestimate superoxide production by monocytes.
|
J Immunol Methods
|
1987
|
0.92
|
|
35
|
A multicentre randomised trial comparing octreotide and injection sclerotherapy in the management and outcome of acute variceal haemorrhage.
|
Gut
|
1997
|
0.92
|
|
36
|
Hepatitis B, hepatocellular carcinoma, and strategies for prevention.
|
Lancet
|
1984
|
0.90
|
|
37
|
Helicobacter pylori: beware "blind" eradication!
|
Gut
|
1998
|
0.88
|
|
38
|
Differential cellular synthesis of insulin-like growth factor binding protein-1 (IGFBP-1) and IGFBP-3 within human liver.
|
J Clin Endocrinol Metab
|
1994
|
0.87
|
|
39
|
Sex differences in the metabolism of ethanol and acetaldehyde in normal subjects.
|
Clin Sci (Lond)
|
1984
|
0.85
|
|
40
|
Rat hepatic stellate cell expression of alpha2-macroglobulin is a feature of cellular activation: implications for matrix remodelling in hepatic fibrosis.
|
Clin Sci (Lond)
|
1998
|
0.85
|
|
41
|
Hepatocyte-matrix interactions.
|
Gut
|
1994
|
0.84
|
|
42
|
Reversible inhibition of albumin production by rat hepatocytes maintained on a laminin-rich gel (Engelbreth-Holm-Swarm) in response to secretory products of Kupffer cells and cytokines.
|
Hepatology
|
1992
|
0.83
|
|
43
|
Macromolecular aspartate aminotransferase.
|
Eur J Gastroenterol Hepatol
|
1998
|
0.83
|
|
44
|
Effect of gonadotrophin on cell and matrix retention and expression of metalloproteinases and their inhibitor in cultured human granulosa cells modelling corpus luteum function.
|
Mol Hum Reprod
|
1996
|
0.81
|
|
45
|
Matrix degradation in liver: a role in injury and repair.
|
Hepatology
|
1997
|
0.81
|
|
46
|
Augmentation by eosinophils of gelatinase activity in the airway mucosa: comparative effects as a putative mediator of epithelial injury.
|
Br J Pharmacol
|
1996
|
0.77
|
|
47
|
Immunogenetic analysis of a panel of monoclonal IgG and IgM anti-PDC-E2/X antibodies derived from patients with primary biliary cirrhosis.
|
J Hepatol
|
1998
|
0.77
|
|
48
|
The use of a delayed hypersensitivity test and long-acting oxytetracycline in a flock affected with ovine enzootic abortion.
|
Br Vet J
|
1987
|
0.76
|
|
49
|
Mechanisms of liver cell damage and repair.
|
Eur J Gastroenterol Hepatol
|
1999
|
0.76
|
|
50
|
Ovine enzootic abortion: field observations on naturally acquired and vaccine-elicited delayed type hypersensitivity to Chlamydia psittaci (ovis).
|
Vet Rec
|
1986
|
0.75
|
|
51
|
Hyperlactatemia in diabetics with retinopathy during combined sulphonylurea and phenformin therapy.
|
Diabete Metab
|
1978
|
0.75
|
|
52
|
Observations on the effects of monensin on the production of antibodies to coccidia in lambs.
|
Vet Rec
|
1986
|
0.75
|
|
53
|
Pancreatitis in a patient with AIDS.
|
Endoscopy
|
1993
|
0.75
|
|
54
|
Maedi-visna virus infection in commercial flocks of indigenous sheep in Britain.
|
Vet Rec
|
1984
|
0.75
|