Published in J Cell Physiol on September 01, 1985
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Enhanced synthesis of stress proteins caused by hypoxia and relation to altered cell growth and metabolism. Br J Cancer (1990) 1.23
Influence of glucose and oxygen supply conditions on the oxygenation of multicellular spheroids. Br J Cancer (1986) 1.14
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Influence of individual cell motility on the 2D front roughness dynamics of tumour cell colonies. J Biol Phys (2014) 0.77
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Reducing the hypoxic fraction of a tumour model by growth in low glucose. Br J Cancer (1989) 0.77
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A Computational Model for Investigating Tumor Apoptosis Induced by Mesenchymal Stem Cell-Derived Secretome. Comput Math Methods Med (2016) 0.75
Mathematical modelling of spatio-temporal glioma evolution. Theor Biol Med Model (2013) 0.75
A matter of timing: identifying significant multi-dose radiotherapy improvements by numerical simulation and genetic algorithm search. PLoS One (2014) 0.75
Mechanisms of light scattering from biological cells relevant to noninvasive optical-tissue diagnostics. Appl Opt (1998) 3.33
Growth of multicell spheroids in tissue culture as a model of nodular carcinomas. J Natl Cancer Inst (1971) 2.83
Resistance to adriamycin in multicellular spheroids. Int J Radiat Oncol Biol Phys (1979) 2.78
Radiation response of multicell spheroids--an in vitro tumour model. Curr Top Radiat Res Q (1976) 2.73
Selective chemotherapy of noncycling cells in an in vitro tumor model. Cancer Res (1974) 2.44
Cell-associated ovalbumin is cross-presented much more efficiently than soluble ovalbumin in vivo. J Immunol (2001) 2.41
Oxygen in human tumors: correlations between methods of measurement and response to therapy. Summary of a workshop held November 19-20, 1992, at the National Cancer Institute, Bethesda, Maryland. Radiat Res (1993) 1.99
A simple method for obtaining cross-term-free images for diffusion anisotropy studies in NMR microimaging. Magn Reson Med (1991) 1.95
Erythrocyte membrane sulfhydryl groups and cation permeability. J Cell Physiol (1967) 1.83
Light scattering from cells: the contribution of the nucleus and the effects of proliferative status. J Biomed Opt (2000) 1.79
Polarized angular dependent spectroscopy of epithelial cells and epithelial cell nuclei to determine the size scale of scattering structures. J Biomed Opt (2002) 1.78
Variations in tumor cell growth rates and metabolism with oxygen concentration, glucose concentration, and extracellular pH. J Cell Physiol (1992) 1.77
Effects of intercellular contact on repair of radiation damage. Exp Cell Res (1972) 1.76
Regulation of growth saturation and development of necrosis in EMT6/Ro multicellular spheroids by the glucose and oxygen supply. Cancer Res (1986) 1.59
Induction characteristics of oxygen regulated proteins. Int J Radiat Oncol Biol Phys (1986) 1.58
CD8 T cell ignorance or tolerance to islet antigens depends on antigen dose. Proc Natl Acad Sci U S A (1999) 1.55
Requirement for calcium ions in lymphocyte transformation stimulated by phytohemagglutinin. J Cell Physiol (1972) 1.55
Selective dissociation and characterization of cells from different regions of multicell tumor spheroids. Cancer Res (1980) 1.50
Oxygenation and differentiation in multicellular spheroids of human colon carcinoma. Cancer Res (1986) 1.42
Enhanced uptake of calcium by transforming lymphocytes. Cell Immunol (1972) 1.42
The interaction between bleomycin and radiation on cell survival and DNA damage in mammalian cell cultures. Int J Radiat Oncol Biol Phys (1985) 1.36
Glucose diffusivity in multicellular tumor spheroids. Cancer Res (1988) 1.33
Analysis of growth of multicellular tumour spheroids by mathematical models. Cell Prolif (1994) 1.33
In vivo response of KHT sarcomas to combination chemotherapy with radiosensitizers and BCNU. Br J Cancer (1981) 1.32
Oxygen diffusion distance and development of necrosis in multicell spheroids. Radiat Res (1979) 1.28
Evidence of intrinsic differences in the light scattering properties of tumorigenic and nontumorigenic cells. Cancer (1998) 1.28
Letter: Hypoxic radiosensitizers and cellular respiration. Br J Radiol (1976) 1.27
Enhanced synthesis of stress proteins caused by hypoxia and relation to altered cell growth and metabolism. Br J Cancer (1990) 1.23
Activation of metallothionein gene expression by hypoxia involves metal response elements and metal transcription factor-1. Cancer Res (1999) 1.18
Influence of convection in the growth medium on oxygen tensions in multicellular tumor spheroids. Cancer Res (1982) 1.18
In situ oxygen consumption rates of cells in V-79 multicellular spheroids during growth. J Cell Physiol (1984) 1.17
Mathematical modelling of microenvironment and growth in EMT6/Ro multicellular tumour spheroids. Cell Prolif (1992) 1.17
Characterizing Mammalian cells and cell phantoms by polarized backscattering fiber-optic measurements. Appl Opt (2001) 1.15
Influence of glucose and oxygen supply conditions on the oxygenation of multicellular spheroids. Br J Cancer (1986) 1.14
Drug resistance in Chinese hamster ovary cells during recovery from severe hypoxia. J Natl Cancer Inst (1989) 1.11
FTIR spectroscopy demonstrates biochemical differences in mammalian cell cultures at different growth stages. Biophys J (2003) 1.11
Oxygen tensions in multicell spheroids of two cell lines. Br J Cancer (1982) 1.10
31P nuclear magnetic resonance spectroscopy studies of tumor energy metabolism and its relationship to intracapillary oxyhemoglobin saturation status and tumor hypoxia. Cancer Res (1988) 1.09
Mapping of the vascular endothelial growth factor-producing hypoxic cells in multicellular tumor spheroids using a hypoxia-specific marker. Cancer Res (1995) 1.08
The identification of heme oxygenase as a major hypoxic stress protein in Chinese hamster ovary cells. Br J Cancer (1991) 1.08
Growth and cellular characteristics of multicell spheroids. Recent Results Cancer Res (1984) 1.07
Tumor growth in vivo and as multicellular spheroids compared by mathematical models. Bull Math Biol (1994) 1.05
Isolation of quiescent cells from multicellular tumor spheroids using centrifugal elutriation. Cancer Res (1982) 1.04
Hypoxic cells in an in vitro tumour model. Int J Radiat Biol Relat Stud Phys Chem Med (1973) 1.02
Proliferative and clonogenic heterogeneity of cells from EMT6/Ro multicellular spheroids induced by the glucose and oxygen supply. Cancer Res (1986) 1.01
Radiation survival of cells from spheroids grown in different oxygen concentrations. Radiat Res (1979) 1.01
Phytohemagglutinin (PHA)-induced transformation of lymphocytes from patients with cancer. Cancer (1971) 1.00
Misonidazole neurotoxicity in the mouse: evaluation of functional, pharmacokinetic, electrophysiologic and morphologic parameters. Int J Radiat Oncol Biol Phys (1979) 1.00
Hypoxia-induced drug resistance: comparison to P-glycoprotein-associated drug resistance. Br J Cancer (1991) 1.00
Cytokine mediated effects in mucosal immunity. Immunol Cell Biol (1995) 1.00
Assessment of tumor energy and oxygenation status by bioluminescence, nuclear magnetic resonance spectroscopy, and cryospectrophotometry. Cancer Res (1990) 1.00
Misonidazole cytotoxicity in vivo: a comparison of large single doses with smaller doses and extended contact of the drug with tumor cells. Radiat Res (1980) 1.00
Repair of radiation damage to erythrocyte membranes. The reduction of radiation-induced disulfide groups. Radiat Res (1968) 0.99
Optical detection of antibody-antigen reactions at a glass-liquid interface. Clin Chem (1984) 0.99
Differences in growth and morphology between the spontaneous C3H mammary carcinoma in the mouse and its syngeneic transplants. Cancer (1971) 0.99
A multi-component radiation survival curve using an in vitro tumour model. Int J Radiat Biol Relat Stud Phys Chem Med (1970) 0.98
Effect of postoperative radiotherapy on peripheral blood lymphocytes in patients with carcinoma of the breast. Cancer (1972) 0.98
CD4 help-independent induction of cytotoxic CD8 cells to allogeneic P815 tumor cells is absolutely dependent on costimulation. J Immunol (2000) 0.97
Rate of death of hypoxic cells in multicell spheroids. Radiat Res (1978) 0.97
In vivo tumor response to single and multiple exposures of adriamycin. Eur J Cancer (1980) 0.96
Regulation of c-jun expression during hypoxic and low-glucose stress. Mol Cell Biol (1994) 0.96
Nonperturbing test for cytotoxicity in isolated cells and spheroids, using electron paramagnetic resonance. Magn Reson Med (1991) 0.96
Growth of nodular carcinomas in rodents compared with multi-cell spheroids in tissue culture. Growth (1970) 0.96
Evidence for a major role of glucose in controlling development of necrosis in EMT6/Ro multicell tumor spheroids. Adv Exp Med Biol (1983) 0.95
Enhancement of sensitivity of human squamous carcinoma cells to radiation by epidermal growth factor. J Natl Cancer Inst (1989) 0.95
Enhancement of transforming growth factor-alpha synthesis in multicellular tumour spheroids of A431 squamous carcinoma cells. Br J Cancer (1992) 0.95
Neonatal screening for hypothyroidism in Scotland: results of a pilot study. Scott Med J (1981) 0.94
Nitrosourea-misonidazole combination chemotherapy: effect on KHT sarcomas, marrow stem cells and gut. Br J Cancer (1982) 0.94
Enhanced synthesis of specific proteins, RNA, and DNA caused by hypoxia and reoxygenation. Int J Radiat Oncol Biol Phys (1989) 0.94
Cytotoxicity of hypoxic cell sensitizers in multicell spheroids. Cancer Clin Trials (1980) 0.94
In vitro hypoxic cytotoxicity of nitroimidazoles: uptake and cell cycle phase specificity. Int J Radiat Oncol Biol Phys (1982) 0.93
Importance of critical metabolites and cellular interactions in the biology of microregions of tumors. Cancer (1986) 0.93
Differences in EGF related radiosensitisation of human squamous carcinoma cells with high and low numbers of EGF receptors. Br J Cancer (1991) 0.92
Mouse hepatitis virus A59-induced demyelination can occur in the absence of CD8+ T cells. Microb Pathog (1995) 0.92
On the nature of the radiobiologically hypoxic fraction in tumors. Int J Radiat Oncol Biol Phys (1980) 0.92
Adaptation of EGF receptor signal transduction to three-dimensional culture conditions: changes in surface receptor expression and protein tyrosine phosphorylation. J Cell Physiol (1994) 0.92
A comparison of the pharmacokinetics of multiple and single dose administrations of adriamycin. Int J Radiat Oncol Biol Phys (1979) 0.92
Changes in growth characteristics and macromolecular synthesis on recovery from severe hypoxia. Br J Cancer (1990) 0.91
Shedding of mitotic cells from the surface of multicell spheroids during growth. J Cell Physiol (1981) 0.91
Regrowth and radiation sensitivity of quiescent cells isolated from EMT6/Ro-fed plateau monolayers. Cancer Res (1985) 0.91
Multicellular spheroids: a new model target for in vitro studies of immunity to solid tumor allografts. J Natl Cancer Inst (1977) 0.91
Involvement of sulphhydryl groups in radiation damage to the human erythrocyte membrane. Int J Radiat Biol Relat Stud Phys Chem Med (1967) 0.90
Characteristics of calcium accumulation by lymphocytes and alterations in the process induced by phytohemagglutinin. J Cell Physiol (1973) 0.90
Changes in cellular glutathione content during adriamycin treatment in human ovarian cancer--a possible indicator of chemosensitivity. Br J Cancer (1989) 0.90
Selective down-regulation of integrin receptors in spheroids of squamous cell carcinoma. Cancer Res (1994) 0.90
Cryospectrophotometric determination of tumor intravascular oxyhemoglobin saturations: dependence on vascular geometry and tumor growth. J Natl Cancer Inst (1988) 0.89
Mathematical modelling of oxygen supply and oxygenation in tumor tissues: prognostic, therapeutic, and experimental implications. Int J Radiat Oncol Biol Phys (1988) 0.89
Determination of diffusion constants for metabolites in multicell tumor spheroids. Adv Exp Med Biol (1983) 0.89
Effect of duration of breathing 95 percent oxygen plus 5 percent carbon dioxide before x-irradiation on cure of C3H mammary tumor. Cancer (1970) 0.89
The effect of antigen concentration, antibody valency and size, and tumor architecture on antibody binding in multicell spheroids. Int J Rad Appl Instrum B (1991) 0.89
Heterogeneity of glutathione content in human ovarian cancer. Cancer Res (1989) 0.88
Differential regulation of cyclin-dependent kinase inhibitors in monolayer and spheroid cultures of tumorigenic and nontumorigenic fibroblasts. Cancer Res (1998) 0.88