Published in Clin Chem on December 01, 1985
Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia. J Bone Miner Res (1999) 2.50
Mice lacking tissue non-specific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6. Nat Genet (1995) 2.25
Markedly increased circulating pyridoxal-5'-phosphate levels in hypophosphatasia. Alkaline phosphatase acts in vitamin B6 metabolism. J Clin Invest (1985) 1.48
Perinatal hypophosphatasia: tissue levels of vitamin B6 are unremarkable despite markedly increased circulating concentrations of pyridoxal-5'-phosphate. Evidence for an ectoenzyme role for tissue-nonspecific alkaline phosphatase. J Clin Invest (1988) 1.37
Cementum and dentin in hypophosphatasia. J Dent Res (2005) 1.31
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Clearance of uric acid, urea, and creatinine in Down's syndrome. J Appl Physiol (1967) 0.94
Pyridoxine deficiency affects biomechanical properties of chick tibial bone. Bone (1996) 0.93
A versatile cation-exchange procedure of measuring the seven major forms of vitamin B6 in biological samples. Anal Biochem (1983) 0.89
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Human placental vitamin B6 (pyridoxal) transport: normal characteristics and effects of ethanol. Am J Physiol (1992) 0.88
Response of vitamin B-6 content of muscle to changes in vitamin B-6 intake in men. Am J Clin Nutr (1991) 0.87
B6 vitamers: cation exchange HPLC. J Nutr Biochem (1990) 0.87
Microassay of phosphate provides a general method for measuring the activity of phosphatases using physiological, nonchromogenic substrates such as lysophosphatidic acid. Anal Biochem (2001) 0.83
Metabolism of N15 labeled uric acid in Down's syndrome. Metabolism (1968) 0.82
Leukocyte pyridoxal phosphate and alkaline phosphatase in Down's syndrome and other retardates. Am J Clin Nutr (1969) 0.81
Determination of 5-pyridoxic acid, 5-pyridoxic acid lactone, and other vitamin B6 compounds by cation-exchange high-performance liquid chromatography. Methods Enzymol (1997) 0.81
Increased plasma pyridoxal-5'-phosphate levels before and after pyridoxine loading in carriers of perinatal/infantile hypophosphatasia. J Inherit Metab Dis (1990) 0.81
B6 vitamer content of rat tissues measured by isotope tracer and chromatographic methods. Biofactors (1988) 0.81
Effect of megavitamin treatment on mental performance and plasma vitamin B6 concentrations in mentally retarded young adults. Am J Clin Nutr (1983) 0.80
Pyridoxal phosphate in lymphocytes, polymorphonuclear leukocytes, and platelets in Down's syndrome. Am J Clin Nutr (1974) 0.80
Increased serum pyridoxal-5'-phosphate in pseudohypophosphatasia. N Engl J Med (1986) 0.80
Daily rhythm in plasma tyrosine and phenylalanine. Proc Soc Exp Biol Med (1968) 0.79
Adrenocorticotropic hormone increases hydrolysis of B-6 vitamers in swine adrenal glands. J Nutr (1999) 0.78
Connective tissue integrity is lost in vitamin B-6-deficient chicks. J Nutr (1995) 0.78
Metabolism of [14C]- and [32P]pyridoxal 5'-phosphate and [3H]pyridoxal administered intravenously to pigs and goats. J Nutr (1992) 0.78
Human vitamin B-6 pools estimated through muscle biopsies. Am J Clin Nutr (1988) 0.78
Identification of 5'-deoxypyridoxine-3-sulfate as the major urinary metabolite of 5'-deoxypyridoxine in rats with comments on the inhibition of arylsulfatase activity and manganese dioxide oxidation by neighboring groups. Biochem Biophys Res Commun (1978) 0.77
Increased activity of pyridoxal kinase in tongue in Down's syndrome. J Ment Defic Res (1991) 0.77
Elevation of plasma homocysteine in natural menopause can not be explained by a lack of vitamin coenzyme availability: relevance to the risk of cardiovascular disease. J Nutr Health Aging (2005) 0.77
Pyridoxic acid excretion during low vitamin B-6 intake, total fasting, and bed rest. Am J Clin Nutr (1995) 0.77
Low-ultraviolet "white" fluorescent lamps fail to protect pyridoxal phosphate from photolysis. Clin Chem (1987) 0.77
Measurement of vitamin B6 kinetics in vivo using chronic administration of labelled pyridoxine. Prog Clin Biol Res (1984) 0.77
Measurement of the turnover of glycogen phosphorylase by GC/MS using stable isotope derivatives of pyridoxine (vitamin B6). Biochem J (1996) 0.76
Tissue B-6 vitamer concentrations in rats fed excess vitamin B-6. J Nutr (1995) 0.76
Effects of vitamin B-6 deficiency and 4'- deoxypyridoxine on pyridoxal phosphate concentrations, pyridoxine kinase and other aspects of metabolism in the rat. J Nutr (1981) 0.76
Nonprotein nitrogenous metabolites in saliva in Down's syndrome. J Dent Res (1968) 0.76
Standardization of nutritional-status terminology. Am J Clin Nutr (1996) 0.75
Pyridoxal 5'-phosphate transfer in human placenta. Am J Clin Nutr (1997) 0.75
Simplified preparation of a phosphatase inhibitor and further studies of its action. Biochem J (1978) 0.75
Separation of seven B6 vitamers by two-dimensional thin-layer chromatography. Anal Biochem (1977) 0.75
Identification of pyridoxine 3-sulfate, pyridoxal 3-sulfate, and N-methylpyridoxine as major urinary metabolites of vitamin B6 in domestic cats. J Biol Chem (1987) 0.75
An improved method for measuring blood concentrations of phenylpyruvic acid. Clin Chem (1971) 0.75
Non-treatment of defective newborn babies. Lancet (1980) 0.75
Vitamin B-6 content of plasma of domestic animals determined by HPLC, enzymatic and radiometric microbiological methods. J Nutr (1984) 0.75
More on contaminated water purification cartridges. Clin Chem (1983) 0.75
Quantitation of vitamin B6 in biological samples by isotope dilution mass spectrometry. Anal Biochem (1985) 0.75
Tolerances for sample-loop volumes. Clin Chem (1987) 0.75
In vivo metabolism of 4'-deoxypyridoxine in rat and man. J Biol Chem (1976) 0.75
Cardiovascular disease-risk factors in middle-aged osteopaenic women treated with calcium alone or combined to three nutrients essential to artery and bone collagen. J Hum Nutr Diet (2008) 0.75
Effects of B vitamin injections on plasma B vitamin concentrations of feed-restricted beef calves infected with bovine herpesvirus-1. J Anim Sci (1996) 0.75
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Cation-exchange high-performance liquid chromatographic analysis of vitamin B6. Methods Enzymol (1986) 0.75