Published in Lancet on January 16, 1971
Human fecal flora: the normal flora of 20 Japanese-Hawaiians. Appl Microbiol (1974) 20.50
Olive oil, diet and colorectal cancer: an ecological study and a hypothesis. J Epidemiol Community Health (2000) 2.15
Microbes, microbiota, and colon cancer. Cell Host Microbe (2014) 2.06
Carcinogenicity of deoxycholate, a secondary bile acid. Arch Toxicol (2011) 1.92
Dietary fibre. Gut (1973) 1.77
Role of Toll-like receptors in gastrointestinal malignancies. Oncogene (2008) 1.69
Bile acids as endogenous etiologic agents in gastrointestinal cancer. World J Gastroenterol (2009) 1.63
Stool microbiome and metabolome differences between colorectal cancer patients and healthy adults. PLoS One (2013) 1.62
Effects of sulphasalazine (Salazopyrin) on faecal flora in patients with inflammatory bowel disease. Gut (1974) 1.47
The faecal flora of patients with Crohn's disease. J Hyg (Lond) (1981) 1.46
The effect of a chemically defined diet on the faecal flora and faecal steroid concentration. Gut (1973) 1.40
Influence of diets high and low in animal fat on bowel habit, gastrointestinal transit time, fecal microflora, bile acid, and fat excretion. J Clin Invest (1978) 1.32
Extrachromosomal elements in a variety of strains representing the Bacteroides fragilis group of organisms. Infect Immun (1976) 1.31
Dietary fibre and regional large-bowel cancer mortality in Britain. Br J Cancer (1979) 1.24
Gastrointestinal intraluminal pH in normal subjects and those with colorectal adenoma or carcinoma. Gut (1990) 1.22
Colorectal carcinogenesis--update and perspectives. World J Gastroenterol (2014) 1.19
Appendicitis, fibre intake and bowel behaviour in ethnic groups in South Africa. Postgrad Med J (1973) 1.19
High flow oxygen therapy for pneumatosis coli. Gut (1979) 1.18
Benefit and mischief from commensal bacteria. J Clin Pathol (1973) 1.16
Alteration of bile salt metabolism by dietary fibre (bran). Br Med J (1973) 1.13
The faecal flora of children in the United Kingdom. J Hyg (Lond) (1975) 1.09
Occurrence of dysplasia and adenocarcinoma after experimental chronic ulcerative colitis in hamsters induced by dextran sulphate sodium. Gut (1992) 1.08
Faecal bile acids and clostridia in the aetiology of colorectal cancer. Br J Cancer (1980) 1.06
Faecal bile acid concentration of patients with carcinoma or increased risk of carcinoma in the large bowel. Gut (1980) 1.04
Changes of the intestinal microbiota, short chain fatty acids, and fecal pH in patients with colorectal cancer. Dig Dis Sci (2013) 1.02
Colorectal cancer and consumption of beef and fat. Br J Cancer (1975) 1.02
Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis. Clin Exp Gastroenterol (2008) 1.02
The role of the gut flora in the metabolism of cyclamate. Biochem J (1972) 1.01
The normal colonic bacterial flora. Gut (1975) 1.01
Geographic differences in digoxin inactivation, a metabolic activity of the human anaerobic gut flora. Gut (1989) 1.01
Lithocholic acid is an Eph-ephrin ligand interfering with Eph-kinase activation. PLoS One (2011) 1.00
Bile acids: a pH dependent antibacterial system in the gut? Br Med J (1972) 1.00
Metabolism of deoxycorticosterone by human fecal flora. Appl Microbiol (1975) 1.00
Can colonic bacterial metabolites predispose to cholesterol gall stones? Br Med J (1975) 0.99
Digestive disease: the changing scene. Br Med J (1972) 0.98
The high fibre diet in the treatment of diverticular disease of the colon. Postgrad Med J (1974) 0.98
Faecal unconjugated bile acids in patients with colorectal cancer or polyps. Gut (1992) 0.97
Diet and large bowel cancer. J R Soc Med (1990) 0.95
Faecal bacterial flora in cancer of the colon. Gut (1980) 0.94
Increased risk of colorectal cancer after cholecystectomy. Ann Surg (1981) 0.94
Comparison of faecal bile acid profiles between patients with adenomatous polyps of the large bowel and healthy subjects in Japan. Gut (1984) 0.90
Intestinal malignancy and Crohn's disease. Proc R Soc Med (1972) 0.90
Intracolonic environment and the presence of colonic adenomas in man. Gut (1983) 0.89
Intestinal carriage of Bacillus cereus: faecal isolation studies in three population groups. J Hyg (Lond) (1985) 0.87
Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity. BMC Cancer (2006) 0.86
Faecal bile acid profiles in patients with large bowel cancer in Japan. Gut (1984) 0.86
Fecal primary bile acids and serum cholesterol are associated with colorectal adenomas. Dig Dis Sci (2003) 0.85
Bile, bacteria and bowel cancer. Gut (1983) 0.84
Faecal bile acid excretion in children with inflammatory bowel disease. Gut (1991) 0.84
Gut microbiome compositional and functional differences between tumor and non-tumor adjacent tissues from cohorts from the US and Spain. Gut Microbes (2015) 0.83
Increased risk of colorectal cancer following breast cancer. Ann Surg (1986) 0.83
Dietary fibre and colon cancer: epidemiologic and experimental evidence. Can Med Assoc J (1980) 0.83
The cocarcinogenic effect of intrarectal deoxycholate in rats is reduced by oral metronidazole. Br J Cancer (1984) 0.82
Regulation of deoxycholate induction of CXCL8 by the adenomatous polyposis coli gene in colorectal cancer. Int J Cancer (2009) 0.82
Fat and cancer. Br Med J (Clin Res Ed) (1983) 0.81
Diet and nutrition. Bull N Y Acad Med (1978) 0.80
Colorectal cancer drug target prediction using ontology-based inference and network analysis. Database (Oxford) (2015) 0.79
Faecal bile acids and clostridia in patients with breast cancer. Br J Cancer (1980) 0.79
Biliary bile acids in cholelithiasis and colon cancer. Gut (1989) 0.79
Microbial biofilms and gastrointestinal diseases. Pathog Dis (2013) 0.79
Evidence for the mixing of residue in the human gut. Gut (1976) 0.78
Microbiota and immune responses in colon cancer: more to learn. Cancer J (2014) 0.77
Sporadic colorectal cancer: microbial contributors to disease prevention, development and therapy. Br J Cancer (2016) 0.77
Lifestyle and colorectal cancer: A case-control study. Environ Health Prev Med (1998) 0.77
Disaccharidase deficiency in health and disease. Calif Med (1972) 0.76
Relative carriage rates of nuclear dehydrogenating clostridia in two populations of different colorectal cancer risk. J Clin Pathol (1983) 0.76
Fibre and cancer of the colon. Br J Cancer (1973) 0.76
Experimental colonic carcinogenesis: changes in faecal bile acids after promotion of intestinal tumours by small bowel resection in the rat. Gut (1988) 0.76
Carcinoma of the colon and rectum. A perspective for practicing physicians, with recommendations for screening. West J Med (1977) 0.75
Intestinal disease and the urban environment. Environ Health Perspect (1979) 0.75
Editorial: faecal fibre fortunes. Br Med J (1975) 0.75
Editorial: Diet and colonic cancer. Br Med J (1974) 0.75
The conversion of cyclamate into cyclohexylamine by gut bacteria. Biochem J (1971) 0.75
The effect of changes in the environment on the health of the community--an epidemiologist's view. J R Coll Gen Pract (1975) 0.75
Relation between intragastric bile acid concentration and mucosal abnormality in the stomach after vagotomy and gastroenterostomy for duodenal ulcer. J Clin Pathol (1984) 0.75
Aromatization of androst-4-ene-3,17-dione by human intestinal bacteria. Biochem J (1971) 0.75
The etiological significance of related diseases. Can Fam Physician (1976) 0.75
Bacterial challenges in food. Postgrad Med J (1974) 0.75
Cancer research: preparing for a long haul. Br Med J (1972) 0.75
Microbial species involved in production of 1,2-sn-diacylglycerol and effects of phosphatidylcholine on human fecal microbiota. Appl Environ Microbiol (2004) 0.75
Food systems: the relationship between health and food science/technology. Environ Health Perspect (1990) 0.75
The relationship between stool weight and the lithocholate/deoxycholate ratio in faeces. Br J Cancer (1988) 0.75
Mechanisms of pathogenicity of anaerobic bacteria of clinical interest. Infection (1980) 0.75
Cultivation of anaerobic intestinal bacteria. J Pathol Bacteriol (1967) 8.83
Studies on the intestinal flora. I. The bacterial flora of the gastrointestinal tract in healthy and achlorhydric persons. Gastroenterology (1969) 5.43
T-strain mycoplasma in non-gonococcal urethritis. Lancet (1966) 5.16
Overexpression of the maize homeo box gene, KNOTTED-1, causes a switch from determinate to indeterminate cell fates. Genes Dev (1993) 3.77
Bacteria and the aetiology of cancer of the large bowel. Gut (1969) 3.57
Detection of Brucella melitensis and Brucella abortus by DNA amplification. J Trop Med Hyg (1992) 3.32
Degradation of bile salts by human intestinal bacteria. Gut (1968) 3.15
Action of bile salts on bacterial cell walls. Nature (1967) 2.68
Transport and storage of faeces for bacteriological examination. J Appl Bacteriol (1971) 2.59
Aetiology of adenoma--carcinoma sequence in large bowel. Lancet (1978) 2.52
The cell walls of streptococci. J Gen Microbiol (1965) 2.42
Obligatory role of gamma interferon for host survival in a murine model of infection with Burkholderia pseudomallei. Infect Immun (1999) 2.41
Bacteria and the N-nitrosation of secondary amines. Br J Cancer (1971) 2.41
Faecal bile-acids and clostridia in patients with cancer of the large bowel. Lancet (1975) 2.40
Environmental factors and cancer of the colon and breast. Br J Cancer (1973) 2.36
Gut bacteria and aetiology of cancer of the breast. Lancet (1971) 2.29
Phage typing of staphylococci. Bull World Health Organ (1961) 2.23
Mortality from gastric cancer following gastric surgery for peptic ulcer. Lancet (1986) 2.23
Effect of cimetidine on the gastric bacterial flora. Lancet (1980) 2.18
Degradation of steroids by intestinal bacteria. II. Enzymes catalysing the oxidoreduction of the 3 alpha-, 7 alpha- and 12 alpha-hydroxyl groups in cholic acid, and the dehydroxylation of the 7-hydroxyl group. Biochim Biophys Acta (1970) 2.13
Response of toxigenic Vibrio cholerae 01 to physico-chemical stresses in aquatic environments. J Hyg (Lond) (1984) 2.12
Effects of Burkholderia pseudomallei and other Burkholderia species on eukaryotic cells in tissue culture. Microbios (1998) 2.11
Studies of the effectiveness of an isolation ward. J Hyg (Lond) (1969) 2.10
Breath-hydrogen test for small-intestinal bacterial colonisation. Lancet (1976) 2.09
Increased risk of cancer at multiple sites after gastric surgery for peptic ulcer. Gut (1987) 2.08
The deconjugation of bile salts by human intestinal bacteria. Lancet (1966) 2.06
The effect of meat protein and dietary fiber on colonic function and metabolism. II. Bacterial metabolites in feces and urine. Am J Clin Nutr (1979) 2.06
The aquatic flora and fauna as reservoirs of Vibrio cholerae: a review. J Diarrhoeal Dis Res (1994) 2.04
Effects of high-probability requests on the acquisition and generalization of responses to requests in young children with behavior disorders. J Appl Behav Anal (1992) 2.03
Dietary salt, nitrate and stomach cancer mortality in 24 countries. European Cancer Prevention (ECP) and the INTERSALT Cooperative Research Group. Int J Epidemiol (1996) 1.99
Antibiotic resistance of coagulase-negative staphylococci and micrococci. J Clin Pathol (1968) 1.91
Endothelium-dependent vasodilation is attenuated in patients with heart failure. Circulation (1991) 1.91
Changes in fecal composition and colonic function due to cereal fiber. Am J Clin Nutr (1976) 1.91
The association between typhoid carriage, typhoid infection and subsequent cancer at a number of sites. Eur J Cancer Prev (1995) 1.89
Antibacterial antibodies in rectal and colonic mucosa in ulcerative colitis. Lancet (1971) 1.88
The impact of gunshot wounds on an orthopaedic surgical service in an urban trauma center. J Orthop Trauma (1997) 1.87
Bacteria, nitrosamines and cancer of the stomach. Br J Cancer (1973) 1.83
Intestinal bacteria and the hydrolysis of glycosidic bonds. J Med Microbiol (1971) 1.73
The non-sporing anaerobic bacteria in human faeces. J Med Microbiol (1974) 1.68
De motu urbanorum. Br Med J (1975) 1.67
Degradation of bile salts by human intestinal bacteria. Gut (1969) 1.66
Long-term persistence of toxigenic Vibrio cholerae 01 in the mucilaginous sheath of a blue-green alga, Anabaena variabilis. J Trop Med Hyg (1990) 1.62
Gastric-juice nitrite. A risk factor for cancer in the hypochlorhydric stomach? Lancet (1976) 1.61
Intragastric nitrites, nitrosamines, and bacterial overgrowth during cimetidine treatment. Gut (1982) 1.60
Phage typing of coagulase-negative staphylococci and micrococci. J Hyg (Lond) (1973) 1.59
Clostridia isolated from faeces. J Med Microbiol (1976) 1.58
Nasal acquisition of Staphylococcus aureus in partly divided wards. J Hyg (Lond) (1971) 1.57
Pathogenesis of gastric cancer in pernicious anaemia. Lancet (1978) 1.57
Cost of treating an infected total knee replacement. Clin Orthop Relat Res (1996) 1.56
Thermal comfort during surgical operations. J Hyg (Lond) (1968) 1.56
Water supply and nutritional status in rural northern Nigeria. Trans R Soc Trop Med Hyg (1978) 1.54
Biliary bile acid profiles in familial adenomatous polyposis. Br J Surg (1991) 1.54
Studies on the intestinal flora. II. Bacterial flora of the small intestine in patients with gastrointestinal disorders. Gut (1969) 1.53
Ribotyping and DNA macrorestriction analysis of isolates of Burkholderia pseudomallei from cases of melioidosis in Malaysia. Trans R Soc Trop Med Hyg (1997) 1.52
Cholera epidemiology in developed and developing countries: new thoughts on transmission, seasonality, and control. Lancet (1985) 1.51
Electrically-heated inoculating loop. J Clin Pathol (1968) 1.51
Attachment of toxigenic Vibrio cholerae 01 to various freshwater plants and survival with a filamentous green alga, Rhizoclonium fontanum. J Trop Med Hyg (1989) 1.49
Colon cancer: a disease of fibre depletion or of dietary excess? Digestion (1974) 1.48
Effects of sulphasalazine (Salazopyrin) on faecal flora in patients with inflammatory bowel disease. Gut (1974) 1.47
Alienation, self-esteem and attitudes toward drinking in high-school students. Q J Stud Alcohol (1968) 1.42
Analyses of DNA content, nuclear size and cell proliferation of transitional cell carcinoma in man. Cancer (1969) 1.41
Effect of feeding on infants' faecal flora. Arch Dis Child (1982) 1.41
Mutations in the palmitoyl-protein thioesterase gene (PPT; CLN1) causing juvenile neuronal ceroid lipofuscinosis with granular osmiophilic deposits. Hum Mol Genet (1998) 1.41
Bacterial colonisation of jejunal mucosa in acute tropical sprue. Lancet (1975) 1.41
The effect of a chemically defined diet on the faecal flora and faecal steroid concentration. Gut (1973) 1.40
Primary prevention of colorectal cancer. The WHO Collaborating Centre for the Prevention of Colorectal Cancer. Bull World Health Organ (1990) 1.40
Diploma in Hospital Infection Control (Dip HIC) J Hosp Infect (1997) 1.39
The effect of prostatectomy on symptom severity and quality of life. Br J Urol (1996) 1.39
Faecal steroid composition and its relationship to cancer of the large bowel. J Pathol (1971) 1.36
Characterization of the human granulocyte-macrophage colony-stimulating factor receptor. J Biol Chem (1988) 1.35
Influence of diets high and low in animal fat on bowel habit, gastrointestinal transit time, fecal microflora, bile acid, and fat excretion. J Clin Invest (1978) 1.32
IL-12 induces human T cells secreting IL-10 with IFN-gamma. J Immunol (1996) 1.32
Control of Meloidogyne chitwoodi in Potato with Fumigant and Nonfumigant Nematicides. J Nematol (2000) 1.32
Warburg revisited: imaging tumour blood flow and metabolism. Cancer Imaging (2008) 1.31
The serum opacity reaction of Streptococcus pyogenes: general properties of the streptococcal factor and of the reaction in aged serum. J Hyg (Lond) (1968) 1.30
Effects of high-probability requests on the social interactions of young children with severe disabilities. J Appl Behav Anal (1994) 1.29
The aquatic environment as a reservoir of Vibrio cholerae: a review. J Diarrhoeal Dis Res (1993) 1.28
Bridging scientist and practitioner perspectives in clinical psychology. Am Psychol (1995) 1.26
The role of colon anaerobes in the metabolism of bile acids and steroids, and its relation to colon cancer. Cancer (1975) 1.26
Association of Vibrio cholerae with fresh water amoebae. J Med Microbiol (1992) 1.26
The digestion of pectin in the human gut and its effect on calcium absorption and large bowel function. Br J Nutr (1979) 1.25