Biochemical properties of histocompatibility antigens.

PubWeight™: 1.38‹?› | Rank: Top 10%

🔗 View Article (PMID 4136564)

Published in Annu Rev Genet on January 01, 1970

Authors

S G Nathenson

Articles by these authors

(truncated to the top 100)

Isolation of an endogenously processed immunodominant viral peptide from the class I H-2Kb molecule. Nature (1990) 6.59

Mitotic recombination in germ cells generated two major histocompatibility complex mutant genes shown to be identical by RNA sequence analysis: Kbm9 and Kbm6. Proc Natl Acad Sci U S A (1986) 3.15

Primary structural: analysis of the transplantation antigens of the murine H-2 major histocompatibility complex. Annu Rev Biochem (1981) 2.93

Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex. Nat Immunol (2001) 2.83

Spontaneous H-2 mutants provide evidence that a copy mechanism analogous to gene conversion generates polymorphism in the major histocompatibility complex. Proc Natl Acad Sci U S A (1983) 2.51

Biochemistry of the gene products from murine MHC mutants. Annu Rev Genet (1980) 2.49

Primary structure of a murine transplantation antigen. Nature (1981) 2.42

Structural and serological properties of murine Ia alloantigens. Transplant Rev (1976) 2.35

Solubilization and partial purification of mouse histocompatibility antigens from a membranous lipoprotein fraction. Proc Natl Acad Sci U S A (1966) 2.33

Murine major histocompatibility complex class-I mutants: molecular analysis and structure-function implications. Annu Rev Immunol (1986) 2.29

Isolation of H-2 alloantigens solubilized by the detergent NP-40. J Immunol (1971) 2.26

Structural basis for co-stimulation by the human CTLA-4/B7-2 complex. Nature (2001) 2.21

Membrane molecules determined by the H-2 associated immune response region: isolation and some properties. Proc Natl Acad Sci U S A (1974) 2.17

Crystal structure of the major histocompatibility complex class I H-2Kb molecule containing a single viral peptide: implications for peptide binding and T-cell receptor recognition. Proc Natl Acad Sci U S A (1992) 2.16

Murine histocompatibility-2 (H-2) alloantigens. Purification and some chemical properties of soluble products from H-2b and H-2d genotypes released by papain digestion of membrane fractions. Biochemistry (1969) 2.06

Comparison of the cloned H-2Kbm1 variant gene with the H-2Kb gene shows a cluster of seven nucleotide differences. Proc Natl Acad Sci U S A (1983) 1.92

Biochemical properties and immunochemical-genetic relationships of mouse H-2 alloantigens. Biochim Biophys Acta (1974) 1.91

The three-dimensional structure of H-2Db at 2.4 A resolution: implications for antigen-determinant selection. Cell (1994) 1.90

Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement. Proc Natl Acad Sci U S A (1998) 1.82

The genome-linked protein of picornaviruses. VII. Genetic mapping of poliovirus VPg by protein and RNA sequence studies. Cell (1980) 1.80

Evidence that multiple residues on both the alpha-helices of the class I MHC molecule are simultaneously recognized by the T cell receptor. Cell (1988) 1.77

Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions. J Immunol (2000) 1.77

Atomic structure of an alphabeta T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody. EMBO J (1998) 1.74

Notable diversity in peptide composition of murine H-2K and H-2D alloantigens. Biochemistry (1974) 1.70

The distribution of alloantigenic specificities of native H-2 products. J Immunol (1972) 1.69

H-2 histocompatibility alloantigens. Some biochemical properties of the molecules solubilized by NP-40 detergent. Biochemistry (1973) 1.68

Regeneration of transplantation antigens on mouse cells. Transplant Proc (1971) 1.56

Interaction between Kb and Q4 gene sequences generates the Kbm6 mutation. Mol Cell Biol (1986) 1.50

Mature T cell reactivity altered by peptide agonist that induces positive selection. J Exp Med (1996) 1.50

Suppression of immunoglobulin synthesis by cellular hybridization. Nat New Biol (1971) 1.50

Structural differences between parent and mutant H-2K glycoproteins from two H-2K gene mutants: b6.c-h-2ba (Hzl) and B6-H-2bd (M505). J Immunol (1977) 1.48

Identification of the cloned gene for the murine transplantation antigen H-2Kb by hybridization with synthetic oligonucleotides. Mol Cell Biol (1983) 1.48

The structure of the antigen-binding groove of major histocompatibility complex class I molecules determines specific selection of self-peptides. Proc Natl Acad Sci U S A (1991) 1.47

Structure of murine CTLA-4 and its role in modulating T cell responsiveness. Science (2000) 1.45

A general method for facilitating heterodimeric pairing between two proteins: application to expression of alpha and beta T-cell receptor extracellular segments. Proc Natl Acad Sci U S A (1994) 1.44

Solubilization of membrane H-2 isoantigens: chromatographic separation of specificities determined by a single H-2 genotype. Biochem Biophys Res Commun (1967) 1.42

Intramolecular organization of Class I H-2 MHC antigens; localization of the alloantigenic determinants and the beta 2 m binding site to different regions of the H-2 Kb glycoprotein. J Immunol (1983) 1.41

Mapping class I gene sequences in the major histocompatibility complex. Nature (1982) 1.35

Cell-surface glycopeptides: growth-dependent changes in the carbohydrate-peptide linkage region. J Mol Biol (1973) 1.29

Enzymatic synthesis and immunochemistry of alpha- and beta-N-acetylglucosaminylribitol linkages in teichoic acids from several strains of Staphylococcus aureus. J Biol Chem (1966) 1.28

Localization of the papain cleavage site of H-2 glycoproteins. Proc Natl Acad Sci U S A (1976) 1.28

Vesicular stomatitis virus antigenic octapeptide N52-59 is anchored into the groove of the H-2Kb molecule by the side chains of three amino acids and the main-chain atoms of the amino terminus. Proc Natl Acad Sci U S A (1992) 1.28

Three distinct signals can induce class II gene expression in a murine pre-B-cell line. Proc Natl Acad Sci U S A (1986) 1.22

Structural comparisons of TL antigens derived from normal and leukemia cells of Tl+ and TL- strains and relationship to genetically linked H-2 major histocompatibility complex products. Proc Natl Acad Sci U S A (1981) 1.19

Solubilization of human leucocyte membrane isoantigens. Nature (1968) 1.16

Studies on the carbohydrate portion of membrane-located mouse H-2 alloantigens. Biochemistry (1970) 1.15

Primary structural studies of an H-2L molecule confirm that it is a unique gene product with homology to H-2K and H-2D antigens. Proc Natl Acad Sci U S A (1980) 1.14

A nonpolymorphic major histocompatibility complex class Ib molecule binds a large array of diverse self-peptides. J Exp Med (1994) 1.14

The molecular basis of codominant expression of the histocompatibility-2 genetic region. Proc Natl Acad Sci U S A (1972) 1.13

Evidence that the antigen receptors of cytotoxic T lymphocytes interact with a common recognition pattern on the H-2Kb molecule. Immunity (1995) 1.12

Identification of a common docking topology with substantial variation among different TCR-peptide-MHC complexes. Curr Biol (1998) 1.11

Three spontaneous H-2Db mutants are generated by genetic micro-recombination (gene conversion) events. Impact on the H-2-restricted immune responsiveness. J Exp Med (1988) 1.08

Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool. Diabetes (2001) 1.07

Conservation and diversity in the class I genes of the major histocompatibility complex: sequence analysis of a Tlab gene and comparison with a Tlac gene. Proc Natl Acad Sci U S A (1986) 1.05

Primary structure of murine major histocompatibility complex alloantigens: amino acid sequence of the amino-terminal one hundred and seventy-three residues of the H-2Kb glycoprotein. Biochemistry (1980) 1.05

Cell surface antigen induced by Friend murine leukemia virus is also in the virion. J Virol (1974) 1.03

Further structural analysis of the murine H-2Kb glycoprotein using radiochemical methodology. Mol Immunol (1979) 1.03

Primary structure of murine major histocompatibility complex alloantigens: isolation, biochemical characterization, and preliminary alignment of CNBr fragments from the H-2Ib glycoprotein. Proc Natl Acad Sci U S A (1978) 1.01

Comparison of soluble human and mouse transplantation antigens. Proc Natl Acad Sci U S A (1969) 1.01

Analysis of somatic cell H-2 variants to define the structural requirements for class I antigen expression. J Immunol (1986) 1.00

Studies on the FMR antigen. Transplant Proc (1969) 0.99

Primary structure of murine major histocompatibility complex alloantigens: amino acid sequence studies of the cyanogen bromide fragments of the H-2Kb glycoprotein. Proc Natl Acad Sci U S A (1978) 0.99

The three-dimensional structure of an H-2Ld-peptide complex explains the unique interaction of Ld with beta-2 microglobulin and peptide. Proc Natl Acad Sci U S A (1997) 0.99

Crystallization of a deglycosylated T cell receptor (TCR) complexed with an anti-TCR Fab fragment. J Biol Chem (1996) 0.98

Intracellular transport of class I histocompatibility molecules. Influence of protein folding on transport to the cell surface. J Biol Chem (1988) 0.97

Isolation, characterization and amino acid sequence studies of the cyanogen bromide fragments of the H-2Dd glycoprotein. Eur J Immunol (1980) 0.96

Methods to study peptides associated with MHC class I molecules. Curr Opin Immunol (1994) 0.96

Biochemical studies on the H-2K antigens of the MHC mutant bml. Immunogenetics (1981) 0.96

Characterization of an incompletely assembled major histocompatibility class I molecule (H-2Kb) associated with unusually long peptides: implications for antigen processing and presentation. Proc Natl Acad Sci U S A (1994) 0.95

Direct demonstration that cytotoxic T lymphocytes recognize conformational determinants and not primary amino acid sequences. J Exp Med (1983) 0.94

Microrecombinations generate sequence diversity in the murine major histocompatibility complex: analysis of the Kbm3, Kbm4, Kbm10, and Kbm11 mutants. Mol Cell Biol (1988) 0.94

Diversity of T cell receptors specific for the VSV antigenic peptide (N52-59) bound by the H-2Kb class I molecule. Cell Immunol (1995) 0.94

Altered peptide ligand-mediated TCR antagonism can be modulated by a change in a single amino acid residue within the CDR3 beta of an MHC class I-restricted TCR. J Immunol (2000) 0.94

Binding of longer peptides to the H-2Kb heterodimer is restricted to peptides extended at their C terminus: refinement of the inherent MHC class I peptide binding criteria. J Immunol (1999) 0.93

Some biochemical properties of thymus leukemia antigens solubilized from cell membranes by papain digestion. J Exp Med (1973) 0.92

Molecular recognition of human CD1b antigen complexes: evidence for a common pattern of interaction with alpha beta TCRs. J Immunol (2000) 0.92

A simplified procedure for the preparation of MHC/peptide tetramers: chemical biotinylation of an unpaired cysteine engineered at the C-terminus of MHC-I. J Immunol Methods (2000) 0.91

Structural studies on H-2Db and H-2Kd molecules indicate that murine major histocompatibility b and d haplotype alloantigens share structural features. Mol Immunol (1980) 0.91

Analysis of associative recognition determinants on class I H-2Kb mutant molecules. Immunogenetics (1985) 0.91

Amino acid sequence of residues 1-98 of the K-2Kb murine major histocompatibility alloantigen: comparison with H-2Kb and H-2db reveals extensive localized differences. Biochemistry (1981) 0.91

Distribution of H-2 alloantigenic specificities on radiolabeled papain-solubilized antigen fragments. J Immunol (1971) 0.91

The role of self peptides in the allogeneic cross-reactivity of CTLs. J Immunol (1995) 0.91

Murine histocompatibility-2 (H-2) alloantigens. Purification and some chemical properties of a second class of fragments (class II) solubilized by papain from cell membranes of H-2b and H-2d mice. Biochemistry (1970) 0.91

Abnormalities in the glycosylation of immunoglobulin heavy chain and an h-2 transplantation antigen in a mouse myeloma mutant. Cell (1977) 0.90

Structural studies of class I major histocompatibility complex proteins: insights into antigen presentation. FASEB J (1995) 0.90

Primary structure of murine major histocompatibility complex alloantigens. Amino acid sequence of the NH2-terminal ninety-eight residues of the H-2Db glycoprotein. J Biol Chem (1981) 0.90

Point mutations in the beta chain CDR3 can alter the T cell receptor recognition pattern on an MHC class I/peptide complex over a broad interface area. Mol Immunol (1998) 0.90

Amino acid sequence of the carboxyl-terminal hydrophilic region of the H-2Kb MHC alloantigen. Completion of the entire primary structure of the H-2Kb molecule. Biochemistry (1981) 0.89

Amino acid sequence of cyanogen bromide fragment CN-C (residues 24-98) of the mouse histocompatibility antigen H-2Dd. A comparison of the amino-terminal 100 residues of H-2Dd, Dd, Kd, and Kb reveals discrete areas of diversity. Biochemistry (1981) 0.89

Selective loss of H-2 antigenic reactivity after chemical modification. J Immunol (1973) 0.89

Biochemical studies of H-2K antigens from a group of related mutants. II. Identification of a shared mutation in B6-H-2bm6, B6.C-H-2bm7, and B6.C-H-2bm9. Immunogenetics (1983) 0.88

Biochemical similarity of papain-solubilized H-2d alloantigens from tumor cells and from normal cells. Biochemistry (1970) 0.88

Structure of murine major histocompatibility complex alloantigens: identification of cysteine residues involved in two intrachain disulfide bonds of H-2K. Mol Immunol (1981) 0.88

Topology of T cell receptor-peptide/class I MHC interaction defined by charge reversal complementation and functional analysis. J Mol Biol (1997) 0.87

Comparison of alloantisera and hybridoma antibody for purification of the H-2Db murine histocompatibility antigen and preliminary molecular characterization of this antigen. J Immunol Methods (1980) 0.87

Secondary structure of the murine histocompatibility alloantigen H-2Kb: relationship between heavy chain, beta 2-microglobulin, and antigenic reactivity. Biochemistry (1985) 0.87

Molecular heterogeneity of human lymphoid (HL-A) alloantigens. Science (1969) 0.86

Structural evidence that the small subunit found associated with the TL antigen is beta 2-microglobulin. Immunogenetics (1982) 0.86

Isolation of a chromatographically unique glycopeptide from murine histocompatibility-2 (H-2) membrane alloantigens labelled with H3-fucose of H3-glucosamine. Biochem Biophys Res Commun (1970) 0.86

Immunogenic properties of papain-solubilized alloantigen. Transplant Proc (1971) 0.86