PubRank

J A Hoch

Author PubWeight™ 247.11‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Initiation of sporulation in B. subtilis is controlled by a multicomponent phosphorelay. Cell 1991 9.53
2 Construction and properties of an integrable plasmid for Bacillus subtilis. J Bacteriol 1983 7.12
3 Transformation and transduction in recombination-defective mutants of Bacillus subtilis. J Bacteriol 1967 6.62
4 Structure of the gene for the transition state regulator, abrB: regulator synthesis is controlled by the spo0A sporulation gene in Bacillus subtilis. Mol Microbiol 1988 5.20
5 Characterization of the spo0A locus and its deduced product. Proc Natl Acad Sci U S A 1985 4.86
6 Revised genetic linkage map of Bacillus subtilis. Microbiol Rev 1985 4.40
7 The Bacillus subtilis chromosome. Microbiol Rev 1980 4.37
8 The SpoOA protein of Bacillus subtilis is a repressor of the abrB gene. Proc Natl Acad Sci U S A 1990 4.24
9 Characterization of the gene for a protein kinase which phosphorylates the sporulation-regulatory proteins Spo0A and Spo0F of Bacillus subtilis. J Bacteriol 1989 4.20
10 Genetics of bacterial sporulation. Adv Genet 1976 4.05
11 The oligopeptide transport system of Bacillus subtilis plays a role in the initiation of sporulation. Mol Microbiol 1991 3.93
12 Deduced product of the stage 0 sporulation gene spo0F shares homology with the Spo0A, OmpR, and SfrA proteins. Proc Natl Acad Sci U S A 1985 3.60
13 Mapping a cloned gene under sporulation control by inserttion of a drug resistance marker into the Bacillus subtilis chromosome. J Bacteriol 1980 3.49
14 A two-component signal transduction system essential for growth of Bacillus subtilis: implications for anti-infective therapy. J Bacteriol 1998 3.47
15 Two-component signal transduction in Bacillus subtilis: how one organism sees its world. J Bacteriol 1999 3.42
16 The transition state transcription regulator abrB of Bacillus subtilis is a DNA binding protein. EMBO J 1989 3.31
17 Multiple histidine kinases regulate entry into stationary phase and sporulation in Bacillus subtilis. Mol Microbiol 2000 3.25
18 Multiple protein-aspartate phosphatases provide a mechanism for the integration of diverse signals in the control of development in B. subtilis. Cell 1994 3.22
19 Transcription of Bacillus subtilis subtilisin and expression of subtilisin in sporulation mutants. J Bacteriol 1988 3.20
20 Genetic analysis of a class of polymyxin resistant partial revertants of stage O sporulation mutants of Bacillus subtilis: map of the chromosome region near the origin of replication. Mol Gen Genet 1979 3.03
21 Identification of the transcriptional suppressor sof-1 as an alteration in the spo0A protein. J Bacteriol 1985 2.89
22 Citric acid cycle: gene-enzyme relationships in Bacillus subtilis. J Bacteriol 1970 2.86
23 Chromosomal location of a Bacillus subtilis DNA fragment uniquely transcribed by sigma-28-containing RNA polymerase. J Bacteriol 1982 2.82
24 Cell-cell communication regulates the effects of protein aspartate phosphatases on the phosphorelay controlling development in Bacillus subtilis. Proc Natl Acad Sci U S A 1996 2.75
25 Cloning structural gene sacB, which codes for exoenzyme levansucrase of Bacillus subtilis: expression of the gene in Escherichia coli. J Bacteriol 1983 2.73
26 A transient interaction between two phosphorelay proteins trapped in a crystal lattice reveals the mechanism of molecular recognition and phosphotransfer in signal transduction. Structure 2000 2.71
27 Genetic analysis of pleiotropic negative sporulation mutants in Bacillus subtilis. J Bacteriol 1971 2.61
28 Transition-state regulators: sentinels of Bacillus subtilis post-exponential gene expression. Mol Microbiol 1993 2.60
29 Genetic analysis in Bacillus subtilis. Methods Enzymol 1991 2.56
30 Multisensory activation of the phosphorelay initiating sporulation in Bacillus subtilis: identification and sequence of the protein kinase of the alternate pathway. Mol Microbiol 1993 2.54
31 Alteration of the Bacillus subtilis glutamine synthetase results in overproduction of the enzyme. J Bacteriol 1977 2.49
32 Isolation of Bacillus subtilis genes from a charon 4A library. J Bacteriol 1981 2.45
33 Chromosomal location and properties of radiation sensitivity mutations in Bacillus subtilis. J Bacteriol 1970 2.44
34 Phenotypes of pleiotropic-negative sporulation mutants of Bacillus subtilis. J Bacteriol 1973 2.42
35 Sequence analysis and regulation of the hpr locus, a regulatory gene for protease production and sporulation in Bacillus subtilis. J Bacteriol 1988 2.39
36 Effect of stage 0 sporulation mutations on subtilisin expression. J Bacteriol 1986 2.31
37 Hyperprotease-producing mutants of Bacillus subtilis. J Bacteriol 1972 2.29
38 Sequence analysis of the spo0B locus reveals a polycistronic transcription unit. J Bacteriol 1985 2.28
39 Deactivation of the sporulation transcription factor Spo0A by the Spo0E protein phosphatase. Proc Natl Acad Sci U S A 1994 2.24
40 The Bacillus subtilis spo0B stage 0 sporulation operon encodes an essential GTP-binding protein. J Bacteriol 1989 2.21
41 Two-component signal transduction as a target for microbial anti-infective therapy. Antimicrob Agents Chemother 1998 2.17
42 Chromosomal location of pleiotropic negative sporulation mutations in Bacillus subtilis. Genetics 1973 1.99
43 Isolation and sequence of the spo0E gene: its role in initiation of sporulation in Bacillus subtilis. Mol Microbiol 1987 1.99
44 Complete sequence and transcriptional analysis of the spo0F region of the Bacillus subtilis chromosome. J Bacteriol 1988 1.91
45 Mechanism of transfection with deoxyribonucleic acid from the temperate Bacillus bacteriophage phi-105. J Virol 1969 1.90
46 Molecular recognition in signal transduction: the interaction surfaces of the Spo0F response regulator with its cognate phosphorelay proteins revealed by alanine scanning mutagenesis. J Mol Biol 1997 1.86
47 Spo0A activates and represses its own synthesis by binding at its dual promoters. Biochimie 1992 1.82
48 Synergistic kinetic interactions between components of the phosphorelay controlling sporulation in Bacillus subtilis. Biochemistry 1998 1.81
49 Conditional dihydrostreptomycin resistance in Bacillus subtilis. J Bacteriol 1972 1.77
50 Negative regulation of Bacillus subtilis sporulation by the spo0E gene product. J Bacteriol 1991 1.76
51 Location of the targets of the hpr-97, sacU32(Hy), and sacQ36(Hy) mutations in upstream regions of the subtilisin promoter. J Bacteriol 1988 1.74
52 Aspartyl-phosphate phosphatases deactivate the response regulator components of the sporulation signal transduction system in Bacillus subtilis. Mol Microbiol 1996 1.66
53 The transition state transcription regulator AbrB of Bacillus subtilis is autoregulated during vegetative growth. Mol Microbiol 1989 1.59
54 A novel histidine kinase inhibitor regulating development in Bacillus subtilis. Genes Dev 1997 1.58
55 Genetic mapping of a linked cluster of ribosomal ribonucleic acid genes in Bacillus subtilis. J Bacteriol 1981 1.57
56 Antibacterial agents that inhibit two-component signal transduction systems. Proc Natl Acad Sci U S A 1998 1.53
57 Gene-enzyme relationships of aromatic acid biosynthesis in Bacillus subtilis. J Bacteriol 1973 1.53
58 Formation of a novel four-helix bundle and molecular recognition sites by dimerization of a response regulator phosphotransferase. Mol Cell 1998 1.51
59 Identification of the 37-kDa protein displaying a variable interaction with the erythroid cell membrane as glyceraldehyde-3-phosphate dehydrogenase. J Biol Chem 1987 1.50
60 Selection of cells transformed to prototrophy for sporulation markers. J Bacteriol 1971 1.50
61 Bacterial locomotion and signal transduction. J Bacteriol 1998 1.50
62 Structural alterations in the Bacillus subtilis Spo0A regulatory protein which suppress mutations at several spo0 loci. J Bacteriol 1990 1.48
63 Identification of a second oligopeptide transport system in Bacillus subtilis and determination of its role in sporulation. Mol Microbiol 1994 1.48
64 Mutational dissociation of the positive and negative regulatory properties of the Spo0A sporulation transcription factor of Bacillus subtilis. Gene 1991 1.44
65 Phosphorylation of Spo0A activates its stimulation of in vitro transcription from the Bacillus subtilis spoIIG operon. Mol Microbiol 1993 1.44
66 New cluster of ribosomal genes in Bacillus subtilis with regulatory role in sporulation. Nature 1978 1.42
67 A positive feedback loop controls transcription of the spoOF gene, a component of the sporulation phosphorelay in Bacillus subtilis. Mol Microbiol 1993 1.42
68 Biochemical characterization of the essential GTP-binding protein Obg of Bacillus subtilis. J Bacteriol 1994 1.40
69 Genetics of Bacillus subtilis chemotaxis: isolation and mapping of mutations and cloning of chemotaxis genes. J Bacteriol 1983 1.40
70 Genetic analysis of the marine manganese-oxidizing Bacillus sp. strain SG-1: protoplast transformation, Tn917 mutagenesis, and identification of chromosomal loci involved in manganese oxidation. J Bacteriol 1993 1.39
71 cis-unsaturated fatty acids specifically inhibit a signal-transducing protein kinase required for initiation of sporulation in Bacillus subtilis. Mol Microbiol 1992 1.39
72 Protein aspartate phosphatases control the output of two-component signal transduction systems. Trends Genet 1996 1.35
73 Genetic and biochemical characterization of mutants of Bacillus subtilis defective in succinate dehydrogenase. J Bacteriol 1973 1.35
74 Deoxyribonucleic acid-binding proteins in vegetative Bacillus subtilis: alterations caused by stage O sporulation mutations. J Bacteriol 1975 1.35
75 Effects on Bacillus subtilis of a conditional lethal mutation in the essential GTP-binding protein Obg. J Bacteriol 1994 1.34
76 Cloning, sequencing, and expression of the genes encoding the adenosylcobalamin-dependent ethanolamine ammonia-lyase of Salmonella typhimurium. J Biol Chem 1990 1.31
77 The transition state regulator Hpr of Bacillus subtilis is a DNA-binding protein. J Biol Chem 1991 1.31
78 High-resolution NMR structure and backbone dynamics of the Bacillus subtilis response regulator, Spo0F: implications for phosphorylation and molecular recognition. Biochemistry 1997 1.25
79 A negative regulator linking chromosome segregation to developmental transcription in Bacillus subtilis. Mol Microbiol 1998 1.25
80 Identification of a membrane protein involved in activation of the KinB pathway to sporulation in Bacillus subtilis. J Bacteriol 1996 1.23
81 Molecular cloning of the spo0B sporulation locus in bacteriophage lambda. J Bacteriol 1982 1.23
82 Subunit composition and domain structure of the Spo0A sporulation transcription factor of Bacillus subtilis. J Biol Chem 1994 1.23
83 Alanine mutants of the Spo0F response regulator modifying specificity for sensor kinases in sporulation initiation. Mol Microbiol 1999 1.22
84 Developing inhibitors to selectively target two-component and phosphorelay signal transduction systems of pathogenic microorganisms. Curr Med Chem 2004 1.21
85 Developmental modulation of deoxyribonucleic acid-binding proteins of Bacillus subtilis during sporulation stages. J Bacteriol 1974 1.20
86 PAS-A domain of phosphorelay sensor kinase A: a catalytic ATP-binding domain involved in the initiation of development in Bacillus subtilis. Proc Natl Acad Sci U S A 2001 1.18
87 ScoC regulates peptide transport and sporulation initiation in Bacillus subtilis. J Bacteriol 1999 1.17
88 Physiological role of tryptophanase in control of tryptophan biosynthesis in Bacillus alvei. J Bacteriol 1966 1.16
89 Dissection of the functional and structural domains of phosphorelay histidine kinase A of Bacillus subtilis. J Bacteriol 2001 1.14
90 KapB is a lipoprotein required for KinB signal transduction and activation of the phosphorelay to sporulation in Bacillus subtilis. Mol Microbiol 1997 1.13
91 Purification and some properties of tryptophanase from Bacillus alvei. Biochemistry 1966 1.13
92 Crystal structure of a phosphatase-resistant mutant of sporulation response regulator Spo0F from Bacillus subtilis. Structure 1996 1.13
93 Characterization of the spoIVB and recN loci of Bacillus subtilis. J Bacteriol 1990 1.12
94 A phosphotransferase activity of the Bacillus subtilis sporulation protein Spo0F that employs phosphoramidate substrates. Biochemistry 1996 1.06
95 The Bacillus subtilis response regulator Spo0A stimulates transcription of the spoIIG operon through modification of RNA polymerase promoter complexes. J Mol Biol 1996 1.05
96 Studies on the control of development: isolation of Bacillus subtilis mutants blocked early in sporulation and defective in synthesis of highly phosphorylated nucleotides. Proc Natl Acad Sci U S A 1977 1.05
97 Genetics of the alpha-ketoglutarate dehydrogenase complex of Bacillus subtilis. J Bacteriol 1978 1.04
98 A response regulatory protein with the site of phosphorylation blocked by an arginine interaction: crystal structure of Spo0F from Bacillus subtilis. Biochemistry 1997 1.02
99 Characterization of interactions between a two-component response regulator, Spo0F, and its phosphatase, RapB. Biochemistry 1998 1.01
100 A source of response regulator autophosphatase activity: the critical role of a residue adjacent to the Spo0F autophosphorylation active site. Biochemistry 1998 1.01
101 Bacillus subtilis transcription regulator, Spo0A, decreases alkaline phosphatase levels induced by phosphate starvation. J Bacteriol 1993 0.99
102 Phosphotransacetylase from Bacillus subtilis: purification and physiological studies. Biochim Biophys Acta 1973 0.99
103 The mechanism of action of inhibitors of bacterial two-component signal transduction systems. J Biol Chem 2000 0.98
104 Unique DNA-binding protein in the serum of patients with various neoplasms. Nature 1975 0.97
105 Alterations in the flow of one-carbon units affect KinB-dependent sporulation in Bacillus subtilis. Mol Microbiol 1997 0.96
106 Signal transduction in Bacillus subtilis sporulation. Curr Opin Genet Dev 1993 0.95
107 Regulation of lactate dehydrogenase synthesis in Bacillus subtilis. Biochim Biophys Acta 1978 0.93
108 Regulation of the oxidative stress response by the hpr gene in Bacillus subtilis. J Gen Microbiol 1991 0.92
109 Structural studies and isolation of cDNA clones providing the complete sequence of rat liver dihydropteridine reductase. J Biol Chem 1987 0.91
110 Evidence that spo0A mutations are recessive in spo0A-/spo0A+ merodiploid strains of Bacillus subtilis. J Bacteriol 1978 0.91
111 1H, 15N, and 13C backbone chemical shift assignments, secondary structure, and magnesium-binding characteristics of the Bacillus subtilis response regulator, Spo0F, determined by heteronuclear high-resolution NMR. Protein Sci 1995 0.91
112 Serum ribonuclease activity in cancer patients. Br J Cancer 1978 0.91
113 Antibiotic resistance. A vancomycin surprise. Nature 1999 0.89
114 Phosphorylation of the Spo0B response regulator phosphotransferase of the phosphorelay initiating development in Bacillus subtilis. J Biol Chem 1998 0.88
115 Histidine kinase-mediated signal transduction systems of pathogenic microorganisms as targets for therapeutic intervention. Curr Drug Targets Infect Disord 2002 0.88
116 Panspermia, spores and the Bacillus subtilis genome. Nature 1997 0.87
117 The primary structure of the mitochondrial energy-linked nicotinamide nucleotide transhydrogenase deduced from the sequence of cDNA clones. J Biol Chem 1988 0.87
118 DNA-binding proteins in human serum. Biochem Biophys Res Commun 1975 0.86
119 The effect of supercoiling on the in vitro transcription of the spoIIA operon from Bacillus subtilis. Biochimie 1992 0.85
120 Physiological studies of biosynthetic indole excretion in Bacillus alvei. J Bacteriol 1971 0.85
121 Control of postexponential gene expression by transition state regulators. Biotechnology 1992 0.84
122 Identification of communication networks in Spo0F: a model for phosphorylation-induced conformational change and implications for activation of multiple domain bacterial response regulators. FEBS Lett 1998 0.82
123 Purification and preliminary crystallographic studies on the sporulation response regulatory phosphotransferase protein, Spo0B, from Bacillus subtilis. Proteins 1997 0.79
124 Evidence for a physiological maximal typtophan pool level in Bacillus alvei. J Bacteriol 1966 0.79
125 Amino acid sequence of the signal peptide of mitochondrial nicotinamide nucleotide transhydrogenase as determined from the sequence of its messenger RNA. Biochem Biophys Res Commun 1988 0.79
126 Purification and identification of a human-serum DNA-binding protein associated with malignant diseases. Eur J Biochem 1976 0.78
127 Crystallization and preliminary X-ray analysis of a Y13S mutant of Spo0F from Bacillus subtilis. Acta Crystallogr D Biol Crystallogr 1996 0.78
128 Functional Genomics of Gram-Positive Microorganisms: review of the meeting, San Diego, California, 24 to 28 June 2001. J Bacteriol 2001 0.77
129 Sporulation in prokaryotes and lower eukaryotes. Curr Opin Genet Dev 1992 0.77
130 On the conservation of aminoacyl-transfer ribonucleic acid synthetase genes in Bacillus. J Bacteriol 1973 0.75
131 Physical and catalytic properties of tryptophanase from Bacillus alvei. Biochemistry 1966 0.75
132 A clinical evaluation of serum C3DP levels in individuals with malignant diseases. Cancer Res 1977 0.75
133 A correlation of serum C3DP levels with chemotherapeutic management of cancer patients. Cancer 1978 0.75
134 Strategies for cloning in Bacillus subtilis. Basic Life Sci 1982 0.75
135 Aspartyl phosphates in the regulatory control of bacterial response. Amino Acids 1994 0.75
136 Characterization of antigens on human lymphocytes coded by messenger RNA translated in vitro. Mol Immunol 1982 0.75
137 Expression of alkaline phosphatase from cloned human tumor cell lines in human/mouse somatic cell hybrids. Oncodev Biol Med 1982 0.75