Published in Yale J Biol Med on December 01, 1973
Cholera toxin mimics melanocyte stimulating hormone in inducing differentiation in melanoma cells. Proc Natl Acad Sci U S A (1974) 1.15
Mechanisms of differentiation in melanoma cells and melanocytes. Environ Health Perspect (1989) 0.97
Role of BMP-4 and Its Signaling Pathways in Cultured Human Melanocytes. Int J Cell Biol (2009) 0.80
p21-activated kinase 4 critically regulates melanogenesis via activation of the CREB/MITF and β-catenin/MITF pathways. J Invest Dermatol (2015) 0.80
Interferons modulate the expression of hormone receptors on the surface of murine melanoma cells. J Clin Invest (1989) 0.79
Enhanced melanogenesis of murine melanoma cells cultured on or in collagen gel. Arch Dermatol Res (1990) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol (1971) 37.53
Radioimmunoassay for the measurement of adenosine 3',5'-cyclic phosphate. Proc Natl Acad Sci U S A (1969) 7.81
The similarity of effects of vasopressin, adenosine-3',5'-phosphate (cyclic AMP) and theophylline on the toad bladder. J Clin Invest (1962) 4.19
The role of adenosine 3',5'-phosphate in the action of antidiuretic hormone. Am J Med (1967) 3.31
Cyclic nucleotide-dependent protein kinases. VI. Isolation and partial purification of a protein kinase activated by guanosine 3',5'-monophosphate. J Biol Chem (1970) 2.89
Prostaglandin receptor site: evidence for an essential role in the action of luteinizing hormone. Science (1970) 1.49
Effects of calcium on ACTH stimulation of the adrenal: separation of hormone binding from adenyl cyclase activation. Nature (1970) 1.36
Effects of cyclic adenosine monophosphate and melanocyte-stimulating hormone on frog skin in vitro. Nature (1965) 1.34
Radioimmunoassay of the F prostaglandins. J Clin Endocrinol Metab (1971) 1.33
Adenosine 3',5'-monophosphate (cyclic AMP) as the mediator of the actions of melanocyte stimulating hormone (MSH) and norepinephrine on the frog skin. Endocrinology (1969) 1.29
Biochemical characterization and cytochemical localization of a catecholamine-sensitive adenylate cyclase in isolated capillary endothelium. Proc Natl Acad Sci U S A (1972) 1.23
Cytochalasin B reversibly inhibits melanin granule movement in melanocytes. Nature (1971) 1.21
Cytochalasin B and pigment granule translocation. Cytochalasin B reverses and prevents pigment granule dispersion caused by dibutyryl cyclic AMP and theophylline in Rana pipiens Melanocytes. J Cell Biol (1972) 1.15
Mechanism of hormone action. Nature (1959) 1.10
Quantitative conversion of PGA or PGE to PGB. Prostaglandins (1972) 0.91
Effects of chemical and enzymatic modifications of glucagon on its activation of hepatic adenyl cyclase. Endocrinology (1969) 0.86
Chemical mediation of hormone action. Annu Rev Med (1972) 0.79
Rising variance: a leading indicator of ecological transition. Ecol Lett (2006) 5.94
Early warnings of regime shifts: a whole-ecosystem experiment. Science (2011) 3.64
Purification and properties of the light-activated cyclic nucleotide phosphodiesterase of rod outer segments. J Biol Chem (1975) 2.72
A light-activated GTPase in vertebrate photoreceptors: regulation of light-activated cyclic GMP phosphodiesterase. Proc Natl Acad Sci U S A (1977) 2.34
Studies of PPLO infection. II. The neurotoxin of Mycoplasma neurolyticum. J Exp Med (1966) 2.34
Leading indicators of trophic cascades. Ecol Lett (2007) 2.25
Characterization of the in vitro biotransformation of the HIV-1 reverse transcriptase inhibitor nevirapine by human hepatic cytochromes P-450. Drug Metab Dispos (1999) 2.18
Extended storage of red blood cells under anaerobic conditions. Vox Sang (2007) 1.82
Pharmacokinetics of nevirapine: initial single-rising-dose study in humans. Antimicrob Agents Chemother (1993) 1.62
Adenyl cyclase as a link between photon capture and changes in membrane permeability of frog photoreceptors. Proc Natl Acad Sci U S A (1971) 1.60
Regulation of cyclic nucleotide concentrations in photoreceptors: an ATP-dependent stimulation of cyclic nucleotide phosphodiesterase by light. Proc Natl Acad Sci U S A (1973) 1.58
Light-regulated enzymes of vertebrate retinal rods. Adv Cyclic Nucleotide Res (1979) 1.47
Predicting normal tissue response to radiotherapy. Int J Radiat Oncol Biol Phys (1999) 1.39
Effects of cyclic adenosine monophosphate and melanocyte-stimulating hormone on frog skin in vitro. Nature (1965) 1.34
Cyclic GMP-specific, high affinity, noncatalytic binding sites on light-activated phosphodiesterase. J Biol Chem (1980) 1.34
Reciprocal effects of an inhibitory factor on catalytic activity and noncatalytic cGMP binding sites of rod phosphodiesterase. Proc Natl Acad Sci U S A (1982) 1.33
Radioimmunoassay of the F prostaglandins. J Clin Endocrinol Metab (1971) 1.33
The phosphorylation state of phosducin determines its ability to block transducin subunit interactions and inhibit transducin binding to activated rhodopsin. J Biol Chem (1994) 1.31
A link between rhodopsin and disc membrane cyclic nucleotide phosphodiesterase. Action spectrum and sensitivity to illumination. Biochemistry (1975) 1.31
Purification of rat spermatogenic cells and preliminary biochemical analysis of these cells. Biol Reprod (1981) 1.29
Studies of PPLO infection. IV. The neurotoxicity of intact mycoplasmas, and their production of toxin in vivo and in vitro. J Exp Med (1966) 1.28
Biological effect of epidermal growth factor on the in vitro growth of human tumors. Cancer Res (1987) 1.25
Biochemical characterization and cytochemical localization of a catecholamine-sensitive adenylate cyclase in isolated capillary endothelium. Proc Natl Acad Sci U S A (1972) 1.23
Methaemoglobin formation by Mycoplasma gallisepticum: the role of hydrogen peroxide. Nature (1966) 1.23
Lipid-based delivery systems for improving the bioavailability and lymphatic transport of a poorly water-soluble LTB4 inhibitor. J Pharm Sci (1998) 1.22
Micropinocytic ingestion of glycosylated albumin by isolated microvessels: possible role in pathogenesis of diabetic microangiopathy. Proc Natl Acad Sci U S A (1981) 1.22
Cellular responses to cyclic AMP. Prog Biophys Mol Biol (1973) 1.22
Isolation and characterization of brain endothelial cells: morphology and enzyme activity. J Neurochem (1980) 1.21
The regulatory subunit of adenylate cyclase interacts with cytoskeletal components. Nature (1981) 1.19
Cholera toxin activation of adenylate cyclase in cancer cell membrane fragments. Proc Natl Acad Sci U S A (1975) 1.14
Histone variants in rat spermatogonia and primary spermatocytes. Dev Biol (1985) 1.12
Interactions between the subunits of transducin and cyclic GMP phosphodiesterase in Rana catesbiana rod photoreceptors. J Biol Chem (1990) 1.12
Early warnings of unknown nonlinear shifts: a nonparametric approach. Ecology (2011) 1.12
Megalourethra. J Urol (1986) 1.11
Initial slope of radiation survival curves is characteristic of the origin of primary and established cultures of human tumor cells and fibroblasts. Radiat Res (1987) 1.08
Light- and GTP-activated photoreceptor phosphodiesterase: regulation by a light-activated GTPase and identification of rhodopsin as the phosphodiesterase binding site. Adv Cyclic Nucleotide Res (1978) 1.08
Laparoscopic orchiopexy: procedure of choice for the nonpalpable testis? J Urol (1998) 1.07
Activation of photoreceptor disk membrane phosphodiesterase by light and ATP. Adv Cyclic Nucleotide Res (1975) 1.06
Evidence for separate epinephrine and glucagon responsive adenyl cyclase systems in rat liver. Biochem Biophys Res Commun (1968) 1.06
Inhibitory effects of alloxan on mammalian adenyl cyclase. J Pharmacol Exp Ther (1969) 1.06
Activation mechanism of rod outer segment cyclic GMP phosphodiesterase. Release of inhibitor by the GTP/GTP-binding protein. J Biol Chem (1983) 1.06
Light-activated GTPase in vertebrate photoreceptors. Nature (1977) 1.06
Heterogeneity in the development of apoptosis in irradiated murine tumours of different histologies. Int J Radiat Biol (1993) 1.05
Selective activation by short chain alcohols of glucagon responsive adenyl cyclase in liver. Endocrinology (1970) 1.05
Independent variation of glucagon and epinephrine responsive components of hepatic adenyl cyclase as a function of age, sex and steroid hormones. Endocrinology (1970) 1.04
Digitonin effects on photoreceptor adenylate cyclase. Science (1972) 1.04
Drug and radiation sensitivity measurements of successful primary monolayer culturing of human tumor cells using cell-adhesive matrix and supplemented medium. Cancer Res (1986) 1.04
The effects of exogenous progesterone and estradiol on prostaglandin F levels in ovariectomized ewes. Prostaglandins (1972) 1.03
Reversible sodium pump defect and swelling in the diabetic rat erythrocyte: effects on filterability and implications for microangiopathy. Proc Natl Acad Sci U S A (1989) 1.02
Calmodulin and calmodulin binding proteins in amphibian rod outer segments. Biochemistry (1987) 1.02
Isolation and biochemical studies of enriched populations of spermatogonia and early primary spermatocytes from rat testes. Biol Reprod (1986) 1.02
Location and fate of the nonpalpable testis in children. J Urol (1983) 1.01
The GTP-binding protein of rod outer segments. I. Role of each subunit in the GTP hydrolytic cycle. J Biol Chem (1987) 1.01
Selective effects of cholera toxin on the adrenaline responsive component of hepatic adenyl cyclase. Nature (1972) 1.01
A temperature-sensitive change in the energy of activation of hormone-stimulated hepatic adenylyl cyclase. Proc Natl Acad Sci U S A (1973) 1.01
Selective stimulation of epinephrine-responsive adenyl cyclase in mice by endotoxin. Proc Soc Exp Biol Med (1971) 1.01
Lesions of Cowper's glands in children. J Urol (1979) 1.00
The role of fludarabine-induced apoptosis and cell cycle synchronization in enhanced murine tumor radiation response in vivo. Cancer Res (1994) 1.00
Small fragments from the A subunit of cholera toxin capable of activating adenylate cyclase. Proc Natl Acad Sci U S A (1976) 1.00
Laparoscopic Fowler-Stephens orchiopexy for the high abdominal testis. J Urol (1999) 0.99
Target cell and mode of radiation injury in rhesus salivary glands. Radiother Oncol (1986) 0.99
Cyclic adenosine monophosphate: function in photoreceptors. Science (1971) 0.98
The effect of the gamma-subunit of the cyclic GMP phosphodiesterase of bovine and frog (Rana catesbiana) retinal rod outer segments on the kinetic parameters of the enzyme. Biochem J (1990) 0.98
Isolation of cyclic AMP and cyclic GMP by thin-layer chromatography. Application to assay of adenylate cyclase, guanylate cyclase, and cyclic nucleotide phosphodiesterase. Anal Biochem (1974) 0.98
Photoaffinity identification of colchicine-solubilized regulatory subunit from rat brain adenylate cyclase. J Neurochem (1984) 0.98
Cooperative binding of the retinal rod G-protein, transducin, to light-activated rhodopsin. J Biol Chem (1993) 0.97
Potential methods for predicting tumor radiocurability. Int J Radiat Oncol Biol Phys (1986) 0.96
Purification of rod outer segment GTP-binding protein subunits and cGMP phosphodiesterase by single-step column chromatography. Methods Enzymol (1988) 0.96
Characterization of high mobility group protein levels during spermatogenesis in the rat. J Biol Chem (1984) 0.96
Rethinking the role of phosducin: light-regulated binding of phosducin to 14-3-3 in rod inner segments. Proc Natl Acad Sci U S A (2001) 0.96
Structural and functional consequences of increased tubulin glycosylation in diabetes mellitus. Proc Natl Acad Sci U S A (1982) 0.95
Intrinsic radiosensitivity of normal human fibroblasts and lymphocytes after high- and low-dose-rate irradiation. Cancer Res (1992) 0.95
Prospective comparison of in vitro normal cell radiosensitivity and normal tissue reactions in radiotherapy patients. Int J Radiat Oncol Biol Phys (1993) 0.95
Functional exchange of components between light-activated photoreceptor phosphodiesterase and hormone-activated adenylate cyclase systems. Proc Natl Acad Sci U S A (1982) 0.94
Distribution and synthesis of histone 1 subfractions during spermatogenesis in the rat. Exp Cell Res (1982) 0.93
Modulation of the G protein regulator phosducin by Ca2+/calmodulin-dependent protein kinase II phosphorylation and 14-3-3 protein binding. J Biol Chem (2001) 0.93
Reducing the duration of mechanical ventilation: three examples of change in the intensive care unit. New Horiz (1998) 0.93
Isolation and characterization of TH2A, a germ cell-specific variant of histone 2A in rat testis. J Biol Chem (1982) 0.93
Comparison of the phosphodiesterase inhibitory subunit interactions of frog and bovine rod outer segments. Biochem J (1989) 0.92
Post-hypospadias repair urethral strictures: a review of 30 cases. J Urol (1988) 0.92
The role of cyclic AMP in visual excitation. Adv Cyclic Nucleotide Res (1972) 0.92
Proarrhythmic safety of repeat doses of mirabegron in healthy subjects: a randomized, double-blind, placebo-, and active-controlled thorough QT study. Clin Pharmacol Ther (2012) 0.91
The dependence of the substrate specificity on the conformation of crystalline glutamate dehydrogenase. J Biol Chem (1965) 0.91
Nuclear protein transitions during spermatogenesis. Fed Proc (1978) 0.91
Biologic activity of purified cotton bract extracts in man and guinea pig. Environ Health Perspect (1986) 0.91
A specific, reversible, macromolecular inhibitor of hepatic glucagon responsive adenyl cyclase. Endocrinology (1971) 0.90
A GTP-protein activator of phosphodiesterase which forms in response to bleached rhodopsin. J Cyclic Nucleotide Res (1981) 0.90
How much could the radiotherapy dose be altered for individual patients based on a predictive assay of normal-tissue radiosensitivity? Radiother Oncol (1996) 0.89
Studies on nicotinamide adenine dinucleotide phosphate reductase of spinach chloroplasts. J Biol Chem (1972) 0.89
Pharmacokinetics of transdermally delivered clonidine. Clin Pharmacol Ther (1985) 0.89
Meiotic synthesis of testis histones in the rat. Proc Natl Acad Sci U S A (1980) 0.89
Laparoscopy for localization of nonpalpable testes. J Urol (1984) 0.88