Published in Hum Genet on January 25, 1979
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Engineered GFP as a vital reporter in plants. Curr Biol (1996) 9.03
Hepatitis C virus infection is associated with the development of hepatocellular carcinoma. Proc Natl Acad Sci U S A (1990) 6.96
Identification of Xenopus SMC protein complexes required for sister chromatid cohesion. Genes Dev (1998) 5.78
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The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells. J Exp Med (1988) 4.31
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ATP-dependent positive supercoiling of DNA by 13S condensin: a biochemical implication for chromosome condensation. Cell (1997) 3.95
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Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib. J Bone Miner Res (2000) 3.86
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Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2). Proc Natl Acad Sci U S A (1985) 3.46
A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells. EMBO J (1996) 3.40
Molecular structure of human lymphocyte receptor for immunoglobulin E. Cell (1986) 3.34
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Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p. Nat Genet (1994) 3.17
IL-6 is produced by osteoblasts and induces bone resorption. J Immunol (1990) 3.14
Chemical nature of the light emitter of the Aequorea green fluorescent protein. Proc Natl Acad Sci U S A (1996) 3.12
Molecular cloning and characterization of a surface antigen preferentially overexpressed on multiple myeloma cells. Biochem Biophys Res Commun (1999) 3.03
Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells. J Immunol (1989) 3.01
Analysis of upstream elements in the HuC promoter leads to the establishment of transgenic zebrafish with fluorescent neurons. Dev Biol (2000) 2.93
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Non-invasive quantitative detection and applications of non-toxic, S65T-type green fluorescent protein in living plants. Plant J (1999) 2.88
B cell stimulating factor 2/interleukin 6 is a costimulant for human thymocytes and T lymphocytes. J Exp Med (1988) 2.88
Extracellular signal-dependent nuclear import of Stat1 is mediated by nuclear pore-targeting complex formation with NPI-1, but not Rch1. EMBO J (1997) 2.80
AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6. Proc Natl Acad Sci U S A (1990) 2.79
Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production. Proc Natl Acad Sci U S A (1987) 2.76
Human apolipoprotein B: structure of carboxyl-terminal domains, sites of gene expression, and chromosomal localization. Science (1985) 2.72
HEAT repeats associated with condensins, cohesins, and other complexes involved in chromosome-related functions. Genome Res (2000) 2.66
Transmission of bacteriocinogenicity by conjugation in group D streptococci. Jpn J Microbiol (1973) 2.60
Xklp1, a chromosomal Xenopus kinesin-like protein essential for spindle organization and chromosome positioning. Cell (1995) 2.57
Purification of exfoliatin produced by Staphylococcus aureus of bacteriophage group 2 and its physicochemical properties. Infect Immun (1973) 2.50
Interleukin-6 (IL-6) functions as an in vitro autocrine growth factor in renal cell carcinomas. FEBS Lett (1989) 2.43
Establishment of an interleukin 6 (IL 6)/B cell stimulatory factor 2-dependent cell line and preparation of anti-IL 6 monoclonal antibodies. Eur J Immunol (1988) 2.41
Constitutive and interleukin-1 (IL-1)-inducible factors interact with the IL-1-responsive element in the IL-6 gene. Mol Cell Biol (1990) 2.41
Recombinant human interleukin-6 (IL-6/BSF-2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes. FEBS Lett (1988) 2.39
Association of dopamine D2 receptor molecular variant with schizophrenia. Lancet (1994) 2.36
STAT3 is required for the gp130-mediated full activation of the c-myc gene. J Exp Med (1999) 2.36
Receptors for B cell stimulatory factor 2. Quantitation, specificity, distribution, and regulation of their expression. J Exp Med (1987) 2.34
Pro-sequence of subtilisin can guide the refolding of denatured subtilisin in an intermolecular process. Nature (1989) 2.33
The fission yeast cut1+ gene regulates spindle pole body duplication and has homology to the budding yeast ESP1 gene. Cell (1990) 2.32
Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis. Immunity (1999) 2.31
Induction of IL-6 (B cell stimulatory factor-2/IFN-beta 2) production by HIV. J Immunol (1989) 2.27
Molecular analysis of the Smith-Magenis syndrome: a possible contiguous-gene syndrome associated with del(17)(p11.2). Am J Hum Genet (1991) 2.26
Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice. Cell (1995) 2.25
Fracture on removal of the ACE tibial nail. J Bone Joint Surg Br (1997) 2.23
Isolation and characterization of simian immunodeficiency virus from mandrills in Africa and its relationship to other human and simian immunodeficiency viruses. J Virol (1988) 2.17
Chromosome condensation by a human condensin complex in Xenopus egg extracts. J Biol Chem (2001) 2.17
Mercury and cadmium resistances mediated by the penicillinase plasmid in Staphylococcus aureus. J Bacteriol (1974) 2.09
Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation. EMBO J (1996) 2.07
Recombinant human B cell stimulatory factor 2 (BSF-2/IFN-beta 2) regulates beta-fibrinogen and albumin mRNA levels in Fao-9 cells. FEBS Lett (1987) 2.04
Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells. J Biol Chem (1997) 2.02
Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice. Proc Natl Acad Sci U S A (1992) 2.01
Cytomegalovirus infection. Viral ultrastructure with particular reference to the relationship of lysosomes to cytoplasmic inclusions. Am J Pathol (1966) 1.99
Erythroid cell differentiation: murine erythroleukemia cell variant with unique pattern of induction by polar compounds. Proc Natl Acad Sci U S A (1976) 1.99
Activation of mitogen-activated protein kinases/extracellular signal-regulated kinases in human hepatocellular carcinoma. Hepatology (1998) 1.97
Dual roles of the 11S regulatory subcomplex in condensin functions. Proc Natl Acad Sci U S A (2000) 1.96
Induction of rat acute-phase proteins by interleukin 6 in vivo. Eur J Immunol (1988) 1.95
Role of Gab1 in heart, placenta, and skin development and growth factor- and cytokine-induced extracellular signal-regulated kinase mitogen-activated protein kinase activation. Mol Cell Biol (2000) 1.92
Dissection of signaling cascades through gp130 in vivo: reciprocal roles for STAT3- and SHP2-mediated signals in immune responses. Immunity (2000) 1.92
IL-6/BSF-2 functions as a killer helper factor in the in vitro induction of cytotoxic T cells. J Immunol (1988) 1.92
Effect of recombinant IL 2 and gamma-IFN on proliferation and differentiation of human B cells. J Immunol (1985) 1.92
Oxygen radicals in influenza-induced pathogenesis and treatment with pyran polymer-conjugated SOD. Science (1989) 1.91
Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/interleukin 6. Mol Cell Biol (1988) 1.89
An experimental study of a combination method using a pedicle screw and laminar hook for the osteoporotic spine. Spine (Phila Pa 1976) (1997) 1.88
The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein. Nat Genet (1999) 1.87
A novel maternally expressed gene, ATP10C, encodes a putative aminophospholipid translocase associated with Angelman syndrome. Nat Genet (2001) 1.86
Genomic structure of the murine IL-6 gene. High degree conservation of potential regulatory sequences between mouse and human. J Immunol (1988) 1.86
Regulation of BSF-2/IL-6 production by human mononuclear cells. Macrophage-dependent synthesis of BSF-2/IL-6 by T cells. J Immunol (1988) 1.85
Autoregulation of the Stat3 gene through cooperation with a cAMP-responsive element-binding protein. J Biol Chem (1998) 1.83
Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors. Blood (1999) 1.83
Association between interleukin-18 gene polymorphism 105A/C and asthma. Clin Exp Allergy (2003) 1.80
Characterization of IL-6 receptor expression by monoclonal and polyclonal antibodies. J Immunol (1989) 1.80
Bimodal activation of SMC ATPase by intra- and inter-molecular interactions. EMBO J (2001) 1.78
Regulation of interleukin-6 expression in cultured human blood monocytes and monocyte-derived macrophages. Blood (1988) 1.76
Cloning of a phosphate-regulated hemolysin gene (phospholipase C) from Pseudomonas aeruginosa. J Bacteriol (1982) 1.76
Action of recombinant human interleukin 6, interleukin 1 beta and tumor necrosis factor alpha on the mRNA induction of acute-phase proteins. Eur J Immunol (1988) 1.76
Solubilization of human erythrocyte membrane glycoproteins and separation of the MN glycoprotein from a glycoprotein with I, S, and A activity. Biochim Biophys Acta (1972) 1.75
Effects of a novel free radical scavenger, MCl-186, on ischemic brain damage in the rat distal middle cerebral artery occlusion model. J Pharmacol Exp Ther (1997) 1.74
OPC-41061, a highly potent human vasopressin V2-receptor antagonist: pharmacological profile and aquaretic effect by single and multiple oral dosing in rats. J Pharmacol Exp Ther (1998) 1.74
ATP-dependent aggregation of single-stranded DNA by a bacterial SMC homodimer. EMBO J (1998) 1.74
Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor alpha associated with age-dependent cardiac toxicity. J Biol Chem (2000) 1.73
The changing histopathology of lung cancer: a review of 1682 cases. Cancer (1977) 1.72
Evaluation of the pharyngeal airway in patients with sleep apnea: value of ultrafast MR imaging. AJR Am J Roentgenol (1993) 1.71
Plasma clearance, organ distribution and target cells of interleukin-6/hepatocyte-stimulating factor in the rat. Eur J Biochem (1988) 1.69
Purification and characterization of soluble human IL-6 receptor expressed in CHO cells. J Biochem (1990) 1.69
Ablation of cerebellar Golgi cells disrupts synaptic integration involving GABA inhibition and NMDA receptor activation in motor coordination. Cell (1998) 1.69
A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia. Hum Mol Genet (1997) 1.68