Published in Clin Pharmacol Ther on April 01, 1979
Differential effects of enzyme induction on antipyrine metabolite formation. Br J Clin Pharmacol (1982) 1.43
Enzyme induction and beta-adrenergic receptor blocking drugs. Br J Clin Pharmacol (1984) 0.86
Decreased plasma concentrations and clinical effects of alprenolol during combined treatment with pentobarbitone in hypertension. Br J Clin Pharmacol (1987) 0.75
Pharmacokinetic studies on the selective beta1-receptor antagonist metoprolol in man. J Pharmacokinet Biopharm (1974) 2.18
A survey of the pharmacological properties of metoprolol in animals and man. Acta Pharmacol Toxicol (Copenh) (1975) 2.01
Protein binding of diphenylhydantoin and desmethylimipramine in plasma from patients with poor renal function. N Engl J Med (1971) 1.76
Gas chromatographic assessment of the reproducibility of phenazone plasma half-life in young healthy volunteers. Eur J Clin Pharmacol (1974) 1.68
Metabolism of metoprolol-(3-h) in man, the dog and the rat. Acta Pharmacol Toxicol (Copenh) (1975) 1.61
Acetaminophen: potentially toxic metabolite formed by human fetal and adult liver microsomes and isolated fetal liver cells. Science (1979) 1.54
Identification, expression, and immunogenicity of Kaposi's sarcoma-associated herpesvirus-encoded small viral capsid antigen. J Virol (1997) 1.47
High plasma concentrations of beta-receptor blocking drugs and deficient debrisoquine hydroxylation. Lancet (1982) 1.46
In vitro inhibition of a polymorphic human liver P-450 isozyme by narcotic analgesics. Anesthesiology (1989) 1.44
Drug metabolism in human liver in vitro: establishment of a human liver bank. Clin Pharmacol Ther (1980) 1.39
Reversible renal failure during treatment with captopril. Br Med J (1979) 1.35
Purification of a new glutathione S-transferase (transferase mu) from human liver having high activity with benzo(alpha)pyrene-4,5-oxide. Biochem Biophys Res Commun (1981) 1.28
Glutathione transferases from human liver. Methods Enzymol (1985) 1.23
At Hershey: medical system near 'failure' during Three Mile Island. New Physician (1979) 1.22
Inhibition of desmethylimipramine 2-hydroxylation by drugs in human liver microsomes. Biochem Pharmacol (1985) 1.22
Bioavailability and pharmacokinetics of cimetidine. Eur J Clin Pharmacol (1979) 1.21
Distribution and elimination kinetics of carbamazepine in man. Eur J Clin Pharmacol (1975) 1.20
Short-term effects of felodipine, a new dihydropyridine, in hypertension. Br J Clin Pharmacol (1984) 1.14
Multitarget-ribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication--potential effectiveness against most presently sequenced HIV-1 isolates. Nucleic Acids Res (1992) 1.09
Long term experience of felodipine in combination with beta-blockade and diuretics in refractory hypertension. Drugs (1985) 1.08
Binding of two adrenergic beta-receptor antagonists, alprenolol and H 93-26, to human serum proteins. Acta Pharm Suec (1974) 1.07
Absorption of ocular timolol. Clin Pharmacokinet (1980) 1.06
Effect of pentobarbital on the disposition of alprenolol. Clin Pharmacol Ther (1977) 1.06
Identification of a new glutathione S-transferase in human liver. Acta Chem Scand B (1980) 1.05
Prazosin dynamics in hypertension: relationship to plasma concentration. Clin Pharmacol Ther (1981) 1.04
Plasma levels and effects of metoprolol on blood pressure, adrenergic beta receptor blockade, and plasma renin activity in essential hypertension. Clin Pharmacol Ther (1976) 1.04
Gas chromatographic determination of ethosuximide and phensuximide in plasma and urine of man. J Pharm Pharmacol (1973) 1.01
Removal of O6-methylguanine from DNA by human liver fractions. Proc Natl Acad Sci U S A (1982) 1.01
Trace analysis of methotrexate and 7-hydroxymethotrexate in human plasma and urine by a novel high-performance liquid chromatographic method. Ther Drug Monit (1991) 1.01
Pharmacokinetic studies of metoprolol-(3-h) in the rat and the dog. Acta Pharmacol Toxicol (Copenh) (1975) 1.00
Steady-state plasma concentrations of alprenolol in man. Eur J Clin Pharmacol (1974) 1.00
Homeobox gene Cdx1 regulates Ras, Rho and PI3 kinase pathways leading to transformation and tumorigenesis of intestinal epithelial cells. Oncogene (2001) 0.99
Glucuronidation of morphine in human liver and interaction with oxazepam. Acta Anaesthesiol Scand Suppl (1982) 0.98
Oxidation of (R)- and (S)-propranolol in human and dog liver microsomes. Species differences in stereoselectivity. J Pharmacol Exp Ther (1982) 0.97
Cytochrome P450 isoforms involved in melatonin metabolism in human liver microsomes. Eur J Clin Pharmacol (2001) 0.96
A comparative study of drug metabolism in the isolated perfused liver and in vivo in rats. Eur J Pharmacol (1970) 0.95
Combined pharmacokinetic and pharmacodynamic studies on alprenolol and 4-hydroxy-alprenolol in man. Life Sci (1974) 0.95
Phenotypic consistency in hydroxylation of desmethylimipramine and debrisoquine in healthy subjects and in human liver microsomes. Clin Pharmacol Ther (1984) 0.93
Glucuronidation of codeine and morphine in human liver and kidney microsomes: effect of inhibitors. Pharmacol Toxicol (1990) 0.93
Cytochrome P-450-dependent oxidation of felodipine--a 1,4-dihydropyridine--to the corresponding pyridine. Xenobiotica (1984) 0.92
Metabolism of metoprolol in the rat in vitro and in vivo. Xenobiotica (1976) 0.92
On the significance of drug-induced spectral changes in liver microsomes. Biochem Soc Symp (1972) 0.92
Influence of pentobarbital on metoprolol plasma levels. Clin Pharmacol Ther (1979) 0.92
Pharmacokinetics and pharmacodynamics of alprenolol in the treatment of hypertension. II. Relationship to its effect on blood pressure and plasma renin activity. Eur J Clin Pharmacol (1976) 0.92
Tissue distribution of metoprolol-(3-h) in the mouse and the rat. Acta Pharmacol Toxicol (Copenh) (1975) 0.91
Pharmacokinetics of felodipine in patients with liver disease. Eur J Clin Pharmacol (1989) 0.91
Expression of additional genes in a vector derived from a minimal RNA virus. Virology (1996) 0.90
Prazosin first dose phenomenon during combined treatment with a beta-adrenoceptor blocker in hypertensive patients. Br J Clin Pharmacol (1982) 0.89
Interindividual differences in drug oxidation: clinical importance. Drug Metab Dispos (1974) 0.89
Distribution of remoxipride to the human brain and central D2-dopamine receptor binding examined in vivo by PET. Acta Psychiatr Scand Suppl (1990) 0.88
Relative bioavailability of a paracetamol suppository. Eur J Clin Pharmacol (1980) 0.88
Contribution of 4-hydroxy-alprenolol to adrenergic beta receptor blockade of alprenolol. Clin Pharmacol Ther (1979) 0.88
Cyclosporine plasma levels in renal transplant patients. Association with renal toxicity and allograft rejection. Transplantation (1985) 0.88
Correlation between nortriptyline and debrisoquine hydroxylation in the human liver. Life Sci (1983) 0.88
Metabolism of carbamazepine and its epoxide metabolite in human and rat liver in vitro. Drug Metab Dispos (1982) 0.87
Additive intraocular pressure reducing effect of topical timolol during systemic beta-blockade. Acta Ophthalmol (Copenh) (1982) 0.87
Interaction between salicylic acid and indomethacin in binding to human serum albumin. Acta Pharm Suec (1975) 0.87
Chlormethiazole as an efficient inhibitor of cytochrome P450 2E1 expression in rat liver. J Pharmacol Exp Ther (1994) 0.87
Locked doors in acute inpatient psychiatry: a literature review. J Psychiatr Ment Health Nurs (2009) 0.86
Cbl escapes Cdc42-mediated inhibition by downregulation of the adaptor molecule betaPix. Oncogene (2006) 0.86
Histone complements of human tissues, carcinomas, and carcinoma-derived cell lines. Mol Cell Biochem (1984) 0.86
Extraction and metabolism of lidocaine in rat liver. Acta Pharmacol Toxicol (Copenh) (1977) 0.86
Determination of adrenaline and noradrenaline in plasma by an isotope derivative method and ion pair liquid chromatography. Acta Pharm Suec (1977) 0.86
Distress, quality of life and strategies to 'keep a good mood' in patients with carcinoid tumours: patient and staff perceptions. Eur J Cancer Care (Engl) (2003) 0.86
Plasma levels and effects of metoprolol after single and multiple oral doses. Clin Pharmacol Ther (1980) 0.86
Additive renal effects of indomethacin and dipyridamole in man. Br J Clin Pharmacol (1987) 0.86
Importance of "first-pass elimination" for interindividual differences in steady-state concentrations of the adrenergic beta-receptor antagonist alprenolol. J Pharmacokinet Biopharm (1977) 0.86
Time course of blood pressure, pulse rate, plasma renin and metoprolol during treatment of hypertensive patients. Eur J Clin Pharmacol (1980) 0.85
Human liver microsomal cytochrome P-450IIE1. Immunological evaluation of its contribution to microsomal ethanol oxidation, carbon tetrachloride reduction and NADPH oxidase activity. Biochem Pharmacol (1989) 0.85
Pharmacokinetics and haemodynamic effects of felodipine as monotherapy in hypertensive patients. Clin Invest Med (1987) 0.85
The possible role of cytochrome P-450 in the liver "first pass elimination" of a beta-receptor blocking drug. Acta Pharmacol Toxicol (Copenh) (1974) 0.84
Alternariol induces abnormal nuclear morphology and cell cycle arrest in murine RAW 264.7 macrophages. Toxicol Lett (2013) 0.84
Quinidine dosage, with special reference to an oral loading dose schedule. Br J Clin Pharmacol (1979) 0.84
Alpha-receptor function changes after the first dose of prazosin. Clin Pharmacol Ther (1982) 0.84
Clinical value of assessing prednisolone pharmacokinetics before and after renal transplantation. Eur J Clin Pharmacol (1984) 0.84
Determination of (R)-AND (S)-alprenolol-and (R)- and (S)-metoprolol as their diastereomeric derivatives in human plasma by reversed-phase liquid chromatography. J Chromatogr (1982) 0.83
Absorption, distribution and excretion of alprenolol in man, dog and rat. Acta Pharmacol Toxicol (Copenh) (1974) 0.83
Acetylation of procaine amide in man. A preliminary communication. Eur J Clin Pharmacol (1975) 0.83
Comparative metabolism of debrisoquine, 7-ethoxyresorufin and benzo(a)pyrene in liver microsomes from humans, and from rats treated with cytochrome P-450 inducers. Acta Pharmacol Toxicol (Copenh) (1985) 0.83