Published in J Gen Virol on May 01, 1972
Interferon induction by synthetic polynucleotides: importance of purine N-7 and strandwise rearrangement. Proc Natl Acad Sci U S A (1974) 1.12
Interferon induction in cynomolgus and rhesus monkey after repeated doses of a modified polyriboinosinic-polyribocytidylic acid complex. Antimicrob Agents Chemother (1977) 1.01
Murine cytomegalovirus: induction of and sensitivity to interferon in vitro. Infect Immun (1975) 0.93
Enhancement of interferon production in mouse cell line, a high-yielding source of mouse interferon. Appl Microbiol (1973) 0.84
Studies on the mechanism of the priming effect of interferon on interferon production by cell cultures exposed to poly(rI)-poly(rC). Infect Immun (1973) 0.82
Replication of semliki forest virus: three forms of viral RNA produced during infection. Proc Natl Acad Sci U S A (1966) 3.23
How can experience in clinical and community settings contribute to early medical education? A BEME systematic review. Med Teach (2006) 3.11
A modified polyriboinosinic-polyribocytidylic acid complex that induces interferon in primates. J Infect Dis (1975) 2.14
Identification of mouse chromosomes required for murine leukemia virus replication. Cell (1977) 2.05
Inhibition of tumor growth by polyinosinic-polycytidylic acid. Proc Natl Acad Sci U S A (1969) 2.00
Molecular basis of the action of interferon. J Mol Biol (1968) 1.70
Interferon preparations as modifiers of immune responses. Proc Soc Exp Biol Med (1972) 1.44
The recognition of viral RNA by mammalian ribosomes. An effect of interferon. Biochim Biophys Acta (1968) 1.44
Ribosomes: effect of interferon on their interaction with rapidly labeled cellular and viral RNA's. Science (1967) 1.44
myc family oncogene amplification in tumor cell lines established from small cell lung cancer patients and its relationship to clinical status and course. J Clin Invest (1987) 1.43
A phase I-II trial of multiple-dose polyriboinosic-polyribocytidylic acid in patieonts with leukemia or solid tumors. J Natl Cancer Inst (1976) 1.42
Inhibition of biologic activity of poly I: poly C by human plasma. Proc Soc Exp Biol Med (1970) 1.42
Characteristics of nine newly derived mesothelioma cell lines. Ann Thorac Surg (1995) 1.41
Long-term treatment of malignant gliomas with intramuscularly administered polyinosinic-polycytidylic acid stabilized with polylysine and carboxymethylcellulose: an open pilot study. Neurosurgery (1996) 1.39
Some factors affecting the interferon-induced antiviral state. Proc Soc Exp Biol Med (1967) 1.33
Successful prophylaxis against rabies in mice and Rhesus monkeys: the interferon system and vaccine. J Infect Dis (1977) 1.33
Effect of interferon on early interferon production. Science (1966) 1.30
Interferon action on parental Semliki forest virus ribonucleic acid. J Virol (1967) 1.28
An interdisciplinary method of classifying and monitoring medication errors. Am J Hosp Pharm (1985) 1.19
Effect of a nuclease-resistant derivative of polyriboinosinic-polyribocytidylic acid complex on yellow fever in rhesus monkeys (Macaca mulatta). J Infect Dis (1977) 1.19
The effect of polyinosinic-polycytidylic acid upon graft-vs-host activity in BALB/c mice. J Immunol (1970) 1.18
Interferon and uninfected cells. Proc Soc Exp Biol Med (1966) 1.15
RB protein status and clinical correlation from 171 cell lines representing lung cancer, extrapulmonary small cell carcinoma, and mesothelioma. Oncogene (1994) 1.12
Neuromedin B is present in lung cancer cell lines. Cancer Res (1992) 1.11
Modification of chronic hepatitis-B virus infection in chimpanzees by administration of an interferon inducer. Lancet (1976) 1.10
Interferon: lack of detectable uptake by cells. Science (1966) 1.09
Modified polyriboinosinic-polyribocytidylic acid, an immunological adjuvant. Infect Immun (1976) 1.09
Interferon and interferon inducers in the treatment of malignancies. Arch Intern Med (1970) 1.08
Protective and toxic effects of a nuclease-resistant derivative of polyriboinosinic-polyribocytidylic acid on Venezuelan equine encephalomyelitis virus in rhesus monkeys. J Infect Dis (1979) 1.07
Analysis of anthocyanins in foods by liquid chromatography, liquid chromatography-mass spectrometry and capillary electrophoresis. J Chromatogr A (2000) 1.06
Characterization of functional receptors for gastrointestinal hormones on human colon cancer cells. Cancer Res (1992) 1.06
Nonrandom structural and numerical chromosome changes in non-small-cell lung cancer. Genes Chromosomes Cancer (1991) 1.05
Modified polyriboinosinic-polyribocytidylic acid complex: sustained interferonemia and its physiological associates in humans. Infect Immun (1979) 1.05
Immunohistochemical analysis of the p16INK4 cyclin-dependent kinase inhibitor in malignant mesothelioma. J Natl Cancer Inst (1995) 1.04
Prophylactic and therapeutic efficacies of poly(IC.LC) against respiratory influenza A virus infection in mice. Antimicrob Agents Chemother (1995) 1.04
Swine influenza virus vaccine: potentiation of antibody responses in rhesus monkeys. Science (1977) 1.03
Lack of correlation between interferon induction and antitumour effect of poly I-poly C. Nat New Biol (1971) 1.02
Interferon induction in cynomolgus and rhesus monkey after repeated doses of a modified polyriboinosinic-polyribocytidylic acid complex. Antimicrob Agents Chemother (1977) 1.01
Initial clinical trials in cancer patients of polyriboinosinic-polyribocytidylic acid stabilized with poly-L-lysine, in carboxymethylcellulose [poly(ICLC)], a highly effective interferon inducer. Cancer Res (1979) 1.01
Phase I-II trials of poly IC stabilized with poly-L-lysine. Cancer Treat Rep (1978) 1.00
A preliminary trial of poly(I,C)-LC in multiple sclerosis. J Biol Response Mod (1985) 0.99
Postinfectious encephalopathy after treatment of herpes simplex encephalitis with acyclovir. Pediatr Infect Dis (1984) 0.99
Induction of interferon in lymphoblastoid cell lines. Proc Soc Exp Biol Med (1970) 0.96
Structure of a hydroxyl radical induced DNA-protein cross-link involving thymine and tyrosine in nucleohistone. Biochemistry (1989) 0.96
Protein expression of the RB-related gene family and SV40 large T antigen in mesothelioma and lung cancer. Oncogene (2000) 0.96
Interferon. Annu Rev Microbiol (1966) 0.95
Mechanisms of DEAE-dextran enhancement of polynucleotide induction of interferon. Proc Soc Exp Biol Med (1971) 0.94
Prophylactic control of simian hemorrhagic fever in monkeys by an interferon inducer, polyriboinosinic-polyribocytidylic acid-poly-L-lysine. J Infect Dis (1976) 0.91
Relationship between nutritional status and fatty acid synthesis by microsomal and soluble enzymes of pigeon liver. Arch Biochem Biophys (1966) 0.90
Studies on poly I:C toxicity in experimental animals. Toxicol Appl Pharmacol (1972) 0.90
Effect of interferon on togavirus and arenavirus infections of animals. Tex Rep Biol Med (1977) 0.89
The effect of polyinosinic:polycytidylic acid on tumor metabolism. Proc Soc Exp Biol Med (1970) 0.89
Polyinosinic-polycytidylic acid inhibits chemically induced tumorigenesis in mouse skin. Science (1970) 0.88
Dactinomycin: relative resistance of green monkey kidney cell cultures to its action. Proc Soc Exp Biol Med (1967) 0.88
Growth characteristics and immunocytochemical studies of reovirus type 2 in a line of human amnion cells. Arch Gesamte Virusforsch (1966) 0.88
The association of acetyl-coenzyme A carboxylase with the microsomal fraction of pigeon liver. Arch Biochem Biophys (1966) 0.88
Epidermal growth factor receptor monoclonal antibodies inhibit the growth of lung cancer cell lines. J Natl Cancer Inst Monogr (1992) 0.87
Treatment of intracranial alphavirus infections in mice by a combination of specific antibodies and an interferon inducer. Am J Trop Med Hyg (1995) 0.87
Production of monoclonal antibodies reacting with rat islet cell membrane antigens. Diabetes (1981) 0.87
Topical treatment of vaccinia virus infection with an interferon inducer in rabbits. J Infect Dis (1978) 0.86
Epstein-Barr virus and Herpesvirus saimiri: sensitivity to interferons and interferon inducers. J Natl Cancer Inst (1981) 0.86
Effect of interferon on RNA synthesis in Sindbis virus infected cells. Proc Soc Exp Biol Med (1966) 0.86
Lung carcinoid cell lines have bombesin-like peptides and EGF receptors. J Cell Biochem (1990) 0.86
Protein synthesis by amoebal ribosomes. Nature (1967) 0.85
Immunoprophylactic strategies against respiratory influenza virus infection. Vaccine (2001) 0.85
Effect of interferon treatment on cellular messenger RNA. Proc Natl Acad Sci U S A (1973) 0.85
Induction of interferon by preparations of synthetic single-stranded RNA. Proc Natl Acad Sci U S A (1969) 0.84
Historical overview of the use of polynucleotides in cancer. J Biol Response Mod (1985) 0.83
Antitumor effects of interferon and poly ICLC, and their possible utility as anti-neoplastic agents in man. Tex Rep Biol Med (1983) 0.83
GRP receptors are present in non small cell lung cancer cells. J Cell Biochem Suppl (1996) 0.83
Clinical simulators: applications and implications for rural medical education. Rural Remote Health (2006) 0.83
An effective rabies treatment in exposed monkeys: a single dose of interferon inducer and vaccine. Bull World Health Organ (1979) 0.83
Assignment of a gene required for infection with endogenous baboon virus to human chromosome 19. Cytogenet Cell Genet (1978) 0.82
Postinfection therapy of arbovirus infections in mice. Antimicrob Agents Chemother (1989) 0.82
Interferon induction in primates by stabilized polyriboinosinic acid-polyribocytidylic acid: effect of component size. Infect Immun (1981) 0.82
Modified polyriboinosinic-polyribocytidylic acid complex: induction of serum interferon, fever, and hypotension in rabbits. Antimicrob Agents Chemother (1980) 0.82
Chlorite-oxidized amylose as an adjuvant for interferon production. Infect Immun (1973) 0.82
Immunochemotherapy for Leishmania donovani infection in golden hamsters: combinatorial action of poly ICLC plus L-arginine and sodium stibogluconate (Stibanate). J Interferon Cytokine Res (1999) 0.82
Induction of interferon in vivo and in vitro by polynucleotides and derivatives, and preparation of derivatives. Methods Enzymol (1981) 0.82
Evaluation of polyinosinic-polycytidylic and poly-L-lysine in metastatic breast cancer. Cancer Treat Rep (1986) 0.81
Purification of herpesvirus saimiri and properties of the viral DNA. Arch Virol (1975) 0.81
Immune modulating effects of poly ICLC. Ann N Y Acad Sci (1980) 0.81
Poly ICLC enhances the antimalarial activity of chloroquine against multidrug-resistant Plasmodium yoelii nigeriensis in mice. J Interferon Cytokine Res (1997) 0.80
Adjuvant effects of low doses of a nuclease-resistant derivative of polyinosinic acid . polycytidylic acid on antibody responses of monkeys to inactivated Venezuelan equine encephalomyelitis virus vaccine. Infect Immun (1979) 0.80
Poly ICLC inhibits Plasmodium cynomolgi B malaria infection in rhesus monkeys. J Interferon Cytokine Res (1996) 0.80
Killing of Leishmania donovani amastigotes by poly ICLC in hamsters. J Interferon Cytokine Res (1996) 0.80
Human small cell lung cancer cells produce brain natriuretic peptide. Oncology (1999) 0.80
Chlamydia trachomatis infections in infants. Mt Sinai J Med (1986) 0.80
Induction of interferon in vivo by polynucleotides. Tex Rep Biol Med (1977) 0.80
Purification and analysis of the purity of NADH. Clin Chem (1976) 0.79
Enhanced therapeutic efficacy of poly(ICLC) and ribavirin combinations against Rift Valley fever virus infection in mice. Antimicrob Agents Chemother (1987) 0.79
A comparison of interferon responses to poly ICLC in males and females. J Interferon Res (1985) 0.79
Response of mouse tumor to interferon inducer and radiation. Int J Radiat Oncol Biol Phys (1985) 0.79
Further studies on rabies postexposure prophylaxis in mice: a comparison of vaccine with interferon and vaccine. J Gen Virol (1979) 0.79
Radiation damage and the interferon system. Tex Rep Biol Med (1977) 0.79
Microprocessor-based weight shift monitors for paraplegic patients. Arch Phys Med Rehabil (1986) 0.79
Post-exposure prophylaxis of murine rabies with polyinosinic-polycytidylic acid and chlorite-oxidized amylose. Antimicrob Agents Chemother (1974) 0.78
Evaluation of a nuclease-resistant derivative of poly(I) . poly(C) [poly(ICLC)] as a radioprotective agent. Radiat Res (1979) 0.78
Cortisol induction by poly ICLC: implications for clinical trials of interferon. Ann Neurol (1988) 0.78
Poly(I,C)-LC as an interferon inducer in refractory multiple myeloma. J Biol Response Mod (1985) 0.78