Published in Sci Am on March 01, 1979
Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Am J Pathol (1993) 6.55
Intratumor microvessel density as a prognostic factor in cancer. Am J Pathol (1995) 4.37
MicroRNA miR-21 regulates the metastatic behavior of B16 melanoma cells. J Biol Chem (2011) 1.46
The curcumin analog EF24 targets NF-κB and miRNA-21, and has potent anticancer activity in vitro and in vivo. PLoS One (2013) 1.03
New paradigm for vessel intravasation by tumor cells. Am J Pathol (2002) 0.98
Differences in lectin binding in tissue sections of human and murine malignant tumors and their metastases. Am J Pathol (1985) 0.89
The Type I IFN-Induced miRNA, miR-21. Pharmaceuticals (Basel) (2015) 0.77
Enhanced metastasis in RNF13 knockout mice is mediated by a reduction in GM-CSF levels. Protein Cell (2015) 0.75
The fluid mosaic model of the structure of cell membranes. Science (1972) 37.43
Transmembrane control of the receptors on normal and tumor cells. I. Cytoplasmic influence over surface components. Biochim Biophys Acta (1976) 5.63
The interactions of lectins with animal cell surfaces. Int Rev Cytol (1974) 5.02
The interaction of Ricinus communis agglutinin with normal and tumor cell surfaces. Biochim Biophys Acta (1972) 3.94
Ferritin-conjugated plant agglutinins as specific saccharide stains for electron microscopy: application to saccharides bound to cell membranes. Proc Natl Acad Sci U S A (1971) 3.90
Anionic sites of human erythrocyte membranes. II. Antispectrin-induced transmembrane aggregation of the binding sites for positively charged colloidal particles. J Cell Biol (1973) 3.76
Characterization of two plant lectins from Ricinus communis and their quantitative interaction with a murine lymphoma. Biochemistry (1974) 3.13
Trans-membrane control of the receptors on normal and tumor cells. II. Surface changes associated with transformation and malignancy. Biochim Biophys Acta (1976) 2.99
The localization of spectrin on the inner surface of human red blood cell membranes by ferritin-conjugated antibodies. J Cell Biol (1971) 2.96
A novel candidate metastasis-associated gene, mta1, differentially expressed in highly metastatic mammary adenocarcinoma cell lines. cDNA cloning, expression, and protein analyses. J Biol Chem (1994) 2.90
Temperature-dependent mobility of concanavalin A sites on tumour cell surfaces. Nat New Biol (1973) 2.56
Distribution of saccharide residues on membrane fragments from a myeloma-cell homogenate: its implications for membrane biogenesis. Proc Natl Acad Sci U S A (1972) 2.29
Local anesthetics affect transmembrane cytoskeletal control of mobility and distribution of cell surface receptors. Proc Natl Acad Sci U S A (1975) 2.26
Tumor cell instability, diversification, and progression to the metastatic phenotype: from oncogene to oncofetal expression. Cancer Res (1987) 2.24
Cancer metastasis. Organ colonization and the cell-surface properties of malignant cells. Biochim Biophys Acta (1982) 2.16
Organ selectivity for implantation survival and growth of B16 melanoma variant tumor lines. J Natl Cancer Inst (1976) 2.09
Topography of membrane concanavalin A sites modified by proteolysis. Nat New Biol (1972) 2.04
Specificity of arrest, survival, and growth of selected metastatic variant cell lines. Cancer Res (1978) 1.99
Ultrastructural localization of lectin-binding sites on the zonae pellucidae and plasma membranes of mammalian eggs. J Cell Biol (1975) 1.93
Development and biologic properties of malignant cell sublines and clones of a spontaneously metastasizing rat mammary adenocarcinoma. J Natl Cancer Inst (1982) 1.93
Identification, localization, and role of fibronectin in cultured bovine endothelial cells. Proc Natl Acad Sci U S A (1978) 1.89
Aglycosylantibody. Effects of exoglycosidase treatments on autochthonous antibody survival time in the circulation. J Biol Chem (1976) 1.77
Overexpression of the MTA1 gene in gastrointestinal carcinomas: correlation with invasion and metastasis. Int J Cancer (1997) 1.67
Arrest and metastasis of blood-borne tumor cells are modified by fusion of plasma membrane vesicles from highly metastatic cells. Proc Natl Acad Sci U S A (1980) 1.65
Anionic sites of human erythrocyte membranes. I. Effects of trypsin, phospholipase C, and pH on the topography of bound positively charged colloidal particles. J Cell Biol (1973) 1.65
Heparanases and tumor metastasis. J Cell Biochem (1988) 1.64
Heparan sulfate degradation: relation to tumor invasive and metastatic properties of mouse B16 melanoma sublines. Science (1983) 1.63
Metastatic melanoma cell heparanase. Characterization of heparan sulfate degradation fragments produced by B16 melanoma endoglucuronidase. J Biol Chem (1984) 1.61
Freeze-etch localization of concanavalin A receptors to the membrane intercalated particles of human erythrocyte ghost membranes. Biochim Biophys Acta (1974) 1.61
Quantitative two-dimensional ultrastructural distribution of Rh o (D) antigenic sites on human erythrocyte membranes. Proc Natl Acad Sci U S A (1971) 1.60
Activities of lectins and their immobilized derivatives in detergent solutions. Implications on the use of lectin affinity chromatography for the purification of membrane glycoproteins. Biochemistry (1977) 1.58
Interactions of tumor cells with vascular endothelial cell monolayers: a model for metastatic invasion. Proc Natl Acad Sci U S A (1979) 1.57
The cancer cell: dynamic aspects and modifications in cell-surface organization (first of two parts). N Engl J Med (1976) 1.51
The distribution and asymmetry of mammalian cell surface saccharides utilizing ferritin-conjugated plant agglutinins as specific saccharide stains. J Cell Biol (1974) 1.49
Ultrastructural analysis of toxin binding and entry into mammalian cells. Nature (1974) 1.48
Solubilization and degradation of subendothelial matrix glycoproteins and proteoglycans by metastatic tumor cells. J Biol Chem (1982) 1.48
Organ specificity of blood-borne tumour metastasis determined by cell adhesion? Nature (1975) 1.47
Degradation of basement membrane type IV collagen and lung subendothelial matrix by rat mammary adenocarcinoma cell clones of differing metastatic potentials. Cancer Res (1987) 1.42
c-erbB-2/neu overexpression enhances metastatic potential of human lung cancer cells by induction of metastasis-associated properties. Cancer Res (1994) 1.33
Cell surface molecules and tumor metastasis. Regulation of metastatic phenotypic diversity. Exp Cell Res (1984) 1.32
Lectin binding and perturbation of the outer surface of the cell membrane induces a transmembrane organizational alteration at the inner surface. Proc Natl Acad Sci U S A (1974) 1.30
Structure of the photosynthetic apparatus in protein-embedded chloroplasts. J Cell Biol (1971) 1.29
Differential expression of cell surface glycoproteins on various organ-derived microvascular endothelia and endothelial cell cultures. J Cell Physiol (1988) 1.27
Differential expression of annexin I in human mammary ductal epithelial cells in normal and benign and malignant breast tissues. Clin Exp Metastasis (1997) 1.26
Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro. Cancer Res (1996) 1.26
Phenotypic drift of metastatic and cell-surface properties of mammary adenocarcinoma cell clones during growth in vitro. Int J Cancer (1981) 1.26
Mechanism of cell entry and toxicity of an affinity- purified lectin from Ricinus communis and its differential effects on normal and virus-transformed fibroblasts. Cancer Res (1975) 1.25
Purification of cell membrane glycoproteins by lectin affinity chromatography. Biochim Biophys Acta (1979) 1.24
Differences in transferrin response and numbers of transferrin receptors in rat and human mammary carcinoma lines of different metastatic potentials. J Cell Physiol (1993) 1.23
Overexpression of metastasis-associated MTA1 mRNA in invasive oesophageal carcinomas. Br J Cancer (1999) 1.21
Molecular analysis of a candidate metastasis-associated gene, MTA1: possible interaction with histone deacetylase 1. J Exp Clin Cancer Res (2000) 1.21
Selection and biologic properties of malignant variants of a murine lymphosarcoma. J Natl Cancer Inst (1978) 1.21
Separable growth and migration factors for large-cell lymphoma cells secreted by microvascular endothelial cells derived from target organs for metastasis. Br J Cancer (1992) 1.21
Effects of chemotherapeutic drugs on platelet and metastatic tumor cell-endothelial cell interactions as a model for assessing vascular endothelial integrity. Cancer Res (1985) 1.20
Metastatic tumor cells adhere preferentially to the extracellular matrix underlying vascular endothelial cells. Int J Cancer (1980) 1.20
Serum and plasma M(r) 92,000 progelatinase levels correlate with spontaneous metastasis of rat 13762NF mammary adenocarcinoma. Cancer Res (1993) 1.19
Composition of the sulfur particle of Chromatium vinosum strain D. J Bacteriol (1971) 1.18
Organ-derived microvessel endothelial cells exhibit differential responsiveness to thrombin and other growth factors. Microvasc Res (1992) 1.18
Inhibitory effects of retinoic acid or retinyl acetate on the growth of untransformed, transformed, and tumor cells in vitro. J Natl Cancer Inst (1977) 1.18
Neuraminidase "unmasking" and failure of trypsin to "unmask" -D-galactose-like sites on erythrocyte, lymphoma, and normal and virus-transformed fibroblast cell membranes. J Natl Cancer Inst (1973) 1.17
Expression and localization of urokinase-type plasminogen activator in human astrocytomas in vivo. Cancer Res (1994) 1.16
Structure of the Chromatium sulfur particle and its protein membrane. J Bacteriol (1971) 1.16
Mobility and the restriction of mobility of plasma membrane lectin-binding components. Science (1974) 1.15
Mast cells and matrix degradation at sites of tumour invasion in rat mammary adenocarcinoma. Br J Cancer (1986) 1.15
Effects of local anesthetics on cell morphology and membrane-associated cytoskeletal organization in BALB/3T3 cells. J Cell Biol (1976) 1.15
The two-dimensional topographic distribution of H-2 histocompatibility alloantigens on mouse red blood cell membranes. J Cell Biol (1971) 1.14
The reducing potential of the bacterial photosynthetic reaction center. Photochem Photobiol (1969) 1.14
Cell surface glycoproteins of 13762NF mammary adenocarcinoma clones of differing metastatic potentials. Exp Cell Res (1983) 1.14
Role and regulation of expression of 92-kDa type-IV collagenase (MMP-9) in 2 invasive squamous-cell-carcinoma cell lines of the oral cavity. Int J Cancer (1993) 1.13
Expression and localization of urokinase-type plasminogen activator receptor in human gliomas. Cancer Res (1994) 1.13
Immunoaffinity isolation of membrane antigens with biotinylated monoclonal antibodies and streptavidin-agarose. Methods Enzymol (1986) 1.12
Metastatic tumor cell attachment and invasion assay utilizing vascular endothelial cell monolayers. J Histochem Cytochem (1982) 1.12
Qualitative and quantitative interactions of lectins with untreated and neuraminidase-treated normal, wild-type, and temperature-sensitive polyoma-transformed fibroblasts. Biochemistry (1975) 1.12
Molecular basis of tumor progression: mechanisms of organ-specific tumor metastasis. Semin Surg Oncol (1993) 1.11
Selection and in vivo properties of lectin-attachment variants of malignant murine lymphosarcoma cell lines. J Natl Cancer Inst (1980) 1.11
Expression of galectins on microvessel endothelial cells and their involvement in tumour cell adhesion. Glycoconj J (1994) 1.10
Effects of tunicamycin on B16 metastatic melanoma cell surface glycoproteins and blood-borne arrest and survival properties. Cancer Res (1981) 1.09
Expression and localization of 92 kDa type IV collagenase/gelatinase B (MMP-9) in human gliomas. Clin Exp Metastasis (1996) 1.09
Cell surface molecules and their prognostic values in assessing colorectal carcinomas. Ann Surg (2000) 1.08
Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo. Clin Exp Metastasis (1996) 1.08
The distribution of negative surface charges on mammalian spermatozoa. Am J Anat (1972) 1.08
Malignant melanoma cell lines selected in vitro for increased homotypic adhesion properties have increased experimental metastatic potential. Clin Exp Metastasis (1987) 1.07
Immunoaffinity isolation of membrane antigens with biotinylated monoclonal antibodies and immobilized streptavidin matrices. J Immunol Methods (1984) 1.07
Human heparanase: a molecular determinant of brain metastasis. Adv Enzyme Regul (2001) 1.06
Tumor cell adhesion under hydrodynamic conditions of fluid flow. APMIS (2001) 1.05
Expression of tissue inhibitors of metalloproteinases: negative regulators of human glioblastoma invasion in vivo. Clin Exp Metastasis (1995) 1.05
Tumor implantation and invasion at metastatic sites. Int Rev Exp Pathol (1983) 1.04
Extracellular annexin II is associated with divalent cation-dependent tumor cell-endothelial cell adhesion of metastatic RAW117 large-cell lymphoma cells. J Cell Biochem (1993) 1.04
Tumor metastasis-associated human MTA1 gene: its deduced protein sequence, localization, and association with breast cancer cell proliferation using antisense phosphorothioate oligonucleotides. J Cell Biochem (2000) 1.04
Candidate metastasis-associated genes of the rat 13762NF mammary adenocarcinoma. Breast Cancer Res Treat (1993) 1.04
Generation of phenotypic diversity and progression in metastatic tumor cells. Cancer Metastasis Rev (1984) 1.04
Determination of adhesive properties of variant metastatic melanoma cells to BALB/3T3 cells and their virus-transformed derivatives by a monolayer attachment assay. J Natl Cancer Inst (1976) 1.03
Increased content of an endogenous lactose-binding lectin in human colorectal carcinoma progressed to metastatic stages. Cancer Res (1991) 1.03
Distribution of fibronectin on clonal cell lines of a rat mammary adenocarcinoma growing in vitro and in vivo at primary and metastatic sites. Cancer Res (1981) 1.02
Overexpression and localization of cathepsin B during the progression of human gliomas. Clin Exp Metastasis (1995) 1.01
Fate of recirculating B16 melanoma metastatic variant cells in parabiotic syngeneic recipients. J Natl Cancer Inst (1977) 1.01
Clonal drift of cell surface, melanogenic, and experimental metastatic properties of in vivo-selected, brain meninges-colonizing murine B16 melanoma. Cancer Res (1982) 1.01
Organ specificity of metastatic tumor colonization is related to organ-selective growth properties of malignant cells. Int J Cancer (1986) 1.01
Comparison of 'spontaneous' and 'experimental' metastasis using rat 13762 mammary adenocarcinoma metastatic cell clones. Invasion Metastasis (1983) 1.00