Published in Gut on November 01, 1972
Migration of glycoprotein from the Golgi apparatus to the surface of various cell types as shown by radioautography after labelled fucose injection into rats. J Cell Biol (1974) 1.68
Breast liver metastases--incidence, diagnosis and outcome. J R Soc Med (1991) 1.42
Serum alkaline phosphatase levels in healthy children and evaluation of alkaline phosphatase z-scores in different types of rickets. J Clin Res Pediatr Endocrinol (2011) 1.19
Intestinal alkaline phosphatase in the diagnosis of liver disease. Gut (1977) 1.04
Polyacrylamide gel disc electrophoresis of alkaline phosphatase isoenzymes in bone and liver disease. J Clin Pathol (1976) 0.93
Studies on the frequency and pathogenesis of liver involvement in rheumatoid arthritis. Ann Rheum Dis (1979) 0.91
Intestinal alkaline phosphatase in bile: evidence for an enterohepatic circulation. Gut (1981) 0.85
Deoxycholate depresses small-intestinal enzyme activity. Gut (1975) 0.84
Cell-Penetrating, Guanidinium-Rich Oligophosphoesters: Effective and Versatile Molecular Transporters for Drug and Probe Delivery. J Am Chem Soc (2016) 0.82
Repeated serum alkaline phosphatase measurements in the treatment of childhood acute bone and joint infections with high doses of antibiotics. Ann Lab Med (2013) 0.79
The action of secretin and pancreozymin on small-intestinal alkaline phosphatase. Gut (1974) 0.77
The difference in serum alkaline phosphatase levels between girls with precocious puberty and those with normal puberty. Ann Pediatr Endocrinol Metab (2013) 0.75
Comparison of Salivary pH, Buffering Capacity and Alkaline Phosphatase in Smokers and Healthy Non-Smokers: Retrospective cohort study. Sultan Qaboos Univ Med J (2016) 0.75
Revisiting the single cell protein application of Cupriavidus necator H16 and recovering bioplastic granules simultaneously. PLoS One (2013) 0.75
The Possible Significance of Hexosephosphoric Esters in Ossification: Part II. The Phosphoric Esterase of Ossifying Cartilage. Biochem J (1924) 102.24
The Possible Significance of Hexosephosphoric Esters in Ossification. Biochem J (1923) 75.39
Influence of inorganic phosphate in the formation of phosphatases by Escherichia coli. Biochim Biophys Acta (1960) 14.35
The Possible Significance of Hexosephosphoric Esters in Ossification: Part V. The Enzyme in the Early Stages of Bone Development. Biochem J (1924) 13.10
Specific carcinoembryonic antigens of the human digestive system. J Exp Med (1965) 9.96
Calcification of hypertrophic cartilage in vitro. Biochem J (1934) 7.15
The possible significance of hexosephosphoric esters in ossification: Calcification in vitro. Biochem J (1930) 6.09
Disturbance of calcium metabolism by anticonvulsant drugs. Br Med J (1970) 5.81
ACRYLAMIDE GEL ELECTROPHORESIS. Ann N Y Acad Sci (1964) 5.09
A possible negative feedback phenomenon controlling formation of alkaline phosphomonoesterase in Escherichia coli. Nature (1959) 4.92
Enzymatic breakage and joining of deoxyribonucleic acid. V. End group labeling and analysis of deoxyribonucleic acid containing single straned breaks. J Biol Chem (1968) 4.65
GENETIC VARIATIONS OF HUMAN SERUM PHOSPHATASES. Acta Genet Stat Med (1963) 2.36
Serum alkaline phosphatase activity in diseases of the skeletal and hepatobiliary systems. A consideration of the current status. Am J Med (1959) 2.25
Electrophoretic separation of tissue-specific serum alkaline phosphatases. J Clin Pathol (1970) 2.22
Studies on calf-intestinal alkaline phosphatase. I. Chromatographic purification, microheterogeneity and some other properties of the purified enzyme. Biochim Biophys Acta (1961) 2.18
Alkaline phosphatase of Escherichia coli: a zinc metalloenzyme. Biochemistry (1962) 2.11
Iso-enzymes of alkaline phosphatase. Clin Chim Acta (1962) 2.06
Human alkaline phosphatase. Immunochemical identification of organ-specific isoenzymes. J Biol Chem (1968) 2.06
Some properties of alkaline phosphatase of cow's milk and calf intestinal mucosa. Biochem J (1955) 1.96
Purification and properties of molecular-weight variants of human placental alkaline phosphatase. Biochem J (1968) 1.93
The kinetics of hydrolysis of phenyl phosphate by alkaline phosphatases. Biochem J (1957) 1.91
Preparation and properties of highly purified alkaline phosphatase from swine kidneys. J Biol Chem (1958) 1.89
Immunology and biochemistry of Regan isoenzyme of alkaline phosphatase in human cancer. Nature (1968) 1.89
Alkaline Phosphatase in Human Sera and Placentae: Starch gel electrophoresis reveals many phosphatase components including a polymorphism in placentae. Science (1961) 1.84
A serum alkaline phosphatase isoenzyme of human neoplastic cell origin. Cancer Res (1968) 1.80
Serum biochemical values in rheumatoid disease. Ann Rheum Dis (1971) 1.77
L-phenylalanine: an organ specific, stereospecific inhibitor of human intestinal alkaline phosphatase. Nature (1963) 1.70
DIFFERENTIAL ACTION OF NEURAMINIDASE ON HUMAN SERUM ALKALINE PHOSPHATASES. Nature (1964) 1.69
Separation of human tissue alkaline phosphatases by electrophoresis on acrylamide disc gels. Clin Chim Acta (1968) 1.66
HEAT STABILITY OF HUMAN PLACENTAL ALKALINE PHOSPHATASE. J Clin Pathol (1965) 1.64
Pyrophosphate and diphosphonates in calcium metabolism and their possible role in renal failure. Arch Intern Med (1969) 1.64
Studies on alkaline phosphatase. Inhibition by phosphate derivatives and the substrate specificity. Biochem J (1967) 1.61
Ectopic production of an alkaline phosphatase isoenzyme in patients with cancer. N Engl J Med (1969) 1.55
SERUM-ALKALINE-PHOSPHATASE AND THE ABO BLOOD-GROUPS. Lancet (1965) 1.54
Alkaline phosphatase. Ann Intern Med (1967) 1.54
HEAT INACTIVATION IN THE STUDY OF HUMAN ALKALINE PHOSPHATASES. Ann Intern Med (1965) 1.49
Induction of intestinal brush border alkaline phosphatase by vitamin D and identity with ca-ATPase. Nature (1970) 1.48
Induction of rat liver alkaline phosphatase: the mechanism of the serum elevation in bile duct obstruction. J Clin Invest (1970) 1.45
Action of neuraminidase on human kidney alkaline phosphatase. Nature (1966) 1.45
Influence of diet on the "intestinal" component of serum alkaline phosphatase in people of different ABO blood groups and secretor status. Nature (1966) 1.44
Hydrolysis of nucleoside diand triphosphates by crystalline preparations of yeast inorganic pyrophosphatase. Biochim Biophys Acta (1960) 1.36
Detection of vitamin-d deficiency after partial gastrectomy. Lancet (1966) 1.35
Search for osteomalacia in 1228 patients after gastrectomy and other operations on the stomach. Lancet (1965) 1.35
Plasma-alkaline-phosphatase in normal adults and in patients with primary hyperparathyroidism. Lancet (1962) 1.33
Zone electrophoretic studies of serum alkaline phosphatase. J Clin Invest (1959) 1.32
Separation of alkaline phosphatase enzymes in human serum using gel-filtration (Sephadex G-200) techniques. Cancer (1967) 1.31
Human organ alkaline phosphatases: discrimination by several means including starch gel electrophoresis of antienzyme-enzyme supernatant fluids. Ann N Y Acad Sci (1963) 1.30
[DETECTION OF EMBRYO-SPECIFIC ALPHA-GLOBULIN IN THE BLOOD SERUM OF A PATIENT WITH PRIMARY LIVER CANCER]. Vopr Med Khim (1965) 1.28
Influence of reagents reacting with metal, thiol and amino sites of catalytic activity and l-phenylalanine inhibition of rat intestinal alkaline phosphatase. Biochem J (1967) 1.28
ASSOCIATIONS BETWEEN HUMAN SERUM ALKALINE PHOSPHATASES AND BLOOD GROUPS. Acta Genet Stat Med (1964) 1.26
Differentiation into three fractions of the serum alkaline phosphatase and the behavior of the fractions in diseases of bone and liver. Scand J Clin Lab Invest (1959) 1.24
Jaundice. Br Med J (1962) 1.23
Serum alkaline phosphatase fractions in hepato-biliary and bone diseases. Clin Sci (1962) 1.23
The presence of spingomyelin- and ceramide-cleaving enzymes in the small intestinal tract. Biochim Biophys Acta (1969) 1.23
The separation and detection of serum enzymes by paper electrophoresis. Scand J Clin Lab Invest (1954) 1.22
The behavior of infused human placental alkaline phosphatase in human subjects. J Lab Clin Med (1965) 1.22
The origin of elevation of serum alkaline phosphatase in hepatic disease. An experimental study. Gastroenterology (1962) 1.22
Studies on the mechanism of action of calciferol. 3. Vitamin D-mediated increase of intestinal brush order alkaline phosphatase activity. Biochim Biophys Acta (1970) 1.20
The functional differentiation of the small intestine. VIII. Regional differences in the alkaline phosphatases of the small intestine of the mouse from birth to one year. Dev Biol (1961) 1.15
Properties of alkaline-phosphatase fractions separated by starch-gel electrophoresis. Biochem J (1962) 1.14
FURTHER STUDIES ON THE ASSOCIATION BETWEEN HUMAN SERUM PHOSPHATASES AND BLOOD GROUPS. Acta Genet Stat Med (1963) 1.11
The differentiation of alkaline phosphatase in the small intestine. Ann N Y Acad Sci (1969) 1.10
Human placental alkaline phosphatase: molecular weight and subunit structure. Biochim Biophys Acta (1968) 1.10
Fine structural demonstration of phosphatase activity at pH 9. Nature (1965) 1.10
HISTOCHEMICAL LOCALIZATION OF ENZYME ACTIVITY IN THE KIDNEYS OF THREE MAMMALIAN SPECIES DURING THEIR POSTNATAL DEVELOPMENT. J Histochem Cytochem (1965) 1.09
THE AMINO ACID SEQUENCE OF A TETRADECAPEPTIDE CONTAINING THE REACTIVE SERINE IN E. COLI ALKALINE PHOSPHATASE. Proc Natl Acad Sci U S A (1963) 1.06
GENETIC STUDIES OF BLOOD GROUP-ASSOCIATED VARIATIONS IN A HUMAN SERUM ALKALINE PHOSPHATASE. Am J Hum Genet (1965) 1.06
HETEROGENEITY OF HUMAN INTESTINAL ALKALINE PHOSPHATASE. Nature (1963) 1.06
THE MECHANISM OF THE ELEVATION OF SERUM ALKALINE PHOSPHATASE IN PREGNANCY. J Obstet Gynaecol Br Commonw (1964) 1.05
SOURCE OF THE ELEVATED SERUM ALKALINE PHOSPHATASE ACTIVITY IN BILIARY OBSTRUCTION: STUDIES UTILIZING ISOLATED LIVER PERFUSION. Gastroenterology (1964) 1.04
Changes in blood chemistry associated with carcinoma metastic to bone. Cancer (1953) 1.03
[Kinetic study of the mechanism of catalytic action of Escherichia coli alkaline phosphatase]. Biochim Biophys Acta (1966) 1.02
Human placental alkaline phosphatase; a sialoprotein. Enzymologia (1967) 1.02
Separation of human serum-alkaline-phosphatase isoenzymes by polyacrylamide gel electrophoresis. Lancet (1969) 1.02
STUDIES ON BOVINE-LIVER ALKALINE PHOSPHATASE, PURIFICATION, PHOSPHATE INCORPORATION. Biochim Biophys Acta (1964) 1.01
Absence of phosphatase repression by inorganic phosphate in some micro-organisms. Nature (1961) 1.00
Increased lymph alkaline phosphatase after fat feeding: effects of medium chain triglycerides and inhibition of protein synthesis. Biochim Biophys Acta (1970) 0.99
Studies on calf-intestinal alkaline phosphatase. II. Incorporation of inorganic phosphate into a highly purified enzyme preparation. Biochim Biophys Acta (1961) 0.98
Distribution of alkaline phosphatase in serum protein fractions. J Clin Pathol (1962) 0.98
Urea as a selective inhibitor of human tissue alkaline phosphatases. Clin Chim Acta (1967) 0.97
Steatorrhoea with striking increase of plasma-alkaline-phosphatase of intestinal origin. Lancet (1968) 0.97
Enrichment and separation of alkaline phosphatase activities of human tissues by chromatography on cellulose ion-exchange adsorbents. Arch Biochem Biophys (1961) 0.97
Use of urea denaturation in the identification of human alkaline phosphatases. J Lab Clin Med (1968) 0.95
An histologic and histochemical study of familial osteoectasia. (Chronic idiopathic hyperphosphatasia). Am J Pathol (1966) 0.95
Alkaline-phosphatase-secreting tumour of lung. Lancet (1968) 0.93
Action of urea on human alkaline phosphatases: with a description of some automated techniques for the study of enzyme kinetics. Arch Biochem Biophys (1967) 0.92
THE METAL ION ACTIVATION OF THE ALKALINE BETA-GLYCEROPHOSPHATASE OF RABBIT SMALL INTESTINE. Biochem J (1965) 0.91
The phosphotransferase activity of phosphatases. 2. Studies with purified alkaline phosphomonoesterases and some substrate-specific phosphatases. Biochem J (1958) 0.90
THE ALKALINE PHOSPHATASE FRACTIONS OF HUMAN LYMPH. Clin Sci (1964) 0.90
Purification and molecular properties of placental and intestinal alkaline phosphatases. Ann N Y Acad Sci (1969) 0.89
Intestinal alkaline phosphatase in human lymph and serum. Scand J Clin Lab Invest (1966) 0.89
Alkaline phosphatase in duodenal juice following secretin and pancreozymin. Gut (1969) 0.88
Diminished oleic acid absorption in man by L-phenylalanine inhibition of an intestinal phosphohydrolase. Nat New Biol (1971) 0.88
THE AMINO ACID SEQUENCE AROUND THE REACTIVE SERINE IN CALF-INTESTINAL ALKALINE PHOSPHATASE. Biochim Biophys Acta (1964) 0.88
Kinetics of placental alkaline phosphatase. Biochim Biophys Acta (1960) 0.88
ISO-ENZYME PATTERNS OF SERUM ALKALINE PHOSPHATASE IN AGAR-GEL ELECTROPHORESIS AND THEIR CLINICAL SIGNIFICANCE. Clin Chim Acta (1963) 0.88
ALKALINE PHOSPHATASE ACTIVITY IN HUMAN THORACIC DUCT LYMPH. Acta Chir Scand (1965) 0.87
Alkaline phosphatase in meningiomas. Cancer (1970) 0.86
The effects of experimental acute biliary obstruction and release on the rat liver. A histochemical study. Am J Pathol (1962) 0.85
Collagen fiber formation and alkaline phosphatase. Arch Biochem Biophys (1951) 0.84
Primary biliary cirrhosis: how should we evaluate new treatments? Lancet (1994) 2.05
Severe Gardner syndrome in families with mutations restricted to a specific region of the APC gene. Am J Hum Genet (1995) 1.37
Evaluation of the efficacy and safety of rifaximin in the treatment of hepatic encephalopathy: a double-blind, randomized, dose-finding multi-centre study. Eur J Gastroenterol Hepatol (2000) 1.24
Intestinal alkaline phosphatase in the diagnosis of liver disease. Gut (1977) 1.04
Type III procollagen peptide: a marker of disease activity and prognosis in primary biliary cirrhosis. Lancet (1988) 0.98
Nodular regenerative hyperplasia of the liver, CREST syndrome and primary biliary cirrhosis: an overlap syndrome? Gut (1989) 0.98
Retinopathy of Waldenström's macroglobulinemia: photographic assessment. Am J Ophthalmol (1968) 0.96
Polyacrylamide gel disc electrophoresis of alkaline phosphatase isoenzymes in bone and liver disease. J Clin Pathol (1976) 0.93
Serum type III procollagen peptide, dynamic liver function tests and hepatic fibrosis in psoriatic patients receiving methotrexate. Br J Dermatol (1990) 0.91
Studies on the frequency and pathogenesis of liver involvement in rheumatoid arthritis. Ann Rheum Dis (1979) 0.91
High incidence of poor sulfoxidation in patients with primary biliary cirrhosis. N Engl J Med (1988) 0.90
Alkaline phosphatase in duodenal juice following secretin and pancreozymin. Gut (1969) 0.88
Non-cirrhotic portal hypertension with hypoxaemia. Gut (1988) 0.88
IgA nephropathy in non-cirrhotic portal hypertension. Gut (1991) 0.88
Localisation and semiquantitative assessment of hepatic procollagen mRNA in primary biliary cirrhosis. Gut (1998) 0.87
Androgen associated hepatocellular carcinoma with an aggressive course. Gut (1991) 0.87
Portal hypertension and ascites in systemic mastocytosis. Postgrad Med J (1989) 0.87
Antioxidant properties of colchicine in acute carbon tetrachloride induced rat liver injury and its role in the resolution of established cirrhosis. Biochim Biophys Acta (2000) 0.87
Alkaline phosphatase in meningiomas. Cancer (1970) 0.86
Vitamin D deficiency, osteomalacia, and primary biliary cirrhosis. Response to orally administered vitamin D3. Dig Dis Sci (1983) 0.86
Intestinal alkaline phosphatase in bile: evidence for an enterohepatic circulation. Gut (1981) 0.85
Endothelial cell transformation in primary biliary cirrhosis: a morphological and biochemical study. Hepatology (1990) 0.83
Serum type III procollagen aminopeptide for assessing liver damage in methotrexate-treated psoriatic patients. Br J Dermatol (1996) 0.82
The histopathological features of asymptomatic hepatitis C virus-antibody positive blood donors. Histopathology (1994) 0.82
Pancreatic alkaline phosphatase and a tumour variant. Gut (1972) 0.82
Hepatitis C-related chronic liver disease among asymptomatic blood donors in the north west of England. J Infect (1995) 0.81
Histochemical studies on pancreatic alkaline phosphatase. J Anat (1970) 0.80
Indian childhood cirrhosis in the United Kingdom. Gut (1980) 0.79
A multicentre, randomized study to evaluate the safety and efficacy of histamine dihydrochloride and interferon-alpha-2b for the treatment of chronic hepatitis C. J Viral Hepat (2002) 0.79
Chylous reflux into abdominal skin simulating lymphangioma circumscriptum in a patient with primary intestinal lymphangiectasia. Clin Exp Dermatol (1991) 0.79
Hypophosphataemia in acute liver failure. Br Med J (Clin Res Ed) (1987) 0.78
Tumour markers in diagnosis and management. Baillieres Clin Gastroenterol (1987) 0.78
The action of secretin and pancreozymin on small-intestinal alkaline phosphatase. Gut (1974) 0.77
Hepatitis C virus in autoimmune liver disease in the UK: aetiological agent or artefact? Gut (1994) 0.76
Metabolism of vitamin D in patients with primary biliary cirrhosis and alcoholic liver disease. Clin Sci (Lond) (1985) 0.76
Small-bowel volvulus in association with progressive systemic sclerosis. Br Med J (1979) 0.75
Hepatic granulomata associated with adenocarcinoma. Postgrad Med J (1983) 0.75
Primary biliary cirrhosis after benoxaprofen. Br Med J (Clin Res Ed) (1986) 0.75
Treatment of primary biliary cirrhosis. Br Med J (Clin Res Ed) (1987) 0.75
Cirrhosis in the North Western Region. Br Med J (Clin Res Ed) (1981) 0.75
Pre-medication for endoscopy. A trial of atropine, pentazocine or pethidine as a supplement to diazepam. Scand J Gastroenterol (1978) 0.75
Another treatment for primary biliary cirrhosis. Gastroenterology (1987) 0.75
Profound hypoglycaemia induced by propranolol in a patient with hepatic cirrhosis and severe hyperandrogenaemia. Ann Clin Biochem (1995) 0.75
Hepatic sarcoidosis and renal carcinoma. J Clin Gastroenterol (1999) 0.75
Investigation of the jaundiced patient. Br J Hosp Med (1982) 0.75
A new look at cirrhosis. J R Coll Physicians Lond (1982) 0.75
Liver disease in haemophiliacs: an overstated problem? Br J Haematol (1983) 0.75
Alkaline phosphatase in meningiomas. J Pathol (1970) 0.75
Raised liver enzymes in asymptomatic patients: investigation and outcome. Dig Dis (1992) 0.75
Serum alkaline phosphatase isoenzymes in liver disease. Gut (1972) 0.75
Treatment of primary biliary cirrhosis. Semin Liver Dis (1985) 0.75
The use of TIPS to control bleeding caput medusae. Br J Radiol (1998) 0.75
Nodular hyperplasia of the liver in primary biliary cirrhosis of early histological stages. Am J Gastroenterol (1987) 0.75