Published in Biochim Biophys Acta on April 21, 1973
Feedback regulation in the lactose operon: a mathematical modeling study and comparison with experimental data. Biophys J (2003) 2.01
Polypeptide-chain-elongation rate in Escherichia coli B/r as a function of growth rate. Biochem J (1976) 1.67
Synthesis time of beta-galactosidase in Escherichia coli B/r as a function of growth rate. Biochem J (1975) 1.37
Lactose transport coupled to proton movements in Escherichia coli. Biochem Biophys Res Commun (1970) 3.32
Proton/sodium ion antiport in Escherichia coli. Biochem J (1974) 2.89
Stoicheiometry of lactose-H+ symport across the plasma membrane of Escherichia coli. Biochem J (1973) 2.57
Turnover numbers of membrane carriers and the action of polypeptide antibiotics. Nature (1968) 2.10
The substrate-facilitated transport of the glucose carrier across the human erythrocyte membrane. Biochim Biophys Acta (1965) 2.05
From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance. Cell Mol Life Sci (2001) 1.89
Biological membranes behave as non-porous polymeric sheets with respect to the diffusion of non-electrolytes. Nature (1969) 1.69
The kinetic parameters of the monosaccharide transfer system of the human erythrocyte. Biochim Biophys Acta (1966) 1.52
Mathematical modelling of the chemotherapy of Plasmodium falciparum malaria with artesunate: postulation of 'dormancy', a partial cytostatic effect of the drug, and its implication for treatment regimens. Parasitology (2000) 1.50
Galactoside transport dissociated from proton movement in mutants of Escherichia coli. Biochem Biophys Res Commun (1973) 1.46
Testing and characterizing the simple carrier. Biochim Biophys Acta (1974) 1.44
The effect of membrane potential on the mammalian sodium-potassium pump reconstituted into phospholipid vesicles. J Physiol (1987) 1.42
The proton-translocating ATPase of Escherichia coli. FEBS Lett (1974) 1.41
Cotransport of salt and water in membrane proteins: membrane proteins as osmotic engines. J Membr Biol (1994) 1.40
Relation between the turnover number for vinblastine transport and for vinblastine-stimulated ATP hydrolysis by human P-glycoprotein. J Biol Chem (1997) 1.38
P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity. Proc Natl Acad Sci U S A (1997) 1.36
Carrier and non-carrier models for sugar transport in the human red blood cell. Biochim Biophys Acta (1972) 1.35
Mathematical modelling of the within-host dynamics of Plasmodium falciparum. Parasitology (2000) 1.33
Diffusion within egg lecithin bilayers resembles that within soft polymers. J Gen Physiol (1978) 1.32
Energy coupling in secondary active transport. Biochim Biophys Acta (1980) 1.31
An analysis of intestinal calcium transport across the rat intestine. Am J Physiol (1986) 1.26
Kinetic parameters of glucose efflux from human red blood cells under zero-trans conditions. Biochim Biophys Acta (1972) 1.25
Biophysical analysis of novel transport pathways induced in red blood cell membranes. J Membr Biol (1987) 1.21
Passive rubidium fluxes mediated by Na-K-ATPase reconstituted into phospholipid vesicles when ATP- and phosphate-free. J Physiol (1982) 1.20
Pharmacokinetic-pharmacodynamic modelling of the antimalarial activity of mefloquine. Parasitology (2001) 1.18
Structure-activity relationships of P-glycoprotein interacting drugs: kinetic characterization of their effects on ATPase activity. Biochim Biophys Acta (1997) 1.15
Modelling the chloroquine chemotherapy of falciparum malaria: the value of spacing a split dose. Parasitology (1998) 1.15
Mathematical modelling of malaria chemotherapy: combining artesunate and mefloquine. Parasitology (2002) 1.13
Co-operative, competitive and non-competitive interactions between modulators of P-glycoprotein. Biochim Biophys Acta (1996) 1.12
The transport of sugars. Br Med Bull (1968) 1.09
Quantitative predictions of a noncarrier model for glucose transport across the human red cell membrane. Biophys J (1970) 1.09
A 19-kDa C-terminal tryptic fragment of the alpha chain of Na/K-ATPase is essential for occlusion and transport of cations. Proc Natl Acad Sci U S A (1990) 1.08
Competitive, non-competitive and cooperative interactions between substrates of P-glycoprotein as measured by its ATPase activity. Biochim Biophys Acta (1997) 1.08
A modle for active transport of sodium and potassium ions as mediated by a tetrameric enzyme. Proc Natl Acad Sci U S A (1973) 1.08
Cation activation of the pig kidney sodium pump: transmembrane allosteric effects of sodium. J Physiol (1985) 1.04
Combined effects of ATP and phosphate on rubidium exchange mediated by Na-K-ATPase reconstituted into phospholipid vesicles. J Physiol (1982) 1.01
New theory for glucose transport across membranes. Nat New Biol (1971) 1.01
P-glycoprotein substrates and antagonists cluster into two distinct groups. Mol Pharmacol (1997) 0.99
The kinetics of the beta-galactoside-proton symport of Escherichia coli. Biochem J (1981) 0.98
Proton movements coupled to the transport of -galactosides into escherichia coli. Biochem J (1972) 0.98
The new permeability pathways induced by the malaria parasite in the membrane of the infected erythrocyte: comparison of results using different experimental techniques. J Membr Biol (2004) 0.97
Testing and characterizing the simple pore. Biochim Biophys Acta (1974) 0.97
Rejection criteria for the asymmetric carrier and their application to glucose transport in the human red blood cell. Biochim Biophys Acta (1972) 0.95
Effects of atp or phosphate on passive rubidium fluxes mediated by Na-K-ATPase reconstituted into phospholipid vesicles. J Physiol (1982) 0.95
Kinetic modelling of chloroquine uptake by malaria-infected erythrocytes. Assessment of the factors that may determine drug resistance. Biochem Pharmacol (1991) 0.95
A simple resolution of the kinetic anomaly in the exchange of different sugars across the membrane of the human red blood cell. Biochim Biophys Acta (1972) 0.94
When is the outer membrane of Escherichia coli rate-limiting for uptake of galactosides? J Theor Biol (1984) 0.93
Uptake of nucleosides in density-inhibited cultures of 3T3 cells. Nature (1977) 0.93
Kinetics of lactose transport into Escherichia coli in the presence and absence of a protonmotive force. FEBS Lett (1980) 0.93
Non-Stokesian nature of transverse diffusion within human red cell membranes. J Membr Biol (1986) 0.93
Proton translocation by cytochrome oxidase in (antimycin + myxothiazol)-treated rat liver mitochondria using ferrocyanide or hexammineruthenium as electron donor. Biochem J (1986) 0.92
Kinetic tests of models for sugar transport in human erythrocytes and a comparison of fresh and cold-stored cells. Biochim Biophys Acta (1983) 0.91
The kinetic dissection of transport from metabolic trapping during substrate uptake by intact cells. Uridine uptake by quiescent and serum-activated Nil 8 hamster cells and their murine sarcoma virus-transformed counterparts. Biochim Biophys Acta (1979) 0.90
The transport of steroids into animal cells in culture. Endocrinology (1981) 0.90
Protection of respiration of a crude mitochondrial preparation in cerebral ischaemia by control of blood glucose. J Neurol Neurosurg Psychiatry (1985) 0.90
Mutually co-operative interactions between modulators of P-glycoprotein. Biochim Biophys Acta (1997) 0.89
Analysis of MDR1 P-glycoprotein conformational changes in permeabilized cells using differential immunoreactivity. Biochemistry (2001) 0.89
Kinetic parameters for reversal of the multidrug pump as measured for drug accumulation and cell killing. Cancer Chemother Pharmacol (1996) 0.89
A mortalization theory for the control of the cell proliferation and for the origin of immortal cell lines. J Theor Biol (1979) 0.87
Targeted disruption of the mouse mdr1b gene reveals that steroid hormones enhance mdr gene expression. J Biol Chem (1993) 0.87
ATPase activity of P-glycoprotein related to emergence of drug resistance in Ehrlich ascites tumor cell lines. Biochim Biophys Acta (1997) 0.86
Identification of a component of a transport 'carrier' system: isolation of the permease expression of the LAC operon of Escherichia coli. Nature (1966) 0.86
New permeability pathways induced by the malarial parasite in the membrane of its host erythrocyte: potential routes for targeting of drugs into infected cells. Biosci Rep (1987) 0.86
Chemical modification of Glu-953 of the alpha chain of Na+,K(+)-ATPase associated with inactivation of cation occlusion. Proc Natl Acad Sci U S A (1992) 0.86
The location of CuA in mammalian cytochrome c oxidase. FEBS Lett (1988) 0.86
Zero-trans and infinite-cis uptake of galactose in human erythrocytes. Biochim Biophys Acta (1975) 0.85
Intrinsic, apparent, and effective affinities of co- and countertransport systems. Am J Physiol (1986) 0.85
Modulation of bone calcium-binding sites regulates plasma calcium: an hypothesis. Calcif Tissue Int (1992) 0.85
Kinetics of transport: analyzing, testing, and characterizing models using kinetic approaches. Methods Enzymol (1989) 0.84
Regulatin of uridine uptake by serum and insulin in density-inhibited 3T3 cells. Biochim Biophys Acta (1977) 0.84
The binding of cupric ions to bovine pancreatic ribonuclease studies with diligand metal-ion buffers. Biochem J (1967) 0.83
On the temperature dependence of initial velocities of glucose transport in the human red blood cell. Biochim Biophys Acta (1972) 0.83
Implications of two different types of diffusion for biological membranes. Nat New Biol (1971) 0.83
The efflux of sodium from human red blood cells. Biochim Biophys Acta (1973) 0.83
Chemiosmotic coupling in cytochrome oxidase. Possible protonmotive O loop and O cycle mechanisms. FEBS Lett (1985) 0.83
Structure of the cation binding sites of Na/K-ATPase. Soc Gen Physiol Ser (1991) 0.83
The transient kinetics of uptake of galactosides into Escherichia coli. Biochem J (1984) 0.82
Glucose-6-phosphate dehydrogenase: a candidate gene for diabetes. Diabet Med (2002) 0.82
The acridone derivative MBLI-87 sensitizes breast cancer resistance protein-expressing xenografts to irinotecan. Eur J Cancer (2011) 0.82
Isolation of a glucose-binding component from human erythrocyte membranes. Nature (1966) 0.82
CaBPr facilitates intracellular diffusion for Ca pumping in distal convoluted tubule. Am J Physiol (1988) 0.82
The influence of unstirred layers on the kinetics of carrier-mediated transport. J Theor Biol (1972) 0.81
A quantitative analysis of the aging of human glial cells in culture. J Cell Physiol (1983) 0.81
Biophysical analysis of a novel transport pathway induced in red blood cell membranes by the malaria parasite. Prog Clin Biol Res (1988) 0.80
Coordinate changes in drug resistance and drug-induced conformational transitions in altered-function mutants of the multidrug transporter P-glycoprotein. Biochemistry (2001) 0.80
Models for the active transport of cations...the steady-state analysis. Mol Cell Biochem (1977) 0.80
The isolation of a membrane-bound protein associated with the beta-galactoside-permease of Escherichia coli. Curr Mod Biol (1967) 0.79
Increase in the affinity of the uridine phosphorylation system for ATP after serum or insulin activation of 3T3 fibroblasts. J Supramol Struct (1978) 0.79
Temperature dependence of uridine transport in quiescent and serum-stimulated 3T3 cells. Biochim Biophys Acta (1976) 0.79
Uptake of cortisol by isolated rat liver cells. A phenomenon indicative of carrier-mediation and simple diffusion. Hoppe Seylers Z Physiol Chem (1976) 0.78
Measurement of the proton-motive stoichiometry of the respiratory chain of rat liver mitochondria: the effect of N-ethylmaleimide. Biochim Biophys Acta (1986) 0.78
Saturation reversal of the multidrug pump using many reversers in low-dose combinations. Anticancer Drugs (1995) 0.78
P-glycoprotein-mediated colchicine resistance in different cell lines correlates with the effects of colchicine on P-glycoprotein conformation. Biochemistry (2001) 0.78
Synergistic effect of prochlorperazine and dipyridamole on the cellular retention and cytotoxicity of doxorubicin. Clin Cancer Res (2000) 0.78
Stimulation of uridine uptake in 3T3 cells in associated with increased ATP affinity of uridine-phosphorylating system. Nature (1978) 0.77
Identification of the cation binding domain of Na/K-ATPase. Acta Physiol Scand Suppl (1992) 0.77
Analysis of calcium transport in rat intestine. Adv Exp Med Biol (1986) 0.77
Uridine transport properties of mammalian cell membranes are not directly involved with growth control or oncogenesis. FEBS Lett (1978) 0.77
Kinetics of in vitro ageing of mouse embryo fibroblasts. J Cell Sci (1984) 0.77
A possible role for the active-site thiol in lactose transport in Escherichia coli. Biochem Soc Trans (1980) 0.77