Published in J Reprod Fertil Suppl on December 01, 1973
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Sildenafil (Viagra) prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current. Circulation (2000) 1.91
Detection of respiratory syncytial virus in clinical specimens by viral culture, direct and indirect immunofluorescence, and enzyme immunoassay. J Clin Microbiol (1988) 1.88
Hydrophilicity/lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors. Trends Pharmacol Sci (1998) 1.78
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The L beta T2 clonal gonadotrope: a model for single cell studies of endocrine cell secretion. Endocrinology (1996) 1.27
Ovarian secretion of progesterone and 20-alpha-hydroxypregn-4-en-3-one during pseudopregnancy and pregnancy in rats. Endocrinology (1967) 1.26
Modifications in the CNS regulation of reproduction after exposure of prepubertal rats to steroid hormones. Recent Prog Horm Res (1966) 1.19
Nature of the clinical difficulties of first-year family medicine residents under direct observation. CMAJ (1992) 1.18
Timing of prenatal androgen exposure: anatomical and endocrine effects on juvenile male and female rhesus monkeys. Horm Behav (2000) 1.16
Latex immunoassay for rapid detection of rotavirus. J Clin Microbiol (1984) 1.14
Comparison of polymerase chain reaction assay with culture for detection of genital mycoplasmas in perinatal infections. Eur J Clin Microbiol Infect Dis (1998) 1.09
Significant interaction between the nonprescription antihistamine diphenhydramine and the CYP2D6 substrate metoprolol in healthy men with high or low CYP2D6 activity. Clin Pharmacol Ther (2000) 1.05
Suppression of spontaneous LH surges in estrogen-treated ovariectomized rats by microimplants of antiestrogens into the preoptic brain. Brain Res (1989) 1.04
Erythromycin blocks the rapid component of the delayed rectifier potassium current and lengthens repolarization of guinea pig ventricular myocytes. Circulation (1995) 1.02
The disposition of fluoxetine but not sertraline is altered in poor metabolizers of debrisoquin. Clin Pharmacol Ther (1996) 0.96
Influence of CYP2D6 activity on the disposition and cardiovascular toxicity of the antidepressant agent venlafaxine in humans. Pharmacogenetics (1999) 0.96
Viral isolation versus immune staining of infected cell cultures for the laboratory diagnosis of herpes simplex virus infections. J Clin Microbiol (1986) 0.95
Block of the rapid component of the delayed rectifier potassium current by the prokinetic agent cisapride underlies drug-related lengthening of the QT interval. Circulation (1998) 0.95
Combination of phenotype assessments and CYP2C9-VKORC1 polymorphisms in the determination of warfarin dose requirements in heavily medicated patients. Clin Pharmacol Ther (2007) 0.94
The role of catecholamines in the regulation of pituitary luteinizing hormone and follicle-stimulating hormone secretion. Endocr Rev (1982) 0.94
Thioridazine lengthens repolarization of cardiac ventricular myocytes by blocking the delayed rectifier potassium current. J Pharmacol Exp Ther (1999) 0.93
Droperidol lengthens cardiac repolarization due to block of the rapid component of the delayed rectifier potassium current. J Cardiovasc Electrophysiol (1999) 0.92
Effects of estradiol and progesterone on plasma gonadotropins, prolactin, and LHRH in specific brain areas of ovariectomized rats. Biol Reprod (1981) 0.91
Effect of low dose quinidine on encainide pharmacokinetics and pharmacodynamics. Influence of genetic polymorphism. J Pharmacol Exp Ther (1989) 0.91
Effect of gender, sex hormones, time variables and physiological urinary pH on apparent CYP2D6 activity as assessed by metabolic ratios of marker substrates. Pharmacogenetics (2000) 0.91
Angiotensin II modulates the delayed rectifier potassium current of guinea pig ventricular myocytes. Pflugers Arch (1994) 0.91
Effect of cigarette smoking on mexiletine kinetics. Clin Pharmacol Ther (1985) 0.90
Effects of age and sex on bone density in the rhesus monkey. Bone (1989) 0.89
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Right ventricular ejection fraction measurement: contrast ventriculography versus gated blood pool and gated first-pass radionuclide methods. Am J Cardiol (1984) 0.89
Role of glucocorticoids in the stress-induced suppression of testicular steroidogenesis in adult male rats. Horm Behav (1992) 0.88
Hypothalamic regulation of ovulation: effects of urethane and progesterone. Proc Soc Exp Biol Med (1968) 0.87
Role of specific cytochrome P450 enzymes in the N-oxidation of the antiarrhythmic agent mexiletine. Xenobiotica (2003) 0.87
Stereoselective disposition of mexiletine in man. Br J Clin Pharmacol (1986) 0.87
Beneficial effects of fish-oil supplements on lipids, lipoproteins, and lipoprotein lipase in patients with glycogen storage disease type I. Am J Clin Nutr (1993) 0.86
Positive and negative feedback effects of estrogen on pituitary LH synthesis and release in normal and androgen-sterilized rats. Endocrinology (1970) 0.85
Block of IKs by the diuretic agent indapamide modulates cardiac electrophysiological effects of the class III antiarrhythmic drug dl-sotalol. J Pharmacol Exp Ther (1997) 0.85
In vitro characterization of cytochrome P450 2D6 inhibition by classic histamine H1 receptor antagonists. Drug Metab Dispos (1998) 0.85
Clinical pharmacokinetics of mexiletine. Clin Pharmacokinet (1999) 0.85
Effects of cadmium and nisoldipine on the delayed rectifier potassium current in guinea pig ventricular myocytes. J Pharmacol Exp Ther (1997) 0.84
Effect of immobilization stress on plasma luteinizing hormone, testosterone, and corticosterone concentrations and on 3 beta-hydroxysteroid dehydrogenase activity in the testes of adult rats. Proc Soc Exp Biol Med (1993) 0.83
Effects of restraint stress on plasma LH and testosterone concentrations, Leydig cell LH/hCG receptors, and in vitro testicular steroidogenesis in adult rats. Horm Behav (1990) 0.83
Single cell levels of hypothalamic messenger ribonucleic acid encoding luteinizing hormone-releasing hormone in intact, castrated, and hyperprolactinemic male rats. Endocrinology (1991) 0.83
Hypothalamic peptide and catecholamine secretion: roles for portal and retrograde blood flow in the pituitary stalk in the release of hypothalamic dopamine and pituitary prolactin and LH. Clin Obstet Gynaecol (1978) 0.83
Diphenhydramine alters the disposition of venlafaxine through inhibition of CYP2D6 activity in humans. J Clin Psychopharmacol (2001) 0.83
Effects of estradiol and progesterone on catecholamine turnover rates in discrete hypothalamic regions in ovariectomized rats. Endocrinology (1981) 0.83
Medial preoptic microimplants of the antiestrogen, keoxifene, affect luteinizing hormone-releasing hormone mRNA levels, median eminence luteinizing hormone-releasing hormone concentrations and luteinizing hormone release in ovariectomized, estrogen-treated rats. J Neuroendocrinol (1989) 0.82
Comparison of electrostimulation methods for semen recovery in the rhesus monkey (Macaca mulatta). J Med Primatol (1988) 0.82
Hypothalamic regulation of pituitary FSH secretion. Endocrinology (1976) 0.82
Effects of neonatal testicular suppression with a GnRH antagonist on social behavior in group-living juvenile rhesus monkeys. Horm Behav (1995) 0.82
Blockade of neonatal activation of the pituitary-testicular axis with continuous administration of a gonadotropin-releasing hormone agonist in male rhesus monkeys. J Clin Endocrinol Metab (1984) 0.82
Suppression of the pituitary follicle-stimulating hormone secretion during proestrus and estrus in rats by porcine follicular fluid: possible site of action. Endocrinology (1979) 0.82
Dose dependent effects of progesterone on the facilitation and inhibition of spontaneous gonadotropin surges in estrogen treated ovariectomized rats. Biol Reprod (1979) 0.82
A prospective pilot study investigating the musculoskeletal pain in postmenopausal breast cancer patients receiving aromatase inhibitor therapy. Curr Oncol (2011) 0.82
Antide (Nal-Lys GnRH antagonist) suppression of pituitary-testicular function and sexual behavior in group-living rhesus monkeys. Physiol Behav (1991) 0.82
Qualitative research in family medicine. An inevitable development. Can Fam Physician (2000) 0.82
Catecholamine turnover rates in discrete hypothalamic areas and associated changes in median eminence luteinizing hormone-releasing hormone and serum gonadotropins on proestrus and diestrous day 1. Endocrinology (1981) 0.82
Effect of electrical stimulation of the preoptic area on plasma LH concentrations in proestrous rats. Endocrinology (1971) 0.81
Temporal interrelationships between plasma LH, ovarian secretion rates and peripheral plasma progestin concentrations in the rat: effects of Nembutal and exogenous gonadotropins. Endocrinology (1971) 0.81
Sexual conflict in Gerris gillettei (Insecta: Hemiptera): intraspecific intersexual correlated morphology and experimental assessment of behaviour and fitness. J Evol Biol (2011) 0.81
Estrogen inhibition of dopamine release into hypophysial portal blood. Endocrinology (1979) 0.81
Correlation of luteinizing hormone surges with estrogen nuclear and progestin cytosol receptors in the hypothalamus and pituitary gland. II. Temporal estradiol effects. Neuroendocrinology (1985) 0.81
Further evidence that luteinizing hormone-releasing hormone also is follicle-stimulating hormone-releasing hormone. Endocrinology (1979) 0.81
Triamterene inhibits the delayed rectifier potassium current (IK) in guinea pig ventricular myocytes. Circ Res (1994) 0.81
Negative feedback effects of progesterone correlated with changes in hypothalamic norepinephrine and dopamine turnover rates, median eminence luteinizing hormone-releasing hormone, and peripheral plasma gonadotropins. Endocrinology (1981) 0.81
Changes in tyrosine hydroxylase mRNA levels in medullary A1 and A2 neurons and locus coeruleus following castration and estrogen replacement in rats. Brain Res Mol Brain Res (1992) 0.81
Stereoselective high-performance liquid chromatographic assay for the determination of sotalol enantiomers in biological fluids. J Chromatogr (1993) 0.81
Carry-over effects in bioequivalence studies. J Biopharm Stat (2001) 0.81
Changes in peripheral plasma progesterone during the rat 4-day estrous cycle: an adrenal diurnal rhythm. Proc Soc Exp Biol Med (1973) 0.81
Stereoselective genetically-determined interaction between chronic flecainide and quinidine in patients with arrhythmias. Br J Clin Pharmacol (1992) 0.81
Secretion of dopamine into hypophysial portal blood by rats bearing prolactin-secreting tumors or ectopic pituitary glands. Endocrinology (1979) 0.80
Morphine amplifies norepinephrine (NE)-induced LH release but blocks NE-stimulated increases in LHRH mRNA levels: comparison of responses obtained in ovariectomized, estrogen-treated normal and androgen-sterilized rats. Brain Res Mol Brain Res (1993) 0.80
Changes in radioimmunoassayable luteinizing hormone-releasing hormone in discrete brain areas of the rat at various times on proestrus, diestrous day 1, and after phenobarbital administration. Endocrinology (1981) 0.80
A role for hypothalamic catecholamines in the regulation of gonadotropin secretion. Recent Prog Horm Res (1984) 0.80
N-methyl-D,L-aspartic acid differentially affects LH release and LHRH mRNA levels in estrogen-treated ovariectomized control and androgen-sterilized rats. Brain Res Mol Brain Res (1993) 0.80
Influence of continuous gonadotropin-releasing hormone (GnRH) agonist treatment on luteinizing hormone and testosterone secretion, the response to GnRH, and the testicular response to human chorionic gonadotropin in male rhesus monkeys. J Clin Endocrinol Metab (1984) 0.80
Treatment of endometriosis in monkeys: effectiveness of continuous infusion of a gonadotropin-releasing hormone agonist compared to treatment with a progestational steroid. J Clin Endocrinol Metab (1986) 0.80
Atherogenic, hemostatic, and other potential risk markers in subjects with previous isolated myocardial infarction compared with long-standing uncomplicated stable angina. Am Heart J (1998) 0.79
Pharmacokinetic and pharmacodynamic interaction between mexiletine and propafenone in human beings. Clin Pharmacol Ther (2000) 0.79
Adrenal gland involvement in synchronizing the preovulatory release of LH in rats. Proc Soc Exp Biol Med (1975) 0.79
Comparative efficacy of terbutaline sulphate delivered by Turbuhaler dry powder inhaler or pressurised metered dose inhaler with Nebuhaler spacer in children during an acute asthmatic episode. Arch Dis Child (2003) 0.79
Role of the preoptic brain in the regulation of preovulatory gonadotropin surges in the hamster. Exp Brain Res (1980) 0.79
CYP2D6 mutations and therapeutic outcome in schizophrenic patients. Pharmacotherapy (1999) 0.79
Temporal changes in tyrosine hydroxylase mRNA levels in A1, A2 and locus ceruleus neurons following electrical stimulation of A1 noradrenergic neurons. Brain Res Mol Brain Res (1992) 0.79
Block of potassium currents in guinea pig ventricular myocytes and lengthening of cardiac repolarization in man by the histamine H1 receptor antagonist diphenhydramine. J Pharmacol Exp Ther (1999) 0.79
Flecainide enantiomers: disposition in human subjects and electrophysiologic actions in vitro. Clin Pharmacol Ther (1989) 0.78
High-performance liquid chromatographic assay for mexiletine enantiomers in human plasma. J Chromatogr (1985) 0.78
Identification of the cytochrome P450 enzymes involved in the metabolism of domperidone. Xenobiotica (2005) 0.78
Interactions of the light-dark cycle, adrenal glands and time of steroid administration in determining the temporal sequence of LH and prolactin release in female rats. Endocrinology (1976) 0.78
Ovarian steroids modulate the release of dopamine into hypophysial portal blood and the density of anterior pituitary [3H]spiperone-binding sites in ovariectomized rats. Endocrinology (1984) 0.78
Study of the drug-drug interaction between simvastatin and cisapride in man. Eur J Clin Pharmacol (2001) 0.78
Effects of preoptic electrical stimulation on pituitary LH release following interruption of components of the preoptico-tuberal pathway in rats. Endocrinology (1973) 0.78
Hypersecretion of luteinizing hormone following ovariectomy and estrogen administration in rats bearing anterior pituitary transplants. Biol Reprod (1979) 0.78