Published in Clin Pharmacol Ther on August 01, 1974
The efficacy of intensive dietary therapy alone or combined with lovastatin in outpatients with hypercholesterolemia. N Engl J Med (1993) 4.61
Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens. Nature (1980) 2.85
Effect of environmental factors on drug metabolism: decreased plasma half-life of antipyrine in workers exposed to chlorinated hydrocarbon insecticides. Clin Pharmacol Ther (1969) 2.75
Drug treatment of dyslipidemias: practical guidelines for the primary care physician. Heart Dis Stroke (1994) 2.68
Fentanyl, fads, and folly: who will adopt the therapeutic orphans? J Pediatr (1991) 2.42
Response of hepatic microbodies to a hypolipidemic agent, ethyl chlorophenoxyisobutyrate (CPIB). J Cell Biol (1966) 2.29
A CLINICAL STUDY OF THE PLASMA VOLUME IN ACUTE INTESTINAL OBSTRUCTION. Ann Surg (1940) 2.22
The role of CTLA-4 in the regulation and initiation of T-cell responses. Immunol Rev (1996) 2.18
Drug-induced hypergastrinemia: absence of trophic effects on colonic carcinoma in rats. Gastroenterology (1995) 2.12
Is the "therapeutic orphan" about to be adopted? Pediatrics (1996) 2.05
Report of the Institute of Medicine Committee on the Efficacy and Safety of Halcion. Arch Gen Psychiatry (1999) 2.03
Helping Down Syndrome children to reach new heights: the role of the pediatric nurse. Pediatr Nurs (1992) 2.01
Drugs as etiologic factors in the Stevens-Johnson syndrome. Am J Med (1968) 1.98
The efficacy and six-week tolerability of simvastatin 80 and 160 mg/day. Am J Cardiol (1997) 1.98
Sulfonamide hepatic injury. Review of the literature and report of a case due to sulfamethoxazole. N Engl J Med (1967) 1.97
Plasma protein binding of tricyclic anti-depressants in man. Biochem Pharmacol (1969) 1.86
Developmental regulation of the expression of 72 and 92 kd type IV collagenases in human trophoblasts: a possible mechanism for control of trophoblast invasion. Am J Obstet Gynecol (1994) 1.71
Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: pooled analysis of two phase II studies. Clin Ther (2001) 1.65
Antacid therapy and drug kinetics. Clin Pharmacokinet (1977) 1.60
Young low responders protected from untoward effects of reduced ovarian response. Fertil Steril (1998) 1.57
Efficacy and safety of simvastatin 80 mg/day in hypercholesterolemic patients. The Expanded Dose Simvastatin U.S. Study Group. Am J Cardiol (1998) 1.56
The molecular basis of partial penetrance of splicing mutations in cystic fibrosis. Am J Hum Genet (1997) 1.56
Pharmacokinetics of methotrexate. Clin Pharmacol Ther (1973) 1.55
Propranolol and amitriptyline in prophylaxis of migraine. Pharmacokinetic and therapeutic effects. Arch Neurol (1993) 1.50
Status of drug approval processes and regulation of medications for children. Curr Opin Pediatr (1995) 1.50
Randomized, prospective double-blind trial of metoclopramide and placebo for gastroesophageal reflux in infants. J Pediatr (1989) 1.47
Comparative effects of lovastatin and niacin in primary hypercholesterolemia. A prospective trial. Arch Intern Med (1994) 1.46
Observer variability in the diagnosis and management of the hysterosalpingogram. Fertil Steril (1997) 1.45
Adverse drug reactions in children leading to hospital admission. Pediatrics (1988) 1.42
The meetabolism of amiloride hydroloride in man. Clin Pharmacol Ther (1969) 1.33
Treatment of Pancreatic Cysts. Ann Surg (1948) 1.32
The effect of spironolactone on antipyrine metabolism in man. Pharmacology (1973) 1.31
Computer-controlled infusion of intravenous dexmedetomidine hydrochloride in adult human volunteers. Anesthesiology (1993) 1.30
Correlation of the plasma elimination of antipyrine and the appearance of 4-hydroxy antipyrine in the urine of man. Biochem Pharmacol (1974) 1.28
Secondary biosynthetic defects in women with late-onset congenital adrenal hyperplasia. N Engl J Med (1990) 1.28
Absorption of orally given digoxin preparations. JAMA (1972) 1.27
The effects of urine pH and plasma protein binding on the renal clearance of disopyramide. Clin Pharmacokinet (1977) 1.25
Effect of route of administration and effusions on methotrexate pharmacokinetics. Cancer Res (1974) 1.22
Nafenopin-induced hepatic microbody (peroxisome) proliferation and catalase synthesis in rats and mice. Absence of sex difference in response. J Cell Biol (1974) 1.21
Evaluation of the efficacy, safety, and tolerability of ezetimibe in primary hypercholesterolaemia: a pooled analysis from two controlled phase III clinical studies. Int J Clin Pract (2003) 1.19
Di-(2-ethylhexyl)phthalate: an industrial plasticizer induces hypolipidemia and enhances hepatic catalase and carnitine acetyltransferase activities in rat and mice. Life Sci (1976) 1.14
Phenytoin: pharmacokinetics and bioavailability. Clin Pharmacol Ther (1976) 1.14
Long-term effects of clofibrate (Atromid-S) on serum lipids in man. Circulation (1969) 1.11
Mitogenic and carcinogenic effects of a hypolipidemic peroxisome proliferator, [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14, 643), in rat and mouse liver. Cancer Res (1979) 1.09
Theophylline bioavailability following chronic dosing of an elixir and two solid dosage forms. J Pharm Sci (1978) 1.09
Absorption and metabolism of L-dopa by the human stomach. Eur J Clin Invest (1971) 1.07
Drugs and drug metabolites as environmental contaminants: chlorophenoxyisobutyrate and salicyclic acid in sewage water effluent. Life Sci (1977) 1.07
Clinical complications of corticosteroid therapy. A selected review. Med Clin North Am (1973) 1.06
Expression of the genes encoding the insulin-like growth factors and their receptors in the human ovary. J Clin Endocrinol Metab (1992) 1.04
Effects of antacids on gastric emptying. Gastroenterology (1976) 1.04
Metabolic responses to acute and chronic L-dopa administration in patients with parkinsonism. N Engl J Med (1972) 1.04
Effect of in vivo elevation of free fatty acids on protein binding of drugs. Pharmacology (1974) 1.02
Maternal absorption and placental transfer of sulfasalazine. Am J Obstet Gynecol (1977) 1.02
Tumors in male rats fed ethyl chlorophenoxyisobutyrate, a hypolipidemic drug. Cancer Res (1979) 1.00
The alteration of plasma proteins in uremia as reflected in their ability to bind digitoxin and diphenylhydantoin. Pharmacology (1972) 1.00
Simultaneous measurement of chloramphenicol and chloramphenicol succinate by high-performance liquid chromatography. J Chromatogr (1980) 1.00
The effects of antacids on the absorption of orally administered pentobarbital in the rat. J Pharmacol Exp Ther (1971) 1.00
Germ cell tumors of the ovary arising after dermoid cyst resection: a long-term follow-up study. Obstet Gynecol (1994) 1.00
Relative bioavailability of intravenous chloramphenicol succinate and oral chloramphenicol palmitate in infants and children. J Pediatr (1981) 1.00
Spontaneous ovarian hyperstimulation syndrome and hyperreactio luteinalis are entities in continuum. Ultrasound Obstet Gynecol (2004) 0.99
Correlation between plasma diphenhydramine level and sedative and antihistamine effects. Clin Pharmacol Ther (1978) 0.99
Effect of cimetidine on absorption of oral tetracycline in mice. Pharmacology (1980) 0.99
Clinical pharmacokinetics of methotrexate. Clin Pharmacokinet (1978) 0.99
Prolongation of the latent period in patients with premature rupture of the membranes by avoiding digital examination. Int J Gynaecol Obstet (1990) 0.99
Pharmacokinetics of chloramphenicol and chloramphenicol succinate in infants and children. J Pediatr (1981) 0.98
Successful pregnancy following replacement of embryos previously refrozen at blastocyst stage: case report. Hum Reprod (2001) 0.96
Prescription writing by generic name and drug cost. J Chronic Dis (1967) 0.96
Hepatic effects of some [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio] acetic acid (WY-14,643) analogs in the mouse. Arch Int Pharmacodyn Ther (1977) 0.95
Impaired bowel motility following small intestinal transplantation. J Surg Res (1989) 0.95
The relaxing effect of aluminum and lanthanum on rat and human gastric smooth muscle in vitro. Eur J Pharmacol (1973) 0.95
L-dopa treatment failure: explanation and correction. Br Med J (1970) 0.95
Measuring gastric volume by dye dilution. Gut (1981) 0.95
Drug interactions with warfarin. Arch Intern Med (1968) 0.95
A comparative study of drug metabolism in the isolated perfused liver and in vivo in rats. Eur J Pharmacol (1970) 0.95
Effect of portacaval shunt on the disposition of drugs with and without first-pass effect. J Pharmacol Exp Ther (1975) 0.94
Characterization of intraperitoneal cytokines and nitrites in women with severe ovarian hyperstimulation syndrome. Fertil Steril (1996) 0.94
Diffusion of moxalactam into the cerebrospinal fluid in children with bacterial meningitis. J Pediatr (1981) 0.94
Investigation of terbinafine as a CYP2D6 inhibitor in vivo. Clin Pharmacol Ther (1999) 0.93
Transfer of frozen-thawed embryos in artificially prepared cycles with and without prior gonadotrophin-releasing hormone agonist suppression: a prospective randomized study. Hum Reprod (1998) 0.93
Microbodies in experimentally altered cells. VI. Thyroxine displacement from plasma proteins and clofibrate effect. Arch Int Pharmacodyn Ther (1969) 0.93
Drug interactions. Pharmacol Physicians (1970) 0.93
A role for CTLA-4-mediated inhibitory signals in peripheral T cell tolerance? Novartis Found Symp (1998) 0.93
Human follicular nitric oxide pathway: relationship to follicular size, oestradiol concentrations and ovarian blood flow. Hum Reprod (1996) 0.93
Drug protein binding and the nephrotic syndrome. Clin Pharmacokinet (1976) 0.92
Pharmacokinetics of drugs in patients with the nephrotic syndrome. J Clin Invest (1975) 0.92
Pharmacokinetics of 1-beta-D-arabinofuranosylcytosine in humans. Cancer Res (1974) 0.92
Expanded Clinical Evaluation of Lovastatin (EXCEL) study results: two-year efficacy and safety follow-up. Am J Cardiol (1994) 0.92
Migraine prophylaxis. A comparison of propranolol and amitriptyline. Arch Neurol (1987) 0.91
Omeprazole and the induction of human cytochrome P-450: a response to concerns about potential adverse effects. Gastroenterology (1991) 0.91
Insulin-like growth factor I as an intraovarian regulator: basic and clinical implications. Ann N Y Acad Sci (1991) 0.91
Expression of gelatinase B by trophoblast cells: down-regulation by progesterone. Am J Obstet Gynecol (1998) 0.90
Reversed-phase high-performance liquid chromatographic method to determine ceftriaxone in biological fluids. J Chromatogr (1984) 0.89
Long-term blood cholesterol-lowering effects of a dietary fiber supplement. Am J Prev Med (1999) 0.89
Expanded clinical evaluation of lovastatin (EXCEL) study results: III. Efficacy in modifying lipoproteins and implications for managing patients with moderate hypercholesterolemia. Am J Med (1991) 0.88
Ion pair extraction of pharmaceutical amines. Role of dipolar solvating agents in extraction of dextromethorphan. Anal Chem (1967) 0.88
Effects of fenofibrate on plasma lipoproteins in hypercholesterolemia and combined hyperlipidemia. Am J Med (1987) 0.88
Induction of salicyluric acid formation in rheumatoid arthritis patients treated with salicylates. Clin Pharmacokinet (1983) 0.87
The effect of butoxamine on catecholamine-induced metabolic changes in humans. Clin Pharmacol Ther (1966) 0.87