Published in Tissue Antigens on January 01, 1974
Immunological studies in cystic fibrosis. Arch Dis Child (1978) 1.20
HLA in eczema and hay fever. Clin Exp Immunol (1977) 1.15
HL--A typing in Northern Ireland 1971-74. Ulster Med J (1975) 0.86
Congenital Obliteration of Bile Ducts and Icterus Gravis Neonatorum. Br Med J (1945) 6.41
Susceptibility to ankylosing spondylitis in twins: the role of genes, HLA, and the environment. Arthritis Rheum (1997) 4.14
N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen. Proc Natl Acad Sci U S A (1984) 3.09
Isoniazid liver injury: clinical spectrum, pathology, and probable pathogenesis. Ann Intern Med (1976) 2.33
National organ matching and distribution service. Br Med J (1974) 2.22
Treatment-induced pathologic necrosis: a predictor of local recurrence and survival in patients receiving neoadjuvant therapy for high-grade extremity soft tissue sarcomas. J Clin Oncol (2001) 2.20
Epidemic of liver disease caused by hydrochlorofluorocarbons used as ozone-sparing substitutes of chlorofluorocarbons. Lancet (1997) 2.09
"Molecular crossmatching" for allogeneic bone marrow transplants by DNA single-strand polymorphism analysis. Lancet (1993) 2.04
HLA class I associations of ankylosing spondylitis in the white population in the United Kingdom. Ann Rheum Dis (1996) 1.79
Subcellular binding and effects on calcium homeostasis produced by acetaminophen and a nonhepatotoxic regioisomer, 3'-hydroxyacetanilide, in mouse liver. J Biol Chem (1989) 1.75
Oxidation of alpha-methyldopa and other catechols by cytochrome P-450-generated superoxide anion: possible mechanism of methyldopa hepatitis. Mol Pharmacol (1976) 1.73
Unravelling an HLA-DR association in childhood acute lymphoblastic leukemia. Blood (1999) 1.68
Prediction of outcome in Graves' disease after carbimazole treatment. Q J Med (1986) 1.68
Should anti-D immunoglobulin be given antenatally? Lancet (1980) 1.60
Pennyroyal toxicity: measurement of toxic metabolite levels in two cases and review of the literature. Ann Intern Med (1996) 1.55
HFE mutations, iron deficiency and overload in 10,500 blood donors. Br J Haematol (2001) 1.52
Celtic ancestry, HLA phenotype and increased risk of skin cancer. Br J Dermatol (1998) 1.47
Surgical resection and intraperitoneal chemotherapy for recurrent abdominal sarcomas. Ann Surg Oncol (1999) 1.46
HLA-A and B antigen frequencies in Welsh coalworkers with pneumoconiosis and Caplan's syndrome. Tissue Antigens (1979) 1.40
Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4. Biochem Pharmacol (1993) 1.38
Isoniazid and iproniazid: activation of metabolites to toxic intermediates in man and rat. Science (1976) 1.38
Primary immunolocalization of estrogen and progesterone target cells in the human anterior cruciate ligament. J Orthop Res (1996) 1.37
Parasympathetic withdrawal is an integral component of autonomic imbalance in congestive heart failure: demonstration in human subjects and verification in a paced canine model of ventricular failure. J Am Coll Cardiol (1991) 1.35
Influence of the HLA-DRB1 locus on susceptibility and severity in rheumatoid arthritis. QJM (1996) 1.31
Primary musculoskeletal neoplasms: effectiveness of core-needle biopsy. Radiology (1999) 1.27
Alleles at D6S265 and D6S105 define a haemochromatosis-specific genotype. Br J Haematol (1994) 1.23
Advantages of low dose steroid from the day after renal transplantation. Transplantation (1980) 1.22
Acetaminophen-induced oxidation of protein thiols. Contribution of impaired thiol-metabolizing enzymes and the breakdown of adenine nucleotides. J Biol Chem (1990) 1.19
Molecular basis for several drug-induced nephropathies. Am J Med (1977) 1.18
The spontaneous and enzymatic reaction of N-acetyl-p-benzoquinonimine with glutathione: a stopped-flow kinetic study. Arch Biochem Biophys (1988) 1.17
Analysis of the distribution of HLA-B alleles in populations from five continents. Hum Immunol (2001) 1.15
The effect of HLA-DR genes on susceptibility to and severity of ankylosing spondylitis. Arthritis Rheum (1998) 1.14
Prenatal care and the low birth weight infant. Obstet Gynecol (1985) 1.13
Application of alternative fumigants through drip irrigation systems. Phytopathology (2002) 1.11
The second example of anti-Doa. Vox Sang (1967) 1.11
HLA and multiple sclerosis in south east Wales. J Neurol Neurosurg Psychiatry (1987) 1.11
Human cytochrome P450 2E1 is a major autoantigen associated with halothane hepatitis. Chem Res Toxicol (1997) 1.10
The complex interaction between ethanol and acetaminophen. Clin Pharmacol Ther (1996) 1.08
Synthesis, decomposition kinetics, and preliminary toxicological studies of pure N-acetyl-p-benzoquinone imine, a proposed toxic metabolite of acetaminophen. J Med Chem (1982) 1.07
Serum ferritin, blood donation, iron stores and haemochromatosis. Transfus Med (1993) 1.07
Non-B27 MHC associations of ankylosing spondylitis. Genes Immun (2006) 1.06
Enhanced acetaminophen hepatotoxicity in transgenic mice overexpressing BCL-2. Mol Pharmacol (2001) 1.05
Oxidation of acetaminophen to its toxic quinone imine and nontoxic catechol metabolites by baculovirus-expressed and purified human cytochromes P450 2E1 and 2A6. Chem Res Toxicol (1998) 1.05
Dose-dependent pharmacokinetics of acetaminophen: evidence of glutathione depletion in humans. Clin Pharmacol Ther (1987) 1.03
Fine mapping of the MHC Class III region demonstrates association of AIF1 and rheumatoid arthritis. Rheumatology (Oxford) (2008) 1.02
Isoniazid hepatoxicity: the relationship between covalent binding and metabolism in vivo. J Pharmacol Exp Ther (1980) 1.01
Cytochrome P-450 and NADPH cytochrome c reductase in rat brain: formation of catechols and reactive catechol metabolites. Biochem Biophys Res Commun (1977) 1.00
Ethanol and production of the hepatotoxic metabolite of acetaminophen in healthy adults. Clin Pharmacol Ther (2000) 0.99
Cytochrome P-450-mediated oxidation of 2-hydroxyestrogens to reactive intermediates. Biochem Biophys Res Commun (1976) 0.99
Minimally invasive breast carcinoma staging using lymphatic mapping with radiolabeled dextran. Cancer (1998) 0.98
Mechanisms of N-acetyl-p-benzoquinone imine cytotoxicity. Mol Pharmacol (1985) 0.97
A comparative study of mouse liver proteins arylated by reactive metabolites of acetaminophen and its nonhepatotoxic regioisomer, 3'-hydroxyacetanilide. Chem Res Toxicol (1995) 0.97
Involvement of human cytochrome P450 2D6 in the bioactivation of acetaminophen. Drug Metab Dispos (2000) 0.97
Postpartum thyroiditis and long-term thyroid status: prognostic influence of thyroid peroxidase antibodies and ultrasound echogenicity. J Clin Endocrinol Metab (2000) 0.96
Metabolic activation of 2,4-diaminoanisole, a hair-dye component--III. Role of cytochrome P-450 metabolism in irreversible binding in vivo. Biochem Pharmacol (1979) 0.95
Hereditary haemochromatosis and blood donation. BMJ (1991) 0.95
The microsomal metabolism and site of covalent binding to protein of 3'-hydroxyacetanilide, a nonhepatotoxic positional isomer of acetaminophen. Drug Metab Dispos (1985) 0.94
In vitro effects of acetaminophen metabolites and analogs on the respiration of mouse liver mitochondria. Arch Biochem Biophys (1989) 0.94
Role of CYP1A2 in the hepatotoxicity of acetaminophen: investigations using Cyp1a2 null mice. Toxicol Appl Pharmacol (1998) 0.94
The formation of arylating and alkylating metabolites of phenacetin in hamsters and hamster liver microsomes. Mol Pharmacol (1981) 0.94
Soft tissue echinococcosis: a report of two cases and review of the literature. Clin Orthop Relat Res (2001) 0.94
Comparative genotoxicity and nephrotoxicity studies of the two halogenated flame retardants tris(1,3-dichloro-2-propyl)phosphate and tris(2,3-dibromopropyl)phosphate. Acta Pharmacol Toxicol (Copenh) (1985) 0.93
Accentuated antagonism between beta-adrenergic and vagal effects on ventricular refractoriness in humans. Circulation (1988) 0.93
The covalent binding of acetaminophen to protein. Evidence for cysteine residues as major sites of arylation in vitro. Chem Biol Interact (1984) 0.93
Lack of evidence for N-hydroxyacetaminophen as a reactive metabolite of acetaminophen in vitro. Biochem Pharmacol (1980) 0.92
Reduction and glutathione conjugation reactions of N-acetyl-p-benzoquinone imine and two dimethylated analogues. Mol Pharmacol (1984) 0.92
Orientation of caffeine within the active site of human cytochrome P450 1A2 based on NMR longitudinal (T1) relaxation measurements. Arch Biochem Biophys (2000) 0.92
Hepatic protein arylation, glutathione depletion, and metabolite profiles of acetaminophen and a non-hepatotoxic regioisomer, 3'-hydroxyacetanilide, in the mouse. Drug Metab Dispos (1991) 0.92
HLA-A and B antigen frequencies in an asbestos exposed population with normal and abnormal chest radiographs. Tissue Antigens (1979) 0.92
Antibody protein levels in the maternal serum in rhesus iso-immunization. J Obstet Gynaecol Br Commonw (1972) 0.92
The HLA-B7Qui antigen is encoded by a new subtype of HLA-B27 (B*2708). Tissue Antigens (1994) 0.91
Peroxidase-mediated formation of reactive metabolites of acetaminophen. Mol Pharmacol (1981) 0.91
Protein and nonprotein cysteinyl thiol modification by N-acetyl-p-benzoquinone imine via a novel ipso adduct. Biochemistry (1999) 0.91
Efficacy and uptake of soil-applied imidacloprid in the control of Asian citrus psyllid and a citrus leafminer, two foliar-feeding citrus pests. J Econ Entomol (2010) 0.91
Comparative cytotoxic effects of acetaminophen (N-acetyl-p-aminophenol), a non-hepatotoxic regioisomer acetyl-m-aminophenol and their postulated reactive hydroquinone and quinone metabolites in monolayer cultures of mouse hepatocytes. Biochem Pharmacol (1991) 0.90
A long-term follow-up of postpartum thyroiditis. Clin Endocrinol (Oxf) (1990) 0.90
Baculovirus expression and purification of human and rat cytochrome P450 2E1. Arch Biochem Biophys (1996) 0.89
Cytotoxic effects of N-acetyl-p-benzoquinone imine, a common arylating intermediate of paracetamol and N-hydroxyparacetamol. Biochem Pharmacol (1984) 0.89
Hepatotoxicity of germander (Teucrium chamaedrys L.) and one of its constituent neoclerodane diterpenes teucrin A in the mouse. Chem Res Toxicol (1995) 0.89
Identification and catheter ablation of a zone of slow conduction in the reentrant circuit of ventricular tachycardia in humans. J Am Coll Cardiol (1988) 0.89
Primary standardization for the ELISA of serum thyroperoxidase and thyroglobulin antibodies and their prevalence in a normal Welsh population. J Clin Lab Immunol (1990) 0.89
Metabolic activation and drug toxicity. J Med Chem (1982) 0.89
Inhibition and induction of cytochrome P4502E1-catalyzed oxidation by isoniazid in humans. Clin Pharmacol Ther (1993) 0.88
N-acetyl-p-benzoquinone imine-induced changes in the energy metabolism in hepatocytes. Chem Biol Interact (1990) 0.88
Cytochrome P-450 isozyme selectivity in the oxidation of acetaminophen. Chem Res Toxicol (1992) 0.87
Linkage study on the 'ridges-off-the-end' and Nelson syndromes. Hum Hered (1973) 0.87
An evaluation of the ethidium bromide microcytotoxicity test. J Immunol Methods (1974) 0.87
Hepatotoxicity and pulmonary toxicity of pennyroyal oil and its constituent terpenes in the mouse. Toxicol Appl Pharmacol (1982) 0.87
Warfarin-stereochemical aspects of its metabolism by rat liver microsomes. Biochem Pharmacol (1976) 0.87
Improved clinical efficacy of external cardioversion by fluoroscopic electrode positioning and comparison to internal cardioversion in patients with atrial fibrillation. Pacing Clin Electrophysiol (1999) 0.86
The formation and toxicity of catechol metabolites of acetaminophen in mice. Drug Metab Dispos (1984) 0.86
Quantitative determination of the glutathione, cysteine, and N-acetyl cysteine conjugates of acetaminophen by high-pressure liquid chromatography. Anal Biochem (1977) 0.86
Stereoselectivity of naphthalene epoxidation by mouse, rat, and hamster pulmonary, hepatic, and renal microsomal enzymes. Drug Metab Dispos (1987) 0.86
Human aromatase in high yield and purity by perfusion chromatography and its characterization by difference spectroscopy and mass spectrometry. Protein Expr Purif (2001) 0.86
Primary osteosarcoma of a metatarsal bone. Skeletal Radiol (2000) 0.86
Jejunal villous changes associated with farmer's lung. Postgrad Med J (1981) 0.86
Studies on the microsomal formation of arylating metabolites of acetaminophen and phenacetin. Mol Pharmacol (1977) 0.86
Intermittent corticotrophin therapy. Study of lymphocyte transformation in vitro in rheumatoid arthritis. Ann Rheum Dis (1969) 0.86
HL--A typing in Northern Ireland 1971-74. Ulster Med J (1975) 0.86