B Magasanik

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Covalent modification of the glnG product, NRI, by the glnL product, NRII, regulates the transcription of the glnALG operon in Escherichia coli. Proc Natl Acad Sci U S A 1986 10.43
2 Control site location and transcriptional regulation in Escherichia coli. Microbiol Rev 1991 8.11
3 Resistance to catabolite repression of histidase and proline oxidase during nitrogen-limited growth of Klebsiella aerogenes. J Biol Chem 1971 8.08
4 Genetic control of nitrogen assimilation in bacteria. Annu Rev Genet 1982 7.77
5 Transcription of glnA by purified Escherichia coli components: core RNA polymerase and the products of glnF, glnG, and glnL. Proc Natl Acad Sci U S A 1985 7.49
6 Glutamine synthetase and the regulation of histidase formation in Klebsiella aerogenes. J Biol Chem 1973 7.30
7 Biochemical parameters of glutamine synthetase from Klebsiella aerogenes. J Bacteriol 1977 6.99
8 Effect of infection with T-even phage on the inducible synthesis of beta-glactosidase in Escherichia coli. J Mol Biol 1967 6.36
9 Genetic control of glutamine synthetase in Klebiella aerogenes. J Bacteriol 1975 5.87
10 Catabolite-insensitive revertants of lac promoter mutants. Proc Natl Acad Sci U S A 1970 5.83
11 Transcription of glnA in E. coli is stimulated by activator bound to sites far from the promoter. Cell 1986 5.81
12 Regulation of the synthesis of enzymes responsible for glutamate formation in Klebsiella aerogenes. J Biol Chem 1973 5.81
13 Genetic and metabolic control of enzymes responsible for histidine degradation in Salmonella typhimurium. 4-imidazolone-5-propionate amidohydrolase and N-formimino-L-glutamate formiminohydrolase. J Biol Chem 1971 5.79
14 Physical and genetic characterization of the glnA--glnG region of the Escherichia coli chromosome. Proc Natl Acad Sci U S A 1981 5.63
15 Activation of transcription of hut DNA by glutamine synthetase. Proc Natl Acad Sci U S A 1974 5.61
16 Expression of glnA in Escherichia coli is regulated at tandem promoters. Proc Natl Acad Sci U S A 1985 4.77
17 Catabolite sensitive site of the lac operon. Nature 1969 4.29
18 Complex glnA-glnL-glnG operon of Escherichia coli. J Bacteriol 1982 4.25
19 Characterization of a gene, glnL, the product of which is involved in the regulation of nitrogen utilization in Escherichia coli. J Bacteriol 1982 4.19
20 Role of glnB and glnD gene products in regulation of the glnALG operon of Escherichia coli. J Bacteriol 1985 4.19
21 Crosstalk between bacterial chemotaxis signal transduction proteins and regulators of transcription of the Ntr regulon: evidence that nitrogen assimilation and chemotaxis are controlled by a common phosphotransfer mechanism. Proc Natl Acad Sci U S A 1988 3.94
22 Initiation of transcription at the bacterial glnAp2 promoter by purified E. coli components is facilitated by enhancers. Cell 1987 3.85
23 Phosphorylation of nitrogen regulator I (NRI) of Escherichia coli. Proc Natl Acad Sci U S A 1988 3.83
24 Isolation of the nitrogen assimilation regulator NR(I), the product of the glnG gene of Escherichia coli. Proc Natl Acad Sci U S A 1983 3.80
25 Identification of the structural gene for glutamine synthetase in Klebsiella aerogenes. J Bacteriol 1975 3.76
26 Glutamine synthetase as a regulator of enzyme synthesis. Curr Top Cell Regul 1974 3.69
27 Involvement of the product of the glnF gene in the autogenous regulation of glutamine synthetase formation in Klebsiella aerogenes. J Bacteriol 1978 3.58
28 Regulation of synthesis of glutamine synthetase by adenylylated glutamine synthetase. Proc Natl Acad Sci U S A 1975 3.56
29 The URE2 gene product of Saccharomyces cerevisiae plays an important role in the cellular response to the nitrogen source and has homology to glutathione s-transferases. Mol Cell Biol 1991 3.52
30 Induction and repression of the histidine-degrading enzymes of Bacillus subtilis. J Biol Chem 1968 3.36
31 Regulatory mutations in the Klebsiella aerogenes structural gene for glutamine synthetase. J Bacteriol 1977 3.27
32 Sequence and expression of GLN3, a positive nitrogen regulatory gene of Saccharomyces cerevisiae encoding a protein with a putative zinc finger DNA-binding domain. Mol Cell Biol 1991 3.22
33 Regulation of expression from the glnA promoter of Escherichia coli in the absence of glutamine synthetase. Proc Natl Acad Sci U S A 1980 3.19
34 Identification and regulation of the glnL operator-promoter of the complex glnALG operon of Escherichia coli. J Bacteriol 1984 3.18
35 Genetic control of histidine degradation in Salmonella typhimurium, strain LT-2. J Biol Chem 1969 3.03
36 Genetic and metabolic control of histidase and urocanase in Salmonella typhimurium, strain 15-59. J Biol Chem 1969 2.92
37 Regulation of glutamine-repressible gene products by the GLN3 function in Saccharomyces cerevisiae. Mol Cell Biol 1984 2.90
38 Genetics and physiology of proline utilization in Saccharomyces cerevisiae: enzyme induction by proline. J Bacteriol 1979 2.84
39 Transient repression of the lac operon. J Bacteriol 1967 2.79
40 The induction of urea carboxylase and allophanate hydrolase in Saccharomyces cerevisiae. J Biol Chem 1973 2.68
41 Induction and repression of the histidine-degrading enzymes in Aerobacter aerogenes. J Biol Chem 1965 2.64
42 Urease of Klebsiella aerogenes: control of its synthesis by glutamine synthetase. J Bacteriol 1977 2.61
43 Nature and self-regulated synthesis of the repressor of the hut operons in Salmonella typhimurium. Proc Natl Acad Sci U S A 1971 2.58
44 The induction of arginase in Saccharomyces cerevisiae. J Biol Chem 1973 2.53
45 Regulation at the glnL-operator-promoter of the complex glnALG operon of Escherichia coli. J Bacteriol 1983 2.52
46 Regulation of nitrogen assimilation in Saccharomyces cerevisiae: roles of the URE2 and GLN3 genes. J Bacteriol 1988 2.51
47 Exogenous and endogenous induction of the histidine-degrading enzymes in Aerobacter aerogenes. J Biol Chem 1965 2.49
48 Regulation of enzyme formation in Klebsiella aerogenes by episomal glutamine synthetase of Escherichia coli. J Bacteriol 1976 2.46
49 Role of integration host factor in the regulation of the glnHp2 promoter of Escherichia coli. Proc Natl Acad Sci U S A 1991 2.42
50 Role of the GATA factors Gln3p and Nil1p of Saccharomyces cerevisiae in the expression of nitrogen-regulated genes. Proc Natl Acad Sci U S A 1995 2.35
51 Genetic control of catabolite repression of the lac operon in Escherichia coli. Biochem Biophys Res Commun 1965 2.30
52 Gene order of the histidine utilization (hut) operons in Klebsiella aerogenes. J Bacteriol 1975 2.25
53 Transcriptional and posttranslational regulation of the general amino acid permease of Saccharomyces cerevisiae. J Bacteriol 1995 2.21
54 Glucose-lactose diauxie in Escherichia coli. J Bacteriol 1967 2.14
55 Inhibition of lacZ gene translation initiation in trp-lac fusion strains. J Bacteriol 1974 2.14
56 The two operons of the histidine utilization system in Salmonella typhimurium. J Biol Chem 1971 2.12
57 Autogenous regulation of the synthesis of glutamine synthetase in Klebsiella aerogenes. J Bacteriol 1977 2.12
58 Glutamine synthetase of Klebsiella aerogenes: genetic and physiological properties of mutants in the adenylylation system. J Bacteriol 1977 2.11
59 Nitrogen regulation system of Klebsiella aerogenes: the nac gene. J Bacteriol 1983 2.09
60 Regulation of histidase synthesis in intergeneric hybrids of enteric bacteria. J Bacteriol 1976 2.09
61 Reversible phosphorylation of an enhancer binding protein regulates the transcription of bacterial nitrogen utilization genes. Trends Biochem Sci 1988 2.02
62 Physiological basis of transient repression of catabolic enzymes in Escherichia coli. J Bacteriol 1970 2.00
63 Regulation of the synthesis of glutamine synthetase by the PII protein in Klebsiella aerogenes. Proc Natl Acad Sci U S A 1980 1.97
64 Genetics and physiology of proline utilization in Saccharomyces cerevisiae: mutation causing constitutive enzyme expression. J Bacteriol 1979 1.96
65 Mutants of Klebsiella aerogenes lacking glutamate dehydrogenase. J Bacteriol 1974 1.95
66 Purification and properties of glutamine synthetase from Saccharomyces cerevisiae. J Biol Chem 1983 1.95
67 Klebsiella aerogenes strain carrying drug-resistance determinants and a lac plasmid. J Bacteriol 1972 1.94
68 The product of glnL is not essential for regulation of bacterial nitrogen assimilation. J Bacteriol 1983 1.89
69 Role of NAD-linked glutamate dehydrogenase in nitrogen metabolism in Saccharomyces cerevisiae. J Bacteriol 1990 1.87
70 Role of the complex upstream region of the GDH2 gene in nitrogen regulation of the NAD-linked glutamate dehydrogenase in Saccharomyces cerevisiae. Mol Cell Biol 1991 1.85
71 Glutamate dehydrogenase: genetic mapping and isolation of regulatory mutants of Klebsiella aerogenes. J Bacteriol 1976 1.85
72 Glutamine synthetase of Klebsiella aerogenes: properties of glnD mutants lacking uridylyltransferase. J Bacteriol 1978 1.83
73 Three regulatory systems control production of glutamine synthetase in Saccharomyces cerevisiae. Mol Cell Biol 1984 1.78
74 Catabolite repression gene of Escherichia coli. J Bacteriol 1969 1.78
75 Sequence of the GLN1 gene of Saccharomyces cerevisiae: role of the upstream region in regulation of glutamine synthetase expression. J Bacteriol 1992 1.77
76 Ammonia regulation of amino acid permeases in Saccharomyces cerevisiae. Mol Cell Biol 1983 1.75
77 Interaction of the GATA factor Gln3p with the nitrogen regulator Ure2p in Saccharomyces cerevisiae. J Bacteriol 1996 1.75
78 L-Asparaginase of Klebsiella aerogenes. Activation of its synthesis by glutamine synthetase. J Biol Chem 1976 1.73
79 Phosphorylation of nitrogen regulator I of Escherichia coli induces strong cooperative binding to DNA essential for activation of transcription. Proc Natl Acad Sci U S A 1992 1.72
80 Nature of the effector of catabolite repression of beta-galactosidase in Escherichia coli. J Bacteriol 1966 1.72
81 Activation of glnA transcription by nitrogen regulator I (NRI)-phosphate in Escherichia coli: evidence for a long-range physical interaction between NRI-phosphate and RNA polymerase. J Bacteriol 1989 1.71
82 Mechanism of tryptophanase induction in Escherichia coli. J Mol Biol 1967 1.71
83 Recognition of nitrogen-responsive upstream activation sequences of Saccharomyces cerevisiae by the product of the GLN3 gene. J Bacteriol 1995 1.70
84 Reaction of lac-specific ribonucleic acid from Escherichia coli with lac deoxyribonucleic acid. J Biol Chem 1974 1.67
85 Purification of nitrogen regulator II, the product of the glnL (ntrB) gene of Escherichia coli. J Bacteriol 1986 1.67
86 Genetic basis of histidine degradation in Bacillus subtilis. J Biol Chem 1970 1.60
87 Urocanase and N-formimino-L-glutamate formiminohydrolase of Bacillus subtilis, two enzymes of the histidine degradation pathway. J Biol Chem 1970 1.58
88 Positive and negative effects of DNA bending on activation of transcription from a distant site. J Mol Biol 1992 1.55
89 Molecular basis of transient repression of beta-galactosidase in Escherichia coli. J Bacteriol 1969 1.54
90 Classical and postclassical modes of regulation of the synthesis of degradative bacterial enzymes. Prog Nucleic Acid Res Mol Biol 1976 1.54
91 Mechanism of beta-galactosidase induction in Escherichia coli. J Mol Biol 1967 1.52
92 Role of glnA-linked genes in regulation of glutamine synthetase and histidase formation in Klebsiella aerogenes. J Bacteriol 1982 1.50
93 Mutations that create new promoters suppress the sigma 54 dependence of glnA transcription in Escherichia coli. J Bacteriol 1987 1.44
94 The catabolite repression gene of the lac operon in Escherichia coli. J Mol Biol 1967 1.41
95 The pathway of myo-inositol degradation in Aerobacter aerogenes. Dehydrogenation and dehydration. J Biol Chem 1966 1.40
96 Proline: an essential intermediate in arginine degradation in Saccharomyces cerevisiae. J Bacteriol 1980 1.40
97 Biochemical and physiological aspects of glutamine synthetase inactivation in Saccharomyces cerevisiae. J Biol Chem 1984 1.39
98 2-Ketoglutarate and the regulation of aconitase and histidase formation in Bacillus subtilis. J Bacteriol 1984 1.37
99 Three regulatory systems control expression of glutamine synthetase in Saccharomyces cerevisiae at the level of transcription. Mol Gen Genet 1989 1.34
100 Subcellular compartmentation in control of converging pathways for proline and arginine metabolism in Saccharomyces cerevisiae. J Bacteriol 1981 1.33
101 The pathway of myo-inositol degradation in Aerobacter aerogenes. Conversion of 2-deoxy-5-keto-D-gluconic acid to glycolytic intermediates. J Biol Chem 1971 1.32
102 Utilization of arginine by Klebsiella aerogenes. J Bacteriol 1978 1.32
103 Effects of glnL and other regulatory loci on regulation of transcription of glnA-lacZ fusions in Klebsiella aerogenes. J Bacteriol 1982 1.31
104 Isolation of super-repressor mutants in the histidine utilization system of Salmonella typhimurium. J Bacteriol 1975 1.26
105 Asparagine synthetases of Klebsiella aerogenes: properties and regulation of synthesis. J Bacteriol 1982 1.25
106 Expression of the hut operons of Salmonella typhimurium in Klebsiella aerogenes and in Escherichia coli. J Bacteriol 1975 1.25
107 Two transcription factors, Gln3p and Nil1p, use the same GATAAG sites to activate the expression of GAP1 of Saccharomyces cerevisiae. J Bacteriol 1996 1.24
108 Mutations in the glnG gene of Escherichia coli that result in increased activity of nitrogen regulator I. J Bacteriol 1989 1.23
109 Isolation of Bacillus subtilis mutants pleiotropically insensitive to glucose catabolite repression. J Bacteriol 1984 1.22
110 Tryptophan metabolism in Klebsiella aerogenes: regulation of the utilization of aromatic amino acids as sources of nitrogen. J Bacteriol 1981 1.22
111 Activation of transcription at sigma 54-dependent promoters on linear templates requires intrinsic or induced bending of the DNA. J Mol Biol 1996 1.20
112 The mode of action of levallorphan as an inhibitor of cell growth. Mol Pharmacol 1967 1.20
113 The pathway of myo-inositol degradation in Aerobacter aerogenes. Ring scission. J Biol Chem 1966 1.19
114 Isolation of the self-regulated repressor protein of the Hut operons of Salmonella typhimurium. Proc Natl Acad Sci U S A 1973 1.18
115 Imidazolepropionate, a nonmetabolizable inducer for the histidine-degrading enzymes in Aerobacter aerogenes. J Biol Chem 1965 1.17
116 A study in evolution: the histidine utilization genes of enteric bacteria. J Mol Biol 1979 1.15
117 Physiological and genetic analysis of the carbon regulation of the NAD-dependent glutamate dehydrogenase of Saccharomyces cerevisiae. Mol Cell Biol 1991 1.13
118 Role of GATA factor Nil2p in nitrogen regulation of gene expression in Saccharomyces cerevisiae. J Bacteriol 1997 1.12
119 Role of the promoter in activation of transcription by nitrogen regulator I phosphate in Escherichia coli. J Bacteriol 1990 1.12
120 Transcription of the lac operon of Escherichia coli. J Biol Chem 1974 1.11
121 Synthesis of oxaloacetate in Bacillus subtilis mutants lacking the 2-ketoglutarate dehydrogenase enzymatic complex. J Bacteriol 1984 1.11
122 The glnB region of the Escherichia coli chromosome. J Bacteriol 1993 1.11
123 N-formimino-L-glutamate formiminohydrolase of Aerobacter aerogenes. J Biol Chem 1965 1.07
124 DNA bending and the initiation of transcription at sigma54-dependent bacterial promoters. Proc Natl Acad Sci U S A 1997 1.06
125 A sequence-induced superhelical DNA segment serves as transcriptional enhancer. J Mol Biol 1995 1.06
126 Activation of the dephosphorylation of nitrogen regulator I-phosphate of Escherichia coli. J Bacteriol 1995 1.05
127 Regulation of glutamine synthetase by regulatory protein PII in Klebsiella aerogenes mutants lacking adenylyltransferase. J Bacteriol 1981 1.05
128 Purification and properties of aromatic amino acid aminotransferase from Klebsiella aerogenes. J Bacteriol 1981 1.03
129 Isolation of Klebsiella aerogenes mutants cis-dominant for glutamine synthetase expression. J Bacteriol 1980 1.01
130 The pathway of myo-inositol degradation in Aerobacter aerogenes. Identification of the intermediate 2-deoxy-5-keto-D-gluconic acid. J Biol Chem 1971 1.01
131 Catabolic N2-acetylornithine 5-aminotransferase of Klebsiella aerogenes: control of synthesis by induction, catabolite repression, and activation by glutamine synthetase. J Bacteriol 1978 0.98
132 Inhibition of Mitotic Poisoning by meso-Inositol. Science 1948 0.96
133 Phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase activity in the adenine-histidine auxotroph AD-3 of S. cerevisiae. Biochem Biophys Res Commun 1967 0.93
134 Deoxyribonucleic acid-binding studies on the hut repressor and mutant forms of the hut repressor of Salmonella typhimurium. J Bacteriol 1976 0.92
135 Enzymes of agmatine degradation and the control of their synthesis in Klebsiella aerogenes. J Bacteriol 1979 0.91
136 Regulation of the hut operons of Salmonella typhimurium and Klebsiella aerogenes by the heterologous hut repressors. J Bacteriol 1975 0.91
137 Gene expression after transformation of Bacillus subtilis. J Bacteriol 1970 0.90
138 Polycistronic effects of catabolite repression on the lac operon. J Bacteriol 1972 0.88
139 Physical maps of Klebsiella aerogenes and Salmonella typhimurium hut genes. J Bacteriol 1981 0.88
140 Sequential synthesis of histidine-degrading enzymes in Bacillus subtilis. J Biol Chem 1970 0.88
141 Isolation of a trans-dominant histidase-negative mutant of Salmonella typhimurium. J Bacteriol 1974 0.86
142 Serine utilization by Klebsiella aerogenes. J Bacteriol 1981 0.83
143 Asparaginase II of Saccharomyces cerevisiae. GLN3/URE2 regulation of a periplasmic enzyme. Appl Biochem Biotechnol 1997 0.81
144 Ammonia-sensitive mutant of Klebsiella aerogenes. J Bacteriol 1976 0.81
145 The role of uridylyltransferase and PII in the regulation of the synthesis of glutamine synthetase in Escherichia coli. Curr Top Cell Regul 1985 0.81
146 Regulation of glutamine synthetase. Prog Clin Biol Res 1980 0.79
147 Control by feedback repression of the enzymes of purine biosynthesis in Aerobacter aerogenes. Biochim Biophys Acta 1971 0.78
148 PII: a remarkable regulatory protein. Trends Microbiol 2000 0.76
149 Priority claims policy and disenhancement. Nature 1987 0.76
150 Regulation of the biosynthesis and interconversion of purine nucleotides. Arthritis Rheum 1965 0.75
151 No research strike at m.I.T. Science 1969 0.75
152 Studies on the structure of ribonucleic acids. 1951. Biochim Biophys Acta 1989 0.75
153 Women, please apply. Science 1971 0.75