Published in J Physiol on August 01, 1972
Stimulus-secretion coupling: cytoplasmic calcium signals and the control of ion channels in exocrine acinar cells. J Physiol (1992) 2.31
The relationship between calcium exchange and enzyme secretion in the isolated rat pancreas. J Physiol (1973) 2.25
Pancreatic acinar cells: ionic dependence of the membrane potential and acetycholine-induced depolarization. J Physiol (1973) 2.13
Pancreatic acinar cells: acetylcholine-induced membrane depolarization, calcium efflux and amylase release. J Physiol (1973) 2.12
Pancreatic acinar cells: the role of calcium in stimulus-secretion coupling. J Physiol (1976) 2.04
Pancreatic acinar cells: ionic dependence of acetylcholine-induced membrane potential and resistance change. J Physiol (1975) 1.98
Pancreatic acinar cells: membrane potential and resistance change evoked by acetylcholine. J Physiol (1974) 1.96
Amylase secretion by the perfused cat pancreas in relation to the secretion of calcium and other electrolytes and as influenced by the external ionic environment. J Physiol (1973) 1.74
Membrane potential and resistance measurement in acinar cells from salivary glands in vitro: effect of acetylcholine. J Physiol (1974) 1.34
Pancreatic acinar cells: effect of acetylcholine, pancreozymin, gastrin and secretin on membrane potential and resistance in vivo and in vitro. J Physiol (1975) 1.32
Action of cholecystokinin and cholinergic agents on calcium transport in isolated pancreatic acinar cells. J Clin Invest (1975) 1.25
Membrane potential measurement in parotid acinar cells. J Physiol (1973) 1.22
The electrogenic sodium pump in the hyperpolarizing and secretory effects of pancreozymin in the pancreatic acinar cell. J Physiol (1975) 1.22
Pancreatic acinar cells: acetylcholine-evoked electrical uncoupling and its ionic dependency. J Physiol (1978) 1.20
Electrical coupling and uncoupling of exocrine acinar cells. J Cell Biol (1978) 1.18
Pancreatic acinar cells: localization of acetylcholine receptors and the importance of chloride and calcium for acetylcholine-evoked depolarization. J Physiol (1977) 1.18
Potassium ion influx and Na+,K+-ATPase activity are required for the hamster sperm acrosome reaction. J Cell Biol (1981) 1.10
Electrophysiology of mouse parotid acini: effects of electrical field stimulation and ionophoresis of neurotransmitters. J Physiol (1980) 1.01
Regulation of fluid secretion and intracellular messengers in isolated rat pancreatic ducts by acetylcholine. J Physiol (1993) 0.99
Effects of the calcium ionophore A23187 on pancreatic acinar cell membrane potentials and amylase release. J Physiol (1977) 0.95
Stimulus-secretion coupling in pancreatic acinar cells: inhibitory effects of calcium removal and manganese addition on pancreozymin-induced amylase release. J Physiol (1976) 0.95
Progess report. Is secretin secreted? Gut (1973) 0.94
Characterization of single potassium channels in mouse pancreatic acinar cells. J Physiol (1995) 0.85
The effects of gastrin and gastrin analogues on pancreatic acinar cell membrane potential and resistance. Br J Pharmacol (1977) 0.85
Stimulus-secretion coupling in pancreatic acinar cells: influences of external sodium and calcium on responses to cholecystokinin-pancreozymin and ionophore A23187. J Physiol (1977) 0.85
beta-Adrenoceptor stimulation of exocrine secretion from the rat pancreas. Br J Pharmacol (1978) 0.83
Mouse pancreatic acinar cells: voltage-clamp study of acetylcholine-evoked membrane current. J Physiol (1981) 0.82
Mouse pancreatic acinar cells: effects of electrical field stimulation on membrane potential and resistance. J Physiol (1980) 0.79
Proceedings: Differential projection of spindle afferents from rostral and caudal parts of the mesencephalic nucleus of the fifth nerve. J Physiol (1976) 0.78
The effect of pH on the selective permeability of the guinea-pig amnion to monovalent ions. J Physiol (1972) 0.75
Proceedings: Direction selective sub-regions in striate simple cell receptive fields. J Physiol (1974) 0.75
Spontaneous subthreshold activity at motor nerve endings. J Physiol (1952) 42.17
The mechanism of pancreatic secretion. J Physiol (1902) 15.82
Stimulus-secretion coupling: the concept and clues from chromaffin and other cells. Br J Pharmacol (1968) 7.91
Pancreozymin, a stimulant of the secretion of pancreatic enzymes in extracts of the small intestine. J Physiol (1943) 7.23
Effects of acetylcholine and other medullary secretagogues and antagonists on the membrane potential of adrenal chromaffin cells: an analysis employing techniques of tissue culture. J Physiol (1967) 3.39
Glucose-induced electrical activity in pancreatic islet cells. J Physiol (1970) 3.10
Electrical activity in pancreatic islet cells: effect of ions. J Physiol (1970) 2.61
Competition between sodium and calcium ions in transmitter release at mammalian neuromuscular junctions. J Physiol (1966) 2.19
The electrophysiology of the submaxillary gland of the cat. Acta Physiol Scand (1955) 2.12
Enzyme secretion in mouse pancreas mediated by adenosine-3'5'-cyclic phosphate and inhibited by adenosine-3'-phosphate. Proc Natl Acad Sci U S A (1968) 1.77
Membrane potential measurement in cells of the adrenal gland. J Physiol (1967) 1.64
Evidence for a Poisson distribution of miniature end-plate potentials and some implications. Nature (1965) 1.51
Origin of transmembrane potentials in non-excitable cells. J Theor Biol (1970) 1.45
Effect of methacholine on pancreatic amylase synthesis. Gastroenterology (1968) 1.09
Glucose-induced electrical activity in pancreatic islet cells. J Physiol (1970) 3.10
Electrical activity in pancreatic islet cells: effect of ions. J Physiol (1970) 2.61
Electrical activity in pancreatic islet cells. Nature (1968) 2.53
Ultrastructural morphometry of the pancreatic -cell. Diabetologia (1973) 2.23
Molecular characterisation of recombinant green fluorescent protein by fluorescence correlation microscopy. Biochem Biophys Res Commun (1995) 2.13
Pancreatic acinar cells: ionic dependence of the membrane potential and acetycholine-induced depolarization. J Physiol (1973) 2.13
Pancreatic acinar cells: acetylcholine-induced membrane depolarization, calcium efflux and amylase release. J Physiol (1973) 2.12
Electrical characteristics of pancreatic islet cells. J Physiol (1975) 1.96
Three-dimensional hydrogen-bond geometry and probability information from a crystal survey. J Comput Aided Mol Des (1996) 1.69
Membrane potential measurement in cells of the adrenal gland. J Physiol (1967) 1.64
Pancreatic islet cells: effects of monosaccharides, glycolytic intermediates and metabolic inhibitors on membrane potential and electrical activity. J Physiol (1975) 1.64
Control of pancreatic amylase release in vitro: effects of ions, cyclic AMP, and colchicine. Br J Pharmacol (1972) 1.56
The docking manoeuvre at a drug receptor: a quantum mechanical study of intercalative attack of ethidium and its carboxylated derivative on a DNA fragment. Philos Trans R Soc Lond B Biol Sci (1979) 1.34
The presynaptic effects of quaternary ammonium compounds on the acetylcholine metabolism of a sympathetic ganglion. Br J Pharmacol Chemother (1966) 1.28
The ionogenic nature of the secretory-granule membrane. Electrokinetic properties of isolated chromaffin granules. Biochem J (1972) 1.26
The effect of pancreozymin and acetylcholine on the membrane potential of the pancreatic acinar cells. Experientia (1972) 1.18
Drug-receptor recognition: electrostatic field lines at the receptor and dielectric effects. Br J Pharmacol (1981) 1.10
Ionic dependence of adrenal steroidogenesis and ACTH-induced changes in the membrane potential of adrenocortical cells. J Physiol (1973) 1.07
Analysis of tissue amylase output by an automated method. Anal Biochem (1974) 1.06
Electrostatic components of drug-receptor recognition. I. Structural and sequence analogues of DNA polynucleotides. Proc R Soc Lond B Biol Sci (1980) 1.06
Photodynamic effects of erythrosine on the smooth muscle cells of guinea-pig taenia coli. Br J Pharmacol (1984) 1.06
Steroid production and membrane potential measurement in cells of the adrenal cortex. J Physiol (1967) 1.03
Automated site-directed drug design: the formation of molecular templates in primary structure generation. Proc R Soc Lond B Biol Sci (1989) 1.02
Release of neurohypophysial hormones by exocytosis. Nat New Biol (1973) 1.02
Ouabain-induced changes in the contractile and electrical activity, potassium content, and response to drugs, of smooth muscle cells. Can J Physiol Pharmacol (1967) 1.01
Investigation into the mode of action of histamine on the isolated rabbit heart. Br J Pharmacol Chemother (1968) 1.01
Drug-receptor recognition: molecular orientation and dielectric effects. Br J Pharmacol (1981) 1.00
The control of 86Rb efflux from rat isolated pancreatic islets by the sulphonylureas tolbutamide and glibenclamide. Br J Pharmacol (1984) 0.99
Recent advances in structure-based rational drug design. Curr Opin Struct Biol (2000) 0.99
The bioelectrical properties of pancreatic islet cells: effects of diabetogenic agents. Diabetologia (1972) 0.98
Hydration in drug design. 1. Multiple hydrogen-bonding features of water molecules in mediating protein-ligand interactions. J Comput Aided Mol Des (1995) 0.97
Calcium translocation and control mechanisms for endocrine secretion. Symp Soc Exp Biol (1979) 0.96
The impact of epilepsy surgery on quality of life in children. Neurology (2006) 0.96
Photosensitization of pancreatic tumour cells by delta-aminolaevulinic acid esters. Anticancer Drug Des (2000) 0.96
Exocytosis modelling: an electrostatic function for calcium in stimulus-secretion coupling. J Theor Biol (1975) 0.95
Cyclic GMP inhibits protein kinase C-mediated secretion in rat pancreatic acini. J Biol Chem (1988) 0.93
The calcium antagonistic effects of cyproheptadine on contraction, membrane electrical events and calcium influx in the guinea-pig taenia coli. Br J Pharmacol (1981) 0.92
The ionic dependence of the membrane potential and acetylcholine-induced depolarization of pancreatic acinar cells. J Physiol (1972) 0.92
Dynamic oscillations in the membrane potential of pancreatic islet cells. J Exp Biol (1979) 0.92
Automated site-directed drug design: a general algorithm for knowledge acquisition about hydrogen-bonding regions at protein surfaces. Proc R Soc Lond B Biol Sci (1989) 0.90
Automated site-directed drug design: the prediction and observation of ligand point positions at hydrogen-bonding regions on protein surfaces. Proc R Soc Lond B Biol Sci (1989) 0.90
Hydration in drug design. 2. Influence of local site surface shape on water binding. J Comput Aided Mol Des (1995) 0.89
Hydration in drug design. 3. Conserved water molecules at the ligand-binding sites of homologous proteins. J Comput Aided Mol Des (1995) 0.88
Membrane depolarization, cyclic AMP, and glycerol release by brown adipose tissue. Am J Physiol (1974) 0.87
Modification of the photodynamic action of delta-aminolaevulinic acid (ALA) on rat pancreatoma cells by mitochondrial benzodiazepine receptor ligands. Br J Cancer (1995) 0.86
Calcium exchangeability in subcellular fractions of pancreatic islet cells. J Cell Sci (1980) 0.85
Antagonism between strychnine and glycine, and bicuculline and GABA, in the ventromedial hypothalamus. Brain Res (1972) 0.85
Effect of ACTH on the electrical properties of adrenocortical cells. Nature (1968) 0.85
Modification of a Picker magnascanner to eliminate scalloping. Phys Med Biol (1969) 0.85
[Electrical activity in islet cells and insulin secretion]. Acta Diabetol Lat (1970) 0.85
Effects of a cytosolic protein on the interaction of rat pancreatic zymogen granules in vitro. Biochim Biophys Acta (1987) 0.85
Photodynamic drug action on isolated rat pancreatic acini. Mobilization of arachidonic acid and prostaglandin production. Biochem Pharmacol (1993) 0.85
Membrane potential changes of mouse adrenal zona fasciculata cells in response to adrenocorticotropin and adenosine 3',5'-monophosphate. Endocrinology (1982) 0.84
Efflux of 86Rb from rat and mouse pancreatic islets: the role of membrane depolarization. Br J Pharmacol (1984) 0.83
The London-Van der Waals attraction constant of secretory granules and its significance. J Theor Biol (1975) 0.83
Molecular surface-volume and property matching to superpose flexible dissimilar molecules. J Comput Aided Mol Des (1995) 0.83
An automated method for predicting the positions of hydrogen-bonding atoms in binding sites. J Comput Aided Mol Des (1997) 0.82
Electrostatic complementarity between proteins and ligands. 1. Charge disposition, dielectric and interface effects. J Comput Aided Mol Des (1994) 0.82
Biochemical and biophysical characterization of insulin granules isolated from rat pancreatic islets by an iso-osmotic gradient. Biochim Biophys Acta (1982) 0.82
Failure of the Bactec 460 radiometer to detect Cryptococcus neoformans fungemia in an AIDS patient. Am J Clin Pathol (1987) 0.82
[Proceedings: 27. Electrical characteristics of pancreatic islet cells of the mouse (author's transl)]. Nihon Seirigaku Zasshi (1974) 0.82
Design criteria for molecular mimics of fragments of the beta-turn. 1. C alpha atom analysis. J Comput Aided Mol Des (1999) 0.81
Calcium-ion binding to the chromaffin-granule surface. Biochem J (1974) 0.81
Particle motion in single acinar cells observed by microscope laser light scattering spectroscopy. Eur Biophys J (1987) 0.81
Automated site-directed drug design: the concept of spacer skeletons for primary structure generation. Proc R Soc Lond B Biol Sci (1989) 0.81
Calcium-dependent photodynamic action of di- and tetrasulphonated aluminium phthalocyanine on normal and tumour-derived rat pancreatic exocrine cells. Br J Cancer (1994) 0.80
A key role for the mitochondrial benzodiazepine receptor in cellular photosensitisation with delta-aminolaevulinic acid. Eur J Pharmacol (2000) 0.80
Evaluation of a method for controlling molecular scaffold diversity in de novo ligand design. J Comput Aided Mol Des (1997) 0.80
Effect of leukotriene C4 on electromechanical activity and Ca2+ uptake in taenia coli. Am J Physiol (1988) 0.79
The synaptic vesicle: calcium ion binding to the vesicle membrane and its modification by drug action. Mol Pharmacol (1976) 0.79
Permeabilization of thymocytes by photon activation of erythrosin. FEBS Lett (1987) 0.79
Effects of ions and metabolic inhibitors on membrane potential of brown adipose tissue. Am J Physiol (1974) 0.79
Inhibition of glucose-induced electrical activity in pancreatic islet cells by phloridzin, mannoheptulose, and anoxia. J Physiol (1973) 0.79
Molecular structure matching by simulated annealing. I. A comparison between different cooling schedules. J Comput Aided Mol Des (1990) 0.79
Electrostatic complementarity between proteins and ligands. 3. Structural basis. J Comput Aided Mol Des (1994) 0.78
The atom assignment problem in automated de novo drug design. 1. Transferability of molecular fragment properties. J Comput Aided Mol Des (1995) 0.78
Membrane depolarization, cyclic AMP and glycerol release by brown fat in vitro. J Physiol (1972) 0.78
Calcium and membrane permeability. Br Med Bull (1986) 0.78
Automated site-directed drug design: the generation of a basic set of fragments to be used for automated structure assembly. J Comput Aided Mol Des (1992) 0.78
The atom assignment problem in automated de novo drug design. 2. A method for molecular graph and fragment perception. J Comput Aided Mol Des (1995) 0.78
Automated site-directed drug design: an assessment of the transferability of atomic residual charges (CNDO) for molecular fragments. J Comput Aided Mol Des (1992) 0.78
Molecular structure matching by simulated annealing. III. The incorporation of null correspondences into the matching problem. J Comput Aided Mol Des (1991) 0.77
The atom assignment problem in automated de novo drug design. 5. Tests for envelope-directed fragment placement based on molecular similarity. J Comput Aided Mol Des (1995) 0.77
Molecular structure matching by simulated annealing. II. An exploration of the evolution of configuration landscape problems. J Comput Aided Mol Des (1990) 0.77
SLATE: a method for the superposition of flexible ligands. J Comput Aided Mol Des (2001) 0.77
The atom assignment problem in automated de novo drug design. 4. Tests for site-directed fragment placement based on molecular complementarity. J Comput Aided Mol Des (1995) 0.77
Electrostatic complementarity between proteins and ligands. 2. Ligand moieties. J Comput Aided Mol Des (1994) 0.77
Automated site-directed drug design: searches of the Cambridge Structural Database for bond lengths in molecular fragments to be used for automated structure assembly. J Comput Aided Mol Des (1992) 0.77
An exploration of a novel strategy for superposing several flexible molecules. J Comput Aided Mol Des (1993) 0.77
Design criteria for molecular mimics of fragments of the beta-turn. 2. C alpha-C beta bond vector analysis. J Comput Aided Mol Des (1999) 0.77
The effects of a photosensitive nitric oxide donor on basal and electrically-stimulated dopamine efflux from the rat striatum in vitro. Neuropharmacology (1994) 0.77
Automated method for following the production of corticosteroids by adrenal tissue in vitro. Can J Biochem (1967) 0.77