Published in J Am Chem Soc on January 24, 1973
Tautomeric states of the active-site histidines of phosphorylated and unphosphorylated IIIGlc, a signal-transducing protein from Escherichia coli, using two-dimensional heteronuclear NMR techniques. Protein Sci (1993) 2.61
The chemical and dynamical influence of the anti-viral drug amantadine on the M2 proton channel transmembrane domain. Biophys J (2007) 1.44
Assessing the fractions of tautomeric forms of the imidazole ring of histidine in proteins as a function of pH. Proc Natl Acad Sci U S A (2011) 1.07
The tautomeric state of histidines in myoglobin. Biophys J (1997) 0.96
pH-dependent random coil (1)H, (13)C, and (15)N chemical shifts of the ionizable amino acids: a guide for protein pK a measurements. J Biomol NMR (2014) 0.93
Measurement of histidine pKa values and tautomer populations in invisible protein states. Proc Natl Acad Sci U S A (2014) 0.92
Temperature dependence of histidine ionization constants in myoglobin. Biophys J (1997) 0.92
Conformational studies of oxytocin, lysine vasopressin, arginine vasopressin, and arginine vasotocin by carbon-13 nuclear magnetic resonance spectroscopy. Proc Natl Acad Sci U S A (1973) 0.91
Solid-state NMR and density functional theory studies of ionization states of thiamin. J Phys Chem B (2010) 0.90
A strong 13C chemical shift signature provides the coordination mode of histidines in zinc-binding proteins. J Biomol NMR (2012) 0.89
Histidine side-chain dynamics and protonation monitored by 13C CPMG NMR relaxation dispersion. J Biomol NMR (2009) 0.89
Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD domains. Acta Crystallogr D Biol Crystallogr (2009) 0.86
Structural investigations of the active-site mutant Asn156Ala of outer membrane phospholipase A: function of the Asn-His interaction in the catalytic triad. Protein Sci (2001) 0.86
Comparative structural analysis of cytidine, ethenocytidine and their protonated salts III. 1H, 13C and 15N NMR studies at natural isotope abundance. Nucleic Acids Res (1984) 0.85
Synthesis and copper(II)-binding properties of the N-terminal peptide of human alpha-fetoprotein. Biochem J (1989) 0.83
Proton affinity of the histidine-tryptophan cluster motif from the influenza A virus from ab initio molecular dynamics. Chem Phys (2013) 0.81
Modeling by assembly and molecular dynamics simulations of the low Cu2+ occupancy form of the mammalian prion protein octarepeat region: gaining insight into Cu2+-mediated beta-cleavage. Biophys J (2008) 0.80
The structure of DinB from Geobacillus stearothermophilus: a representative of a unique four-helix-bundle superfamily. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.80
Limiting values of the 15N chemical shift of the imidazole ring of histidine at high pH. J Phys Chem B (2012) 0.80
pH-dependence of 13C chemical shifts and 13C,H coupling constants in imidazole and L-histidine. Biochem J (1975) 0.78
Demystifying fluorine chemical shifts: electronic structure calculations address origins of seemingly anomalous (19)F-NMR spectra of fluorohistidine isomers and analogues. Phys Chem Chem Phys (2015) 0.76
Helix-Capping Histidines: Diversity of N-H···N Hydrogen Bond Strength Revealed by (2h)JNN Scalar Couplings. Biochemistry (2015) 0.75
The Biophysical Probes 2-fluorohistidine and 4-fluorohistidine: Spectroscopic Signatures and Molecular Properties. Sci Rep (2017) 0.75
Probing conformational dynamics in biomolecules via chemical exchange saturation transfer: a primer. J Biomol NMR (2017) 0.75
Site-selective (13)C labeling of histidine and tryptophan using ribose. J Biomol NMR (2017) 0.75
Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells. Nat Genet (1996) 3.08
Inactivation of Fac in mice produces inducible chromosomal instability and reduced fertility reminiscent of Fanconi anaemia. Nat Genet (1996) 2.32
An Alu element in the myeloperoxidase promoter contains a composite SP1-thyroid hormone-retinoic acid response element. J Biol Chem (1996) 1.92
Induction of increased calcium uptake in mouse T lymphocytes by concanavalin A and its modulation by cyclic nucleotides. Nature (1975) 1.82
Low-intensity hematopoietic stem-cell transplantation across human leucocyte antigen barriers in dyskeratosis congenita. Bone Marrow Transplant (2003) 1.80
A model of human acute lymphoblastic leukemia in immune-deficient SCID mice. Science (1989) 1.60
Acute changes in renal function associated with deferoxamine therapy. Am J Dis Child (1989) 1.59
Expression of glycolipid receptors to Shiga-like toxin on human B lymphocytes: a mechanism for the failure of long-lived antibody response to dysenteric disease. Int Immunol (1990) 1.45
Failure of recombinant human interleukin-3 therapy to induce erythropoiesis in patients with refractory Diamond-Blackfan anemia. Blood (1994) 1.45
Shwachman-Diamond syndrome: An inherited preleukemic bone marrow failure disorder with aberrant hematopoietic progenitors and faulty marrow microenvironment. Blood (1999) 1.45
Alternative donor bone marrow transplantation for children with juvenile myelomonocytic leukemia. J Pediatr Hematol Oncol (2000) 1.42
Thrombocytopenia with absent radii: frequency of marrow megakaryocyte progenitors, proliferative characteristics, and megakaryocyte growth and development factor responsiveness. Pediatr Hematol Oncol (2000) 1.40
Serial studies of auditory neurotoxicity in patients receiving deferoxamine therapy. Am J Med (1987) 1.39
Deferoxamine: a reversible S-phase inhibitor of human lymphocyte proliferation. Blood (1984) 1.36
Differential sensitivity of various pediatric cancers and squamous cell carcinomas to lovastatin-induced apoptosis: therapeutic implications. Clin Cancer Res (2001) 1.33
The consensus sequence of a major Alu subfamily contains a functional retinoic acid response element. Proc Natl Acad Sci U S A (1995) 1.31
Prevention of cardiac disease by subcutaneous deferoxamine in patients with thalassemia major. N Engl J Med (1985) 1.30
Juvenile myelomonocytic leukemia and Noonan syndrome. J Pediatr Hematol Oncol (2000) 1.30
Soluble antigen-antibody complexes as intermediates in the purification of antibodies in 8 molar urea. Arch Biochem Biophys (1966) 1.30
Immunohistochemical and genetic evidence of myeloperoxidase involvement in multiple sclerosis. J Neuroimmunol (1997) 1.27
5S rRNA gene transcription factor IIIA alters the helical configuration of DNA. Proc Natl Acad Sci U S A (1983) 1.27
Carbon-13 nuclear magnetic resonance titration shifts in amino acids. J Am Chem Soc (1974) 1.26
Shwachman syndrome: exocrine pancreatic dysfunction and variable phenotypic expression. Gastroenterology (1996) 1.25
Increased sensitivity of acute myeloid leukemias to lovastatin-induced apoptosis: A potential therapeutic approach. Blood (1999) 1.24
Immune function in patients with Shwachman-Diamond syndrome. Br J Haematol (2001) 1.21
The effects of complete modification of amino groups on the antibody activity of antihapten antibodies. Reversible inactivation with maleic anhydride. Biochemistry (1968) 1.19
In vitro and in vivo effects of deferoxamine in neonatal acute leukemia. Blood (1987) 1.13
Limonoids from Swietenia macrophylla and S. aubrevilleana. J Nat Prod (1999) 1.11
Differences in susceptibility of human cells to mouse sarcoma virus. J Natl Cancer Inst (1971) 1.11
Diamond-blackfan anemia: etiology, pathophysiology, and treatment. Am J Pediatr Hematol Oncol (1989) 1.06
Fanconi's anaemia and pregnancy. Br J Haematol (1991) 1.05
The morbidity and mortality of splenectomy in childhood. Ann Surg (1977) 1.04
Shwachman-Diamond syndrome marrow cells show abnormally increased apoptosis mediated through the Fas pathway. Blood (2001) 1.04
Comparison of oral iron chelator L1 and desferrioxamine in iron-loaded patients. Lancet (1990) 1.03
Autoerythrocyte sensitization. J Pediatr (1983) 1.02
Effect of altitude exposure on platelets. J Appl Physiol (1975) 1.01
Early biochemical events in lymphocyte activation. I. Investigations on the nature and significance of early calcium fluxes observed in mitogen-induced T and B lymphocytes. Cell Immunol (1979) 1.01
The use of preparative liquid isoelectric focusing for the further purification of rabbit antihapten antibodies. J Immunol Methods (1972) 1.00
Carbon-13 nuclear-magnetic-resonance studies on selected amino acids, peptides, and proteins. Eur J Biochem (1973) 0.99
The Xenopus YB3 protein binds the B box element of the class III promoter. Nucleic Acids Res (1991) 0.99
Regulation of interferon receptor expression in human blood lymphocytes in vitro and during interferon therapy. J Clin Invest (1986) 0.96
Effect of age at the start of iron chelation therapy on gonadal function in beta-thalassemia major. N Engl J Med (1990) 0.96
Phase III randomized, double-blind placebo-controlled trial of rhGM-CSF following allogeneic bone marrow transplantation. Bone Marrow Transplant (1995) 0.96
Management of intracerebral hemorrhage in idiopathic thrombocytopenic purpura. Report of four cases. J Neurosurg (1976) 0.95
Novel point mutation in the extracellular domain of the granulocyte colony-stimulating factor (G-CSF) receptor in a case of severe congenital neutropenia hyporesponsive to G-CSF treatment. J Exp Med (1999) 0.95
Bone marrow from children in relapse with pre-B acute lymphoblastic leukemia proliferates and disseminates rapidly in scid mice. Blood (1991) 0.95
Interleukin 6 induces myeloid differentiation of a human biphenotypic leukemic cell line. Leuk Res (1992) 0.94
Growth failure and bony changes induced by deferoxamine. Am J Pediatr Hematol Oncol (1992) 0.94
Patterns of hematopoietic lineage involvement in children with neurofibromatosis type 1 and malignant myeloid disorders. Blood (1996) 0.94
Transient erythroblastopenia of childhood: varied pathogenesis. Am J Hematol (1983) 0.94
Mice lacking myeloperoxidase are more susceptible to experimental autoimmune encephalomyelitis. J Neuroimmunol (2001) 0.94
Juvenile chronic myelogenous leukemia: characterization of the disease using cell cultures. Blood (1986) 0.93
Molecular dynamics and structure of the random coil and helical states of the collagen peptide, alpha 1-CB2, as determined by 13C magnetic resonance. Biochemistry (1975) 0.93
Hematopoiesis in the human spleen. Am J Hematol (1981) 0.92
Isolation and characterization of electrophoretically homogeneous rabbit antihapten antibody populations. I. Separation and properties of homogeneous anti-p-azophenyltrimethyl-ammonium antibodies. J Biol Chem (1971) 0.92
A rapid technique for measuring calcium uptake in mitogen-induced T and B lymphocytes. Can J Biochem (1979) 0.92
Yersinia sepsis in patients with iron overload treated with deferoxamine. N Engl J Med (1986) 0.92
Recovery of specific activity upon reoxidation of completely reduced polyalanyl rabbit antibody. J Biol Chem (1966) 0.92
Erythroid colony growth in congenital hypoplastic anemia. J Clin Invest (1976) 0.92
Autocrine interleukin-1beta production in leukemia: evidence for the involvement of mutated RAS. Cancer Res (1999) 0.91
Preparation and studies of 19 F-labeled and enriched 13 C-labeled semisynthetic ribonuclease-S' analogues. J Biol Chem (1973) 0.91
In vitro production of an amyloid-like substance from gamma 3 heavy chain disease protein. Immunol Commun (1974) 0.90
Diamond-Blackfan syndrome: evidence against cell-mediated erythropoietic suppression. Blood (1978) 0.90
High field carbon-13 NMR spectroscopy. Conformational mobility in gramicidin S and frequency dependence of 13-C spin-lattice relaxation times. Biochem Biophys Res Commun (1975) 0.89
Severe acquired aplastic anemia in children: 11-year experience with bone marrow transplantation and immunosuppressive therapy. Am J Pediatr Hematol Oncol (1989) 0.89
Identification of human juvenile chronic myelogenous leukemia stem cells capable of initiating the disease in primary and secondary SCID mice. Blood (1996) 0.89
Adenovirus-mediated p53 gene therapy in osteosarcoma cell lines: sensitization to cisplatin and doxorubicin. Cancer Gene Ther (2006) 0.89
Proctoriones A-C: 2-acylcyclohexane-1,3-dione derivatives from peperomia proctorii. J Nat Prod (2000) 0.88
The value of intensive combination chemotherapy for juvenile chronic myelogenous leukemia. J Clin Oncol (1987) 0.88
Relationship of DNA topoisomerase II alpha and beta expression to cytotoxicity of antineoplastic agents in human acute lymphoblastic leukemia cell lines. Cancer Res (1995) 0.87
Combined corticosteroid/granulocyte colony-stimulating factor (G-CSF) therapy in the treatment of severe congenital neutropenia unresponsive to G-CSF: Activated glucocorticoid receptors synergize with G-CSF signals. Exp Hematol (2000) 0.87
Torsional stress induces an S1 nuclease-hypersensitive site within the promoter of the Xenopus laevis oocyte-type 5S RNA gene. Proc Natl Acad Sci U S A (1985) 0.87
Constitutive expression and role in growth regulation of interleukin-1 and multiple cytokine receptors in a biphenotypic leukemic cell line. Blood (1991) 0.87
Differentiation of murine marrow megakaryocyte progenitors (CFUm): humoral control in vitro. Cell Tissue Kinet (1981) 0.86
Molecular mobility of polypeptides containing proline as determined by 13C magnetic resonance. Biopolymers (1974) 0.86
Spectral assignment and conformational analysis of cyclic peptides by carbon-13 nuclear magnetic resonance. J Biol Chem (1972) 0.86
Participation of amino groups in the active sites of antibodies. Immunochemistry (1968) 0.85
Detection of residual acute lymphoblastic leukemia cells in cultures of bone marrow obtained during remission. N Engl J Med (1986) 0.85
In vitro cytoprotective activity of squalene on a bone marrow versus neuroblastoma model of cisplatin-induced toxicity. implications in cancer chemotherapy. Eur J Cancer (2003) 0.85
Relative efficacy of amethocaine gel and lidocaine-prilocaine cream for Port-a-Cath puncture in children. Pediatrics (1999) 0.85
Malignant myeloid transformation with isochromosome 7q in Shwachman-Diamond syndrome. Leukemia (1998) 0.84
Management of Kostmann syndrome in the G-CSF era. Br J Haematol (2000) 0.84
Single-centre experience with allogeneic bone marrow transplantation for acute lymphoblastic leukaemia in childhood: similar survival after matched-related and matched-unrelated donor transplants. Br J Haematol (2002) 0.84
New diterpenes from Jatropha divaricata. J Nat Prod (2001) 0.84
Allogeneic bone marrow transplantation vs chemotherapy for children with Philadelphia chromosome-positive acute lymphoblastic leukemia. Bone Marrow Transplant (2004) 0.84
Constitutional aplastic anaemia: defective haematopoietic stem cell growth in vitro. Br J Haematol (1978) 0.84
An unusual sesquiterpene derivative from the Caribbean gorgonian Pseudopterogorgia rigida. J Nat Prod (2000) 0.84
Control of 5S RNA transcription in Xenopus somatic cell chromatin: activation with an oocyte extract. Nucleic Acids Res (1983) 0.84
p53 gene status and chemosensitivity of childhood acute lymphoblastic leukemia cells to adriamycin. Leuk Res (1999) 0.84
Early discharge of pediatric febrile neutropenic cancer patients by substitution of oral for intravenous antibiotics. Pediatr Hematol Oncol (1994) 0.83
Molecular mobility and structure of elastin deduced from the solvent and temperature dependence of 13C magnetic resonance relaxation data. Biochemistry (1975) 0.83
Long-term bone marrow cultures in Diamond-Blackfan anemia reveal a defect of both granulomacrophage and erythroid progenitors. Exp Hematol (1999) 0.83