Published in J Clin Invest on August 01, 1973
Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1 alpha. Proc Natl Acad Sci U S A (2002) 2.35
Reduced subjective awareness of bronchoconstriction provoked by methacholine in elderly asthmatic and normal subjects as measured on a simple awareness scale. Thorax (1992) 2.11
Effect of aging on respiratory system physiology and immunology. Clin Interv Aging (2006) 2.08
Respiratory impairment and the aging lung: a novel paradigm for assessing pulmonary function. J Gerontol A Biol Sci Med Sci (2011) 1.28
Obstructive sleep apnea in older adults is a distinctly different physiological phenotype. Sleep (2014) 1.20
Assessment and management of acute asthma in the elderly: a comparison with younger asthmatics. Postgrad Med J (1982) 1.19
Effects of hypermetabolism on ventilation and chemosensitivity. J Clin Invest (1977) 1.10
Sex steroidal hormones and respiratory control. Respir Physiol Neurobiol (2008) 1.03
Chemical control stability in the elderly. J Physiol (2007) 1.02
Effects of hypercapnia and inspiratory flow-resistive loading on respiratory activity in chronic airways obstruction. J Clin Invest (1977) 1.00
Idiopathic scoliosis. Mechanical properties of the respiratory system and the ventilatory response to carbon dioxide. J Clin Invest (1975) 0.98
Idiopathic scoliosis. Gas exchange and the age dependence of arterial blood gases. J Clin Invest (1976) 0.92
Antioxidants reverse depression of the hypoxic ventilatory response by acetazolamide in man. J Physiol (2006) 0.90
Respiratory function in the elderly and the effects of beta blockade. Cardiovasc Drugs Ther (1991) 0.89
Hypoxic and hypercapnic ventilatory responses in aging male vs. aging female rats. J Appl Physiol (1985) (2009) 0.89
Lung disease at high altitude. Expert Rev Respir Med (2009) 0.86
Ageing and cardiorespiratory response to hypoxia. J Physiol (2012) 0.86
Aging blunts hyperventilation-induced hypocapnia and reduction in cerebral blood flow velocity during maximal exercise. Age (Dordr) (2011) 0.85
Optical imaging in an Alzheimer's mouse model reveals amyloid-β-dependent vascular impairment. Neurophotonics (2014) 0.85
Cardiac mechanics are impaired during fatiguing exercise and cold pressor test in healthy older adults. J Appl Physiol (1985) (2012) 0.84
Ventilatory and heart rate responses to hypoxia and hypercapnia in patients with diabetes mellitus. Thorax (1989) 0.83
Short- and long-term modulation of the exercise ventilatory response. Med Sci Sports Exerc (2010) 0.81
Correlates of obstructive apnea duration. Lung (2013) 0.80
Characteristics of hyperthermia-induced hyperventilation in humans. Temperature (Austin) (2016) 0.78
Ascorbic acid does not enhance hypoxia-induced vasodilation in healthy older men. Physiol Rep (2014) 0.78
Hypoxic ventilatory response in subjects with normal and high oxygen affinity hemoglobins. J Clin Invest (1977) 0.78
Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine. Clin Pharmacokinet (2017) 0.76
Carotid body function in aged rats: responses to hypoxia, ischemia, dopamine, and adenosine. Age (Dordr) (2010) 0.76
Age-related reflex responses from peripheral and central chemoreceptors in healthy men. Clin Auton Res (2014) 0.76
Noninvasive quantification of alveolar morphometry in elderly never- and ex-smokers. Physiol Rep (2015) 0.75
Cardiovascular function during sleep apnoeas. Postgrad Med J (1989) 0.75
Age-dependent differences in the positive inotropic effect of phenylephrine on rat isolated atria. Br J Pharmacol (1983) 0.75
Lower hypoxic ventilatory response in smokers compared to non-smokers during abstinence from cigarettes. BMC Pulm Med (2016) 0.75
Lung cancer in elderly patients. J Thorac Dis (2016) 0.75
Effect of acute hypoxia on muscle blood flow, VO₂p, and [HHb] kinetics during leg extension exercise in older men. Eur J Appl Physiol (2013) 0.75
Effects of lumbar puncture position on arterial blood gases. J Anesth (1994) 0.75
The Veterans Administration-Army cooperative study of pulmonary function. I. Clinical spirometry in normal men. Am J Med (1961) 10.82
A clinical method for assessing the ventilatory response to carbon dioxide. Australas Ann Med (1967) 5.61
Elasticity of human lungs in relation to age. J Appl Physiol (1968) 2.47
Chemoreflexes in breathing. Physiol Rev (1962) 2.32
CORONARY HEART DISEASE AMONG MINNESOTA BUSINESS AND PROFESSIONAL MEN FOLLOWED FIFTEEN YEARS. Circulation (1963) 2.13
A-a difference in O2 tension and physiological dead space in normal man. J Appl Physiol (1963) 2.12
Effect of carotid endarterectomy on carotid chemoreceptor and baroreceptor function in man. N Engl J Med (1970) 1.97
Respiratory insensitivity to hypoxia in chronically hypoxic man. Respir Physiol (1966) 1.79
Hypoxic ventilatory drive in normal man. J Clin Invest (1970) 1.62
The alveolar-arterial oxygen difference: its size and components in normal man. Acta Physiol Scand (1966) 1.57
Effect of bilateral carotid-body resection on ventilatory control at rest and during exercise in man. N Engl J Med (1971) 1.55
The effect of carbon dioxide on the respiratory response to want of oxygen in man. Q J Exp Physiol Cogn Med Sci (1957) 1.41
The respiratory response to carbon dioxide in health and in emphysema. J Clin Invest (1960) 1.33
Irreversible respiratory insensitivity to acute hypoxia in man born at high altitude. J Appl Physiol (1968) 1.31
The ventilatory response to CO2 in chronic airways obstruction measured by a rebreathing method. Clin Sci (1968) 1.27
The elastic properties of the lungs in the aged. J Lab Clin Med (1958) 1.22
Respiratory insensitivity to acute hypoxia persisting after correction of tetralogy of Fallot. J Appl Physiol (1968) 1.21
Ventilatory response to a single breath of CO2 in O2 in normal man at sea level and high altitude. J Appl Physiol (1969) 1.14
Acquired attenuation of chemoreceptor function in chronically hypoxic man at high altitude. J Clin Invest (1971) 1.14
The influence of age, sex, body size and lung size on the control and pattern of breathing during CO 2 inhalation in Caucasians. Respir Physiol (1972) 1.13
Ventilatory control in the athlete. J Appl Physiol (1971) 1.08
Comparison of three methods for quantitating respiratory response to hypoxia in man. Respir Physiol (1972) 1.01
The blunted ventilatory response to hypoxia in cyanotic congenital heart disease. N Engl J Med (1970) 1.01
[Effect of oxygen pressure in inspired air on respiratory activity of the human, tested under the constant behavior of alveolar carbon dioxide pressure]. Pflugers Arch (1958) 0.99
Chemoreflex ventilatory response to CO 2 in man at low and high altitudes. Respir Physiol (1972) 0.98
Effect of chronic exposure to hypoxia on ventilatory response to CO 2 and hypoxia. J Appl Physiol (1971) 0.96
Hypoxic and hypercapnic ventilatory drives in children native to high altitude. J Appl Physiol (1972) 0.96
Static pressure-volume characteristics of lungs in normal males. J Appl Physiol (1960) 0.94
Lung diffusing capacity. Normal values in male smokers and non-smokers using the breath-holding technique. Scand J Respir Dis (1970) 0.92
Irreversible blunted respiratory sensitivity to hypoxia in high altitude natives. Respir Physiol (1969) 0.87
End-tidal gas sampler. J Appl Physiol (1970) 0.83
Complement and leukocyte-mediated pulmonary dysfunction in hemodialysis. N Engl J Med (1977) 3.43
Complement activation and pulmonary leukotasis during nylon fiber filtration leukapheresis. Blood (1978) 1.52
Human llamas: adaptation to altitude in subjects with high hemoglobin oxygen affinity. J Clin Invest (1978) 1.08
Clinical features of acute pulmonary blastomycosis. N Engl J Med (1974) 1.04
The usefulness of bronchoalveolar lavage in identifying past occupational exposure to asbestos: a light and electron microscopy study. Am J Ind Med (1991) 0.98
The distribution of nebulized isoproterenol and its effect of regional ventilation and perfusion. Am Rev Respir Dis (1974) 0.92
Vital capacity breaths of 5 percent or 15 percent CO 2 in N 2 or O 2 to test carotid chemosensitivity. Respir Physiol (1973) 0.91
Ventilatory and heart rate responses to hypoxia and hypercapnia during sleep in adults. J Appl Physiol Respir Environ Exerc Physiol (1982) 0.88
Flurazepam attenuates the arousal response to CO2 during sleep in normal subjects. Am Rev Respir Dis (1983) 0.88
Letter: The use of oral diazepam in patients with obstructive lung disease and hypercapnia. Ann Intern Med (1975) 0.88
Increased hypoxic ventilatory drive due to administration of aminophylline in normal men. Chest (1980) 0.87
Effects of acetazolamide and hypoxia on cerebrospinal fluid bicarbonate. J Appl Physiol (1968) 0.85
Chronic obstructive pulmonary disease: a community-oriented program including professional education and screening by a voluntary health agency. Am Rev Respir Dis (1980) 0.83
Severe complications of intravenous phytonadione therapy. Two cases, with one fatality. Postgrad Med (1982) 0.82
Reduced diffusing capacity as an isolated finding in asbestos- and silica-exposed workers. Chest (1990) 0.82
Normal chemoreceptor function in obesity before and after ileal bypass surgery to force weight reduction. Am J Med (1975) 0.81
Pulmonary artery pressure and alveolar gas exchange in man during acclimatization to 12,470 ft. J Clin Invest (1971) 0.80
Upper airway obstruction during head flexion in Morquio's disease. Am J Med (1980) 0.80
Effects of acetazolamide on physiologic and subjective responses of men to 14,000 feet. SAM-TR-67-81. Tech Rep SAM-TR (1967) 0.80
Hastening respiratory acclimatization to altitude with benzolamide (CL 11,366). Aerosp Med (1968) 0.80
Pneumocystis carinii pneumonia. Needle-biopsy diagnosis and successful treatment. JAMA (1968) 0.79
Pulmonary disease associated with L-tryptophan-induced eosinophilic myalgia syndrome. Clinical and pathologic features. Chest (1990) 0.79
Effects of chronic administration of codeine and promethazine on breathlessness and exercise tolerance in patients with chronic airflow obstruction. Br J Dis Chest (1987) 0.78
Airflow obstruction in nonsmoking, asbestos- and mixed dust-exposed workers. Lung (1993) 0.78
Acute respiratory failure and obesity with normal ventilatory response to carbon dioxide and absent hypoxic ventilatory drive. Am J Med (1977) 0.78
Hypoxic ventilatory response in subjects with normal and high oxygen affinity hemoglobins. J Clin Invest (1977) 0.78
Altered cerebral inhibition of respiratory and cardiac responses to hypercapnia in acute stroke. Neurology (1980) 0.77
Chemical regulation of respiration. Normal variations and abnormal responses. Chest (1982) 0.77
Con: antibiotic use in exacerbations of chronic bronchitis. Semin Respir Infect (1993) 0.77
Pulmonary toxicity recurring after a six week course of busulfan therapy and after subsequent therapy with uracil mustard. Chest (1978) 0.77
Frequency dependence of regional lung clearance of 133Xe in normal men. Respir Physiol (1976) 0.77
Study of the surface secretion of the bronchiole using radioautography. Am Rev Respir Dis (1976) 0.76
The value of bronchoscopy in establishing the etiology of pneumonia in renal transplant recipients. Am Rev Respir Dis (1982) 0.76
Hemoglobin oxygen affinity and adaptation to altitude: evidence for pre-adaptation to altitude in humans with left-shifted oxyhemoglobin dissociation curves. Trans Assoc Am Physicians (1978) 0.75
Effect of a nonlactose diet on human intestinal disaccharidase activity. Am J Dig Dis (1968) 0.75
Attenuated responses to CO2 and hypoxia in parents of threatened sudden infant death syndrome infants. Chest (1981) 0.75
The effect of age on regional lung ventilation and perfusion. J Lab Clin Med (1971) 0.75
Lung scanning and age. Ann Intern Med (1972) 0.75
Hastening respiratory acclimatization to altitude with benzolamide. SAM-TR-67-98. Tech Rep SAM-TR (1967) 0.75
Treatment of altitude dysbarism with oxygen under high pressure; report of three cases. Aerosp Med (1966) 0.75
Adult respiratory distress syndrome due to salicylate intoxication. Minn Med (1982) 0.75
Screening for early obstruction of the airways: a 1978 reappraisal. Chest (1978) 0.75
Insensible weight and water loss during simulated space flight. Aerosp Med (1968) 0.75
Ventilatory response to carbon dioxide inhalation in acute ischemic cerebral infarction. Trans Am Neurol Assoc (1975) 0.75
Acute respiratory failure in chronic obstructive lung disease and its treatment. Postgrad Med (1970) 0.75
Cavitating coccidioidomycosis complicated by a second cavitating pneumonia. Minn Med (1981) 0.75
The effect of aging on lung perfusion. Ann Intern Med (1972) 0.75
Chronic bronchitis. Choosing the optimal treatment. Postgrad Med (1993) 0.75
Acute myeloid leukemia: treatment of with 6-mercaptopurine and cyclophosphamide. Minn Med (1966) 0.75
Dual camera studies of pulmonary function with computer processing of data. Am J Roentgenol Radium Ther Nucl Med (1974) 0.75
Utilization of humans with high oxygen affinity hemoglobins in identifying mediators of physiologic responses to hypoxia. Prog Clin Biol Res (1978) 0.75
Invisible gas: who's liable? Tex Med (1993) 0.75
The effect of age on the distribution of ventilation and perfusion in the lung. Am Rev Respir Dis (1973) 0.75
Acetazolamide for acute mountain sickness. N Engl J Med (1969) 0.75
Occupational lung cancer. Mayo Clin Proc (1993) 0.75