Published in Biochem J on April 01, 1973
The oxoacyl-coenzyme A thiolases of animal tissues. Biochem J (1973) 1.85
The estimation of rates of utilization of glucose and ketone bodies in the brain of the suckling rat using compartmental analysis of isotopic data. Biochem J (1974) 1.22
Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation. J Biol Chem (2013) 1.20
Development of mitochondrial energy metabolism in rat brain. Biochem J (1977) 1.16
beta-Hydroxybutyrate fuels synaptic function during development. Histological and physiological evidence in rat hippocampal slices. J Clin Invest (1998) 1.00
Ketone-body metabolism in glioma and neuroblastoma cells. Proc Natl Acad Sci U S A (1981) 0.96
Differential substrate oxidation by dissociated brain cells and homogenates during development. Biochem J (1983) 0.90
The contribution of ketone bodies to basal and activity-dependent neuronal oxidation in vivo. J Cereb Blood Flow Metab (2014) 0.87
Effect of pH on binding of agonists and antagonists to rat heart muscarinic receptors. Biochem J (1983) 0.84
Acetoacetate metabolism in rat brain. Development of acetoacetyl-coenzyme A deacylase and 3-hydroxy-3-methylglutaryl-coenzyme A synthase. Biochem J (1978) 0.82
Effects of starvation and development on mitochondrial acetoacetyl-coenzyme A thiolase of rat liver. Biochem J (1977) 0.80
Influence of neonatal hypothyroidism on the development of ketone-body-metabolizing enzymes in rat brain. Biochem J (1979) 0.80
Effect of phenylalanine metabolites on the activities of enzymes of ketone-body utilization in brain of suckling rats. Biochem J (1976) 0.80
Neuropathologic changes in suckling and weanling rats with pyrithiamine-induced thiamine deficiency. Acta Neuropathol (1983) 0.75
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue. Biochem J (1955) 38.61
The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation. J Anat (1962) 8.63
Activities of enzymes involved in acetoacetate utilization in adult mammalian tissues. Biochem J (1971) 3.48
Changes in D(--)-beta-hydroxybutyric dehydrogenase activity during brain maturation in the rat. J Biol Chem (1967) 2.55
Activities of enzymes of ketone-body utilization in brain and other tissues of suckling rats. Biochem J (1971) 2.44
The metabolism of rat brain mitochondria. Preparation and characterization. J Biol Chem (1970) 2.37
LACTATE DEHYDROGENASE AS A CYTOPLASMIC MARKER IN BRAIN. Biochem J (1963) 2.00
The oxoacyl-coenzyme A thiolases of animal tissues. Biochem J (1973) 1.85
Coenzyme A transferase activity in rat brain. Biochem Biophys Res Commun (1971) 1.36
Acetoacetyl--coenzyme A thiolase in brain, liver, and kidney during maturation of the rat. Science (1971) 1.03
Ketone body enzymes in mammalian tissues. Effect of high fat diet. J Biol Chem (1971) 0.89
A free-text processing system to capture physical findings: Canonical Phrase Identification System (CAPIS). Proc Annu Symp Comput Appl Med Care (1991) 4.22
Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology. Proteomics (2001) 3.02
A free-text processing system to capture physical findings: Canonical Phrase Identification System (CAPIS). Proc Annu Symp Comput Appl Med Care (1991) 2.96
Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice. Nat Med (1996) 2.35
Quorum sensing and the population-dependent control of virulence. Philos Trans R Soc Lond B Biol Sci (2000) 2.17
The oxoacyl-coenzyme A thiolases of animal tissues. Biochem J (1973) 1.85
Reuse of knowledge represented in the Arden syntax. Proc Annu Symp Comput Appl Med Care (1992) 1.57
Synthesis of multiple N-acylhomoserine lactones is wide-spread among the members of the Burkholderia cepacia complex. Syst Appl Microbiol (2001) 1.54
Probabilistic diagnosis using a reformulation of the INTERNIST-1/QMR knowledge base. I. The probabilistic model and inference algorithms. Methods Inf Med (1991) 1.52
Human liver long-chain 3-hydroxyacyl-coenzyme A dehydrogenase is a multifunctional membrane-bound beta-oxidation enzyme of mitochondria. Biochem Biophys Res Commun (1992) 1.48
A coenzyme A analogue, desulpho-coA; preparation and effects on various enzymes. Biochem Biophys Res Commun (1966) 1.42
Evaluating consensus among physicians in medical knowledge base construction. Methods Inf Med (1993) 1.41
Modulating the potency of an activator in a yeast in vitro transcription system. Mol Cell Biol (1994) 1.27
The kinetic mechanism of 3-hydroxy-3-methylglutaryl-coenzyme A synthase from baker's yeast. Biochem J (1972) 1.23
Beta-ketothiolase deficiency in a family confirmed by in vitro enzymatic assays in fibroblasts. Eur J Pediatr (1982) 1.19
Measuring the quality of medical records: a method for comparing completeness and correctness of clinical encounter data. Proc AMIA Symp (2001) 1.18
The kinetic mechanism and properties of the cytoplasmic acetoacetyl-coenzyme A thiolase from rat liver. Biochem J (1974) 1.15
Inhibition of hepatic cholesterol synthesis and S-3-hydroxy-3-methylglutaryl-CoA reductase by mono and bicyclic monoterpenes administered in vivo. Biochem Pharmacol (1980) 1.11
The purification and some properties of 3-hydroxy-3-methylglutaryl-coenzyme A synthase from Baker's yeast. Biochem J (1972) 1.11
The mitochondrial trifunctional protein: centre of a beta-oxidation metabolon? Biochem Soc Trans (2000) 1.10
The existence of ketoacyl-CoA thiolases of differing properties and intracellular localization in ox liver. Biochem Biophys Res Commun (1972) 1.09
3-Oxothiolase activities and [14C]-2-methylbutanoic acid incorporation in cultured fibroblasts from 13 cases of suspected 3-oxothiolase deficiency. Pediatr Res (1990) 1.09
Extraocular light exposure does not suppress plasma melatonin in humans. J Clin Endocrinol Metab (1998) 1.06
The mechanism of inhibition of beta-oxidation by aspirin metabolites in skin fibroblasts from Reye's syndrome patients and controls. Biochim Biophys Acta (1999) 1.06
Succinyl-CoA:3-ketoacid CoA-transferase deficiency. Pediatrics (1998) 1.05
Effects of hypothyroidism and high-fat feeding on mRNA concentrations for the low-density-lipoprotein receptor and on acyl-CoA:cholesterol acyltransferase activities in rat liver. Biochem J (1991) 1.02
3-Ketoacyl-CoA thiolases of mammalian tissues. Methods Enzymol (1975) 1.02
Efficacy of melatonin treatment in jet lag, shift work, and blindness. J Biol Rhythms (1997) 0.96
The existence of an inner-membrane-bound, long acyl-chain-specific 3-hydroxyacyl-CoA dehydrogenase in mammalian mitochondria. Biochim Biophys Acta (1982) 0.96
Infectious Th1 and Th2 autoimmunity in diabetes-prone mice. Immunol Rev (1998) 0.95
Subcellular distribution of 3-hydroxy-3-methylglutaryl-CoA synthase, acetoacetyl-CoA thiolase and NAD kinase in Saccharomyces cerevisiae. Biochim Biophys Acta (1969) 0.95
The synthesis and characterisation of 2-methylacetoacetyl coenzyme A and its use in the identification of the site of the defect in 2-methylacetoacetic and 2-methyl-3-hydroxybutyric aciduria. Clin Chim Acta (1983) 0.94
Adjunct to bile-acid treatment for gall-stone dissolution: low-dose chenodeoxycholic acid combined with a terpene preparation. Br Med J (Clin Res Ed) (1981) 0.94
Antihypertensive medication-taking. Investigation of a simple regimen. Am J Hypertens (1993) 0.93
Factors associated with the elderly falling in intermediate care facilities. Drug Intell Clin Pharm (1985) 0.92
An enzyme-bound intermediate in the biosynthesis of 3-hydroxy-3-methylglutaryl-coenzyme A. Biochem J (1974) 0.92
beta-Ketothiolase deficiency with favourable evolution. J Inherit Metab Dis (1987) 0.91
Circadian phase assessment by ambulatory monitoring in humans: correlation with dim light melatonin onset. Chronobiol Int (2013) 0.90
A study of the metabolism of [U-14C]3-methyl-2-oxopentanoate by rat liver mitochondria using h.p.l.c. with continuous on-line monitoring of radioactive intact acyl-coenzyme A intermediates. Biochem J (1986) 0.89
The mechanism of cyclic monoterpene inhibition of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase in vivo in the rat. J Biol Chem (1982) 0.89
The inhibition of hepatic S-3-hydroxy-3-methylglutaryl-CoA reductase by 3,3,5-trimethylcyclohexanol and its mandelic acid ester, cyclandelate. Biochem Pharmacol (1983) 0.88
Complex effects of melatonin: evidence for photoperiodic responses in humans? Sleep (1999) 0.88
Reye syndrome--insights on causation and prognosis. Arch Dis Child (2001) 0.88
3-Ketothiolase deficiency. Eur J Pediatr (1986) 0.87
Differential diagnosis of hydroxydicarboxylic aciduria based on release of 3H2O from [9,10-3H]myristic and [9,10-3H]palmitic acids by intact cultured fibroblasts. J Inherit Metab Dis (1992) 0.86
Dietary cyclandelate decreases pre-established atherosclerosis in the rabbit. Atherosclerosis (1984) 0.86
Long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency--diagnosis, plasma carnitine fractions and management in a further patient. Eur J Pediatr (1993) 0.85
Comparison of Computer-based Clinical Decision Support Systems and Content for Diabetes Mellitus. Appl Clin Inform (2011) 0.85
Biochemical investigations on a patient with a defect in cytosolic acetoacetyl-CoA thiolase, associated with mental retardation. J Inherit Metab Dis (1984) 0.84
Dietary vitamin A and cancer--a multisite case-control study. Nutr Cancer (1986) 0.83
In vivo inhibition of hepatic lipogenesis in the rat by cyclandelate (3,3',5-trimethylcyclohexanylmandelate). Biochem Pharmacol (1983) 0.83
Cholesterol esterification plays a major role in determining low-density-lipoprotein receptor activity in primary monolayer cultures of rat hepatocytes. Biochem J (1989) 0.82
Hyperketotic states due to inherited defects of ketolysis. Enzyme (1987) 0.82
The control of sterol synthesis during development of rabbit mammary gland. J Biol Chem (1981) 0.82
Regulation of dolichol and of cholesterol biosynthesis in cholesterol-fed rabbits. Arch Biochem Biophys (1981) 0.80
Rowachol, a proprietary terpene preparation, dissolves cholesterol gallstones [proceedings]. Br J Clin Pharmacol (1978) 0.80
Inhibition of cellular cholesterol esterification can decrease low density lipoprotein receptor number in human fibroblasts. Biochem Biophys Res Commun (1987) 0.80
The effect of cyclandelate on cholesterol synthesis. Br J Clin Pract Suppl (1984) 0.80
Elevation of cyclic AMP by iloprost and prostaglandin E1 increases cholesterol efflux and the binding capacity for high-density lipoproteins in human fibroblasts. Biochim Biophys Acta (1998) 0.79
An hour of bright white light in the early morning improves performance and advances sleep and circadian phase during the Antarctic winter. Neurosci Lett (2012) 0.79
Diagnosis and prevalence of Leporacarus gibbus in the fur of domestic rabbits in the UK. Vet Rec (1998) 0.79
Disturbances in melatonin and core body temperature circadian rhythms after minimal invasive surgery. Acta Anaesthesiol Scand (2007) 0.78
Sleep and circadian rhythms in hospitalized patients with decompensated cirrhosis: effect of light therapy. Neurochem Res (2014) 0.78
Validation of an innovative method, based on tilt sensing, for the assessment of activity and body position. Chronobiol Int (2015) 0.78
Purification of long-chain 3-hydroxyacyl-CoA dehydrogenase from human infant liver. Prog Clin Biol Res (1992) 0.78
Two cases of beta-ketothiolase deficiency: a comparison. J Inherit Metab Dis (1984) 0.78
Characterisation of a novel enzyme of human fatty acid beta-oxidation: a matrix-associated, mitochondrial 2-enoyl-CoA hydratase. Biochem Biophys Res Commun (1995) 0.78
The long-chain 3-hydroxyacyl-CoA dehydrogenase of human liver mitochondria. J Inherit Metab Dis (1991) 0.77
Prostaglandins which elevate cyclic AMP increase low density lipoprotein receptor mRNA and activity in human extra-hepatic cells. Biochem Soc Trans (1995) 0.77
Elevation of serum high density lipoprotein cholesterol by rowachol, a proprietary mixture of six pure monoterpenes. Atherosclerosis (1980) 0.77
Agents which increase cyclic AMP have diverse effects on low-density-lipoprotein-receptor function in human vascular smooth-muscle cells and skin fibroblasts. Biochem J (1990) 0.77
Acetoacetyl CoA thiolase deficiency presenting as ketotic hypoglycemia. Pediatr Res (1987) 0.77
3-Hydroxy-3-methylglutaryl-CoA synthase from baker's yeast. Methods Enzymol (1975) 0.76
Transient elevation of cAMP by prostaglandins triggers subsequent up-regulation of LDL receptor activity in cultured human cells. Biochem Soc Trans (1994) 0.76
Control of mitochondrial beta-oxidation: sensitivity of the trifunctional protein to [NAD+]/[NADH] and [acetyl-CoA]/[CoA]. Biochim Biophys Acta (1998) 0.76
Modulation by cellular cholesterol of gene transcription via the cyclic AMP response element. Biochem Pharmacol (2001) 0.76
Diurnal variation in the fraction of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in the active form in the mammary gland of the lactating rat. Biochem J (1986) 0.76
Urinary excretion of 2-methylacetoacetate, 2-methyl-3-hydroxybutyrate and tiglylglycine after isoleucine loading in the diagnosis of 2-methylacetoacetyl-CoA thiolase deficiency. J Inherit Metab Dis (1991) 0.76
Studies on a stable, mild diabetes induced by streptozotocin in rats. Br J Exp Pathol (1982) 0.75
The existence of oxoacyl-coenzyme A thiolases of differing substrate specificity and intracellular localization in mammalian tissues. Biochem J (1971) 0.75
Acetoacetyl-coenzyme A thiolases in rat brain during postnatal development. Biochem J (1971) 0.75
The effects of 3,5,5-trimethylcyclohexanol on hepatic cholesterol synthesis, bile flow and biliary lipid secretion in the rat. Br J Pharmacol (1984) 0.75
A case of 2-methylacetoacetyl CoA thiolase deficiency with coincidental chromosome abnormalities. J Med Genet (1984) 0.75
A mevalonate requirement for maintenance of fatty acid and protein synthesis during hormonally stimulated development of mammary gland in vitro. J Biol Chem (1984) 0.75
The inhibition of cholesterol esterification by cyclandelate in transformed mouse macrophages. Biochem Pharmacol (1993) 0.75
Use of an electronic medical record in disease management programs: a case study in hyperlipidemia. Stud Health Technol Inform (2001) 0.75
The effects of monocyclic terpenes on hepatic S-3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo [proceedings]. Biochem Soc Trans (1979) 0.75
Elimination of glucose interference and improved precision in a continuous-flow analysis for inulin. Clin Chem (1977) 0.75
Keeping patients active and current in a patient portal. AMIA Annu Symp Proc (2005) 0.75
Control of mitochondrial beta-oxidation at the levels of [NAD+]/[NADH] and CoA acylation. Adv Exp Med Biol (1999) 0.75
Inhibition of atherosclerosis in the rabbit by cyclandelate. Br J Clin Pract Suppl (1984) 0.75
Clinical benchmarking enabled by the digital health record. Stud Health Technol Inform (2001) 0.75
A unique, membrane-bound, multifunctional enzyme from human liver mitochondria catalysing three steps of fatty acid beta-oxidation. Biochem Soc Trans (1993) 0.75
Cyclandelate. An inhibitor of cholesterol esterification. Drugs (1987) 0.75
Students' animal welfare society. Vet Rec (2000) 0.75
The anomalous inhibition of shikimate dehydrogenase by analogues of dehydroshikimate. Biochim Biophys Acta (1972) 0.75
Characterization of the LDL receptor in rat promegakaryoblasts in culture. Biosci Rep (1991) 0.75
Cyclohexanol and methylcyclohexanols. A family of inhibitors of hepatic HMGCoA reductase in vivo. Biochem Pharmacol (1986) 0.75
3-Oxoacyl-coenzyme A thiolases and L-3-hydroxyacyl-coenzyme A dehydrogenases. Biochem Soc Trans (1978) 0.75
The existence of two different L-3-hydroxyacyl-coenzyme A dehydrogenases in rat tissues [proceedings]. Biochem Soc Trans (1979) 0.75